Andrea Tricco

Andrea Tricco
St. Michael's Hospital | SMH · Knowledge Translation

PhD, MSc

About

455
Publications
138,381
Reads
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53,117
Citations
Citations since 2017
286 Research Items
49553 Citations
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Introduction
Andrea Tricco currently works at the Knowledge Translation, St. Michael's Hospital. Andrea does research in General Practice, Clinical Trials and Epidemiology. Their current project is 'Ongoing scoping reviews '.
Additional affiliations
June 2014 - present
University of Toronto
Position
  • Professor
September 2011 - present
St. Michael's Hospital
Position
  • Researcher
September 2011 - present
BMC Medical Research Methodology
Position
  • Associate Editor
Education
September 2005 - October 2009
University of Ottawa
Field of study
  • Population Health
September 2002 - November 2004
University of Toronto
Field of study
  • Epidemiology
September 1998 - June 2002
The University of Western Ontario
Field of study
  • Health Science

Publications

Publications (455)
Article
Full-text available
A declaração dos Principais Itens para Relatar Revisões Sistemáticas e Meta-análises (PRISMA), publicada em 2009, foi desenvolvida para ajudar revisores sistemáticos a relatar de forma transparente por que a revisão foi feita, os métodos empregados e o que os autores encontraram. Na última década, os avanços na metodologia e terminologia de revisõe...
Preprint
Full-text available
Background Systematic reviews (SRs) are being published at an accelerated rate. Decision makers are often faced with the challenge of comparing and choosing between multiple SRs on the same topic. We surveyed individuals in the healthcare field to understand what criteria they use to compare and select one or more SRs from multiple on the same topi...
Article
Objectives Individual participant data (IPD) from randomised controlled trials (RCTs) can be used in network meta-analysis (NMA) to underpin patient care and are the best analyses to support the development of guidelines about the use of healthcare interventions for a specific condition. However, barriers to IPD retrieval pose a major threat. The a...
Article
Full-text available
Background Due to the explosion in rapid reviews in the literature during COVID-19, their utility in universal health coverage and in other routine situations, there is now a need to document and further advance the application of rapid review methods, particularly in low-resource settings where a scarcity of resources may preclude the production o...
Article
Full-text available
Well-conducted systematic reviews and other evidence syntheses are important in informing policy and practice decisions. It is reasonable to expect that the processes by which reviews are planned, conducted, analysed and reported are informed by up-to-date research evidence. However, many of the decisions taken when ‘doing’ systematic reviews and o...
Article
Full-text available
Objective To examine the comparative efficacy and complications of long-acting and intermediate-acting insulin for different patient characteristics for type 1 diabetes mellitus (T1DM). Design Systematic review and individual patient data (IPD) network meta-analysis (NMA). Data sources MEDLINE, EMBASE and the Cochrane Central Register of Controll...
Article
Objectives To identify the similarities and differences in data-sharing policies for clinical trial data that are endorsed by biomedical journals, funding agencies, and other professional organizations. Additionally, to determine the beliefs, and opinions regarding data-sharing policies for clinical trials discussed in articles published in biomedi...
Article
Full-text available
Background Falls are a leading cause of injury-related hospitalizations among adults aged 65 years and older and may result in social isolation. Objective To summarise evidence on falls and subsequent social isolation and/or loneliness in older adults through a scoping review. Eligibility criteria Studies were eligible for inclusion if the popula...
Conference Paper
Objectives The synthesis of individual patient data (IPD) from randomised clinical trials (RCTs) can strengthen evidence used for decision-making. Network meta-analyses (NMA) modelling IPD usually include non-sponsored or publicly sponsored RCTs. Evidence suggests that IPD sharing may depend on study characteristics, such as funding type, RCT size,...
Conference Paper
Objectives Alzheimer’s dementia (AD) is the most common type of dementia. However, it is unclear which cognitive enhancer is optimal for severe AD. Patient-level data from people with AD can be helpful to explore patient-level variation per treatment response. Pooling individual patient data (IPD) from multiple randomised clinical trials (RCTs) of...
Article
Scoping reviewers often face challenges in the extraction, analysis, and presentation of scoping review results. Using best-practice examples and drawing on the expertise of the JBI Scoping Review Methodology Group and an editor of a journal that publishes scoping reviews, this paper expands on existing JBI scoping review guidance. The aim of this...
Article
Absract Objective Scoping reviews and evidence map methodologies are increasingly being used by researchers. The objective of this article is to examine how scoping reviews can reduce research waste. Study design and setting This article summarises the key issues facing the research community regarding research waste and how scoping reviews can m...
Preprint
Full-text available
Introduction: Network meta-analyses (NMAs) have gained popularity and grown in number due to their ability to provide estimates of comparative effectiveness of multiple treatments for the same condition. The aim of this study is to conduct a methodological review to compile a preliminary list of concepts related to bias in NMAs. Methods and Analysi...
Article
Full-text available
Background Network meta-analysis (NMA) is increasingly used in guideline development and other aspects of evidence-based decision-making. We aimed to develop a risk of bias (RoB) tool to assess NMAs (RoB NMA tool). An international steering committee recommended that the RoB NMA tool to be used in combination with the Risk of Bias in Systematic rev...
Article
Objective: The objective of this scoping review was to explore how absorptive capacity has been conceptualized and measured in studies of innovation adoption in health care organizations. Introduction: Current literature highlights the need to incorporate knowledge translation processes at the organizational and system level to enhance the adopt...
Article
Full-text available
Objective To develop a reporting guideline for overviews of reviews of healthcare interventions. Design Development of the preferred reporting items for overviews of reviews (PRIOR) statement. Participants Core team (seven individuals) led day-to-day operations, and an expert advisory group (three individuals) provided methodological advice. A pa...
Article
Full-text available
Objectives: A rapid review is a form of evidence synthesis considered a resource-efficient alternative to the conventional systematic review. Despite a dramatic rise in the number of rapid reviews commissioned and conducted in response to the coronavirus disease 2019 pandemic, published evidence on the optimal methods of planning, doing, and shari...
Article
Objective: The objective of this scoping review is to identify evidence synthesis types and previously proposed classification systems, typologies, or taxonomies that have guided evidence synthesis. Introduction: Evidence synthesis is a constantly evolving field. There is now a plethora of evidence synthesis approaches used across many different...
Article
Objective: We provide guidance for considering equity in rapid reviews through examples of published COVID-19 rapid reviews. Study design and setting: This guidance was developed based on a series of methodological meetings, review of internationally renowned guidance such as the Cochrane Handbook and the Preferred Reporting Items for Systematic...
Conference Paper
Objectives Alzheimer’s dementia (AD) is the most common type of dementia. However, it is unclear which cognitive enhancer is optimal for severe AD. Patient-level data from people with AD can be helpful to explore patient-level variation per treatment response. Pooling individual patient data (IPD) from multiple randomised clinical trials (RCTs) of...
Conference Paper
Objectives The synthesis of individual patient data (IPD) from randomised clinical trials (RCTs) can strengthen evidence used for decision-making. Network meta-analyses (NMA) modelling IPD usually include non-sponsored or publicly sponsored RCTs. Evidence suggests that IPD sharing may depend on study characteristics, such as funding type, RCT size,...
Article
Full-text available
Introduction Despite growing evidence, uncertainty persists about which frailty assessment tools are best suited for routine perioperative care. We aim to understand which frailty assessment tools perform well and are feasible to implement. Methods and analysis Using a registered protocol following Preferred Reporting Items for Systematic Reviews...
Article
Full-text available
Introduction: Lack of standardised clinical data collection may lead to reduced quality in musculoskeletal (MSK)-related clinical care and research. Little is known about the availability and characteristics of minimal clinical data sets for spine-related MSK disorders in primary care and outpatient settings and their utility for improving healthc...
Article
Full-text available
Introduction Sepsis is a common, life-threatening syndrome of physiologic, pathologic, and biochemical abnormalities that are caused by infection and propagated by a dysregulated immune response. In 2017, the estimated annual incidence of sepsis around the world was 508 cases per 100,000 (95% confidence interval [CI], 422–612 cases per 100,000), ho...
Article
Full-text available
Background Systematic reviews of outcome measurement instruments are important tools in the evidence-based selection of these instruments. COSMIN (COnsensus-based Standards for the selection of health Measurement INstruments) has developed a comprehensive and widespread guideline to conduct systematic reviews of outcome measurement instruments, but...
Article
Objectives Older adults are at high risk of influenza-related complications or hospitalization. The purpose of this systematic review is to assess the relative cost-effectiveness of all influenza vaccine options for older adults. Methods This systematic review identified economic evaluation studies assessing the cost-effectiveness of influenza vac...
Article
Full-text available
Objectives The COVID-19 pandemic has stimulated growing research on treatment options. We aim to provide an overview of the characteristics of studies evaluating COVID-19 treatment. Design Rapid scoping review Data sources Medline, Embase and biorxiv/medrxiv from inception to 15 May 2021. Setting Hospital and community care. Participants COVID-...
Article
Full-text available
Background Older adults experience symptoms of depression, leading to suffering and increased morbidity and mortality. Although we have effective depression therapies, physical distancing and other public health measures have severely limited access to in-person interventions. Objective To describe the efficacy of virtual interventions for reducin...
Article
Full-text available
Objective : To evaluate the reporting of authors’ justifications for choosing the scoping review methodology in oral health. Study selection, data and source : This is a meta-research study about scoping reviews in dentistry. This study searched for reviews in PubMed and Scopus without year restrictions and restricted to English-language publicati...
Article
In 2009, the Canadian Institutes of Health Research, Health Canada, and other stakeholders established the Drug Safety and Effectiveness Network (DSEN) to address the paucity of information on drug safety and effectiveness in real-world settings. This unique network invited knowledge users (e.g., policy makers) to submit queries to be answered by r...
Article
Full-text available
Objective: To examine the comparative efficacy and safety of cognitive enhancers by patient characteristics for managing Alzheimer's dementia (AD). Design: Systematic review and individual patient data (IPD) network meta-analysis (NMA) based on our previously published systematic review and aggregate data NMA. Data sources: MEDLINE, Embase, Co...
Article
Full-text available
Background As of November 25th 2021, four SARS-CoV − 2 variants of concern (VOC: Alpha (B.1.1.7), Beta (B.1.351), Gamma (P.1), and Delta (B.1.617.2)) have been detected. Variable degrees of increased transmissibility of the VOC have been documented, with potential implications for hospital and health system capacity and control measures. This rapid...
Article
Full-text available
Objectives: To identify, critically appraise and summarise evidence on the impact of employing primary healthcare professionals (PHCPs: family physicians/general practitioners (GPs), nurse practitioners (NP) and nurses with increased authority) in the emergency department (ED) triage, on patient flow outcomes. Methods: We searched Medline (Ovid)...
Article
Full-text available
Introduction: An increasing growth of systematic reviews (SRs) presents notable challenges for decision-makers seeking to answer clinical questions. In 1997, an algorithm was created by Jadad to assess discordance in results across SRs on the same question. Our study aims to (1) replicate assessments done in a sample of studies using the Jadad alg...
Article
Knowledge user consultation is often limited or omitted in the conduct of scoping reviews. Not including knowledge users within the conduct and reporting of scoping reviews could be due to a lack of guidance or understanding about what consultation requires and the subsequent benefits. Knowledge user engagement in evidence synthesis, including cons...
Preprint
Full-text available
The publication of systematic reviews has rapidly increased making it challenging to remain apprised of and interpret evidence from their growing number. A newer form of evidence synthesis, overview of reviews, synthesizes evidence from multiple systematic reviews. Authors would benefit from evidence- and consensus-based guidance for the complete a...
Preprint
The Preferred Reporting Items for Overviews of Reviews (PRIOR) statement provides an evidence-based reporting guideline developed using established, rigorous methods that involved a four-stage process (project launch, evidence reviews, modified Delphi exercise, development of the reporting guideline) and an international stakeholder group represent...
Article
Full-text available
Evidence synthesis encompasses a broad range of review types, and scoping reviews are an increasingly popular approach to synthesizing evidence in a number of fields. They sit alongside other evidence synthesis methodologies, such as systematic reviews, qualitative evidence synthesis, realist synthesis, and many more. Until now, scoping reviews hav...
Article
Full-text available
Objectives The objective of our systematic review was to identify the effective interventions to prevent or mitigate social isolation and/or loneliness in older adults who experienced a fall. Design Systematic review. Data sources MEDLINE, Embase, the Cochrane Central Register of Controlled Trials and Ageline were searched (from inception to Febr...
Article
Full-text available
Canada has made great progress in synthesizing, disseminating, and integrating research findings into health systems and clinical decision-making; yet gaps exist in the research-to-practice continuum. The Strategy for Patient-Oriented Research (SPOR) Evidence Alliance aims to help close gaps by providing decision-makers with evidence that is timely...
Article
Objective To develop a web-based decision support tool that guides users through a series of simple questions for recommending knowledge synthesis methods suitable for their research question. Study design and setting We used findings from previous work to structure a set of questions along key dimensions of different knowledge synthesis methods....
Article
Objectives The incidence of type 1 diabetes mellitus is increasing every year requiring substantial expenditure on treatment and complications. A systematic review was conducted on the cost-effectiveness of insulin formulations, including ultralong-, long-, or intermediate-acting insulin, and their biosimilar insulin equivalents. Methods MEDLINE,...
Article
Full-text available
Background The demand for peer reviewers is often perceived as disproportionate to the supply and availability of reviewers. Considering characteristics associated with peer review behaviour can allow for the development of solutions to manage the growing demand for peer reviewers. The objective of this research was to compare characteristics among...
Preprint
Full-text available
Objective: We provide guidance for considering equity in rapid reviews through examples of published COVID-19 rapid reviews. Study design and setting: This guidance was developed based on a series of methodological meetings, review of internationally renowned guidance such as the Cochrane Handbook and the Preferred Reporting Items for Systematic Re...
Article
Full-text available
The demand for rapid reviews has exploded in recent years. A rapid review is an approach to evidence synthesis that provides timely information to decision-makers (eg, health care planners, providers, policymakers, and patients) by simplifying the evidence synthesis process. A rapid review is particularly appealing for urgent decisions.JBI is a wor...
Preprint
Full-text available
Introduction: Network meta-analysis (NMA) is increasingly used in guideline development and other aspects of evidence-based decision-making. We engaged with stakeholders in early phases of the development of a new tool to assess risk of bias (RoB) in NMA to facilitate its later use and potentially widen its impact. Methods: We surveyed stakeholders...
Article
Full-text available
Objective: The purpose of this article is to clearly describe how to develop a robust and detailed scoping review protocol, which is the first stage of the scoping review process. This paper provides detailed guidance and a checklist for prospective authors to ensure that their protocols adequately inform both the conduct of the ensuing review and...
Article
We assessed the joint effects of back pain and mental health conditions on healthcare utilization and costs in a population-based sample of Ontario adults. We included Ontario adult respondents of Canadian Community Health Survey between 2003-2012, followed to 2018 by linking survey data to administrative databases. Joint exposures were self-report...
Article
Systematic reviews with network meta-analysis that ignore potential dose effects could limit the applicability and validity of review findings. This article aims to help content experts (eg, clinicians), methodologists, and statisticians better understand how to incorporate dose effects in network meta-analysis. Three models are described that make...
Chapter
The following chapter highlights the methodological similarities/differences and strengths/weaknesses between systematic reviews and two common alternative approaches for knowledge synthesis: rapid reviews and scoping reviews. In doing so, the intention is to provide readers with guidance in determining whether a rapid or scoping review may be more...
Article
This is the introductory paper in a collection of four papers on the Strategy for Patient-Oriented Research (SPOR) Evidence Alliance, a pan-Canadian research initiative that was funded by the Canadian Institutes of Health Research in September of 2017. Here, we introduce the SPOR enterprise in Canada, provide a rationale for the creation of the SPO...
Article
Full-text available
Background Systematic reviews are the cornerstone of evidence-based medicine. However, systematic reviews are time consuming and there is growing demand to produce evidence more quickly, while maintaining robust methods. In recent years, artificial intelligence and active-machine learning (AML) have been implemented into several SR software applica...
Article
Full-text available
Background The comparative safety and efficacy between anti-vascular endothelial growth factor agents (anti-VEGFs) and between combined therapies for patients with neovascular age-related macular degeneration (nAMD) is unclear. We conducted a systematic review to examine the comparative safety and efficacy anti-VEGFs for adults with nAMD. Methods...
Preprint
Full-text available
Introduction: The exponential growth of published SRs (SRs) presents challenges for clinicians seeking to answer clinical questions. In 1997, an algorithm was created by Jadad et al. to choose the best SR across multiple but similar SRs with conflicting results. Our study aims to replicate assessments done by authors using the Jadad algorithm to de...
Preprint
Full-text available
Introduction: The exponential growth of published systematic reviews (SRs) presents challenges for clinicians seeking to answer clinical questions. In 1997, an algorithm was created by Jadad et al. to choose the best SR across multiple. Our study aims to replicate author assessments using the Jadad algorithm to determine: (i) if we chose the same S...
Article
Full-text available
Objectives The four SARS-CoV-2 variants of concern (VOC; Alpha, Beta, Gamma and Delta) identified by May 2021 are highly transmissible, yet little is known about their impact on public health measures. We aimed to synthesise evidence related to public health measures and VOC. Design A rapid scoping review. Data sources On 11 May 2021, seven datab...
Article
Uvod: Preporučene smjernice za izvještavanje u sustavnim pregledima i metaanalizama (engl. Preferred Reporting Items for Systematic reviews and Meta-Analyses, PRISMA) prvi su put objavljene 2009. godine kako bi autorima sustavnih pregleda omogućile transparentno izvještavanje o predmetu istraživanja, korištenim metodama i dobivenim rezultatima. Tij...
Article
Full-text available
Background: The value of rapid reviews in informing health care decisions is more evident since the onset of the coronavirus disease 2019 (COVID-19) pandemic. While systematic reviews can be completed rapidly, rapid reviews are usually a type of evidence synthesis in which components of the systematic review process may be simplified or omitted to...
Article
Background: Studies of people who inject drugs (PWID) commonly use questionnaires to determine whether participants are currently, or have recently been, on opioid agonist treatment for opioid use disorder. However, these previously unvalidated self-reported treatment measures may be susceptible to inaccurate reporting. Methods: We linked baseli...
Article
Full-text available
Objectives To summarise the current evidence regarding interventions for accurate and timely cancer diagnosis among symptomatic individuals. Design A scoping review following the Joanna Briggs Institute’s methodological framework for the conduct of scoping reviews and reported in accordance with the Preferred Reporting Items for Systematic Reviews...
Article
Full-text available
Introduction: Considerable observational evidence suggests that cancer online support groups reduce feelings of isolation, depression and anxiety, enhance coping and self-management, and lead to better informed patients. Other studies indicate that cancer online support groups can increase distress. Yet no studies theorise the complex, context-dep...
Article
Full-text available
What is known and Objective Scoping reviews are a valuable evidence synthesis methodology. They can be used to map the evidence related to any topic to allow examination of practice, methods, policy and where (and how) future research could be undertaken. As such, they are a useful form of evidence synthesis for pharmacy clinicians, researchers and...
Article
Full-text available
Scoping reviews are an increasingly common approach to evidence synthesis with a growing suite of methodological guidance and resources to assist review authors with their planning, conduct and reporting. The latest guidance for scoping reviews includes the JBI methodology and the Preferred Reporting Items for Systematic Reviews and Meta-Analyses—E...
Preprint
Full-text available
Introduction: An increasing growth of systematic reviews (SRs) presents notable challenges for decision-makers seeking to answer clinical questions. Overviews of systematic reviews aim to address these challenges by summarising results of SRs and making sense of potentially discrepant SR results and conclusions. In 1997, an algorithm was created by...
Preprint
Full-text available
Introduction: An increasing growth of systematic reviews (SRs) presents notable challenges for decision-makers seeking to answer clinical questions. In 1997, an algorithm was created by Jadad to assess discordance in results across SRs on the same question. Our study aims to (a) replicate assessments done in a sample of studies using the Jadad algo...