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Introduction
The complicated gallstone disease; common bile duct stones; common bile duct histopathology; major duodenal papilla disorders;
The peptic ulcer development mechanisms; refractory peptic ulcer treatment;
The gallbladder comparative anatomy;
The portal system comparative anatomy;
various
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Additional affiliations
January 2000 - April 2016
Publications
Publications (34)
A preliminary experimental study: Measurement of exocrine pancreatic secretion was performed on Wistar rats after an induction of acute pancreatitis by ‘closed duodenal loop’ (CDL) method (total number of animals = 39). After 24 hrs duration of AP the CDL content was evacuated by syringe and tested for amylase level (IU/ml). A near normal output re...
Background
To validate a new practical Sepsis Severity Score for patients with complicated intra-abdominal infections (cIAIs) including the clinical conditions at the admission (severe sepsis/septic shock), the origin of the cIAIs, the delay in source control, the setting of acquisition and any risk factors such as age and immunosuppression.
Metho...
Introduction:
Reports of a giant gallbladder are rare.
Presentation of case:
A 77-year-old woman was admitted with complaints of dull pain in the right half of the abdomen and a palpable mass at the same place. A computerized tomography scan revealed an extremely enlarged gallbladder. Open cholecystectomy was performed. The volume of the removed...
This article reviews the history of the gallbladder congenital absence(GCA) investigations. One of the rarest congenital anomaly in human biliary system is credited to be described for the first time by French scientists and physiceans Nicolas (or his son Louis?) Lemery (1701) and A.Littre (1705).
A list of GCA in adults contains 175 cases in the l...
The gallbladder agenesis is a rare congenital anomaly occuring in 4 to 6 per 10,000 births, but may become symptomatic more frequently, so that to be an accidental finding in up to 1:190-250 cholecystectomies in some reports.
Among of 126 case reports (among the adults) published from 1967 to 2012, choledocholithiasis was found in 20%. Coexisting...
Borodach AV & Pupyshev AB. Comparative Levels of the Splenic and the Systemic Total Bilirubin in the Wistar Rat (a preliminary report). In: A collection of works of the Interregional Science and Practical Workshop on Surgery. Omsk, Omsk State Medical Academy, 2013: 208-13.
Introduction: Alpha-IX-Bilirubin is the main product of the heme catabolism...
Ulcer Disease: State of the Art
Current concept of the peptic ulcer disease: Does it really exist?
Theories of the peptic ulcer disease are briefly discussed. Virchow paradox (“The roundish pattern suggests the very local cause for the ulcer to develop”), ‘double control mechanism’, ‘steal phenomenon’, nodular metaplasia ulceration hypotheses, exp...
Some species of animals possess the gallbladder, and some not. The comparative anatomy of the gallbladder among the vertebrates groups will be reviewed from the point of view on the post-cholecystectomy syndrome devolopment. 2 colour figures.
In clinic they are studing peculiarities of early postoperative period in patients with ventral hernia repair using different polypropylene prosthetic mesh placement were studied. Observations were made with regards to complications analysis, surgical trauma course, duration of operation and mesh consumption. Effectivety of sublay and underlay pros...
A prospective randomized study of 67 cases of the acute calculous cholecystitis without common bile duct stones was carried out. The total serum bilirubin was 48.2+-21.5 mcmol/L in the phlegmonous cholecystitis and 51.5+-16.2 mcmol/L in the gangrenous cholecystitis (q>0.1). Ductal bile samples were positive in 14 from 15 patients with hyperbilirune...
A randomized bacteriological and biochemical study of the gallbladder bile and gastroduodenoscopy with gastrobiopsy were performed in 48 patients with the acute phlegmonous (‘purulent’) cholecystitis (AFC), 17 patients with the acute gangrenous cholecystitis (AGC), and 12 patients with the acute superficial cholecystitis (ASC) from the total number...
The bacterial flora and micromorphology of the common bile duct in choledocholithiasis and cholangitis
AV.Borodach, SG.Shtofin, AL.Popov, AT.Oleynikova, DV.Morozov, IE.Sudovykh, and VN.Il’ina
The retrospective study of the microbial colonization of the choledocheal bile (obtained either during endoscopic papillotomy or in the course of the conventi...
An analysis of surgical treatment of cholelithiasis, acute cholecystitis was made which had appeared in 107 patients against the background of chronic diseases of the liver. Current diagnostic methods were used for differential diagnostics of jaundice: USI, CT, retrograde cholecystopancreatography, duodenoscopy. All the patients were operated upon...
Retrospective analysis of 3088 charts 1993-2003 with the acute cholecystitis were unrolled. Among the patients, 84.3% were operated upon due to the urgent indications, and 1569 had had destructive forms of the disease due to stone obstruction. From this group, 1204 patients experienced at oncet of the acute cholecystitis uncertain pain in the epiga...
Results of 1212 consecutive endoscopic papillosphincteromies performed for urgent indications were analysed. Common difficult situations and pitfalls, early specific complications and ways of their management are discussed
The comparative analysis of endoscopic findings and treatment results of 707 consequtive patients with the post-cholecystectomy syndrome and benign bile ducts diseases from 1990 till 2002 was performed. There were 2 groups formed: the main one included 336 patients with post-cholecystectomy syndrome, and a control one consisted of 371 patients with...
Surgical treatment of cholelithiasis in 485 elderly and aged patients operated from 1991 to 2000 are analyzed. Patients with acute inflammation in the biliary tract underwent surgery after standard conservative therapy during 12-48 hours after hospitalization. Methods of completion of surgery on the biliary tract are proposed: treatment of the bile...
Musculature and vasculature, innervation and micromorphological data were reviewed, including its typical anomalies of development and aquired alterations of the major duodenal papilla focused on the benign papillostenosis concept and diagnostics. Theories of the sphincter of Oddi role as a permanent (R.Oddi &E.A.Boyden) or scintillational (J.Tooul...
Investigations of the early pathologic and physiologic changes in the papilla Vateri, liver, pancreas, and duodenum are considered as a key to the early specific complications reasons understanding after papillosphincterotomy. A chronic experimental study in 22 adult mongrel dogs was carried out in purpose to investigate the early post-operative pe...
A comparative analysis of the results of using the ultrasonic investigation and computed tomography in differential diagnosis of jaundice was made in 205 patients. The reliability of USI in diagnosis of cholelithiasis was 54.3%, and that of standard CT was 55.9%. The authors have developed and used computed tomocholangiography (direct and indirect)...
The viscosity of some routine hydrosoluble contrast media used in operational cholangiography (Bilignost and Verographin) was studied. The different viscosity of hepatic and vesical bile and of the contrast media was determined. This fact shows that the data of any direct cholangiography in accordance with the law of Hagen-Poiseuille is misinterpre...
Cholangiography used with oral or intravenous contrast agents has gained wide acceptance as the most objective preoperative diagnostic technique for choledocholithiasis. However, an indirect contrasting technique has been found quite unfit in patients with severe bilirubinemia. Despite this, the authors employed indirect contrasting of the bile duc...
The article analyses surgical treatment of patients with cholelithiasis (231 persons) who were operated on with the use of a "pure" epidural block (59 patients), epidural block in combination with surface endotracheal nitrous oxide anaesthesia (100 patients), and general many--component anaesthesia (72 patients). The results show that epidural bloc...
The authors have shown that peridural blockade used in surgical interventions in patients with mechanical jaundice does not aggravate hepatic insufficiency diagnosed before the operation and facilitates earlier normalization of liver functions in the nearest postoperative period.
In patients operated upon with the use of peridural blockade the concentration of 11-OCS in blood plasma does not exceed the normal values both during surgery and in the immediate postoperative period. In patients operated upon under conditions of the routine combined narcosis an increased secretion of corticosteroids was observed.
Questions
Questions (31)
In the year of 1966, Adam & Metcalf performed and suggested a way of the common hepatic duct repair with a flap spared of gallbladder wall if it viable (as shown on the picture below). The procedure looks like quite feasible and witty therapeutic decision for Mirizzi’s types II-III or even IV repair, especially in case of emergency. However, does anyone have personal experience of that kind of choledochoplasty? Have anyone met a bile leakage or scar stricture developed after the Adam-Metcalf choledochoplasty?
Ref: Adam Y. & Metcalf W. Absence of the Cystic Duct: A Case Report, The Embryology and a Review of the Literature. Annals of Surgery 1966, vol.164, n.6, p.1056-1058
Hepatic venous pressure gradient is one of the main predictors of and the basic hydrodynamic reason for life-threatening bleeding in cirrhotic patients. It has been commonly admitted from the 90s that varices develop at a HVPG higher than 12 mmHg, and the higher HVPG the more frequent the patients tend to bleed. HPVG > 20 mmHg is considered as a significant prognostic indicator for bleeding from EVs to occur.
However, what was the highest portal pressure you have ever measured in your practice and have you encountered any special difficulty to achieve hemostasis in that case?