Andrew E. Ivang

University of Rwanda · Clinical Anatomy

Background Tamarindus indica (TI) extract is known to possess important phytochemical composition. The study aimed to assess the effects of ethyl acetate fraction of TI leaves (EATI) on memory and learning, traced element and brain sialic acid levels, and hippocampal Nissl substance expression following prenatal (PN) AlCl3 exposure in Wistar rat pu...

INTRODUCTION: Human anatomy is a cornerstone of medical practice hence teaching modalities should be strengthened. Major challenges were faced in this COVID-19 era when the teaching aspect was considered. The use of eLearning and blended learning is an innovative delivery mode to enhance medical education efficiency in the pandemic era. This study...

Introduction: The knowledge of anatomy is essential for surgical safety and impacts positively on patients' outcomes. Surgeons operating on the liver and bile ducts should keep in mind the normal anatomy and its variations as the latter are common. Case presentation: We conducted a structured surgical dissection course of the supra-colic compart...

Purpose: The recent increase in aluminum exposure and its effect on the development of the brain call for serious attention. The study investigated the behavioral and immunohistochemical changes in the cerebral cortex of Wistar rats following prenatal co-administration of ethyl acetate leaf fraction of Tamarindus indica (EATI) and aluminum chloride...

Bacterial infections pose a global threat, especially in the pediatric population. Antimicrobials that are used to treat such infections continuously show reduced efficacy, and empirical therapy is a major treatment option in Rwanda. This study aimed to determine the resistance rate of commonly used antibiotics in pediatric patients. The study was...

Introduction: The brachial plexus is highly variable, which is a well-known anatomical fact. Repeated observations on anatomical variations, however, constitute current trends in anatomical research. Case series: In an anatomical dissection course, three uncommon variations in the brachial plexus were identified in three young adults' cadavers....

Context: Mercury is a widespread environmental and industrial pollutant that exerts toxic effects on vital organs. The cerebrum, composed of cortical areas such as the primary motor cortex (M1), is a vulnerable target of mercury toxicity within the central nervous system. Phoenix dactylifera is used in folk medicine to treat diverse disorders, such...

A total of twelve pregnant Wistar rats were used, and randomly divided into three groups (n=4). Group A (negative control), not exposed to noise stress), group B (1mL/kg of distilled water + 4h /15 days noise stress), group C (0.04 mg/kg) of selenium-yeast + 4 h/15 days noise stress). On day 18 and 19 of gestation cognitive tests were conducted usi...

Mercury is an environmental neurotoxicant that triggers structural and physiological alterations in different brain parts. The hippocampus is associated with learning and memory, and injury to this brain part may lead to behavioural and cognitive changes. Phoenix dactylifera (date palm) has been demonstrated to possess a variety of medical benefits...

Lead is a highly toxic substance, exposure to which can produce a wide range of adverse health effects on humans including neurological conditions. Phoenix dactylifera (date palm) is of vast medicinal and nutritious values. This study assessed the neuroprotective effect of methanol fruit pulp extract of Phoenix dactylifera (MFPD) following lead ace...

Background Healthcare service delivery systems all over the world is need to ensure standard quality of care for achieving expected health outcomes. Although Rwanda has a reputation in good healthcare service delivery system, there are still major concerns about the quality of maternal and newborn health (MNH) care services. The purpose of this stu...

Context: Mercury is a widespread environmental and industrial pollutant that exerts toxic effects on vital organs. The cerebrum, composed of cortical areas such as the primary motor cortex (M1), is a vulnerable target of mercury toxicity within the central nervous system. Phoenix dactylifera is used in folk medicine to treat diverse disorders, such...

Over the years, Formaldehyde (FA) has been linked to increased generation of reactive oxygen species (ROS), leading to oxidative stress and cognitive decline. However limited numbers of studies have shown the effect of eugenol on FA induced toxicity in Wistar rats. Therefore this study aimed at investigating the effects of eugenol on the FA induced...

Sclerocarya birrea (S. birrea) is a tropical plant used traditionally in the management of a variety of ailments. Many reports have been made scientific literatures suggesting its therapeutic usefulness. The present study was therefore carried out to evaluate the safety of acetone extract of S. birrea by acute and sub-acute toxicity studies. Acute...

Ethanol consumption has been linked with social and medical problems, coupled with damage of multiple organs including the cerebellum. The present study is aimed at investigating the histological and biochemical changes in the cerebellum of Wistar rats associated with ethanol exposure. The experimental animals were grouped into five groups designat...

Artesunate is one of the first choice treatments among pregnant women with malaria in Nigeria as they are more susceptible and likely to develop anaemia and other complications. The present study was aimed to investigate the morphological and histological changes due to artesunate on the developing hypothalamus of Wistar rat fetuses. Twenty healthy...

This study assessed the effect of aqueous fruit extract of Phoenix dactylifera (AFPD) on anxiety and memory in mercury-intoxicated Wistar rats. Twenty-four rats were divided into six groups (I-VI; n=4). Group I (control) was administered distilled water (0.3ml) while, groups II-VI were treatment groups. Anxiety-like behaviour and memory alteration...

This study assessed the effect of aqueous fruit extract of Phoenix dactylifera (AFPD) on anxiety and memory in mercury-intoxicated Wistar rats. Twenty-four rats were divided into six groups (I-VI; n=4). Group I (control) was administered distilled water (0.3ml) while, groups II-VI were treatment groups. Anxiety-like behaviour and memory alteration...

Background of the study: Infertility is considered one of the main public health issues, as it affects about 15% of the couples of reproductive age. The male factor is involved in 40% - 50% of infertility cases In the recent times the use of herbal plants to enhance fertility is on the increase. Objectives: this study investigated the effects of Al...

The teratogenic influence of maternal administration of artesunate on the morphometry of foetal nervous system was studied. Twenty virgin female Wistar rats weighing between 200g and 230g were used for this study. The animals were divided into 4 groups of 5 rats each. Each group was kept in a separate plastic cage. The rats were fed with commercial...

The teratogenic influence of maternal administration of artesunate on the morphometry of foetal nervous system was studied. Twenty virgin female Wistar rats weighing between 200g and 230g were used for this study. The animals were divided into 4 groups of 5 rats each. Each group was kept in a separate plastic cage. The rats were fed with commercial...