
Anas Siraj DabloolUmm al-Qura University · Department of Public Health- Health Sciences College at Al.leith
Anas Siraj Dablool
Associate Professor
Looking for collaborators and new position and a scientific friendship
About
68
Publications
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Introduction
Anas Dablool currently works as Associate Professor at the Department of Public Health- Health Sciences College at Al.leith, Umm Al-Qura University and medical Microbiology Consultant. Anas research interest encomapsees Medical Microbiology, Food & water Microbiology, Environmental Sciences and Ecology.
Additional affiliations
January 2013 - November 2016
January 2013 - present
Education
January 2006 - January 2009
January 1999 - January 2002
January 1991 - January 1994
Publications
Publications (68)
Revolutionizing and identifying novel drug targets in Citrobacter koseri via subtractive proteomics and development of a multi-epitope vaccine using reverse vaccinology and immuno-informatics, Journal of Biomolecular Structure and Dynamics, ABSTRACT Citrobacter koseri is a gram-negative rod that has been linked to infections in people with signific...
Revolutionizing and identifying novel drug targets in Citrobacter koseri via subtractive proteomics and development of a multi-epitope vaccine using reverse vaccinology and immuno-informatics, Journal of Biomolecular Structure and Dynamics, ABSTRACT Citrobacter koseri is a gram-negative rod that has been linked to infections in people with signific...
Background: The spread of antibiotic-resistance genes in ecosystems has led to the emergence of antibiotic-resistant bacteria, leading to various antibiotic-resistant diseases worldwide. Materials and methods: This study aimed to characterize mute-drug resistant Staphylococci isolates from urine and wounds. We obtained 400 bacterial isolates that w...
Original Research Article Background: The spread of antibiotic-resistance genes in ecosystems has led to the emergence of antibiotic-resistant bacteria, leading to various antibiotic-resistant diseases worldwide. Materials and methods: This study aimed to characterize mute-drug resistant Staphylococci isolates from urine and wounds. We obtained 400...
The study was aimed to characterize the antioxidant and anti-microbial activities of Cynodon dactylon with special reference on its precise biochemical analysis. Physiological analysis that total carotenoids content (0.3884 ± 0.0172 mg/g), total chlorophyll content (6.1460 ± 0.2915 mg/g), total phenolic contents (13.4703 ± 0.1494 mg/g), chlorophyll...
Objective:
The aim of the present study is to determine the in vivo and in silico anti-inflammatory effect of Azadirachta indica (A. indica) in carrageenan-induced rats and its blood biomarkers. A. indica (Neem) is a widely used medicinal plant across the world, especially in Pakistan. Neem leaves have been traditionally used for the synthesis of...
OBJECTIVE: The aim of the present study is to determine the in vivo and in silico anti-inflammatory effect of Azadirachta in-dica (A. indica) in carrageenan-induced rats and its blood biomarkers. A. indica (Neem) is a widely used medicinal plant across the world, especially in Pakistan. Neem leaves have been traditionally used for the synthesis of...
Extensive pesticides (herbicides) use is negatively disturbing the environment and humans. Pesticide bioremediation with eco-friendly techniques bears prime importance. This study aimed to isolate and characterize three different herbicides (metribuzin, clodinafop- propargyl, MCPA (2-methyl, 4 chlorophenoxyacetic acids) and Bromoxynil) degrading ba...
Background:
The antibiogram profile could be helpful in the selection of the most appropriate antimicrobial treatment for microbial infection and even useful to monitor antibiotic resistance.
Objective:
This study aims to identify the bacteria in the urine through urine culture and perform their antibiogram to determine the resistance profile be...
Background:
Eating disorders (EDs) are characterised by an abnormal attitude towards food that causes someone to change their eating habits and behaviour. This study aimed to investigate the prevalence of EDs and their associated factors among female going-school adolescents in Jeddah, Saudi Arabia.
Methods:
A cross-sectional study was conducted...
Background: Infection with the hepatitis B virus is a major global health concern. In Peshawar, HBV infection is widespread and affects all demographics, especially pregnant women. Objective: The purpose of this research is to determine how common HBV is, as well as the risks and complications associated with various clinical parameters and patient...
The widespread and indiscriminate use of broad-spectrum antibiotics leads to microbial resistance, which causes major problems in the treatment of infectious diseases. However, advances in nanotechnology have opened up new domains for the synthesis and use of nanoparticles against multidrug-resistant pathogens. The traditional approaches for nanopa...
Citation: Aziz, T.; Naveed, M.; Makhdoom, S.I.; Ali, U.; Mughal, M.S.; Sarwar, A.; Khan, A.A.; Zhennai, Y.; Sameeh, M.Y.; Dablool, A.S.; et al. Genome Investigation and Functional Annotation of Lactiplantibacillus plantarum YW11 Revealing Streptin and Ruminococcin-A as Potent Nutritive Bacteriocins against Gut Symbiotic Pathogens. Molecules 2023, 2...
Chinese fermented sausage is a famous fermented meat product with a complex microbiota that has a potential impact on flavor and quality. In this study, Lactobacillus plantarum MSZ2 and Staphylococcus xylosus YCC3 were used as starter cultures to investigate the change in bacterial diversity, metabolic pathways, and flavor compounds during the ripe...
In the current decade, nanoparticles are synthesized using solvents that are environmentally friendly. A number of nanoparticles have been synthesized at room temperature using water as a solvent, such as gold (Au) and silver (Ag) nanoparticles. As part of nanotechnology, nanoparticles are synthesized through biological processes. Biological method...
Nanotechnology has emerged as a new tool to combat phytopathogens in agricultural crops. Cucurbit chlorotic yellows virus (CCYV) mainly infects Solanaceae crops and causes significant crop losses. Nanomaterials (NMs) may have efficacy against plant viruses, but the mechanisms underlying complex nanomaterials-plant-virus interactions remain elusive....
Pseudomonas aeruginosa spp are the most prevalent bacteria that cause nosocomial
infections in hospitals. Most antibiotics, including novel new β-lactams, are already resistant
to them, and they can become resistant during treatment, which can make the treatment fail.
P. aeruginosa isolates from ICU patients who had Per-1 and VEB-1 were the main fo...
For the treatment of various infections, a variety of antimicrobial drugs are formulated. Nevertheless, many bacterial infections now exhibit antibiotic resistance due to the widespread utilization antibiotics. Methicillin-resistant among the most dangerous multidrug-resistant bacteria is Staphylococcus aureus (MRSA). Vancomycin became a viable the...
sa (A.A.A.); a.alamri@tu.edu.sa (A.S.A.); m.alhomrani@tu.edu.sa (M.A.) Abstract: Providencia heimbachae, a Gram-ve, rod-shaped, and opportunistic bacteria isolated from the urine, feces, and skin of humans engage in a wide range of infectious diseases such as urinary tract infection (UTI), gastroenteritis, and bacteremia. This bacterium belongs to...
Abstract: Bionanotechnology is the combination of biotechnology and nanotechnology for the development
of biosynthetic and environmentally friendly nanomaterial synthesis technology. The
presented research work adopted a reliable and environmentally sustainable approach to manufacturing
silver nanoparticles from Brachychiton populneus (BP-AgNPs) le...
The current study was devised to develop alternative, nonantibiotic, and economically viable treatments for bovine mastitis. The concentration of 6.25 μg/mL (25 nm) CuNPs was selected as intramammary (IM) treatment in S. aureus-induced mastitis in rats as this concentration showed a significant zone of inhibition through the in vitro sensitivity te...
Bionanotechnology is the combination of biotechnology and nanotechnology for the development of biosynthetic and environmentally friendly nanomaterial synthesis technology. The presented research work adopted a reliable and environmentally sustainable approach to manufacturing silver nanoparticles from Brachychiton populneus (BP-AgNPs) leaf extract...
Fermentation of available sugars in milk by yogurt starter culture initially and later by Saccharomyces boulardii (Probiotic yeast) improves the bioavailability of nutrients and produces bioactive substances and volatile compounds that enhance consumer acceptability. The combination of S. boulardii, a unique species of probiotic yeast, and inulin,...
Parthenium hysterophorus L. is a poisonous Asteraceae weed. The phytochemical profile, antioxidant activity, total phenolic contents (TPC), total flavonoid contents (TFC), and cytotoxicity of Parthenium hysterophorus L. flower extract were evaluated in this study, and the toxic effects were assessed in rabbits. The HPLC-DAD system was used for phyt...
Pseudomonas aeruginosa spp are the most prevalent bacteria that cause nosocomial infections in hospitals. Most antibiotics, including novel new β-lactams, are already resistant to them, and they can become resistant during treatment, which can make the treatment fail. P. aeruginosa isolates from ICU patients who had Per-1 and VEB-1 were the main fo...
Pesticides are a class of xenobiotic compounds that are recalcitrant and show persistence in the environment for a longer period of time. Research studies have linked their potential for mutagenicity, teratogenicity, and carcinogenicity. The accumulation of pesticides in water sources due to runoff from agricultural lands has posed a serious threat...
Lactobacillus (LAB) genera are considered important functional food but are found to have a short shelf life. In this study, two LAB, Lactobacillus plantarum (Lp) and Lactobacillus rhamnosus (Lr), were isolated from sheep's milk, and whole-genome sequencing was carried out by using 16s rRNA Illumina Nextseq, the Netherlands. e LAB were encapsulated...
Multi drug resistance is increasing day by day due to misuse of antibiotics. Several potent metabolites are produced by fungi. Synthesis of silver nanoparticle (AgNPs) Due to its simple, harmless, time-saving, and cost-effective characteristics, it has acquired great popularity in recent years. A variety of analytical techniques were used to synthe...
Biosynthesis, optimization, physicochemical properties and nanomedicinal applications of the Ephedra intermedia Schrenk & C.A.Mey mediated silver nanoparticles (Et-AgNPs) has been established. The effect of different parameters like precursor concentration, extract to precursor ratio pH and temperature were assessed on the synthesis and properties...
Lactiplantibacillus is among the most extensively studied bacterial specie belonging to the genus Lactobacillus with proven probiotic and health promoting effects. These beneficial effects are generally strains specific but the underlying molecular mechanisms are still not fully understood. Dissecting the determinants behind probiotic topographies...
The risk of acquisition of malaria in Saudi Arabia is limited to the Southwestern part of the country, with the highest number of cases reported from Gizan and Aseer regions. The Eastern Province of Saudi Arabia is free of local transmission of malaria since 1978. The lack of transmission of malaria in this province is related to the malaria contro...
Premarital screenings are such an important public health measure for couples planning to get married, which helps them lead healthy lives and give birth to healthy children. During this process couples are medically tested before their wedding to check out their health condition. If one of the spouses is infected or carries a disease, it can be tr...
In the current investigation, silver/gold nanoparticles (NPs) were synthesized using two methods: chemical and biological, and then characterized colloidal solutions of both NPs using UV-Vis, transmission electron microscopy (TEM) and zeta potential analyzers, X-ray powder diffraction (XRD), and energy dispersive X-ray (EDX) as well as the ToxTrak...
Brain disorders such as Alzheimer’s and Parkinson’s disease (PD) are irreversible conditions with several cognitive problems, including learning disabilities, memory loss, movement abnormalities, and speech problems. These disorders are caused by a variety of factors, mainly due to the toxic pollutants-induced biochemical changes in protein product...
Virulence Characteristics of Biofilm-Forming Acinetobacter baumannii in Clinical Isolates Using a Galleria mellonella Model. Microorganisms 2021, 9, 2365. Abstract: Acinetobacter baumannii is a Gram-negative coccobacillus responsible for severe hospital-acquired infections, particularly in intensive care units (ICUs). The current study was designed...
Background and aim:
The poultry meat and its products are considered ideal media for bacterial growth and spoilage, as they are highly nutritive with a favorable pH. The food industry has focused its attention on a great diversity of plant species as food preservatives. The aim of this study was to investigate the presence of Staphylococcus aureus...
Soil salinity stress has become a serious roadblock for food production worldwide since it is one of the key factors affecting agricultural productivity. Salinity and drought are predicted to cause considerable loss of crops. To deal with this difficult situation, a variety of strategies have been developed, including plant breeding, plant genetic...
The risk of acquisition of malaria in Saudi Arabia is limited to the Southwestern part of the country, with the highest number of cases reported from Gizan and Aseer regions. The Eastern Province of Saudi Arabia is free of local transmission of malaria since 1978. The lack of transmission of malaria in this province is related to the malaria contro...
The study was aimed to screen the presence of phytoconstituents and determine distinct in vitro medicinal traits of aqueous and ethanolic extracts of Solanum virginianum dried fruits. Aqueous and ethanolic extract showed total phenolic content of 207.5±0.16 and 268.4±0.42 GAE/mg, respectively. Likewise, total flavonoid content of 50.12±0.39 and 192...
Treatment of microbial infections and inflammatory conditions have many challenges in terms of efficacy and safety issues. Novel approaches such as nanoparticles based drug delivery system have shown promising results to solve some of these problems. The aim of this study was to exploit the efficacy of the synthesized silver nanoparticles. In this...
For consumers, the water composition is indicated on a label attached to the water bottle. Reports
about wrong label information were the motivation for this comparative study of the real content of 20
different bottled water brands from Saudi Arabia and 19 other brands from different countries in Asia,
Oceania, Africa, and Europe. The pH, total...
In the Kingdom of Saudi Arabia (KSA), there are two types of drinking water, tap water, and bottled water. In order to find which water is good for human health, a comparison study performed between tap water and bottled water in the KSA. The data of tap water obtained from the previously published papers for three different regions, Central Region...
Food borne diseases (FBDs) can occur due to the health status of the food handlers. The present study aimed to assess food hygiene knowledge, attitude and practices among hospital food handlers of ElManagil City, Sudan. A cross-sectional study was administered to evaluate knowledge, attitudes, and practices, in food hygiene among hospital food hand...
A longitudinal descriptive study was performed for the surveillance of pulmonary tuberculosis (TB) cases registered daily within one year at health centers of Al Taif province, Saudi Arabia, using different diagnostic tools. To determine the epidemiology of TB and the performance of diagnostic methods used to confirm cases among outpatient admissio...
Chronic conditions are thought to affect ahigh number of the general population of pilgrims and Umrah visitors. With a little planning and preparation, people with chronic illnesses should have safe and enjoyable Umrah rituals. The study aimed to characterize the association between chronic diseases and dietary regimens among Umrah visitors. Data c...
A study on microbial, physical and chemical analysis of bottled water sold in Makkah, Saudi Arabia was carried out. Twenty brands of bottled waters consisting of both purified and ground water spring types collected randomly from various retail outlets in Makkah and Holy places, KSA during the Hajj, were assessed for their suitability for drinking...
Although bottled water meets quality standards, a variety of bacteria can be detected in most commercially bottled water. The present study was carried out to evaluate the bacteriological quality of bottled Drinking water in Alaith city, Makkah province, KSA.
Forty five bottles of different 9 brands of bottled water were randomly selected from diff...
Background: Cancer caused over 8 million deaths worldwide in 2013 and has moved from the third leading cause of death in 1990 to the second leading cause behind cardiovascular disease in 2013. Cancer can be reduced and controlled by implementing evidence-based strategies for cancer prevention, early detection of cancer and management of patients wi...
Introduction: People rely on the quality of the bottled drinking water, expecting it to be free of microbial contamination and health hazards. Objectives of a comparative study of microbiology, chemistry, and physics on the quality of bottled water samples from different countries. Methods: All bottled water samples sold and collected. Electrical c...
year by 2030. This represents an increase of 68% compared with 2012 (66% in low and medium HDI countries and 56% in high and very high HDI countries). [4,5] The most commonly diagnosed cancers in high HDI countries (according to the WHO classification, Kingdom of Saudi Arabia (KSA) belong to this group of countries) are breast, lung, prostate, bowe...
Several methods of Deoxyribonucleic acid (DNA) extraction have been applied to extract bacterial DNA. The amount and the quality of the DNA obtained for each one of those methods are variable. The study aimed to evaluate bacterial DNA extraction using conventional boiling method followed by alcohol precipitation. DNA extraction from Gram negative b...
Abstract: Several methods of Deoxyribonucleic acid (DNA) extraction have been applied to extract bacterial DNA. The amount and the quality of the DNA obtained for each one of those methods are variable. The study aimed to evaluate bacterial DNA extraction using conventional boiling method followed by alcohol precipitation. DNA extraction from Gram...
During Hajj, millions of Muslim pilgrims gather in the holy sites (Arafat, Muzdalifah and
Mina) in Holy Makkah. The management of these gatherings and crowds requires a
tremendous effort and great potential by the concerned Saudi authorities, as Saudi
Arabia is one of the most prominent countries that manage human crowds and mass
gatherings worldwi...
This study was carried out to assess quality of water used in Dental Chair Units (DCUs) in Makkah Primary health care center (PHCC), Saudi Arabia. Out of thirty Primary health care center located inside Makkah city, and used Desalinated sea water. The findings of this study revealed that maximum concentration of Potassium (K) was 2.6 mg in sample f...
Saudi Arabia is leading country for managements of human crowds and gatherings, where various services regarding basic life requirements and sanitation (toilets, bathrooms, Ablution sinks) are provided around the Holy mosque in Makkah. Too much toilets are available, distributed around different areas of the Holy mosque (Haram). The present study a...
Enterotoxin production by Staphylococcus aureus has been recognized as a major health problem. Staphylococcus enterotoxins have been isolated in the community and hospitals environments. The present study detected the prevalence of S. aureus and SEs in food handlers of community- and hospital-located kitchens. About 400 adult food handlers, who wor...
A study was conducted to investigate the quality of water that used in food premises in Makkah, Saudi Arabia. A total of 288 water samples were collected from different food establishments. The collected samples were taken from underground tanks (6 samples), roof tanks (13 samples), taps (264 samples) and desalination stations (5). Laboratory analy...
A study on enterotoxin-producing Staphylococcus areus was carried out among food handlers in hospital-located kitchens in Makkah, Saudi Arabia to detect the enterotoxigenic S. areus in specimens taken from noses, fingernails, throats and stool of food handlers and to identify susceptibility of S. areus to certain antibiotics. The study group includ...
Groundwater is a very important resource, particularly in arid regions. In Makkah, which is the religious capital of the kingdom, water supply is provided from the aquifers of many valleys inside and around it, including Al Hussineh and WadiNaman valley that considered tobe important groundwater sources . In this study, the chemical and physicalpar...
The overuse of clinical laboratory services has been documented for many years. This overuse use does not contribute to the quality of medical care, does not shorten hospital stay, nor reduce mortality. The utilization of diagnostic labora-tories has increased over the last decade around the world. This increased laboratory use is appropriate if it...
Physicians are critical, vital and essential among human resources and play an important role in success of information technology adoption in medical practices. The aim of the present study was to assess physicians' use of, knowledge about and attitudes toward computer applications in public and private hospitals. The study was conducted at 45 hos...
Food poisoning during Hajj season is one of the main hazardous issues where most of the health services in Saudi Arabia are targeting to minimize every year during Hajj seasons. Ordinarily, food handlers are sub-jected to medical examination before assignment to work. However, they are mostly lacking proper training in food handling operations, mas...
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