Andreas Voss

Andreas Voss
University Medical Center Groningen (UMCG) · Medical Microbiology and Infection Control

MD, PhD

About

569
Publications
90,083
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
18,127
Citations
Citations since 2016
104 Research Items
7021 Citations
201620172018201920202021202202004006008001,0001,200
201620172018201920202021202202004006008001,0001,200
201620172018201920202021202202004006008001,0001,200
201620172018201920202021202202004006008001,0001,200
Additional affiliations
January 2012 - present
January 1997 - present
Radboud University
January 1989 - December 1994
Technische Universität München

Publications

Publications (569)
Article
Background : In Dutch nursing homes, healthcare workers’ attire has been the subject of debate for years. White uniforms and professional white jackets are increasingly being replaced by casual personal attire. Many nursing homes have made this choice because they want to create a homey atmosphere. However, with regard to infection control, casual...
Preprint
Full-text available
Background Coronavirus disease 2019 (COVID-19) has been especially dangerous for elderly people. To reduce the risk of transmission from healthcare workers to elderly people, it is of utmost importance to detect possible severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) positive healthcare workers as early as possible. We aimed to determ...
Article
Full-text available
Emergence of urine-associated Escherichia coli ST38 producing OXA-244 harbouring putative uropathogenicity factors in the Netherlands.
Article
Full-text available
In Dutch: Candida auris is een recent beschreven gist die wereldwijd invasieve infecties en ziekenhuisuitbraken veroorzaakt. Sinds de ontdekking in 2009 zijn er vijf verschillende clades beschreven, verspreid over meer dan 50 landen en alle continenten, behalve Antarctica. C. auris is vaak resistent voor één of meer klassen antifungale middelen en...
Article
Full-text available
In response to the outbreak of SARS-CoV-2, many governments decided in 2020 to impose lockdowns on societies. Although the package of measures that constitute such lockdowns differs between countries, it is a general rule that contact between people, especially in large groups of people, is avoided or prohibited. The main reasoning behind these mea...
Article
Full-text available
Background The Netherlands is currently considered a low endemic country for carbapenem-resistant Enterobacterales (CRE) and carbapenemase-producing Enterobacterales (CPE), experiencing only sporadic hospital outbreaks. This study aims to describe susceptibility to carbapenems and the epidemiology of carbapenemase production in Enterobacterales in...
Article
Full-text available
Objectives The COVID-19 pandemic increases healthcare worker (HCW) absenteeism. The Bacillus Calmette-Guérin (BCG) vaccine may provide non-specific protection against respiratory infections through enhancement of trained immunity. We investigated the impact of BCG vaccination on HCW absenteeism during the COVID-19 pandemic. Methods HCWs exposed to...
Article
Full-text available
Background Hand hygiene is an important measure to prevent healthcare-associated infections in long-term care facilities. Objectives To evaluate compliance with hand hygiene recommendations by different nursing professionals in long-term care facilities and to investigate determinants potentially influencing hand hygiene and whether these differed...
Article
Full-text available
Background Antimicrobial resistance poses a risk for healthcare, both in the community and hospitals. The spread of multidrug-resistant organisms (MDROs) occurs mostly on a local and regional level, following movement of patients, but also occurs across national borders. Aim The aim of this observational study was to determine the prevalence of MD...
Preprint
Full-text available
In response to the outbreak of SARS-CoV-2 many governments decided in 2020 to impose lockdowns. Although the package of measures which constitute such lockdowns differs between countries, it is a general rule that contacts between people, and especially in large groups of people, are avoided or prohibited. The main reasoning behind these measures i...
Article
Full-text available
Verona Integron-encoded Metallo-beta-lactamase (VIM) is the most frequently-encountered carbapenemase in the healthcare-related pathogen Pseudomonas aeruginosa . In the Netherlands, a low-endemic country for antibiotic-resistant bacteria, no national surveillance data on the prevalence of carbapenemase-producing P. aeruginosa (CPPA) was available....
Article
Full-text available
Background Antibiotic resistance requires continuous monitoring by experts to decide whether empiric antibiotic therapies (EAT) should be replaced by alternative antibiotics. The exact moment and criteria for this change is unclear and generally based on consensus between experts. Objectives This scoping review aims to identify from the literature...
Article
Full-text available
Background Carbapenemases produced by Enterobacterales are often encoded by genes on transferable plasmids and represent a major healthcare problem, especially if the plasmids contain additional antibiotic resistance genes. As part of Dutch national surveillance, 50 medical microbiological laboratories submit their Enterobacterales isolates suspect...
Article
Full-text available
Background The emergence of vancomycin resistant enterococci poses a major problem in healthcare settings. Here we describe a hospital-wide outbreak of vancomycin-resistant Enterococcus faecium in a general hospital in The Netherlands in the period December 2014–February 2017. Due to late detection of the outbreak, a large cohort of approximately 2...
Article
Full-text available
Background: During the SARS-CoV-2 pandemic, there was shortage of the standard respiratory protective equipment (RPE). The aim of this study was to develop a procedure to test the performance of alternative RPEs used in the care of COVID-19 patients. Methods: A laboratory-based test was developed to compare RPEs by total inward leakage (TIL). We...
Article
Full-text available
Background Social media may provide a tool, when coupled with a patient-included™ conference, to enhance the engagement among the general public. We describe authors and potential readers of Twitter content surrounding a patient-included™ scientific congress, the International Consortium for Prevention and Infection Control (ICPIC) 2019. Methods R...
Article
Full-text available
Background Elderly residents in long-term care facilities (LTCFs) are vulnerable to healthcare-associated infections. Although hand hygiene is a leading measure for preventing infection, the compliance of healthcare workers is low. The aim of this study is to identify determinants that influence hand hygiene compliance of nursing staff in LTCFs. Th...
Article
Full-text available
Background In long-term care facilities (LTCFs) residents often receive inappropriate antibiotic treatment and infection prevention and control practices are frequently inadequate, thus favouring acquisition of MDR organisms. There is increasing evidence in the literature describing antimicrobial stewardship (AMS) activities in LTCFs, but practical...
Article
Full-text available
Background The JPIAMR ARCH and COMBACTE-MAGNET EPI-Net networks have joined efforts to formulate a set of target actions to link the surveillance of antimicrobial usage (AMU) and antimicrobial resistance (AMR) with antimicrobial stewardship (AMS) activities in four different settings. This White Paper focuses on the veterinary setting and embraces...
Article
Full-text available
Objective Coronavirus disease (COVID-19) was officially declared a pandemic in March 2020. Many cases of COVID-19 are nosocomial, but to the best of our knowledge, no nosocomial outbreaks on psychiatric departments of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been reported in Europe. The different nature of psychiatry makes...
Article
Full-text available
Background: Hand hygiene (HH) is considered one of the most important measures to prevent healthcare-associated infections (HAI). Most studies focus on HH compliance within the hospital setting, whereas little is known for the outpatient setting. The aim of this study was to evaluate compliance with HH recommendations in general practitioners (GPs...
Preprint
Full-text available
Importance: Healthcare workers (HCWs), including those with mild symptoms, may be an important source of COVID-19 within elderly care. Objective: To gain insight into the spread of SARS-CoV-2 among HCWs working in elderly care settings. Design: Cross-sectional study among HCWs working in elderly care in the South-East of the Netherlands, testing fo...
Preprint
Full-text available
Background The emergence of vancomycin resistant enterococci poses a major problem in healthcare settings. Here we describe a hospital-wide outbreak of vancomycin-resistant Enterococcus faecium in a general hospital in The Netherlands in the period December 2014 – February 2017. Due to late detection of the outbreak, a large cohort of approximately...
Preprint
Full-text available
Background We describe the control of a large VRE outbreak in a Dutch general hospital in 2014–2017. Methods After the outbreak was identified, a screening policy consisting of a single rectal swab culture (with enrichment broth) to identify VRE carriage in high risk patients, was implemented. In addition to screening, measures to improve complian...
Article
Full-text available
Antimicrobial stewardship (AMS) is a set of coordinated strategies to improve the use of antimicrobials, to enhance patient outcomes, reduce antimicrobial resistance, and decrease unnecessary costs. The pioneer years of AMS were restricted to high-income countries (HIC), where overconsumption of antibiotics was associated with emergence of multidru...
Preprint
Full-text available
Objectives Implementation of effective infection prevention and control (IPC) measures is needed to support global capacity building to limit transmission of coronavirus disease 2019 (COVID-19) and mitigate its impact on health systems. We assessed the perceptions of healthcare workers on the current global IPC preparedness measures for COVID-19. M...
Article
Objective: Evaluation of a diagnostic algorithm for estimating the risk of COVID-19 in patients who are referred to an emergency department for being suspected of having the disease. Design: Retrospective study. Method: Patients with fever with no apparent cause and patients with recently developed respiratory symptoms, whether or not in combi...
Article
Full-text available
Background Healthcare workers (HCWs) and non-HCWs may contribute to the transmission of influenza-like illness (ILI) to colleagues and susceptible patients by working while sick (presenteeism). The present study aimed to explore the views and behavior of HCWs and non-HCWs towards the phenomenon of working while experiencing ILI. Methods The study...
Article
The current COVID-19 pandemic has led to a worldwide shortage of respiratory protective equipment. In order to offer maximum protection against infection for all healthcare workers, we need to optimise our use of the available equipment. This article provides practical advice on which type of mask is indicated in what specific situation, what requi...
Preprint
Full-text available
Published data were reviewed to find out which temperature and exposure time is necessary for inactivation of coronaviruses. Overall a thermal disinfection at 60°C for 30 min, 65°C for 15 min and 80°C for 1 min was effective to strongly reduce coronavirus infectivity by at least 4 log10.
Preprint
Full-text available
Background Hand hygiene (HH) is considered one of the most important measures to prevent healthcare-associated infections (HAI). Most studies focus on HH compliance within the hospital setting, whereas little is known for the outpatient setting. The aim of this study was to evaluate compliance with HH recommendations in general practitioners (GPs)...
Article
Background: Alcohol based hand rubs (ABHR) are extremely effective at reducing microbial contamination and have an essential role in best practice hand hygiene described by the World Health Organization. Methods: We determined ABHR drying time when performing hand hygiene in a laboratory setting. Which was followed by identifying the amount of A...
Article
Full-text available
Objectives: In 2017 World Health Organization (WHO) published a global priority list of 12 antibiotic-resistant bacteria (ARB) in urgent need of new antibiotics. We aimed to identify and assess publicly-accessible mandatory surveillance systems and outbreaks reporting for these pathogens in the 28 European Union and 4 European Free Trade Associati...
Article
Full-text available
In 2012, the Dutch Working Party for Infection Control (WIP) issued the first Guideline for prevention of transmission of highly-resistant micro-organisms (HRMO) in Hospitals. The next step was to focus on long-term care facilities (LTCFs) both for nursing homes as for small-scale living facilities with nursing home care. These facilities providing...
Article
Full-text available
Antimicrobial stewardship (AMS) and Infection prevention and control (IPC) are two key complementary strategies that combat development and spread of antimicrobial resistance. The ESGAP (ESCMID Study Group for AMS), EUCIC (European Committee on Infection Control) and TAE (Trainee Association of ESCMID) investigated how AMS and IPC activities and tr...
Article
Candida auris (C. auris) is an emerging fungal pathogen causing invasive infections and outbreaks that have been difficult to control in healthcare facilities worldwide. There is a lack of current evidence for pragmatic infection prevention and control recommendations. The aim of this paper was to review the epidemiology of C. auris and identify be...
Article
Background: Use of single-bed rooms for control of extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae is under debate; the added value when applying contact precautions has not been shown. We aimed to assess whether an isolation strategy of contact precautions in a multiple-bed room was non-inferior to a strategy of contact precauti...
Article
Background and purpose: Prosthetic joint infection (PJI) is a serious complication resulting from total knee arthroplasty (TKA) or total hip arthroplasty (THA). In this study, patients with a PJI are compared with patients with an uncomplicated postoperative course to identify relevant risk factors for PJI. Methods: A matched case-control study...
Article
Full-text available
Candida auris is an emerging multidrug resistant infectious yeast which is challenging to eradicate and despite available laboratory methods is still difficult to identify especially in less developed countries. To limit the rapid spread of C. auris, quick and accurate detection is essential. From the perspective of disease surveillance, additional...
Article
Background: Good infection prevention is an important aspect of quality of medical care. The aim was to evaluate infection prevention and control (IPC) performance among Dutch general practitioners (GPs). Methods: Based on the current national IPC guidelines for GPs, a self-administered anonymous online questionnaire was developed and sent to GP...
Article
To the Editor: Eyre et al. (Oct. 4 issue)1 report finding that reusable skin-surface axillary temperature probes were the source of a Candida auris outbreak in a U.K. intensive care unit. Yeasts persisted on the equipment despite cleaning with wipes containing quaternary ammonium compounds, a procedure that deviated from the manufacturer’s instruct...
Article
Full-text available
Importance: Resistance of gram-negative bacilli to carbapenems is rapidly emerging worldwide. In 2016, the World Health Organization defined the hospital-built environment as a core component of infection prevention and control programs. The hospital-built environment has recently been reported as a source for outbreaks and sporadic transmission e...
Article
Full-text available
Background: Candida auris is a globally emerging yeast, causing severe infections in patients with underlying diseases. This yeast is responsible for several outbreaks within healthcare facilities, where it can be found on hospital surfaces and patient care devices. Spread from these fomites may be prevented by improving the decontamination of hosp...
Article
Full-text available
Background: Candida auris is an emerging multidrug resistant infectious yeast which is challenging to eradicate and despite available laboratory methods, is still difficult to identify especially in less developed countries. To limit the rapid spread of C. auris, quick and accurate detection is essential. From the perspective of disease surveillanc...
Article
Full-text available
Abstract Background: Endoscopy related infections represent an important threat for healthcare systems worldwide. Recentoutbreaks of infections with multidrug resistant micro-organisms have highlighted the problems of contaminatedendoscopes. Endoscopes at highest risk for contamination have intricate mechanisms, multiple internal channelsand narrow...
Article
Full-text available
Keeping hospitals clean is a crucial patient safety issue. The importance of the hospital environment in patient care has only recently been recognized widely in infection prevention and control (IPC). In order to create a movement for change, a group of international infection control experts teamed up with Interclean, the largest cleaning trade-s...
Article
Staphylococcus aureus remains one of the dominant pathogens in infective endocarditis (IE) causing 25% to 30% of all cases [1,2] including healthcare-associated IE which comprises about 30% of IE [3]. Most IE involve the aortic or mitral valves, with tricuspid valve involvement accounting for fewer than 10% of cases, often in association with injec...
Article
Full-text available
Objectives: Although testing of antimicrobial agents for susceptibility has inherent variability like any assay, it is generally held that there are also real differences in susceptibility between strains. In the routine laboratory, variability of the MIC measurement may be sufficient to mask real strain differences. We determined which factors co...
Article
Following the first point prevalence study in Dutch nursing homes conducted each November from 2007 to 2009, we conducted a follow-up point prevalence study of healthcare-associated infections (HAIs) each November from 2010 to 2017. Similar methods and criteria were used. Resident characteristics were recorded, data collection was performed by the...
Article
Purpose of review: To give an update on the recent emergence of Candida auris. Recent findings: C. auris is a pathogen, that evades present therapeutic options, that is highly virulent, causes disease in all types of patients, and spreads easily in the environment and among patients, thereby posing an imminent threat to our patients. The fact th...
Article
Full-text available
Background Despite many preventive measures, outbreaks with multi-drug resistant micro-organisms (MDROs) still occur. Moreover, current alert systems from healthcare organizations have shortcomings due to delayed or incomplete notifications, which may amplify the spread of MDROs by introducing infected patients into a new healthcare setting and ins...
Article
Full-text available
Background: Antimicrobial resistance has become an urgent global health priority. Basic hygiene practices and cleaning and disinfection of the hospital environment are key in preventing pathogen cross-transmission. Aim: To our knowledge no studies have assessed the worldwide differences in cleaning and disinfection practices in healthcare facili...
Article
Panton–Valentine leukocidin (PVL), a pore-forming cytotoxic secreted toxin, has been associated with severe Staphylococcus aureus pneumonia and prototypical skin lesions. The reported incidence and prevalence of PVL-positive S. aureus (PVLP-SA) varies globally and suffers from a selective reporting bias towards communityassociated methicillin-resis...
Article
Full-text available
Panton Valentine Leucocidin (PVL), a pore-forming cytotoxic secreted toxin, has been associated with severe Staphylococcus aureus pneumonia and prototypical skin lesions. The reported incidence and prevalence of PVL-positive S. aureus (PVLPSA) varies globally and suffers from a selective reporting bias towards community associated MRSA (CA-MRSA). R...
Article
Full-text available
Background Infections with carbapenem-resistant Enterobacteriaceae (CRE) are increasingly being reported from patients in healthcare settings. They are associated with high patient morbidity, attributable mortality and hospital costs. Patients who are “at-risk” may be carriers of these multidrug-resistant Enterobacteriaceae (MDR-E). The purpose of...