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Introduction
Me interesa realizar investigación en el área neonatal, con enfoque en el área de las neurociencias. Nos propusimos estudiar el ciclo sueño-vigilia en los recién nacidos prematuros y sus cambios con la edad gestacional. Actualmente estoy estudiando los efectos de la cafeína sobre el sueño en los prematuros, mediante polisomnografía. Nos interesa medir el efecto de la cafeína a través del análisis cuantitativo del EEG.
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Publications (9)
The dorsal (DRN) and median (MRN) raphe are important nuclei involved in similar functions, including mood and sleep, but playing distinct roles. These nuclei have a different composition of neuronal types and set of neuronal connections, which among other factors, determine their neuronal dynamics. Most works characterize the neuronal dynamics usi...
The dorsal (DRN) and median (MRN) raphe are the main serotonergic nuclei, being implicated in sleep and mood regulation. The DRN is mainly serotonergic, where neurons have regular spiking activity, slow firing rate (FR), and long action potential duration (APD). The MRN is divided in a median serotonergic region and a paramedian region, containing...
The melanin-concentrating hormone (MCH) is a neuromodulatory peptide present in neurons located in the postero-lateral hypothalamus and incerto-hypothalamic area. These neurons project widely throughout the central nervous system, including the serotonergic dorsal raphe nucleus (DR), a waking-promoting and REM sleep permissive region. Although it i...
Serotonergic neurons of the median raphe nucleus (MnR) and hypothalamic melanin-concentrating hormone (MCH)-containing neurons, have been involved in the control of REM sleep and mood.
In the present study, we examined in rats and cats the anatomical relationship between MCH-containing fibers and MnR neurons, as well as the presence of MCHergic rec...
Hypothalamic neurons that utilize melanin-concentrating hormone (MCH) as a neuromodulator are localized in the postero-lateral hypothalamus and incerto-hypothalamic area. These neurons send dense projections to the dorsal raphe nucleus (DRN). Serotonergic neurons of the DRN are involved in the control of sleep and play a critical role in major depr...
Introducción: la depresión mayor (DM) es una enfermedad psiquiátrica frecuente, con importante morbilidad y una relación estrecha con el suicidio.
Objetivo: hacer una puesta a punto de los avances en el estudio de la neurobiología de la DM, enfocándonos en el posible rol de la hormona concentradora de melanina (MCH) en esta patología.
Metodología...
