Amy Alexander

Amy Alexander
Mayo Clinic - Rochester · Engineering

BSc, MSc

About

27
Publications
3,819
Reads
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299
Citations
Citations since 2016
27 Research Items
299 Citations
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2016201720182019202020212022020406080100
2016201720182019202020212022020406080100
2016201720182019202020212022020406080100

Publications

Publications (27)
Article
Background: Selection of skull base approaches is a critical skill for complex cranial surgery, which demands nuanced understanding of neuroanatomy and pathology. Objective: To develop novel pedagogical resources for approach selection education and assessment. Methods: A prospectively maintained skull base registry was screened for posterior...
Article
Virtual surgical planning and three-dimensional printing have been invaluable tools in craniomaxillofacial surgery. From planning head and neck reconstruction to orthognathic surgery and secondary reconstruction of maxillofacial trauma, virtual surgical planning and three-dimensional printing allow the surgeon to rehearse the surgical plan and use...
Article
Background Virtual surgical planning (VSP), computer aided design/computer aided modeling (CAD/CAM), and three-dimensional (3D) printing technology have been shown to improve surgical accuracy and efficiency in head and neck reconstruction. However, persisting criticism of the technology is that it does not adequately address the soft-tissue relate...
Chapter
Three-dimensional (3D) printed anatomic models and guides designed from volumetric medical imaging data are used clinically to provide increased comprehension of anatomy, more exact pathology evaluation, and more precise surgical intervention. The technical and professional work that goes into image acquisition, segmentation, computer-aided design,...
Chapter
3D printing has applications in medicine that reach from anatomical and biological education to clinical regenerative medicine. Artists, illustrators, designers, engineers, physicians, and scientists have acknowledged and leveraged the use of additive machines for decades, and rely heavily on the technology to move from concept to prototype to fina...
Article
Importance Maxillectomy can commonly be performed through a transoral approach, but maxillectomy defect reconstruction can be difficult to precisely design, contour, and inset through this approach. Objective To evaluate whether the use of virtual surgical planning (VSP) and 3-dimensional (3-D) modeling is associated with a decrease in the require...
Article
Full-text available
Facial gender confirmation surgery (FGCS) is a powerful set of procedures in the armamentarium of plastic surgeons that can transform the male face into a gender-congruent female face and provide the transgender individual with improved quality of life, positive body image and help in social integration. The goals of the FGCS procedures are to addr...
Article
Background To determine whether virtual surgical planning and three‐dimensional printed cutting guides (3D/VSP) improved radiographic bone union compared to conventional methods (CM) in fibula free flap (FFF) reconstruction of the mandibles. Methods Retrospective study from the years 2000–2018 at a tertiary hospital. Osseous union was evaluated by...
Article
Full-text available
First patented in 1986, three-dimensional (3D) printing, also known as additive manufacturing or rapid prototyping, now encompasses a variety of distinct technology types where material is deposited, joined, or solidified layer by layer to create a physical object from a digital file. As 3D printing technologies continue to evolve, and as more manu...
Article
Background: 3D printing—also known as additive manufacturing—has a wide range of applications. Reproduction of low-cost, high-fidelity, disease- or patient-specific models presents a key developmental area in simulation and education research for complex cranial surgery. Methods: Using cadaveric dissections as source materials, skull base models we...
Article
Full-text available
Background: In recent years, three-dimensional (3D) printing has been increasingly applied to the intracranial vasculature for patient-specific surgical planning, training, education, and research. Unfortunately, though, much of the prior literature regarding 3D printing has focused on the end-product and not the process. In addition, for 3D print...
Article
Subscapular-based flaps have historically maintained an unparalleled ability to provide a multitude of bone and soft tissue components based on a single vascular pedicle. However, these flaps are often not thought of as an ideal choice for composite defects requiring extended lengths of bone for reconstruction. The ability to harvest long segments...
Article
Full-text available
Advanced visualization of medical image data in the form of three-dimensional (3D) printing continues to expand in clinical settings and many hospitals have started to adapt 3D technologies to aid in patient care. It is imperative that radiologists and other medical professionals understand the multi-step process of converting medical imaging data...
Article
Full-text available
Background Abdominal aortic aneurysm (AAA) models can be manufactured with 3D printing technology. This study describes detailed methodology and validation of endovascular aortic repair (EVAR) simulation using 3D printed AAA model connected to hemodynamic pump. Method The AAA model was printed with Objet500 Connex3 (Stratasys, Eden Prairie, MN) an...
Article
Full-text available
PurposeTo determine whether a 3D printed model improves patients’ understanding of renal cryoablation and the involved anatomy. Methods This prospective study included 25 control patients, who received standard of care renal cryoablation education (verbal explanation accompanied by review of relevant 2D imaging) and 25 experimental patients, who re...
Article
Segmental mandibular defects secondary to infectious, traumatic, and pathologic conditions can be debilitating because of their impact on function and facial esthetics. Several reconstructive techniques are available, with vascularized flaps commonly used for the reconstruction of large bony or composite segmental defects. The free fibular flap for...
Article
Virtual surgical planning (VSP), computer aided design (CAD)/computer aided modeling (CAM), and 3D printing are three distinct technologies that have become increasingly employed within head and neck oncology and microvascular reconstruction. While each of these technologies have long been utilized for treatment planning within other surgical disci...
Article
Full-text available
In this work, we provide specific clinical examples to demonstrate basic practical techniques involved in image segmentation, computer-aided design, and 3D printing. A step-by-step approach using United States Food and Drug Administration cleared software is provided to enhance surgical intervention in a patient with a complex superior sulcus tumor...
Article
Full-text available
Background Alzheimer’s disease prevalence will reach epidemic proportions in coming decades. There is a need for impactful educational materials to help patients, families, medical practitioners, and policy makers understand the nature and impact of the disease. Defining an effective workflow to create such models from existing segmentation tools w...
Article
Full-text available
Background The purpose of this study is to provide a framework for the development of a quality assurance (QA) program for use in medical 3D printing applications. An interdisciplinary QA team was built with expertise from all aspects of 3D printing. A systematic QA approach was established to assess the accuracy and precision of each step during t...
Article
Full-text available
Background To assess the impact of metal artifact reduction techniques in 3D printing by evaluating image quality and segmentation time in both phantom and patient studies with dental restorations and/or other metal implants. An acrylic denture apparatus (Kilgore Typodent, Kilgore International, Coldwater, MI) was set in a 20 cm water phantom and s...
Article
The purpose of this study was to use three-dimensional (3-D) printing techniques to construct liver and brain phantoms having realistic pathologies, anatomic structures, and heterogeneous backgrounds. Patient liver and head computed tomography (CT) images were segmented into tissue, vessels, liver lesion, white and gray matter, and cerebrospinal fl...

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