Andreas Lehmann

Andreas Lehmann
Merck KGaA · CoE Biopharmaceutics

Pharmacist
Merck Healthcare KGaA

About

9
Publications
2,596
Reads
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55
Citations
Citations since 2017
6 Research Items
55 Citations
201720182019202020212022202302468101214
201720182019202020212022202302468101214
201720182019202020212022202302468101214
201720182019202020212022202302468101214

Publications

Publications (9)
Article
Counterfeit drugs can hurt patients and harm the pharmaceutical industry. In 2006, the International Medical Products Anti-Counterfeiting Taskforce expressed a need to generate more and better data to calculate a worldwide prevalence of counterfeiting. This review analyzes field test data that were published in the time-frame January 2007 to Decemb...
Article
To assess drug quality and pharmaceutical care in South Africa, "mystery" (i.e. anonymous) customers collected 316 samples from July to September 2016. Solid dosage forms containing amoxicillin alone or in combination with clavulanic acid as well as analgesics containing paracetamol alone or in combination were sampled in a randomized fashion from...
Article
Objectives To examine differences in drug product quality between products marketed in developed countries and in developing countries. Methods The quality of drug products marketed in both Germany and South Africa by the same pharmaceutical company was compared. A fixed‐dose combination tablet containing amoxicillin/clavulanic acid, and mometason...
Article
In vitro precipitation assays are often applied to support drug and formulation development. Current methods applied to quantify the amount of dissolved drug, in particular (U)HPLC, require time-consuming sample preparation. Furthermore, small precipitates formed during the nucleation phase may not be removed quantitatively by filtration or centrif...
Article
Biopharmaceutical precipitation assays are an important in vitro tool to characterize the precipitation behavior of weakly basic drugs during their transit from the stomach into the small intestine. To mimic the intestinal fluids more closely, biorelevant media like Fasted State Simulated Intestinal Fluid (FaSSIF) and versions thereof are often app...
Article
Biorelevant solubility and dissolution testing is an important tool during pharmaceutical development, however, solubility experiments performed using biorelevant media often do not properly match the solubility data observed in human intestinal fluids. Even though the bicarbonate buffer is the predominant buffer system in the small intestine, in v...
Article
Hair loss as well as excessive sweating is an unpleasant symptom for patients. Furthermore, both scenarios are difficult for counseling in daily pharmaceutical practice. Hair loss can have different causes and occurrences: diffuse alopecia, androgenetic alopecia and alopecia areata. For the treatment of androgenetic alopecia, active substances like...

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