Ana Hilda Márquez

Universidad Metropolitana | UMET · Facultad de Salud y Cultura Física (FSCF)

We present a phase shifting interferometry system for the study of the early adhesion process for osteoblast-like cells, through an interference microscope. Optical phase maps from the cells are obtained experimentally as a function of cell adhesion time. The process is carried out on surfaces of metallic materials relevant to the development of bo...

The article presents the use of an interference microscope, using a Mirau objective for the study of the early adhesion process of osteoblast-like bone cells, using the phase shifting technique. The process is carried out on surgical stainless steel surfaces of interest for the development of bone implants. Experimental phase maps are directly rela...

El grado de glicosilación del colágeno óseo regula la adhesión y la capacidad de biomineralizar de las células óseas Abstract— In the bone tissue, collagen is the most abundant protein, conforming 90% of the organic matrix of this mineral-ized structure. Different works indicate that in postmeno-pausal osteoporosis, the early degradation of the bon...

RESUMEN Estudios epidemiológicos demuestran que dietas ricas en flavonoides previenen afecciones relacionadas con la menopausia tales como la osteoporosis, debido a que poseen una estructura similar al 17β-estradiol. Por ello pueden ser empleados como sustitutos terapéuticos y de allí su nombre más conocido: fitoestrógenos. En Venezuela, se ha repo...

El brote de enfermedad COVID-19 fue notificado por primera vez en Wuhan (China) el 31 de diciembre de 2019. Debido a los elevados niveles de propagación de la enfermedad el 11 de marzo del 2020 la Organización Mundial de la salud la declara pandemia. Desde entonces se han profundizado las desigualdades e inequidades sociales, producto de las medida...

In this work, we introduce an opto-geometric parameter for the morphologic characterization of cell populations during their early adhesion process. Using measurements for a cell population of the maximal optical phase for each cell and its substrate-contact-surface, we show, experimentally, that a relationship exists between these variables. This...

High-density polyethylene–hydroxyapatite (HDPE–HA) composites with different filler content (5–20 %) were synthesized by in situ ethylene polymerization. Good filler dispersion was observed without formation of agglomerates. Osteoblast cell behavior in HDPE–HA composites was evaluated in terms of adhesion, alkaline phosphatase activity and prolifer...

In the bone tissue, collagen is the most abundant protein, conforming 90% of the organic matrix of this mineralized structure. Different works indicate that in postmenopausal osteoporosis, the early degradation of the bone tissue seems to be due to the presence of bone collagen in a condition of overglycosylation, especially in the trabecular bone....

Bone healing and growth are controlled by the rate of deposition of hydroxyapatite (HA). This process have been so far accredited to the work of osteoblasts, which are attracted by the electrical dipoles produced either by piezo-electricity, due to deformation of the bone, specially the colla-gen in it, or due to outside electrical stimuli. The mai...

Bone healing and growth are controlled by the rate of deposition of hydroxyapatite (HA). This process have been so far accredited to the work of osteoblasts, which are attracted by the electrical dipoles produced either by piezoelectricity, due to deformation of the bone, specially the collagen in it or due to outside electrical stimuli.The main pu...

Bone healing and growth are controlled by the rate of deposition of hydroxyapatite (HA). This process have been so far accredited to the work of osteoblasts, which are attracted by the electrical dipoles produced either by piezoelectricity, due to deformation of the bone, specially the collagen in it, or due to outside electrical stimuli. The main...