
Andre ShomoronyNew York Presbyterian Hospital | NYP · Department of Ear, Nose, and Throat (Otorhinolaryngology)
Andre Shomorony
Doctor of Medicine
About
21
Publications
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Publications
Publications (21)
Objective
To understand post‐pandemic interest in plastic surgery procedures via Joinpoint analysis of Google Trends search data.
Methods
Google Trends was used to quantify search volumes from January 2019–December 2022 for select cosmetic face and body procedures in the United States. A keyword analytic tool (Keywords Everywhere) extracted absolu...
Importance
Facial trauma makes up a significant number of emergency room visits, with morbidity costs in excess of 1 billion dollars each year. Few studies have evaluated the economic outcomes of management and inpatient burden of facial trauma, most focusing solely on the mandible and isolated midface fractures.
Objective
The authors aim to evalu...
Objective
To discuss patient demographics and management and better understand the economic impact associated with the treatment of facial fractures at a major metropolitan level 1 trauma center.
Study Design
Retrospective chart review.
Methods
We identified 5088 facial fractures in 2479 patients who presented from 2008 to 2022. Patient demograph...
Background: Few studies have critically evaluated the quality of data obtained during telemedical evaluations of patients with nasal complaints. Objective: To compare the quality of data provided by remote endoscopic and external nasal examination with those by in-person evaluations for rhinoplasty and functional nasal surgery, measured by detectab...
Purpose
To identify areas of critical otolaryngology contributions to inpatient care resistant to disruption by the COVID-19 pandemic.
Methods
Medical records of 614 otolaryngology consults seen between January and June of 2019 and 602 seen between January and June of 2020 were reviewed. Extracted data included patient demographics, SARS-CoV-2 sta...
Rhinoplasty is one of the most common facial plastic surgical procedures, performed for cosmesis or to improve breathing, while rhinologic surgery typically refers to endoscopic sinus surgery, performed to alleviate symptoms of chronic rhinosinusitis. Commonly coupled with these procedures is the straightening of a deviated septum, termed septoplas...
Purpose
Telemedicine use in otolaryngology waxed and waned during the COVID-19 pandemic outbreak in the U.S. Assessing the patterns of telemedicine use and its perceived limitations during the COVID-19 outbreak in 2020 allows identification and correction of impediments to consistent telemedicine use by otolaryngologists.
Materials and methods
Ful...
Background
High-risk human papilloma virus (HPV) is a driver of the development of oropharyngeal squamous cell carcinomas (SCC), while its role in other head and neck subsites, including the oral cavity, is debated. HPV detection in tissue is assayed directly and indirectly using various methods, including p16 surrogate immunohistochemistry (IHC),...
There is clinical and scientific interest in developing local anesthetics with prolonged durations of effect from single injections. The need for such is highlighted by the current opioid epidemic. Site 1 sodium channel blockers such as tetrodotoxin (TTX) are extremely potent, and can provide very long nerve blocks but the duration is limited by th...
Background:
Capsaicin, the active component of chili peppers, can produce sensory-selective peripheral nerve blockade. Coadministration of capsaicin and tetrodotoxin, a site-1 sodium channel blocker, can achieve a synergistic effect on duration of nerve blocks. However, capsaicin can be neurotoxic, and tetrodotoxin can cause systemic toxicity. We...
Cytokines play an important role in dysregulated immune responses to infection, pancreatitis, ischemia/reperfusion injury, burns, hemorrhage, cardiopulmonary bypass, trauma, and many other diseases. Moreover, the imbalance between inflammatory and antiinflammatory cytokines can have deleterious effects. Here, we demonstrated highly selective blood-...
The efficacy of tetrodotoxin (TTX), a very potent local anesthetic, is limited by its poor penetration through barriers to axonal surfaces. To address this issue, we encapsulated TTX in hollow silica nanoparticles (TTX-HSN) and injected them at the sciatic nerve in rats. TTX-HSN achieved an increased frequency of successful blocks, prolonged the du...
The complete stack of block face images from β cell #1 analysed in Table 1, together with the surface rendering of the cell's plasma membrane.
div class="title">Architecture of Pancreatic Islets Imaged by Serial Block Face SEM
- Volume 21 Issue S3 - R.D. Leapman, M.A. Aronova, A. Shomorony, C.R. Pfeifer, J.D. Hoyne, G.N. Calco, B.C. Kuo, G. Zhang, H. Xu, C. Tao, A.L. Notkins
A combination of two-dimensional (2D) and three-dimensional (3D) analyses of tissue volume ultrastructure acquired by serial block face scanning electron microscopy can greatly shorten the time required to obtain quantitative information from big data sets that contain many billions of voxels. Thus, to analyse the number of organelles of a specific...
Serial block-face scanning electron microscopy (SBF-SEM) provides three-dimensional ultrastructure of biological tissues at the nanometer scale (Denk and Horstmann, 2004). Previous studies have applied this technique to visualize the architecture of pancreatic islets of Langerhans in wild-type mice. Initial results indicate that an average beta cel...
We have applied serial block-face scanning electron microscopy (SBF-SEM) to measure parameters that describe the architecture of pancreatic islets of Langerhans, microscopic endocrine organs that secrete insulin and glucagon for control of blood glucose. By analyzing entire mouse islets, we show that it is possible to determine (1) the distribution...
Serial block-face scanning electron microscopy (SBF-SEM) can be used to image large (100-micrometer size) volumes of biological tissue, and thus complements standard transmission electron tomography, as well as scanning transmission electron tomography. SBF-SEM is attractive not only for its ability to generate high-resolution three-dimensional ult...
An immuno-DNA-directed assembly technique based on bifunctional conjugates of uniquely designed-ssDNA codes and antibodies specific to cell surface receptors enables rapid assembly of heterotypic cells into multicellular systems. It is a versatile and modular approach, and upon further development may find applications in microtissue engineering.