Andre Mueller

Andre Mueller
Cosateq GmbH & Co.KG · Research & Development

Dr.

About

12
Publications
1,497
Reads
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348
Citations
Education
July 2006 - November 2017
Ulm University
Field of study
  • Visualization in Functional Genomics
September 1993 - December 2000
Ulm University
Field of study
  • Computer Science

Publications

Publications (12)
Article
Full-text available
Visualising data as diagrams using visual attributes such as colour, shape, size, and orientation is challenging. In particular, large data sets demand graphical display as an essential step in the analysis. In order to achieve comprehension often different attributes need to be displayed simultaneously. In this work a comprehensible bivariate, per...
Article
Full-text available
Microarray experiments generate vast amounts of data. The functional context of differentially expressed genes can be assessed by querying the Gene Ontology (GO) database via GoMiner. Directed acyclic graph representations, which are used to depict GO categories enriched with differentially expressed genes, are difficult to interpret and, depending...
Data
Full-text available
Implementation details. Details on the software implementation.
Article
Full-text available
Primary mediastinal B-cell lymphoma (PMBL) is an aggressive extranodal B-cell non-Hodgkin's lymphoma with specific clinical, histopathological and genomic features. To characterize further the genotype of PMBL, we analyzed 37 tumor samples and PMBL cell lines Med-B1 and Karpas1106P using array-based comparative genomic hybridization (matrix- or arr...
Article
Motivation: DNA copy number aberrations are frequently found in different types of cancer. Recent developments of microarray-based approaches have broadened the knowledge on number and structure of such aberrations. High-density single nucleotide polymorphism (SNP) microarrays provide an extremely high resolution with up to 500,000 SNPs per genome...
Conference Paper
Microarray technologies are increasingly being used in biological and medical sciences for high throughput analyses of genetic information on the genome, transcriptome and proteome levels. The differentiation between cancerous and benign processes in the body often poses a difficult diagnostic problem in the clinical setting while being of major im...
Conference Paper
Gene expression data studies are often concerned with comparing experimental versus control conditions. Ratios of gene expression values, fold changes, are therefore commonly used as biologically meaningful markers. Visual representations are inevitable for the explorative analysis of data. Fold changes alone are no reliable markers, since low sign...
Article
Full-text available
Microarray experiments generate vast amounts of data. The unknown or only partially known functional context of differentially expressed genes may be assessed by querying the Gene Ontology database via GOMiner. Resulting tree representations are difficult to interpret and are not suited for visualization of this type of data. Methods are needed to...
Conference Paper
Full-text available
Aim of this study was to extract robust features from cine magnetic resonance images (MRI) for phase estimation in dilated cardiomyopathy (DCM) patients. The found features may serve as additional diagnostic parameters. Previously found markers could be improved and were applied to an enlarged subject group. Four quantitative features based on the...
Conference Paper
Full-text available
Aim of this study was to evaluate quantitative parameters for inter- and intra-ventricular dyssynchronicity measurement. 10 patients with severely reduced left ventricular function (LVF) and variable QRS duration (70% had left bundle branch blockation; LBBB) and six healthy subjects (control) were examined with cine magnetic resonance imaging. The...
Article
Many experiments in the biomedical field generate vast amounts of data. This is especially true for microarray experiments which measure the expression levels of thousands of genes simultaneously. In this context the display of functional information attributed to the individual gene is important to obtain an overview of the major processes involve...

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Projects (2)