Andrew Robert Beadling

• PhD
• Assistant Professor at University of Birmingham

Introduction While Total Disc Replacements (TDRs) are generally performing well clinically, reoperation rates indicate that the full potential of the TDR concept might not have been reached. Inspired by the underlying complications related to biomechanics and material longevity that limit the performance of current TDRs, we propose a methodology fo...

This study presents new insights into the potential role of polyelectrolyte interfaces in regulating low friction and interstitial fluid pressurization of cartilage. Polymer brushes composed of hydrophilic 3-sulfopropyl methacrylate potassium salt (SPMK) tethered to a PEEK substrate (SPMK-g-PEEK) are a compelling biomimetic solution for interfacing...

This biomechanical study aimed to determine if variations in stem material, stem geometry, stem offset and cement viscosity affect mechanical resistance to postoperative periprosthetic fracture (PFF) after hip arthroplasty with a commonly used cemented polished taper-slip (PTS) stem (CPT, Zimmer Biomet) in a novel osteoporotic composite femoral bon...

To enable long lasting osteochondral defect repairs which preserve the native function of synovial joint counter-face, it is essential to develop surfaces which are optimised to support healthy cartilage function by providing a hydrated, low friction and compliant sliding interface. PEEK surfaces were modified using a biocompatible 3-sulfopropyl me...

Fretting-corrosion at the modular taper junction in total hip replacements (THR), leading to implant failure, has been identified as a clinical concern and has received increased interest in recent years. There are many parameters thought to affect the performance of the taper junction, with the assembly process being one of the few consistently id...

Following the high clinical failure rates of metal-on-metal total hip replacements much work has been undertaken to investigate their poor performance. So called adverse loading scenarios such as acetabular inclination and microseparation have been attributed to indicators for failure of the implants. The ISO hip simulation standards (ISO 14242:1)...

A systematic literature review about corrosion on spinal instrumentation systems

Titanium cermet combining metallic toughness with ceramic wear resistance has been proven to be a potential candidate for implanted joint material. In this work, titanium cermet was synthesized by means of the elevated temperature solid carburizing technology. The Ti13Nb13Zr alloy surface was found to be converted into TiC ceramic layer combined wi...

Taper degradation in Total Hip Replacements (THR) has been identified as a clinical concern, and the degradation occurring at these interfaces has received increased interest in recent years. Wear and corrosion products produced at the taper junction are associated with adverse local tissue responses, leading to early failure and revision surgery....

Acoustic emission (AE) has been successfully used to investigate the damage mechanisms of fretting contacts within different regimes. This study investigated the transition between fretting regimes using the relationship between AE and the mechanical response of a dry, steel-on-steel, ball-on-flat contact under different tangential displacements ac...

A thorough investigation into the repassivation process of CoCrMo in multiple simulated biological environments has been undertaken, looking in detail at both the kinetics and composition of the reformed oxide film. Specific focus of this research was aimed at determining the effect of bovine serum albumin (BSA) on these features. The kinetics of r...

The re-passivation kinetics and composition of the passive film of CoCrMo alloys in simulated body fluids have been investigated, with key emphasis being to assess the effect that proteins have on these features. The kinetics were analyzed using potentiostatic polarization, applying a second order exponential decay to the current transients obtaine...

Interest in the degradation mechanisms at the modular tapers interfaces has been renewed due to increased reported cases of adverse reactions to metal debris and the appearance of wear and corrosion at the modular tapers interfaces at revision. Over the past two decades, a lot of research has been expended to understand the degradation mechanisms,...

The degradation of Metal-on-Metal (MoM) Total Hip Replacements (THRs) is a complex mix of tribological, corrosive phenomena and their synergistic processes. Previous links between the corrosion of these devices and their sliding conditions over a cycle have been observed in simulator studies instrumented with a three-electrode electrochemical cell....

Corrosion is not routinely considered in the assessment of the degradation or the lifetime of total hip replacement bearing surfaces. Biomechanical simulations are becoming ever more complex and are taking into account motion cycles that represent activities beyond a simple walking gait at 1 Hz, marking a departure from the standard ISO BS 14242. H...

The poor performance of Metal-on-Metal (MoM) bearings has to date been blamed on “adverse loading” conditions. Studies have focused on the effect of cup inclination and microseparation on gravimetric wear rates and highlighted the importance of surgical technique when implanting such devices. Up to four fold increase in the wear rates of MoM bearin...

The poor performance of Metal-on-Metal (MoM) bearings has to date been blamed on "adverse loading" conditions. Studies have focused on the effect of cup inclination and microseparation on gravimetric wear rates and highlighted the importance of surgical technique when implanting such devices. Up to four fold increase in the wear rates of MoM bearin...

In recent years, metal-on-metal (MoM) total hip replacements have been used as an alternative to the more popular metal-on-polymer prostheses. This can be attributed to the lower volumetric wear rate of MoM bearings, and their propensity to produce debris that is less prone to evoke an osteolytic response in patients when compared with MoP designs....