Ana Maria Gomez Jaramillo

Ana Maria Gomez Jaramillo
Pontificia Universidad Católica del Ecuador | PUCE · Facultad de Medicina

Doctor of Medicine

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17
Publications
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274
Citations

Publications

Publications (17)
Chapter
In Ecuador, the Ministry of Public Health reported, in 2017, 49,541 cases (from 1984 to 2016) of HIV/AIDS. Sexual transmitted infections (STDs) as a gateway for HIV infection are detected as clinical syndromes due to the lack of access to confirmatory tests in most of the primary healthcare units in Ecuador. In 2011, 355,511 cases were estimated, o...
Article
Full-text available
Background: It is imperative to identify drugs that allow treating symptoms of severe COVID-19. Respiratory failure is the main cause of death in severe COVID-19 patients, and the host inflammatory response at the lungs remains poorly understood. Methods: Therefore, we retrieved data from post-mortem lungs from COVID-19 patients and performed in-de...
Preprint
Full-text available
There is pressing urgency to identify drugs that allow treating COVID-19 patients effectively. Respiratory failure is the leading cause of death in patients with severe COVID-19, and the host inflammatory response at the lungs remains poorly understood. Therefore, we retrieved data from postmortem lungs from COVID-19 patients and performed in-depth...
Article
Full-text available
Background: There is pressing urgency to identify therapeutic targets and drugs that allow treating COVID-19 patients effectively. Methods: We performed in silico analyses of immune system protein interactome network, single-cell RNA sequencing of human tissues, and artificial neural networks to reveal potential therapeutic targets for drug repurpo...
Article
Full-text available
Background Galapgos contributes 0.11% of the HIV cases in all Ecuador. There is a social and biological distinction, especially considering that the islands receive 245,000 tourists/year from all over the world, which also includes sex tourism by the LGTBI community. In 2016, the HIV Clinic project began in the Santa Cruz hospital, as an initiative...
Technical Report
Full-text available
Los pacientes con COVID-19 presentan un riesgo mayor de desarrollar eventos tromboembólicos directamente proporcional a la gravedad de su enfermedad. Todos los pacientes hospitalizados con COVID-19 deber recibir tromboprofilaxis, se prefiere heparinas de bajo peso molecular con las pautas estándar de prescripción. Las dosis de anticoagulante se deb...
Technical Report
Full-text available
Inhibidores de proteasa (IP) Nelfinavir, Darunavir y Danoprevir para tratamiento de la infección por COVID-19 PUNTOS CLAVE ANTECEDENTES N o e x i s t e h a s t a e l momento evidencia científica contundente que soporte el uso de los IP en COVID-19. Los resultados positivos de estudios experimentales en cultivos celulares sugieren utilidad de los IP...
Preprint
There is pressing urgency to better understand the immunological underpinnings of the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus clade 2 (SARS-CoV-2) in order to identify potential therapeutic targets and drugs that allow treating patients effectively. To fill in this gap, we performed in silico...
Preprint
There is pressing urgency to better understand the immunological underpinnings of the coronavirus disease 2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus clade 2 (SARS-CoV-2) in order to identify potential therapeutic targets and drugs that allow treating patients effectively. To fill in this gap, we performed in silico...
Technical Report
Full-text available
Plasma convaleciente en el tratamiento de la infección por COVID-19 PUNTOS CLAVE ANTECEDENTES Actualmente, el plasma convaleciente ha sido usado como terapia compasiva en COVID-19 grave, basado en resultados aparentemente positivos en estudios de series de casos. Los estudios de series de casos sobre el uso de plasma convaleciente aportan datos que...
Book
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La pandemia actual por COVID-19 ha amenazado gravemente a toda la humanidad, es por esto que nos hemos visto en la necesidad de recopilar la información más actualizada y relevante con respecto a esta patología; desde su epidemiología global y nacional, características moleculares del virus, cuadro clínico, métodos de diagnóstico, soporte y seguimi...
Technical Report
Full-text available
No existe ningún tratamiento antiviral efectivo para COVID-19 Ivermectina ha demostrado efectividad contra SARS-CoV y otros virus en modelos in vitro. Ivermectina ha demostrado inhibir el virus SARS-CoV-2 en un modelo in vitro. Existen hasta la fecha aproxi-madamente 4 estudios clínicos en ejecución para evaluar la eficacia y seguridad de la iverme...
Article
Coronaviruses are an extensive family of viruses that can cause disease in both animals and humans. The current classification of coronaviruses recognizes 39 species in 27 subgenera that belong to the family Coronaviridae. From those, at least seven coronaviruses are known to cause respiratory infections in humans. Four of these viruses can cause c...
Technical Report
Full-text available
Interferón en el tratamiento de la infección por COVID-19 PUNTOS CLAVE ANTECEDENTES La investigación científica sobre los tratamientos para COVID-19 por el momento es insuficiente y de baja calidad, por lo que los resultados se encuen-tran pendientes. El Interferón es una molécula biológica que ha sido propuesta como terapia experimental para el CO...
Preprint
Full-text available
Coronaviruses are an extensive family of viruses that can cause disease in both animals and humans. The current classification of coronaviruses recognizes 39 species in 27 subgenera that belong to the family Coronaviridae. From those, at least seven coronaviruses are known to cause respiratory infections in humans. Four of these viruses can cause c...
Technical Report
Full-text available
Lopinavir/Ritonavir (LVP/r) en el tratamiento de la enfermedad por COVID-19 PUNTOS CLAVE ANTECEDENTES Al momento la evidencia científica sugiere que la combina-ción de lopinavir/ritonavir en el tratamiento de pacientes grave-mente enfermos por COVID-19, no acelera la recuperación, no reduce la mortalidad y no reduce la carga viral orofaríngea. La s...
Article
Full-text available
Objectives: The Galápagos provides an important setting to investigate the health impacts of a new drinking water treatment plant (DWTP) in a limited resource environment. We examine how household perceptions and practices affect the relationship between water quality and infections before and after DWTP. Methods: Ethnographic data and self-reporte...

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