
Anca Daniela BrăilaUniversity of Maine at Farmington | UMF · Moase
Anca Daniela Brăila
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36
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Publications (36)
Cervical intraepithelial neoplasia (CIN) is a premalignant cervical condition closely linked to persistent high-risk HPV infection, a major risk factor for cervical cancer. This study aims to investigate the relationship between cervicovaginal infections, HPV infection, and CIN development in 94 Romanian women with cervical lesions. Comprehensive a...
The oral mycobiome plays a critical role in maintaining oral and systemic health, with its composition and function influenced by various physiological and environmental factors. This descriptive review explores the changes in the oral mycobiome among postmenopausal women, examining how aging and associated inflammatory processes contribute to thes...
Background: Oral wound healing in the aging population is a multifaceted issue requiring a comprehensive approach, considering the physiological changes that come with aging and the frequent presence of comorbidities. Methods: This descriptive review summarizes the factors influencing oral wound healing in aging patients, including age-related phys...
The aim of the study is to evaluate a group of women diagnosed with polycystic ovary syndrome (PCOS), compared to a control group consisting of healthy women, in order to reveal the hormonal and metabolic changes characteristic of PCOS. The study was conducted over a period of two years, in the Gynecology Clinics, of the University of Medicine and...
Cleft lip and/or palate are prevalent congenital anomalies. Early and accurate diagnosis allows proper case management. The Objective: This retrospective cohort study aimed to investigate the association between cleft lip and palate and other congenital anomalies. Methods: This study analyzed 17 pregnancies prenatally diagnosed with cleft lip and p...
Pregnancy-induced hypertension is diagnosed by an increase in systolic blood pressure above 140 mmHg and diastolic blood pressure above 90 mmHg, after 20 weeks of gestational age, in a normotensive pregnant woman before pregnancy. The preeclamptic syndrome is specific to gestation, can affect all organs, and is characterized by the associa...
The management of pregnancy associated with gestational hypertension is performed depending on the severity of the hypertension, according to gestational age and the presence or absence of complications. The early identification of worsening preeclampsia involves the prevention of maternal complications (eclampsia, HELLP syndrome, uteroplac...
Despite advances in fetal monitoring during labor, one of the most critical causes of neonatal death and neurologic injuries remains intrapartum asphyxia. Umbilical cord gases can be used to detect acidosis and fetal distress. We conducted a retrospective, multicenter study to evaluate umbilical cord blood pH and lactate as a mean of evaluating the...
The treatment of cervical intraepithelial neoplasia aims at removing the squamocolumnar junction area, including abnormal tissues, up to the healthy tissue. Old postpartum perineal tears associated with cystorectocele, hypertrophic cervical elongation, and first and second degree uterine prolapse are pelvic static disorders. Particular aspects of p...
The treatment of cervical intraepithelial neoplasia aims at removing the junction area, including abnormal tissues. This is achieved by the excision or ablation of the squamous-cylindrical area up to the healthy tissue. In the case of persistence of high-grade lesions after repeated excision and if the patient does not want to preserve fertility, h...
Sjögren's syndrome (SS) is a multisystemic disease mainly characterized by the hypofunction of the lachrymal and salivary glands and can be either primary or secondary, when related to other autoimmune pathologies. We present the case of a 35-year-old female admitted in the Department of Obstetrics and Gynecology for pregnancy monitoring. The patie...
The notion of cervical intraepithelial neoplasia (CIN) is the lesion of the cervix squamous epithelium, the precursor lesion of invasive cancer, diagnosed by biopsy and histopathological examination. The objective of the study is to evaluate the conization as a biopsy and treatment method, with the entire excision of the lesion together with a safe...
There has been a rise in the number of frozen embryo transfers (FET), ever since clinicians started adopting the "freeze-all" policy as a method of prevention for the hyperstimulation syndrome. Even though people have made great advances in this area, the pregnancy rates haven't changed much, so we constantly need to find new ways to improve in vit...
Premature birth is considered to be the consequence of independent alterations in the cervix and in the uterus. During labor, for full-Term birth, as well as for premature birth, the cervix changes, from firm, long and closed, to soft and pliable, through a biochemical process characterized by the reshaping of the extracellular matrix and a growth...
Ectopic pregnancy is a polymorphic disorder, with difficult early diagnosis, and in late stages it determines serious complications, targeting obstetrical and vital prognosis of the patient. A precise and early diagnosis is supported on ultrasound and dosage of the β-hCG dynamics. The presence of β-hCG, the empty uterine cavity on ultrasound tests,...
The idiopathic inflammatory myopathies (IIM) are a group of autoimmune disorders characterized by chronic muscle weakness and the presence of inflammatory cell infiltrates in skeletal muscles. The current report presents a rare case of bone infarction in a patient with polymyositis, possibly related to the corticosteroid treatment, metabolic profil...
The cervical cancer prevention involves the identification and the eradication of the precursor and invasive lesions, early, through cytological screening. The lack of screening determines an important increase of the cervical cancer rates in socially disadvantaged women. The cytological screening detects most of the cervical neoplasia in premalign...
Much attention is being directed nowadays toward individualized medicine. Worldwide clinicians use different types of protocols for ovarian stimulation during human assisted reproduction techniques. In the last few years, researchers have tried to find the most appropriate stimulation protocol taking into consideration the ovarian response, clinica...
Introduction:
Gait evaluation and assessment of motor performance are of utmost importance in the clinical management of multiple sclerosis (MS). A new approach to the analysis of static and dynamic balance of MS patients is the use of complex biomechanical analysis that includes an analysis of the distribution of the center of pressure (DCP) and...
The severe form of retroplacental hematoma is a serious accident in the second stage of pregnancy and at birth with frightening for the mother and fetus that often lead to death. The pathological mechanism presumes conditions for a "special ground" capital for the "efficiency" of the acute intradecidual vascular accident with the rupture of the ute...
The prevalence of endometrial cancer among asymptomatic women is rather reduced also due to the absence of a cost-efficient test, as there are no ideal screening examinations for endometrial cancer. Several methods were proposed in medical practice to discover endometrial neoplasia at an early stage, among which: endometrial biopsy, endovaginal ult...
Introduction: Periapical granuloma is one of the most frequent periodontal pathology and belongs to the group named as apical periodontitis. Materials and Methods: Out of 78 of diagnosed granulomas, we selected samples that we analyzed histologically and immunohistochemically. Results: The histopathological aspect has been dominated by the presence...
Clear cell carcinoma (CCC) of the female genital tract usually arises in the ovary, endometrium, cervix and vagina. A rare site for CCC is the vulva, and moreover even rarer are the cases involving the Bartholin gland. A 54-year-old female was admitted for a 1.5×2 cm tumor at the level of the right Bartholin gland. The magnetic resonance imaging (M...
While eclampsia is a serious complication of the preeclampsia specific for the gestational period-the epilepsy is a pre-existing pathology of pregnancy. Both syndromes are characterized by neuroconvulsive syndrome. On the other hand, epilepsy can be aggravated by the association of preeclampsia and eclampsia during the pregnancy, both by increasing...
The cervical cancer is the worldwide second neoplasia in women, after the breast cancer. The incidence of invasive carcinoma in pregnancy is 1÷2000 to 1÷10 000 pregnancies. In most of the studies, almost all the patients had microinvasive carcinoma or limited cervical carcinoma at the cervix level. In the uteroplacental apoplexy, pathologically, re...
Hysteroscopy and uterine curettage are required in cases of atypical hyperplasia in premenopause and in all cases of hyperplasia with/without atypia in postmenopausal women. Biopsic curettage is the method of choice in the diagnosis of endometrial pathology. Transvaginal ultrasound and Doppler examination are useful in assessing the risk of endomet...
The research focused on a systematic review of 959 cases operated for uterine fibromyoma (24.8%) from 3859 gynecological surgeries performed over a period of 10 years (2000-2010).
The important parameters were those related to the general clinical and laboratory data, and especially those focused on the macro- and microscopic histopathological diag...
Objective: The role of inositol 1,4,5 triphosphate (IP3)-sensitive calcium stores on angiotensin II (AG II)-induced uterine contraction was studied by blocking IP3 receptors with xestospongin C (Xe C). This is for the first time when Xe C is used to evaluate the implication of IP3-sensible intracellular calcium stores, during AG II-induced uterine...
Objective: The role of inositol 1,4,5 triphosphate (IP3)-sensitive calcium stores on angiotensin II (AG II)-induced uterine contraction was studied by blocking IP3 receptors with xestospongin C (Xe C). This is for the first time when Xe C is used to evaluate the implication of IP3-sensible intracellular calcium stores, during AG II-induced uterine...
The benign tumors and ovarian dystrophical lesions (pseudo-tumors) have an important place in gynecological pathology as follows: high incidence regardless of the age; the lack of clinical findings in early stages, and in the same time, the difficulties of early diagnosis; the multitude of anatomo-clinical and microscopical varieties; the possibili...