Andrej Thurzo

Comenius University Bratislava · Clinic of Stomatology and Maxillofacial Surgery

This literature research had two main objectives. The first objective was to quantify how frequently artificial intelligence (AI) was utilized in dental literature from 2011 until 2021. The second objective was to distinguish the focus of such publications; in particular, dental field and topic. The main inclusion criterium was an original article...

(1) Teeth, in humans, represent the most resilient tissues. However, exposure to concentrated acids might lead to their dissolving, thus making human identification difficult. Teeth often contain dental restorations from materials that are even more resilient to acid impact. This paper aims to introduce a novel method for the 3D reconstruction of d...

This paper introduces a novel method of 3D designing and 3D printing of a hybrid orthodontic tooth-borne personalized distalizer for treatment of unilateral Class II malocclusion. Research objectives were to clinically utilize 3D printed distalizers, appraise feasibility of this technique and compare two different biocompatible photopolymers (white...

Background: Treatment of malocclusion with clear removable appliances like Invisalign® or Spark™, require considerable higher level of patient compliance when compared to conventional fixed braces. The clinical outcomes and treatment efficiency strongly depend on the patient's discipline. Smart treatment coaching applications, like strojCHECK® are...

Background Traditional dental anatomy education, reliant on cadaver dissections and lectures, faces challenges such as high costs, ethical concerns, and difficulty conveying complex 3D dental structures. Virtual reality (VR) offers a solution by providing immersive, interactive learning environments that can enhance students’ understanding. This st...

Three-dimensional printing has transformed dentistry by enabling the production of customized dental restorations, aligners, surgical guides, and implants. A variety of polymers and composites are used, each with distinct properties. This review explores materials used in 3D printing for dental applications, focusing on trends identified through a...

Improving one’s appearance is one of the main reasons to undergo an orthodontic therapy. While occlusion is important, not just for long-term stability, aesthetics is often considered a key factor in patient’s satisfaction. Following recent advances in artificial intelligence (AI), this study set out to investigate whether AI can help guide orthodo...

This narrative review explores the potential, complexities, and consequences of using artificial intelligence (AI) to screen large government-held facial image databases for the early detection of rare genetic diseases. Government-held facial image databases, combined with the power of artificial intelligence, offer the potential to revolutionize t...

Regenerative dentistry has experienced remarkable advancement in recent years. The interdisciplinary discoveries in stem cell applications and scaffold design and fabrication, including novel techniques and biomaterials, have demonstrated immense potential in the field of tissue engineering and regenerative therapy. Scaffolds play a pivotal role in...

Abstract—The era of 3D printing of biocompatible personalized scaffolds has arrived, and Cone Beam Computed Tomography (CBCT) is essential for 3D reproduction of individualized human anatomy. When designing the shape of the personalized scaffold, the starting point is typically the CBCT scan, which must first be segmented to define the complementar...

In the age of artificial intelligence (AI), technological progress is changing established workflows and enabling some basic routines to be updated. In dentistry, the patient’s face is a crucial part of treatment planning, although it has always been difficult to grasp in an analytical way. This review highlights the current digital advances that,...

Reconstruction of a 3D eye model by photogrammetry from a smartphone video could be prospectively used in self-diagnosis, screening and telemedicine monitoring of diseases of the front part of the eye and its surroundings. The main use could be found in the treatment of diseases of the curvature and surface of the cornea and in follow-up after some...

Multiphase phosphate bioceramics are a promising class of materials that can meet various specific requirements in one single material. Tricalcium phosphate (TCP) is widely known for its biocompatibility and bioactivity. However, the addition of Sr2+ ions can decrease bone resorption, while Ba2+ ions can enhance the radiopacity of the prepared mate...

The Robin sequence is a congenital anomaly characterized by a triad of features: micrognathia, glossoptosis, and airway obstruction. This comprehensive historical review maps the evolution of approaches and appliances for its treatment from the past to the current modern possibilities of an interdisciplinary combination of modern engineering, medic...

Robin sequence is a congenital anomaly characterized by a triad of features that include micrognathia, glossoptosis, and airway obstruction. This comprehensive historical review maps the evolution of approaches and appliances for its treatment from the past until current modern possibilities of interdisciplinary combination of modern engineering, m...

This paper explores the impact of Artificial Intelligence (AI) on the role of dental assistants and nurses in orthodontic practices, as there is a gap in understanding the currently evolving impact on orthodontic treatment workflows. The introduction of AI-language models such as ChatGPT 4 is changing patient-office communication and transforming t...

This paper explores the impact of Artificial Intelligence (AI) on the role of dental assistants and nurses in orthodontic practices, as there is a gap in understanding the currently evolving impact on orthodontic treatment workflows. The introduction of AI-language models such as ChatGPT 4 is changing patient-office communication and transforming t...

One in 12 babies is born with a rare genetic disease. Sadly, most cases are undetected until later age, missing time for early treatment and opportunity to prevent complications. Humanity has entered a new era where Big Data collected by governments, including 2D and 3D facial scans, are available. Many rare genetic diseases can be identified by ar...

Citation: Urban, R.; Haluzová, S.; Strunga, M.; Surovková, J.; Lifková, M.; Tomášik, J.; Thurzo, A. AI-Assisted CBCT Data Management in Modern Dental Practice: Benefits, Limitations and Innovations. Abstract: Within the next decade, artificial intelligence (AI) will fundamentally transform the work-flow of modern dental practice. This paper reviews...

This scoping review examines the contemporary applications of advanced artificial intelligence (AI) software in orthodontics, focusing on its potential to improve daily working protocols, but also highlighting its limitations. The aim of the review was to evaluate the accuracy and efficiency of current AI-based systems compared to conventional meth...

In this intellectual work, the clinical and educational aspects of dentistry were confronted with practical applications of artificial intelligence (AI). The aim was to provide an up-to-date overview of the upcoming changes and a brief analysis of the influential advancements in the use of AI in dental education since 2020. In addition, this review...

The biological aspects of determining the dental age of subadults represent an important interdisciplinary scientific link with applications in criminal law and in forensic anthropology and dentistry. In criminal procedural law, it is necessary to determine the exact age of an undocumented person in view of the application of the provisions on juve...

This paper presents a proof-of-concept study on the biocolonization of 3D-printed hydroxyapatite scaffolds with mesenchymal stem cells (MSCs). Three-dimensional (3D) printed biomimetic bone structure made of calcium deficient hydroxyapatite (CDHA) intended as a future bone graft was made from newly developed composite material for FDM printing. The...

This paper presents a proof-of-concept study on the biocolonization of 3D-printed hydroxyapatite scaffolds with mesenchymal stem cells (MSCs). Three-dimensional (3D) printed bio-mimetic bone structure made of Calcium Deficient HydroxyApatite (CDHA) intended as future bone graft was made from newly developed composite material for FDM printing. The...

This paper presents a concept and methodology of biocompatible 3D printing in combination with intraoral and extraoral 3D surface scans for individualized appliances in patients with craniofacial disorders. The concept arises from the clinical problem of rapid growth and minimal compliance of infants with such disorder and the urgency to effectivel...

The current paradigm shift in orthodontic treatment planning is based on facially driven diagnostics. This requires an affordable, convenient, and non-invasive solution for face scanning. Therefore, utilization of smartphones’ TrueDepth sensors is very tempting. TrueDepth refers to front-facing cameras with a dot projector in Apple devices that pro...

The current paradigm shift in orthodontic treatment planning is based on facially driven diagnostics. This requires an affordable, convenient, and non-invasive solution for face scanning. Therefore, utilization of smartphones` TrueDepth sensors is very tempting. TrueDepth refers to front-facing cameras with a dot projector in Apple devices that pro...

This paper introduces a complex novel concept and methodology for the creation of personalized biomedical appliances 3D-printed from certified biocompatible photopolymer resin Dental LT Clear (V2). The explained workflow includes intraoral and CT scanning, patient virtualization, digital appliance design, additive manufacturing, and clinical applic...

This retrospective study evaluated changes in the pharyngeal portion of the upper airway in patients with constricted and normal airways treated with clear aligners (Invisalign, Align). Additionally, we assessed the change of tongue position in the oral cavity from a lateral view. Evaluation was performed with specialized software (Invivo 6.0, Anat...

This retrospective study evaluated changes in the pharyngeal portion of the upper airway in patients with constricted and normal airway treated with clear aligners (Invisalign, Align). Additionally , the paper has assessed the change of tongue position in the oral cavity from lateral view. Evaluation was performed with specialized software (Invivo...

With the arrival of the highly transmissible Omicron variants (BA.4 and BA.5), dentistry faces another seasonal challenge to preserve the biosafety of dental care and education. With the aim of protecting patients, students, teachers and healthcare professionals, this paper introduces a prospective sustainable biosafety setting for everyday dental...

The article focuses on the influence of infill (internal structure of components) in the dimensional accuracy of dental master models during the processes of their fabrication by Fused Deposition Modeling (FDM) technology, and their vacuuming process for production of clear orthodontic aligners. The components, in this case, were the upper jaws (ma...

With arrival of highly transmissible Omicron variants in global pandemic, dentistry is facing another challenge to preserve biosafety of dental care. With a mission to protect both patients and healthcare workers, adaptability to the changing epidemiologic situation is required from dental professionals. This work presents a prospective sustainable...

(1) Teeth, represent in humans the most resilient tissues. However, exposure to concentrated acids might lead to their obliteration, thus making human identification difficult. Teeth often contain dental restorations from materials that are even more resilient to acid impact. This paper introduces novel method of 3D reconstruction of dental pattern...

The publication Orálna a maxilofaciálna chirurgia v kocke was created based on the publication from oral and maxillofacial surgery by Satko, Stanko and team: Oral and Maxillofacial Surgery: Questions and Answers from 1998, which was published on the occasion of the 30th anniversary of the founding of II. Department of Dentistry, Faculty of Medicine...

Omicron variant is more invasive against immunity, but it's not more invasive in any change in degree against masks, and indoor air; than previous variants. With its arrival, dentistry is facing another challenge. With a mission to protect both patients and healthcare workers, we are adapting to the current epidemiologic situation and anticipate th...

(1) Human teeth are the most resilient tissues in the body. However, exposure to concentrated acids might lead to their obliteration, thus making human identification difficult. Teeth often contain dental restorations from materials that are even more resilient to acid impact. This paper introduces novel method of 3D reconstruction of dental patter...

Aim of this research paper is to introduce a novel method of hybrid orthodontic tooth-borne distalizer treatment of class II malocclusion by using 3D printed biocompatible personalized distalizer. Explains 3D designing, printing and clinical application of individualized biocompatible medical device dedicated for orthodontic teeth distalization. Co...

3D interactive atlas of human bones - skeletopedia

Background: Surgical navigation with three-dimensional (3D) printing techniques presents two major advantages: First, from a technical aspect, it facilitates orientation in target anatomical structures resulting in improvement of the accuracy of surgery. Moreover, it shortens the time of complex surgical interventions by preparing the exact positi...

Three-dimensional convolutional neural networks (3D CNN) of artificial intelligence (AI) are potent in image processing and recognition using deep learning to perform generative and descriptive tasks. Compared to its predecessor, the advantage of CNN is that it automatically detects the important features without any human supervision. 3D CNN is us...

Three-dimensional convolutional neural networks (3D CNN) as a type of artificial intelligence (AI) are powerful in image processing and recognition using deep learning to perform generative and descriptive tasks. The advantage of CNN compared to its predecessors is that it automatically detects the important features without any human supervision....

3D printing with biocompatible resins represents new competition to its opposite - subtractive manufacturing, which currently dominates in dentistry. Removing dental material layer-by-layer with lathes, mills or grinders is facing its limits when it comes to fabrication of a detailed complex structures. The aim of this original research was to desi...

ePublished medical book about 3D diagnostics, AI simulations and analyses, and 3D printing in dentistry.. 225 pages with animations

Pod pojmom bio-kompatibilná 3D tlač sa obvykle ro-zumie 3D tlač anorganickými materiálmi, ktoré sú obvykle certifikované a výsledný produkt nenavodzuje nežiadúce reakcie s ľudskými tkanivami. Niekedy si ho študenti pojmovo mýlia s "biotlačou"(bioprintingom) čo je tlač živým materiálom-bunkami. Pri biokompa-tibilnej tlači sa v súčasnosti rozlišujú r...

Background and Objectives: The symptoms of Eagle's syndrome are associated with the elongated styloid process of the temporal bone or calcification of the stylohyoid ligament. The first mention of pain syndrome associated with the elongated styloid process dates back to 1937, when it was described by Watt Weems Eagle. Over the last decade, experts...

Ntroduction: Eagle's syndrome is a rare condition caused by the elongation of the styloid process (> 4 cm) or calcification of the stylohyoid ligament. Patients with Eagle's syndrome typically present various clinical symptoms, such as headache, facial pain, neck pain, pulsating pain, sore throat, foreign body sensation, dysphagia, dysphonia, coug...

Objective The objective of this study was to determine the use of 3D printed model of an eye with intraocular tumor for linear accelerator-based stereotactic radiosurgery. Methods The software for segmentation (3D Slicer) created virtual 3D model of eye globe with tumorous mass based on tissue density from computed tomography and magnetic resonanc...

Nowadays 3D printing allows us to create physical objects on the basis of digital data. Thanks to its rapid development the use enormously increased in medicine too. Its creations facilitate surgical planning processes, education and research in context of organ transplantation, individualization prostheses, breast forms, and others.Our article des...

Despite the advances in surgery, the treatment of large bone defects still represent significant medical problem. In many cases, performance of surgeons is limited by deficiency of transplantable autologous bone grafts. Moreover the harvesting procedure represents additional burden for patient and also increased risk of morbidity and mortality. The...

The aim of our research was to 3D print scaffolds with different porosities from FDA approved nylon 680 using FDM conventional 3D printer and test these scaffolds for cytotoxicity and biocompatibility with human adipose tissue-derived stem cell which underwent osteogenic differentiation in vitro. Standard nylons have been tried in the past. The nyl...

Background: The buccal corridor (negative space) surface displayed in the social smile was outlined by the intersection of the sagittal plane with the most lateral buccal surface of the distal maxillary posterior teeth visible (frequently the premolars) and laterally by the inside of the cheek bordered with the lips. Patients and methods: 300 3D sc...

Objectives: Primary: To evaluate the distribution of soft-tissue asymmetry in population between the age of 20 - 50 years. Secondary: To evaluate which third of the face is affected with asymmetry the most often. Materials and methods: The study was conducted on a sample of randomly selected group of 100 Caucasian individuals (aged 20 - 50 years),...

Background: To measure the accuracy of reproduction between plaster and 3D printed dental models of lower and upper jaw. Material and methods: In this study 14 plaster models of lower and upper jaw of plaster, 14 3D printed dental models of lower and upper jaw of patients and 14 digital scans of lower and upper jaw of patients were measured. The sa...

The specific procedure was invented to create and analyse a virtual reproduction of in-vivo situation of specific anatomy in the region of nose, upper lip and upper incisor midline to achieve proper treatment planning for correction of midline shift and nose asymmetry in the smile. The 3D models were fused in Invivo 5.3/MD studio Anatomage, and gen...

Amelogenesis imperfecta is a set of hereditary defects representing mainly the development defects of enamel without the presence of whole-body symptoms. Developmental disorders can manifest a complete absence of enamel, which is caused by improper differentiation of ameloblasts. This article describes the diagnosis and treatment of a patient with...

Background: To evaluate the accuracy of the three-dimensional printing of cardiovascular structures.To explore whether utilization of three-dimensional printed heart replicas can improve surgical and catheter interventional planning in patients with complex congenital heart defects. Methods: Between December 2014 and November 2015, we fabricated...

The etiology of headache is very diverse; with one of the reasons may be a defect in the function of masticatory muscles. Disharmony in the orofacial system is usually associated with presence of occlusal barrier which leads jaws to the forced position. The result is a change in tension of masseter muscles, their hyperactivity and consequently a si...

Thumb sucking is one of the most common bad habits in childhood. Its prevalence varies between 10 and 34 % in developed countries. In case of long persistence, mainly during the mixed dentition period and high intensity, structures of developing splanchnocranium may be influenced. Thumb sucking is associated with higher prevalence of upper incisor...

In the patient's dental treatment is required cooperation between all branches of dentistry. Therefore it is important to construct a comprehensive treatment plan to achieve the best final effect. At its creation is often involved preservative dentist, prosthodontist, orthodontist, periodontist and surgeon. The need for interdisciplinary cooperatio...

Objectives: The aim of this study was to determine the prevalence and distribution by gender of upper midline diastema in Slovak population in different age. Materials and Methods: 1809 photos of frontal region were collected during an internet campaign realised to establish the standard of teeth hygiene. These photos were screened for upper midlin...

Mouth breathing is a common symptom accompanying diseases in childhood. If it is persisting chronically, it can influence the growth characteristics of developing splanchnocranium. It is associated with narrow maxilla on skeletal and dentoalveolar level and increased face height as a consequence of po-steriorotational growth pattern. In case of ear...

MEFANET Report 03 – Medical teaching with the use of advanced technology MEDICAL E-LEARNING AND TESTING SYSTEM POWERED BY CROWDSOURCING AND BASED ON SOCIAL NETWORKS DESIGNS Thurzo A., Makovník M., Lysý J., Valkovič L., Javorka V. © Masarykova univerzita, 2010 ISSN 1804-2961 ISBN 978-80-210-5302-1 Educational proceedings from the 3rd conference of...

Abstract The recent advancement in the technology brought a few important innovations into clinical dentistry with an impact on the diagnostics and treatment planning, in orthodontics. Many decades the plaster dental model was the only true 3D health record in orthodontics. Today with the possibilities of CBCT diagnostics opens a new perspective an...

To compare the manual and digital cephalometric analyses and to research a new procedure of analog cephalogram digitalization. 40 repeated measurements were used to evaluate the reproducibility and reliability of both methods. The analog x-ray was CHIRALUX2, the digital camera used was Canon PowerShot G5 and the digital tracing was done by Dolphin...

Authors evaluated the effect of the WEB 2.0 environment on dental education and estimated the difference in retention of knowledge by cephalometric analysis in orthodontics between conventional education and off-line e-learning. Five years of experience with complex web-based e-learning system allowed the evaluation by retrospective analysis and on...