Andrew D. C. Maccoll

• PhD University of Aberdeen
• Professor (Full) at University of Nottingham

The three-spined stickleback (Gasterosteus aculeatus) is a teleost fish and a model organism in evolutionary ecology, useful for both laboratory and natural experiments. It is especially valued for the substantial intraspecific variation in morphology, behaviour and genetics. Classic work of Swarup (1958) has described the development in the labora...

Rising water temperatures in rivers due to climate change are already having observable impacts on river ecosystems. Warming water has both direct and indirect impacts on aquatic life, and further aggravates pervasive issues such as eutrophication, pollution, and the spread of disease. Animals can survive higher temperatures through physiological a...

Contact zones between divergent forms within a species provide insight into the role of gene flow in adaptation and speciation. Previous work has focused on contact zones involving only two divergent forms, but in nature, many more than two populations may overlap simultaneously and experience gene flow. Patterns of introgression in wild population...

The three-spined stickleback ( Gasterosteus aculeatus) is a teleost fish and a model organism in evolutionary ecology, useful for both laboratory and natural experiments. It is especially valued for the substantial intraspecific variation in morphology, behaviour and genetics. Classic work of Swarup (1958) [1] has described the development in the l...

Rapid evolution of similar phenotypes in similar environments, giving rise to in situ parallel adaptation, is an important hallmark of ecological speciation. However, what appears to be in situ adaptation can also arise by dispersal of divergent lineages from elsewhere. We test whether two contrasting phenotypes repeatedly evolved in parallel, or h...

The context and cause of adaptive radiations have been widely described and explored but why rapid evolutionary diversification does not occur in related evolutionary lineages has yet to be understood. The standard answer is that evolutionary diversification is provoked by ecological opportunity and that some lineages do not encounter the opportuni...

Submersion in the anaesthetic MS-222 is a well-established and effective method used during the euthanasia of fish, but the consequences of treatment with this anaesthetic for mitochondrial respiration are yet to be established. This is important to evaluate, as an increasing amount of research is conducting high-resolution respirometry to measure...

Rapid evolution of similar phenotypes in similar environments, giving rise to in situ parallel adaptation, is an important hallmark of ecological speciation. However, what appears to be in situ adaptation can also arise by dispersal of divergent lineages from elsewhere. We test whether two contrasting phenotypes repeatedly evolved in parallel, or h...

The context and cause of adaptive radiations has been widely described and explored but why rapid evolutionary diversification does not occur in related evolutionary lineages has yet to be understood. One possible answer to this is simply that evolutionary diversification is provoked by environmental diversity, and that some lineages do not encount...

Adaptation to derived habitats often occurs from standing genetic variation (SGV). The maintenance within ancestral populations of genetic variants favorable in derived habitats is commonly ascribed to long‐term antagonism between purifying selection and gene flow resulting from hybridization across habitats. A largely unexplored alternative idea b...

Understanding the implications of climate change for migratory animals is paramount for establishing how best to conserve them. A large body of evidence suggests that birds are migrating earlier in response to rising temperatures, but many studies focus on single populations of model species. Migratory patterns at large spatial scales may differ fr...

Adaptation to derived habitats often occurs from standing genetic variation (SGV). The maintenance within ancestral populations of genetic variants favorable in derived habitats is commonly ascribed to long-term antagonism between purifying selection and gene flow resulting from hybridization across habitats. A largely unexplored alternative idea b...

Parallelism, the evolution of similar traits in populations diversifying in similar conditions, provides strong evidence of adaptation by natural selection. Many studies of parallelism focus on comparisons of different ecotypes or contrasting environments, defined a priori, which could upwardly bias the apparent prevalence of parallelism. Here, we...

The maintenance of reproductive isolation in the face of gene flow is a particularly contentious topic, but differences in reproductive behavior may provide the key to explaining this phenomenon. However, we do not yet fully understand how behavior contributes to maintaining species boundaries. How important are behavioral differences during reprod...

• Quantitative PCR (qPCR) has been commonly used to measure gene expression in a number of research contexts, but the measured RNA concentrations do not always represent the concentrations of active proteins which they encode. This can be due to transcriptional regulation or post‐translational modifications, or localization of immune environments,...

Seasonal disease and parasitic infection are common across organisms, including humans, and there is increasing evidence for intrinsic seasonal variation in immune systems. Changes are orchestrated through organisms' physiological clocks using cues such as day length. Ample research in diverse taxa has demonstrated multiple immune responses are mod...

Parallelism, the evolution of similar traits in populations diversifying in similar conditions, provides good evidence of adaptation by natural selection. Many studies of parallelism have focused on comparisons of strongly different ecotypes or sharply contrasting environments, defined a priori, which could upwardly bias the apparent prevalence of...

The composition of the mammalian gut microbiota can be influenced by a multitude of environmental variables such as diet and infections. Studies investigating the effect of these variables on gut microbiota composition often sample across multiple separate populations and habitat types. In this study we explore how variation in the gut microbiota o...

Ecological speciation has become a popular model for the development and maintenance of reproductive isolation in closely related sympatric pairs of species or ecotypes. An implicit assumption has been that such pairs originate (possibly with gene flow) from a recent, genetically homogeneous ancestor. However, recent genomic data has revealed that...

Resource availability and predation are supposed to be the most important ecological factors shaping age at maturation. They are expected to have a similar effect in causing populations to mature earlier, but a contrasting effect on size at maturation. Higher resources have a positive effect on size at maturation by increasing growth rate, while he...

The ability, propensity and need to mount an immune response vary both among individuals and within a single individual over time. A wide array of parameters has been found to influence immune state in carefully controlled experiments, but we understand much less about which of these parameters are important in determining immune state in wild popu...

the switch from egg-laying to retaining and giving birth to live young is a major transition in the history of life. Despite its repeated evolution across the fishes, records of intermediate phenotypes are vanishingly rare, with only two known cases in existence of normally egg-laying fish species retaining embryos within the ovaries. We report the...

The switch from egg-laying to retaining and giving birth to live young is a major transition in the history of life. Despite its repeated evolution across the fshes, records of intermediate phenotypes are vanishingly rare, with only two known cases in existence of normally egg-laying fsh species retaining embryos within the ovaries. We report the d...

Genomic studies of parallel (or convergent) evolution often compare multiple populations diverged into two ecologically different habitats to search for loci repeatedly involved in adaptation. Because the shared ancestor of these populations is generally unavailable, the source of the alleles at adaptation loci, and the direction in which their fre...

Method. Discussion. Table S1. Description of study habitats and populations. Table S2. All pairwise populations comparisons (AFD and FST). Table S3. Pairwise comparisons per habitat (AFD and FST). Table S4. List of genes around the top core SNPs. Table S5. Characterization of the 42 core SNPs. Figure S1. Schematic description of the SNP gene...

DNA breakage and adaptation Adaptation to new environments often occurs in similar ways across different colonization events. Stickleback fish represent a classic example of this, in which repeated colonizations of freshwater have resulted in the loss of pelvic hind fins. Previous work has shown that a pelvic enhancer gene is involved. Xie et al. n...

This paper critiques Jones & Hynes (1950) findings by analysing sequential samples of otoliths from three wild populations of Gasterosteus aculeatus from North Uist, Scotland and Nottingham, England. Contrary to Jones & Hynes (1950), but coincident with the finding of later researchers, our results showed that no true translucent ring formed in the...

Understanding how wild immune variation covaries with other traits can reveal how costs and trade‐offs shape immune evolution in the wild. Divergent life history strategies may increase or alleviate immune costs, helping shape immune variation in a consistent, testable way. Contrasting hypotheses suggest that shorter life histories may alleviate co...

In Europe, woodland bird populations have been declining since at least the 1970s, and in Britain, around one third of woodland bird species have undergone declines over this period. Habitat change has been highlighted as a possible cause, but for some species clear evidence of this is lacking owing to an incomplete knowledge of the species’ habita...

The comment by Myers-Smith and Myers focuses on three main points: (i) the lack of a mechanistic explanation for climate-selection relationships, (ii) the appropriateness of the climate data used in our analysis, and (iii) our focus on estimating climate-selection relationships across (rather than within) taxonomic groups. We address these critique...

Although many selection estimates have been published, the environmental factors that cause selection to vary in space and time have rarely been identified. One way to identify these factors is by experimentally manipulating the environment and measuring selection in each treatment. We compiled and analyzed selection estimates from experimental stu...

Parasite virulence varies greatly. Theory predicts that this arises from parasites optimising a trade‐off between the mortality they inflict on current hosts, and their transmission to future hosts. The effect of the environment on this co‐evolution is rarely considered. Geographic mosaics are fertile systems for studying co‐evolution, but again, t...

Haplotypes underlying local adaptation and speciation are predicted to have numerous phenotypic effects, but few genes involved have been identified, with much work to date concentrating on visible, morphological, phenotypes. The link between genes controlling these adaptive morphological phenotypes and the immune system has seldom been investigate...

Climate-driven selection Climate change will fundamentally alter many aspects of the natural world. To understand how species may adapt to this change, we must understand which aspects of the changing climate exert the most powerful selective forces. Siepielski et al. looked at studies of selection across species and regions and found that, across...

Climate change has the potential to affect the ecology and evolution of every species on Earth. Although the ecological consequences of climate change are increasingly well documented, the effects of climate on the key evolutionary process driving adaptation - natural selection - are largely unknown. We report that aspects of precipitation and pote...

Parasitism represents one of the most widespread lifestyles in the animal kingdom, with the potential to drive coevolutionary dynamics with their host population. Where hosts and parasites evolve together, we may find local adaptation. As one of the main host defences against infection, there is the potential for the immune response to be adapted t...

Patterns in parasite community structure are often observed in natural systems and an important question in parasite ecology is whether such patterns are repeatable across time and space. Field studies commonly look at spatial or temporal repeatability of patterns, but they are rarely investigated in conjunction. We use a large dataset on the macro...

In western Tanzania?s wildlife ecosystems, both commercial and subsistence uses of wildlife take place. Commercial use is largely through trophy hunting in designated hunting areas while subsistence use is predominantly carried out by local people for food and as a source of cash income. Assessing the status of wildlife populations in hunting areas...

Spatial variation in parasitic infections is common, and has the potential to drive population divergence and the reproductive isolation of hosts. However, despite support from theory and model laboratory systems, little strong evidence has been forthcoming from the wild. Here, we show that parasites are likely to cause reproductive isolation in th...

There has been a large focus on the genetics of traits involved in adaptation, but knowledge of the environmental variables leading to adaptive changes is surprisingly poor. Combined use of environmental data with morphological and genomic data should allow us to understand the extent to which patterns of phenotypic and genetic diversity within a s...

The genetic diversity and population structure of a parasite with a complex life cycle generally depends on the dispersal by its most motile host. Given that high gene flow is assumed to hinder local adaptation, this can impose significant constraints on a parasite's potential to adapt to local environmental conditions, intermediate host population...

Analysing spatial differences among macroparasite communities is an important tool in the study of host–parasite interactions. Identifying patterns can shed light on the underlying causes of heterogeneity of parasite distribution and help to better understand ecological constraints and the relative importance of host and parasite adaptations. In th...

uestion: How do immune phenotypes differ between infected and uninfected wild individuals, and is the effect the same in different populations? Organisms: Threespine stickleback (Gasterosteus aculeatus) from two lake populations on the island of North Uist, Scotland, sampled in May 2015. Methods: For each fish, we recorded length, sex, reproductive...

Current understanding of the immune system comes primarily from lab-based studies. There has been substantial interest in examining how it functions in the wild, but studies have been limited by a lack of appropriate assays and study species. The three-spined stickleback (Gasterosteus aculeatus L.) provides an ideal system in which to advance the s...

Illegal exploitation of wildlife for bushmeat is a widespread problem affecting many ecosystems especially in the Tropics. Understanding the factors associated with such exploitation may help in the management of the problem by conservationists. Although there is a substantial problem of wildlife poaching in east Africa, the factors that affect its...

In a recent paper in this journal, Spence et al. (2013) sought to identify the ecological causes of morphological evolution in three-spined sticklebacks Gasterosteus aculeatus, by examining phenotypic and environmental variation between populations on the island of North Uist, Scotland. However, by using simple qualitative assessments of phenotype...

Illegal harvesting of wildlife resources is an important challenge facing protected areas in Africa. A better understanding of its nature would improve the way in which it is managed. We investigated the degree of poaching into different types of natural resources and its management implications in Ugalla Game Reserve, western Tanzania, using data...

Sustainable legal subsistence hunting has a place in conservation. Nonetheless, the long-term success of such schemes depends on them being well managed. We assessed the effectiveness of legal subsistence hunting in the Ugalla ecosystem of western Tanzania using data from the local legal hunting scheme. The hunting in the ecosystem is conducted wit...

Woodland birds have experienced widespread population declines across Europe, resulting partly from a decrease in management practices such as coppicing. Increasing fuelwood demand may reverse the decline of coppicing, making it timely to attempt a fuller understanding of its effects. Here, the impact of coppicing on year-round habitat use by adult...

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It has been suggested that selection on melanocortin-1-receptor (MC1R) polymorphism, a common cause of melanic colour variation in vertebrates, results from pleiotropic effects of the gene in the immune system. Here we present the first test of whether MC1R variation is associated with differences in parasite abundance in a natural population. Bana...

Body size is a defining phenotypic trait, but the ecological causes of its evolution are poorly understood. Most studies have considered only a single putative causal agent and have failed to recognise that different environmental agents are often correlated. Darwin suggested that although trait variation across populations is often associated with...

SUMMARY Parasite ecologists are often interested in the repeatability of patterns in parasite communities in space and/or time, because of implications for the dynamics of host-parasite interactions. Field studies usually examine temporal and spatial variation in isolation or limit themselves to a small number of host populations. Here, we studied...

Predation can promote divergence between prey populations and contribute to ecological speciation. In theory, predators can also constrain prey population divergence. In coastal British Columbia, Canada, Gasterosteus aculeatus (three-spined stickleback) species pairs only occur in lakes with a single species of predatory fish: Oncorhynchus clarkii...

Natural selection is the process that results in adaptive evolution, but it is not the cause of evolution. The cause of natural selection and, therefore, of adaptive evolution, is any environmental factor (agent of selection) that results in differential fitness among phenotypes. Surprisingly little is known about selective agents, how they interac...

1. Given their ubiquity, we might expect parasites to play an important role in the adaptive divergence of host populations. Specifically, adaptation to local parasite communities is predicted to influence the evolution of a number of host traits such as parasite resistance. 2. To investigate the possibility that divergent parasite-mediated selecti...

In the Ugalla ecosystem, wildlife conservation is constantly and pervasively challenged by the local communities looking for ways to improve their livelihoods. The need to curb poaching of wildlife continues to spark debate amongst conservation stakeholders in the area. Assessing the livelihood contributions of different sources of income in light...

1. The potential for selection against migrants to promote population divergence and speciation is well established in theory, yet there has been relatively little empirical work that has explicitly considered selection against migrants as a form of reproductive barrier, and its importance in the accumulation of reproductive isolation between popul...

In the past decade, there has been a new effort to understand the ecology that drives population divergence and speciation. It is well established in theory that speciation is most likely to occur when a trait that is under divergent natural selection in different populations is also used in mate choice. Such traits have been dubbed ‘magic traits’...

The ecological theory of adaptive radiation states that differences in ecological circumstances among local populations are the cause of divergence that leads to speciation. The role of parasites in contributing to divergence has seldom been considered, despite their ubiquity and known selective effects. The potential for parasites to contribute to...

Populations of red grouse (Lagopus lagopus scoticus) undergo regular multiannual cycles in abundance. The 'kinship hypothesis' posits that such cycles are caused by changes in kin structure among territorial males producing delayed density-dependent changes in aggressiveness, which in turn influence recruitment and regulate density. The kinship hyp...

Several aspects of the ecology and biology of red grouse (Lagopus lagopus scoticus) could prevent the complete admixture of genes within and between populations. Male red grouse display a high degree of natal philopatry, are territorial, and show less aggression to kin man to non-kin. Such factors acting in combination predict limited male-mediated...

We analysed 16years of census data gathered on the island of Hirta (archipelago of St. Kilda) to investigate the effects of castration, population density, sex ratio, season and group type on habitat use and social segregation of Soay sheep. From 1978 to 1980, 72 male lambs were castrated. We used this experiment to study how a change in reproducti...

Summary 1. Long-tailed tits ( Aegithalos caudatus ) are a cooperatively breeding species in which helpers often invest effort in the provisioning of young that are not their own. 2. We quantified the lifetime reproductive success (LRS) and the individual fitness, lambda, of 228 long-tailed tits using 8 years of field data. Calculation of lambda too...

Helpers at the nest in the cooperative breeding system of long-tailed tits Aegithalos caudatus exhibit kin preference in their helping behavior. The aim of this study was to use multivariate analyses to investigate whether helpers accrue indirect fitness benefits through their cooperation by increasing the productivity of relatives. All birds start...

Soay Sheep synthesises one of the most detailed studies of demography and dynamics in a naturally regulated population of mammals. Unlike most other large mammals, the Soay sheep population of Hirta in the St Kilda archipelago show persistent oscillations, sometimes increasing or declining by more than 60% in a year. Soay Sheep explores the causes...

Soay Sheep synthesises one of the most detailed studies of demography and dynamics in a naturally regulated population of mammals. Unlike most other large mammals, the Soay sheep population of Hirta in the St Kilda archipelago show persistent oscillations, sometimes increasing or declining by more than 60% in a year. Soay Sheep explores the causes...

The optimal investment strategies of parents in biparental systems are well studied. This contrasts with a poor theoretical and empirical understanding of variation in individual investment in breeding systems with multiple carers. We used the cooperative breeding system of long-tailed tits, to investigate how parents and helpers adjust their rate...

Bananaquits (Coereba flaveola) on the island of Grenada in the West Indies have a plumage color polymorphism in which individuals are either yellow and black or all black. In the southwest of the island there is a cline in plumage morphs in which the frequency of black individuals increases with distance from the island's southwestern tip. We descr...

Bananaquits (Coereba flaveola) on the island of Grenada in the West Indies have a plumage color polymorphism in which individuals are either yellow and black or all black. In the southwest of the island there is a cline in plumage morphs in which the frequency of black individuals increases with distance from the island's southwestern tip. We descr...

The study of the evolution of parental care is central to our understanding of social systems, sexual selection, and interindividual conflict, yet we know virtually nothing about the genetic architecture of parental care traits in natural populations. In this paper, we use data from a long term field study of a passerine bird, the long-tailed tit (...

Cooperative breeding is paradoxical because some individuals forego independent reproduction and instead help others to reproduce. The ecological constraints model states that such behavior arises because of constraints on independent reproduction. Spatial variation in constraints has been shown to co-vary with the incidence of cooperative breeding...

Cooperative breeding is paradoxical because some individuals forego independent reproduction and instead help others to reproduce. The ecological constraints model states that such behavior arises because of constraints on independent reproduction. Spatial variation in constraints has been shown to co‐vary with the incidence of cooperative breeding...

Models have shown that population cycles might be driven by time lags resulting from positive feedback between kin structure and population change, coupled with negative feedback between density and population change. One such model operates through kin favouritism facilitating the recruitment of young cock red grouse. We investigated whether recru...

DNA sequence variation at the hypervariable 5' end of the mitochondrial control region was examined in 247 individuals to detect genetic divergence among 14 populations of red grouse (Lagopus lagopus scoticus) in northeastern Scotland. Ten haplotypes were resolved, several of which were shared among populations. Analysis of molecular variance, Nei'...

— DNA sequence variation at the hypervariable 5’end of the mitochondrial control region was examined in 247 individuals to detect genetic divergence among 14 populations of red grouse (Lagopus lagopus scoticus) in northeastern Scotland. Ten haplotypes were resolved, several of which were shared among populations. Analysis of molecular variance, Nei...

Variation in male lifetime breeding success (LBS) is central to understanding selection, yet it has rarely been measured in natural populations of large mammals. Here, we first describe variation in the opportunity for selection in cohorts of Soay rams (Ovis aries) on the archipelago of St. Kilda, Scotland, that were born during years of varying po...

1. In social mammals where group members cooperate to detect predators and raise young, members of small groups commonly show higher mortality or lower breeding success than members of large ones. It is generally assumed that this is because large group size allows individuals to detect or repel predators more effectively but other benefits of grou...

Summary In most respects, the demography of Kalahari suricates (Suricata suricatta) resembles that of other social mongooses. Average group size varies from four to nine, and groups typically include several mature females, of which one is responsible for the majority of breeding attempts. Breeding females show a postpartum oestrus; gestation is ar...

Allelic variation at seven hypervariable tri- and tetranucleotide microsatellite loci was used to determine levels of population differentiation between 14 populations of red grouse (Lagopus lagopus scoticus) in northeast Scotland, UK. Despite the potential for long-distance dispersal in grouse, and a semicontinuous habitat, significant population...

Functional interpretations of helping behaviour suggest that it has evolved because helpers increase their direct or indirect fitness by helping. However, recent critiques have suggested that helping may be an unselected extension of normal parental behaviour, pointing to evidence that all mature individuals commonly respond to begging young (wheth...

Thesis (Ph. D.)--University of Aberdeen, 1998.

While many populations of large mammals are stable from year to year, some show persistent oscillations associated with high mortality. This article investigates the causes of variation in population stability in ungulates by comparing the contrasting dynamics of two naturally regulated island populations: the Soay sheep population of Hirta (St. Ki...

1. Though models of life-history decisions are traditionally based on age-related changes in the costs and benefits of reproduction, in nature both costs and benefits vary with individual differences in phenotype as well as with environmental changes. 2. Using long-term records of individual reproduction and survival in the Soay sheep of St Kilda,...

Theoretical models of the effect of population bottlenecks on genetic variation assume that individuals are removed at random from the population. We investigated this assumption in a naturally regulated, unstable population of Soay sheep (Ovis aries). During rapid population declines or 'crashes', individuals were not removed at random with respec...

Current models of lek breeding mostly suggest that males defend clustered mating territories because females show a preference for mating on leks. Here we argue that, in lek-breeding ungulates, males may also gain benefits from holding clustered mating territories because clusters retain does in estrus. We show that in fallow deer (Dama dama) harem...