Andrea McKavanagh

Andrea McKavanagh
University of Liverpool | UoL · Institute of Translational Medicine

BSc MRes

About

5
Publications
433
Reads
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12
Citations
Citations since 2016
5 Research Items
12 Citations
201620172018201920202021202202468
201620172018201920202021202202468
201620172018201920202021202202468
201620172018201920202021202202468
Additional affiliations
September 2018 - present
University of Liverpool
Position
  • PhD Student
September 2017 - September 2018
Medimmune UK
Position
  • Research Associate
Education
September 2015 - September 2016
University of Liverpool
Field of study
  • Biomedical Science and Translational Medicine
September 2012 - September 2015
Liverpool John Moores University
Field of study
  • Biomedical Science

Publications

Publications (5)
Preprint
Background: Previous neuroimaging studies reported functional and structural impairments of the upper basal ganglia (specifically, the striatum) in idiopathic generalised epilepsy (IGE). However, these studies often overlook lower basal ganglia structures located in and adjacent to the midbrain due to poor contrast on clinically acquired volumetric...
Article
Background: Idiopathic generalised epilepsy (IGE) is a collection of generalised non-lesional epileptic network disorders. Around 20-40% of patients with IGE are refractory to anti-seizure medication and mechanisms underlying refractoriness are poorly understood. Here, we characterise structural brain network alterations and determine whether netw...
Article
Full-text available
Despite an increasing number of drug treatment options for people with idiopathic generalized epilepsy (IGE), drug resistance remains a significant issue and the mechanisms underlying it remain poorly understood. Previous studies have largely focused on potential cellular or genetic explanations for drug resistance. However, epilepsy is understood...
Article
Full-text available
Despite an expanding literature on brain alterations in patients with longstanding epilepsy, few neuroimaging studies investigate patients with newly diagnosed focal epilepsy (NDfE). Understanding brain network impairments at diagnosis is necessary to elucidate whether or not brain abnormalities are principally due to the chronicity of the disorder...
Poster
Full-text available
Study objectives: To identify structural network changes in patients with non-lesional newly diagnosed focal epilepsy (NDfE) and determine the relationship to seizure outcomes two years after diagnosis. Methods: • Participants 29 controls and 27 patients with NDfE • MRI acquisition T1-/T2-weighted (T1w/T2w) MRI; 60-dir multi-shell dMRI MRI analysi...

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Projects

Projects (2)
Project
The objective of this project is to characterize brain structural and functional connectivity in patients with epilepsy through advanced MRI-analysis techniques.