Amy Price

Amy Price
University of Oxford | OX

Doctor of Philosophy University of Oxford

About

135
Publications
282,319
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Introduction
Dr. Amy Price in Neurocognitive Rehabilitation and in International Missions before sustaining serious injury and years of rehabilitation. She emerged with a goal to build a bridge between research methods, research involvement and public engagement where the public is trained and empowered to be equal partners in health research. Amy’s experience has shown her that shared knowledge, interdisciplinary collaboration and evidence-based research will shape and develop the future.

Publications

Publications (135)
Article
Full-text available
BACKGROUND The use of public engagement and self-management in online clinical trials is growing with benefits, boundaries and minimal methodological guidance. This analysis explores whether running self-recruited online trials can provide trustworthy and useful answers to research questions. AIM To systematically explore existing self-recruited...
Article
In a recent list-serve, the way forward for evidence-based medicine was discussed. The purpose of this paper was to share the reflections and multiple perspectives discussed in this peer-to-peer encounter and to invite the reader to think with a mind for positive change in the practice of health care. Let us begin with a simple question. What if we...
Article
Intramuscular injection has been used to administer medications for more than a hundred years. However, despite our profession’s long experience with intramuscular administration, preventable complications such as injection nerve palsies are still prevalent in developing countries. Injections account for one-fifth of all traumatic nerve injuries. T...
Article
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To share how an effectual merging of local and online networks in low resource regions can supplement and strengthen the local practice of patient centered care through the use of an online digital infrastructure powered by all stakeholders in healthcare. User Driven Health Care offers the dynamic integration of patient values and evidence based so...
Article
This article explores some of the trials and tribulations the family members of patients with traumatic brain injury go through. In the first part, Jazmin Price recounts her recollections of the accident which changed her grandparents’ lives and the effect which it had on her interactions with them. In the second part of the article, Dr. Amy Price,...
Article
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Background Face shields were widely used in 2020-2021 as facial personal protective equipment (PPE). Laboratory evidence about how protective face shields might be and whether real world user priorities and usage habits conflicted with best practice for maximum possible protection was lacking – especially in limited resource settings. Methods Rela...
Article
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Background Adherence to infection prevention and control (IPC) measures, including the proper use of protective personal equipment (PPE), in health care is complex and is influenced by many factors. Isolated interventions do not have the potential to achieve optimal PPE adherence and appropriate provision, leading to incomplete PPE implementation....
Article
Background: Patient-reported outcome measures (PROMs) and patient-reported experience measures (PREMs) are self-reporting tools that can measure important information about patients, such as health priorities, experience, and perception of outcome. The use of traditional objective measures such as vital signs and lab values can be supplemented wit...
Article
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Introduction: This paper presents 5 cases of neurodegenerative disorders from our tertiary care rural hospital in south India. The purpose of this paper is to generate an emerging common theme by thematic analysis of clinical data from each of these patients. A theme emerged, we identified that there was a common clinical ground in patients with m...
Article
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Rationale, Aims, and Objectives: It is generally believed that evidence from low quality of evidence generate inaccurate estimates about treatment effects more often than evidence from high (certainty) quality evidence (CoE). As a result, we would expect that (a) estimates of effects of health interventions initially based on high CoE change less f...
Preprint
UNSTRUCTURED Introduction The design of Personal Protective Equipment (PPE) may affect well-being and clinical work. PPE as an integrated item may improve usability and increase adherence by health workers (HW) and reduce occupational-acquired diseases. As integrated PPE, a lightweight battery-powered air-purifying respirator (L-PAPR) could be used...
Preprint
BACKGROUND Objective measures such as vital signs and lab values only provide a partial view of a patient’s condition. Patient reported outcome measures (PROMs)1 and Patient reported experience measures (PREMs)1 are subjective reports shared by patients that can help complete this view by filling in gaps that other methods are incapable of assessin...
Article
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Introduction: The purpose of this study is to conduct an overview of Cochrane systematic reviews (SRs) evaluating the effects of maternal positions in childbirth in order to compile existing evidence for relevant research questions that have been addressed by more than one review, to provide a succinct summary of the up-to-date evidence and to ide...
Preprint
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Rationale, aims and objectives 39 Evidence-based medicine (EBM) holds that estimates of effects of health interventions based on 40 high-certainty evidence (CoE) are expected to change less frequently than the effects generated 41 in low CoE studies. However, this foundational principle of EBM has never been empirically 42 tested. 43 Methods 44 We...
Preprint
BACKGROUND Expressing empathy builds trust with patients, increases patient satisfaction and is associated with better health outcomes. Research shows expressing empathy and compassion to patients improves patient adherence to medications, decreases patient anxiety and decreases the number of malpractice lawsuits. Yet, there is a dearth of research...
Article
Background Expressing empathy builds trust with patients, increases patient satisfaction, and is associated with better health outcomes. Research shows that expressing empathy to patients improves patient adherence to medications and decreases patient anxiety and the number of malpractice lawsuits. However, there is a dearth of research on teaching...
Preprint
BACKGROUND Medical education, research, and healthcare practice continue to grow with minimal co-production guidance. We suggest the Commons approach to medical education as modeled by Ostrom and Williamson where we share how adapting these models to multiple settings can enhance empathy, increase psychological safety and provide robust just-in-tim...
Article
Medical education, research, and health care practice continue to grow with minimal coproduction guidance. We suggest the Commons Principle approach to medical education as modeled by Ostrom and Williamson, where we share how adapting these models to multiple settings can enhance empathy, increase psychological safety, and provide robust just-in-ti...
Article
The public and patients can be powerful sensors for shaping and powering healthcare research. They are joining research teams as investigators and collaborators to co-produce evidence for the practical use of interventions in clinical practice. While clinicians and researchers are encouraged by funders and policymakers to involve the public and pat...
Article
Objective The coronavirus disease 2019 (COVID-19) pandemic has resulted in shortages of personal protective equipment (PPE) underscoring the urgent need for simple, efficient, and inexpensive methods to decontaminate SARS-CoV-2-exposed masks and respirators. We hypothesized that methylene blue (MB) photochemical treatment, which has various clinica...
Article
'Blinding' involves concealing knowledge of which trial participants received the interventions from participants themselves and other trial personnel throughout the trial. Blinding reduces bias arising from the beliefs and expectations of these groups. It is agreed that where possible, blinding should be attempted, for example by ensuring that exp...
Article
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The science around the use of masks by the public to impede COVID-19 transmission is advancing rapidly. In this narrative review, we develop an analytical framework to examine mask usage, synthesizing the relevant literature to inform multiple areas: population impact, transmission characteristics, source control, wearer protection, sociological co...
Preprint
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Background The coronavirus disease 2019 (COVID-19) pandemic has resulted in severe shortages of personal protective equipment (PPE) necessary to protect front-line healthcare personnel. These shortages underscore the urgent need for simple, efficient, and inexpensive methods to decontaminate SARS-CoV-2-exposed PPE enabling safe reuse of masks and r...
Preprint
Full-text available
The science around the use of masks by the general public to impede COVID-19 transmission is advancing rapidly. Policymakers need guidance on how masks should be used by the general population to combat the COVID-19 pandemic. In this narrative review, we develop an analytical framework to examine mask usage, considering and synthesizing the relevan...
Article
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Patient-centered organisations Healthcare organisations now integrate patient feedback into value-based compensation formulas. This research considered Stanford Healthcare’s same-day feedback, a programme designed to evaluate the patient experience. Specifically, how did patients with cancer interviewed in the programme assess their physicians? Fur...
Preprint
Full-text available
The science around the use of masks by the general public to impede COVID-19 transmission is advancing rapidly. Policymakers need guidance on how masks should be used by the general population to combat the COVID-19 pandemic. In this narrative review, we develop an analytical framework to examine mask usage, considering and synthesizing the relevan...
Article
Full-text available
Background: Placebo or sham controls are the standard against which the benefits and harms of many active interventions are measured. Whilst the components and the method of their delivery have been shown to affect study outcomes, placebo and sham controls are rarely reported and often not matched to those of the active comparator. This can influe...
Article
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Given the rapidly changing nature of COVID-19, clinicians and policy makers require urgent review and summary of the literature, and synthesis of evidence-based guidelines to inform practice. The WHO advocates for rapid reviews in these circumstances. The purpose of this rapid guideline is to provide recommendations on the organizational management...
Article
Background: Malabsorption and deficiency of fat-soluble vitamins K may occur in cystic fibrosis, a genetic disorder affecting multiple organs. Vitamin K is known to play an important role in both blood coagulation and bone formation, hence the role of supplementation of vitamin K in this category needs to be reviewed. This is an updated version of...
Article
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The COVID-19 pandemic is currently causing a severe disruption and shortage in the global supply chain of necessary personal protective equipment (e.g., N95 respirators). The U.S. CDC recommended use of household cloth by the general public to make cloth face coverings as a method of source control. We evaluated the filtration properties of natural...
Preprint
Full-text available
The science around the use of masks by the general public to impede COVID-19 transmission is advancing rapidly. Policymakers need guidance on how masks should be used by the general population to combat the COVID-19 pandemic. Here,we develop an analytical framework to examine an overlooked aspect of mask usage: masks as source-control targeting egr...
Preprint
Full-text available
The current COVID-19 pandemic has highlighted global supply chain shortcomings in the US hospital delivery system, most notably personal protective equipment (PPE) and COVID-19 is found on these masks ∼7 days. Recent work from our group has shown two promising disinfection methods for N95 facial masks, dry heat (hot air (75 °C, 30 min) and UVGI whi...
Chapter
An overarching framework, describing the elements of patient and family engagement and how to develop interventions, provides a matrix covering the continuum of engagement and illustrating how these can be achieved at different levels of care. This chapter uses this framework to summarize the evidence about the influence of patient engagement on he...
Preprint
Full-text available
The science around the use of masks by the general public to impede COVID-19 transmission is advancing rapidly. Policymakers need guidance on how masks should be used by the general population to combat the COVID-19 pandemic. Here, we synthesize the relevant literature to inform multiple areas: 1) transmission characteristics of COVID-19, 2) filter...
Article
Full-text available
The public brings to the table valuable perspectives learned from living with the health problems research works to solve. Patients as research partners in the clinic, at home, and in the lab can provide the fine details for a successful implementation that differentiate a research finding that sits expensive and unused from primary care that impro...
Article
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Abstract Importance Hypertension is very common, but guideline recommendations for hypertension have been controversial, are of increasing interest, and have profound implications. Objective To systematically assess the consistency of recommendations regarding hypertension management across clinical practice guidelines (CPGs). Design, Setting, an...
Article
Full-text available
Importance: Hypertension is very common, but guideline recommendations for hypertension have been controversial, are of increasing interest, and have profound implications. Objective: To systematically assess the consistency of recommendations regarding hypertension management across clinical practice guidelines (CPGs). Design, Setting, and P...
Article
The clinical significance of aberrantly expressed microRNAs in predicting treatment response to chemotherapy in diffuse large B-cell lymphoma patients (DLBCL) remains uncertain. Feasibility of microRNA testing to predict treatment outcome was evaluated. Twenty-two types of aberrantly expressed microRNAs were associated with poor treatment response;...
Article
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Objective Dissemination of research findings is central to research integrity and promoting discussion of new knowledge and its potential for translation into practice and policy. We investigated the frequency and format of dissemination to trial participants and patient groups. Design Survey of authors of clinical trials indexed in PubMed in 2014...
Article
Background: Poorly described placebo/sham controls inhibit appraisal of active intervention benefits and harms. The 12-item Template for Intervention Description and Replication (TIDieR) checklist was developed to improve the reporting of active intervention components. The extent to which TIDieR is used to guide description of placebo or sham con...
Presentation
Objectives To systematically assess the consistency of recommendations regarding hypertension management across clinical practice guidelines (CPGs) and electronic point-of-care (POC) resources Method We identified hypertension management recommendations from eight CPGs and two POC resources in April 2018. We described discrete and unambiguous spec...
Article
Coronary artery disease managed by percutaneous coronary intervention (PCI) has been noted for profit-driven overuse medicine. Concerns mount over inappropriate use of PCI for patients in India. We describe the case of a 55-year-old Indian man who presented for a second opinion following an urgent recommendation for PCI by two cardiologists followi...
Article
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Although PPI and co-production is an emergent practice, self-management and self-care initiatives in healthcare have reduced costs and increased quality of life. For example, patients remotely manage complex conditions such as diabetes, anti-coagulation therapies, home kidney dialysis, tube feeding, pain pumps, thyroid care and asthma. These inte...
Article
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Alzheimer's disease, the most common form of dementia, is marked by progressive cognitive and functional impairment believed to reflect synaptic and neuronal loss. Recent preclinical data suggests that lipopolysaccharide (LPS)-activated microglia may contribute to the elimination of viable neurons and synapses by promoting a neurotoxic astrocytic p...
Article
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Background: Utility scores are integral to health economics decision-making. Typically, utility scores have not been scored or developed with mental health service users. The aims of this study were to i) collaborate with service users to develop descriptions of five mental health states (psychosis, depression, eating disorder, medication side eff...
Article
Background: The Self-Management Open Online Trials in Health (SMOOTH) survey reports methods as well as researcher preferences in online trials and explores to what extent public and participant involvement in online trials occurs. This survey queried researchers’ experience in online trials and their perceived value in terms of public and patient...
Article
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Objective In 2014/2015, The BMJ and Research Involvement and Engagement (RIE) became the first journals to routinely include patients and the public in the peer review process of journal articles. This survey explores the perspectives and early experiences of these reviewers. Design A cross-sectional survey. Setting and participants Patient and p...
Article
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Objective Many journals permit authors to submit supplementary material for publication alongside the article. We explore the value, use and role of this material in biomedical journal articles from the perspectives of authors, peer reviewers and readers. Design and setting We conducted online surveys (November–December 2016) of corresponding auth...
Article
Background: The growth of trials conducted over the internet has increased, but with little practical guidance for their conduct and it is sometimes challenging for researchers to adapt the conventions used in face-to-face trials and maintain the validity of the work. Aim: To systematically explore existing self-recruited online randomized trial...
Article
Full-text available
Is the needle tip configuration important when performing a lumbar puncture for any indication? A systematic review published in the Lancet in Decem-ber 2017 suggests that it is. The review found that using atraumatic (pencil-point) lumbar puncture needles instead of conventional lumbar puncture needles reduced the risk of post-dural-puncture heada...
Article
Background: In this study, we demonstrate a collective collaborative, conversational, pre-publication peer review of a randomized controlled trial. Methods: Using Critical Appraisal Skills Programme checklist, a group of research-oriented undergraduate medical and pharmacy students and their teacher collectively on an online forum, discuss and re...
Article
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Objectives While documented plans for patient and public involvement (PPI) in research are required in many grant applications, little is known about how frequently PPI occurs in practice. Low levels of reported PPI may mask actual activity due to limited PPI reporting requirements. This research analysed the frequency and types of reported PPI in...
Article
Aging has been associated with iron retention in many cell types, including the neurons, promoting neurodegeneration by ferroptosis. Excess intracellular iron accelerates aging by damaging the DNA and blocking genomic repair systems, a process we define as ferrosenescence. Novel neuroimaging and proteomic techniques have pinpointed indicators of bo...
Article
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O19 Developing resources for a learner-centred approach to learning and development for public involvement in research Lucy Frith1, Bernard Gudgin2, Amander Wellings3 1National Institute for Health Research (NIHR), Research Design Service North West, University of Liverpool, Liverpool, UK; 2Public representative, Thames Valley, UK; 3Public represe...
Article
Background: Funders encourage lay-volunteer inclusion in research. There are controversy and resistance, given concerns of role confusion, exploratory methods, and limited evidence about what value lay-volunteers bring to research. This overview explores these areas. Methods: Eleven databases were searched without date or language restrictions f...
Article
ABSTRACT Introduction :Evidence-based medicine (EBM) introduced in 1991 marks the relationship between medical evidence and clinical practice. In EBM, evidence acts as a neutral arbiter between competing views. EBM enjoys exponential growth on par with innovations such as antibiotics and anesthesia, however it has not escaped external controversy o...