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Publications (13)
Objectives: This study employed computational fluid dynamics (CFD), physiologically based toxicokinetics (PBTK), and statistical modeling to reconstruct exposure to methylene diphenyl-4,4'-diisocyanate (MDI) aerosol. By utilizing a validated CFD model, human respiratory deposition of MDI aerosol in different workload conditions was investigated, wh...
Background
Noise-induced hearing loss (NIHL) is one the major causes of acquired hearing loss in developed countries. Noise can change the pattern of gene expression, inducing sensorineural hearing impairment. There is no investigation on the effects of noise frequency on the expression of GJB2 and SLC26A4 genes involved in congenital hearing impai...
Background
Noise, a physical factor in most work environments, has many effects on human health. Exposure to excessive noise can modify the expression of associated genes with NIHL. The aim of this study to elucidate changes in expression of GJB2 and SLC26A4 after exposure to intense noise which are the most frequent causing genes to apparent autos...
Introduction: One of the most important complications of exposure to noises is changes in the gene expression patterns. Irreversible damage to the inner ear, such as noise-induced hearing loss (NIHL), is caused by tissue damage and changes in the gene expressions in the auditory system. Changes in the GJB2 gene expression pattern lead to autosomal...
Background: The purpose of the present study is to investigate the effect of one session of exhaustive activity with supplementation of beta-alanine on the level of carnosine and muscle strength of upper and lower extremities of bodybuilding athletes.
Materials and Methods: Twenty bodybuilders were randomly divided into two equal groups of 10 who w...
Noise can change the pattern of gene expression inducing sensorineural hearing impairment. There is no investigation on effects of noise frequency on the expression of GJB2 and SLC26A4 genes involved in congenital hearing impairment in cochlear tissue. This study investigated impacts of white and purple noise on gene expression and pathologic chang...
Background and Aims: As one of the most important physical detrimental factors, purple noise can be considered similar to sounds that a wide range of people are exposed to in their workplaces. Also, cochlear tissue samples are the best tissue samples to evaluate gene expression and pathologic studies following noise exposure. Therefore, the aim of...
