Andreas BorchelUniversity of Bergen | UiB · Department of Biological Science
Andreas Borchel
PhD
About
19
Publications
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Introduction
Andreas Borchel currently works at the Department of Biology, University of Bergen. Andreas does research in Genetics and Molecular Biology.
Publications
Publications (19)
Salmon lice are ectoparasites on salmonids and feed on blood, mucus, and skin from their hosts. This causes high annual costs for treatment and control for the aquaculture industry. Salmon lice have a life cycle consisting of eight life stages. Sex determination by eye is only possible from the sixth stage onwards. A molecular sex determination has...
Salmon lice (Lepeophtheirus salmonis) are marine parasitic copepods living on salmonids and are challenging for salmon aquaculture. One of several treatment methods is the application of freshwater to the fish which can lead to lice loss. However, lab experiments have shown that salmon lice, acclimated to seawater, are capable of surviving for seve...
The objective of the present study is to identify and evaluate informative indicators for the welfare of rainbow trout exposed to (A) a water temperature of 27 °C and (B) a stocking density of 100 kg/m3 combined with a temperature of 27 °C. The spleen-somatic and condition index, haematocrit and the concentrations of haemoglobin, plasma cortisol an...
The salmon louse Lepeophtheirus salmonis is a parasite of Atlantic salmon and other salmonids. Every year, it causes high costs for the Norwegian aquaculture industry. While the morphology of the female genital tract has been described, knowledge of the molecular basis of reproduction is very limited. We identified nine genes which are expressed ex...
Apoptosis is an integral part of homeostasis and supports multiple physiological processes such as development and immune defense, thereby directly targeting damaged or unwanted cells without affecting neighbor cells. In the present study, we characterized the apoptotic key factors caspase-3, −7, and − 8 as well as regulator protein TPT1 (translati...
The creatine/phosphocreatine system is the principal energy buffer in mammals, but is scarcely documented in fish. We measured the gene expression of major enzymes of this system, glycine amidinotransferase (GATM), guanidinoacetate N-methyltransferase (GAMT) and muscle-type creatine kinase (CKM) in kidney, liver, and muscle tissues of fish and mamm...
The salmon louse (Lepeophtheirus salmonis) is an important parasite of Atlantic salmon (Salmo salar). It is widely spread in aquaculture facilities and leads to economic losses every year. As it has developed resistances against many common treatments, new control methods must be established. Here we characterize a novel gene family of the salmon l...
A rapid decline in temperature poses a major challenge for poikilothermic fish, as their entire metabolism depends on ambient temperature. The gene expression of rainbow trout Oncorhynchus mykiss having undergone such a cold shock (\(0{^{\circ }}\hbox {C}\)) was compared to a control (\(5{^{\circ }}\hbox {C}\)) in a microarray and quantitative real...
Salmon lice (Lepeophtheirus salmonis) are parasitic copepods, living mainly on Atlantic salmon and leading to large economical losses in aquaculture every year. Due to the emergence of resistances to several drugs, alternative treatments are developed, including treatment with hydrogen peroxide, freshwater or thermal treatment. The present study gi...
Stocking density is considered as a key factor determining the productivity of fish aquaculture systems. The transcriptomic response to crowding stress is, however, still poorly investigated. We aimed to identify potential biomarker genes via microarray analyses to gain insight into molecular pathways modulated by density-induced stress in farmed r...
Maraena whitefish (Coregonus maraena, Bloch, 1779) is a high-quality food fish belonging to the family Salmonidae with considerable economic relevance in the Baltic area. Aquaculture of this species is fundamental for its successful conservation and thus sustainable fisheries. Robust fishes obtained from breeding lines build the basis for effective...
Seasonal water temperatures can be stressful for fish in aquaculture and can therefore negatively influence their welfare. Although the kidney is the crucial organ associated with the primary stress response, knowledge about the stress-modulated kidney transcriptome in salmonids is limited. In the present study, we used a comparative microarray app...
Interleukin-6 (IL6) is a pleiotropic cytokine with important immunoregulatory functions. Its expression is inducible in immune cells and tissues of several fish species. We also found that IL6 mRNA abundance was significantly increased in spleen, liver, and gill of rainbow trout after experimental infection with Aeromonas salmonicida. Genomic DNA s...
Creatine plays an important role in the cell as an energy buffer. As the energy system is a basic element of the organism it may possibly contribute to differences between rainbow trout strains selected for the traits growth and robustness, respectively. The cDNA sequences of creatine-related genes encoding glycine amidinotransferase (GATM), guanid...
Robustness is a sparsely observed trait in rainbow trout aquaculture; however, the different stress adaptation potential of fish and its commercial relevance is undervalued. Compared with other economical traits, such as growth or body weight, characterization of robustness and specific statements about the trait are very complex. Therefore, trait...
Projects
Projects (2)
Development of robust regional aquaculture fish breeds:
- Molecular characterization of stress and immune response
- Phenotype analyses - production results
1. Rainbow trout (strain BORN) - genetic determination of robustness
2. Coregonus maraena (Baltic form) - from wildtype to aquaculture
3. Pike perch - family based selection studies
Our research is focused on the analysis of molecular biological effects of combined environmental stressors on growth and immune defense in locally farmed fish (e.g. pikeperch, rainbow trout, maraena whitefish). In a genome wide approach, we compare functional diversity and gene regulation in fish under different breeding conditions. Results contribute to understand the adaptation potential of fishes. Molecular fish welfare indicators conduct to develop facile diagnostic tests well-functioning in practical fish aquaculture.
