Amit Raj Sharma

Amit Raj Sharma
Arkansas State University - Jonesboro | ASU · Arkansas Biosciences Institute

PhD in Biotechnology Engineering

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10
Publications
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79
Citations

Publications

Publications (10)
Article
Full-text available
HPLC/DAD-based chemical investigation of a coral-associated gliding bacterium of the genus Tenacibaculum yielded three desferrioxamine-class siderophores, designated tenacibactins K ( 1 ), L ( 2 ), and M ( 3 ). Their chemical structures, comprising repeated cadaverine–succinic acid motifs terminated by a hydroxamic acid functionality, were elucidat...
Article
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Chemical investigation of secondary metabolites from a marine-derived actinomycete strain of the genus Kocuria, isolated from a stony coral Mycedium sp., led to the identification of two new alkanoylimidazoles, nocarimidazoles C (1) and D (2) as well as three known congeners, nocarimidazoles A (3) and B (4) and bulbimidazole A (5). Structure analys...
Article
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A pair of geometrically isomeric unsaturated keto fatty acids, (6 E ,8 Z )- and (6 E ,8 E )-5-oxo-6,8-tetradecadienoic acids ( 1 and 2 ), were isolated from the culture broth of an actinomycete of the genus Micrococcus , which was associated with a stony coral, Catalaphyllia sp. Their chemical structures were elucidated by spectroscopic analysis in...
Article
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(2Z,4E)-3-Methyl-2,4-decadienoic acid (1) was identified as a major metabolite from a culture extract of a marine bacterium Microbulbifer which was collected from a stony coral Porites sp. NMR-based spectroscopic analysis revealed that 1 is an unsaturated fatty acid in which a methyl group is located in an uncommon position as a natural product. Fe...
Article
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A new catecholate-containing siderophore, labrenzbactin (1), was isolated from the fermentation broth of a coral-associated bacterium Labrenzia sp. The structure and absolute configuration of 1 was determined by spectroscopic methods and Marfey’s analysis. Overall, 1 showed antimicrobial activity against Ralstonia solanacearum SUPP1541 and Micrococ...
Article
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Multidrug resistant (MDR) infections have been a world health issue for many decades, and therefore exploration of new antibiotics to overcome this issue is urgently needed. Regarding antimicrobial properties in the coral holobiont, coral-associated bacteria are suggested as potential producer of new antibacterial agents against MDR infections. The...
Article
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A wound is any physical injury involving a break in the skin, and exposed subcutaneous tissues provide a favorable substratum for a wide variety of microorganisms to contaminate and colonize. In this study a total of 870 plus samples were collected from patients visiting B & B hospital suspecting wound infection and then analyzed. The causative age...
Article
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Antibiotic resistance among uropathogens is emerging public health problem. This study was done for assessingantibiotic and multidrug resistance (MDR) patterns of Escherichia coli at Bir Hospital, Kathmandu, among suspectedurinary tract infection (UTI) patients from January to March, 2011. Altogether, 739 urine samples were analysed bysemi-quantita...
Article
Full-text available
Naturally occurring arsenic (As) in groundwater of sedimentary aquifer has emerged as a global problem, and issue of major environmental health concern. Most groundwater from the Terai Basin of Nepal is contaminated by excess arsenic. Such groundwater is widely used for drinking and irrigation purpose and makes easy means of direct entrance of arse...

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