Amer N Kadri

Amer N Kadri
Main Line Health | MLH

MD

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75
Publications
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473
Citations

Publications

Publications (75)
Article
Full-text available
Background Syncope accounts for 0.6% to 1.5% of hospitalizations in the United States. We sought to determine the causes and predictors of 30‐day readmission in patients with syncope. Methods and Results We identified 323 250 encounters with a primary diagnosis of syncope/collapse in the 2013–2014 Nationwide Readmissions Database. We excluded pati...
Article
Objectives A substantial number of patients with severe tricuspid regurgitation (TR) and congestive heart failure (CHF) are medically managed without undergoing corrective surgery. We sought to assess the characteristics and outcomes of CHF patients who underwent tricuspid valve surgery (TVS), compared with those who did not. Methods Retrospective...
Article
Objectives: The aim of this study was to compare outcomes after transcatheter aortic valve replacement (TAVR) in patients with pure aortic stenosis (AS) (i.e., no or trivial associated aortic regurgitation [AR]) with those in patients with AS and mild or more severe AR (i.e., mixed aortic valve disease [MAVD]). Background: TAVR is indicated in t...
Article
Background Patients with aortic stenosis (AS) and malignancy experience poor clinical outcomes with challenging decisions regarding aortic valve replacement (AVR). We sought to compare the outcomes of transcatheter (TAVR) versus surgical (SAVR) AVR in patients with AS and malignancy. Methods Based on the Nationwide Readmission Database, we compare...
Article
Full-text available
Background There has been an increase in the prevalence of drug abuse ( DA ) in the national opioid epidemic. With increasing DA , there is an increased risk of infective endocarditis ( IE ). There are limited recent data evaluating national trends on the incidence and geographical distribution of DA ‐ IE . We aim to investigate those numbers as we...
Article
Full-text available
Acute pulmonary embolism (PE) may manifest with mild nonspecific symptoms or progress to a more severe hemodynamic collapse and sudden cardiac arrest. A substantial thrombotic burden can precipitate sudden right ventricular strain and failure. Traditionally, systemic thrombolytics have been employed in such scenarios; however, patients often presen...
Article
Background: Heart failure with mildly-reduced ejection fraction (HFmrEF) of 40-49% is an under-recognized type of heart failure. The prognosis and predictors of outcomes of stable mildly-reduced ejection fraction (EF) of one year are unclear. Methods: This is a retrospective study. Included patients had stable left ventricular ejection fraction...
Article
Background: New-onset left bundle branch block (LBBB) can develop after transcatheter aortic valve replacement (TAVR) resulting in worse outcomes. Aims: Describe clinical and echocardiographic outcomes with new-onset LBBB after TAVR. Methods: We included consecutive patients who underwent transfemoral-TAVR with SAPIEN-3 (S3) valve between Apri...
Article
Background Transcatheter aortic valve replacement (TAVR) is an alternative therapeutic modality to surgical aortic valve replacement (SAVR) in patients with severe aortic stenosis (AS). In the current analysis, we compare the characteristics and outcomes of AVR procedures in patients <60 years of age. Methods We queried the Nationwide Readmissions...
Article
Full-text available
Background New left bundle branch block (LBBB) is a common finding after transcatheter aortic valve replacement (TAVR) that can result in worse outcomes after TAVR. We aim to investigate the impact of new-onset LBBB after TAVR using the SAPIEN-3 (S3) valve. Methods Consecutive patients who underwent transfemoral-TAVR with S3 valve between April 20...
Article
Background: Acute coronary syndrome (ACS) is affected by several weather conditions. Studies from different geographical locations have yielded mixed results regarding the outcomes of patients presenting with ACS during snowy days, and we aim to report the Cleveland Clinic experience. Methods: Patients who presented with an ACS and underwent per...
Article
Full-text available
Background Concerns about discordance between echocardiographic and invasive mean gradients after transcatheter aortic valve replacement (TAVR) with balloon‐expandable valves (BEVs) versus self‐expanding valves (SEVs) exist. Methods and Results In a multicenter study, direct‐invasive and echocardiography‐derived transvalvular mean gradients obtain...
Conference Paper
Full-text available
Background ❑ New left bundle branch block (LBBB) is a common finding after transcatheter aortic valve replacement (TAVR) that can result in worse outcomes after TAVR. We aim to investigate the impact of new-onset LBBB after TAVR using the SAPIEN-3 (S3) valve. Methods: ❑ Consecutive patients who underwent transfemoral-TAVR with S3 valve between Apr...
Article
Full-text available
Objectives: To compare echocardiographic and invasive mean gradients obtained concomitantly in degenerated bioprosthetic surgical aortic valves (SAVRs). Methods: In a multicenter study, we compared concomitant echocardiographic and invasive mean gradients of SAVR, obtained before valve-in-valve transcatheter aortic valve replacement in all patie...
Article
Objectives Pneumothorax (PTX) in newborns is a life‐threatening condition associated with high morbidity and mortality especially in premature infants. The frequency of PTX in neonates at different gestational ages (GA) and its impact on neonatal mortality have not been quantified. We aimed to determine: (1) the prevalence of PTX in neonates at dif...
Preprint
Objectives: Pneumothorax (PTX) in newborns is a life-threatening condition associated with high morbidity and mortality especially in premature infants. The frequency of PTX in neonates at different gestational ages (GA) and its impact on neonatal mortality have not been quantified. We aimed to determine: 1) the prevalence of PTX in neonates at dif...
Article
Background: There has been an explosion in the clinical application of transcatheter aortic valve replacement (TAVR) worldwide. While moderate and severe grades of paravalvular regurgitation (PVR) are established as poor prognostic indicators, the impact of mild PVR is unclear. To compare outcomes after TAVR between those who develop mild PVR vers...
Article
Objectives: Obesity and cardiovascular disease remain significant burdens on the overall provision of health care in the United States. Obesity has been shown to be a direct risk factor for heart failure (HF). We conducted a nationwide cohort study to assess the short-term impact of obesity in hospitalized patients with HF. Methods: We identifie...
Article
Background Acute myocardial infarction (AMI) is a significant health and economic burden in the US. Tobacco, alcohol, and drug use are established risk factors. We sought to evaluate the national trend of use of each substance in patients admitted with AMI. Methods We used the National Inpatient Sample between 2005 and 2017. We included adult pati...
Article
Background Transcatheter aortic valve replacement (TAVR) has become the mainstay in the treatment of patients with severe calcific aortic stenosis. However, little is known about the outcomes of TAVR in transplant recipients. Methods Patients who underwent TAVR and transplant were compared to a control group of TAVR patients who did not have a tra...
Article
Background Transcatheter aortic valves are prone to acute recoil similar to the metal‐based coronary stents. However, it is not clear if recoil remains a factor only after the initial valve deployment or also after post‐dilation. Methods We conducted a retrospective observational study of patients who underwent transfemoral transcatheter aortic va...
Article
Objectives The aim of this study was to determine the utility of rapid atrial pacing immediately after transcatheter aortic valve replacement (TAVR) to predict the need for permanent pacemaker implantation (PPI). Background Risk stratification for patients without high-grade atrioventricular block (AVB) after TAVR is imprecise and based on anatomi...
Article
Full-text available
Background: Seizures are the most frequent neurological manifestation in neonates. Prevalence of neonatal seizures has not been well described in relationship with gestational age (GA). Also, the impact of seizures on neonatal mortality has not been quantified. This study aims to determine 1) prevalence of neonatal seizures in all GA groups, 2) as...
Article
Objectives: The aim of this study was to compare the rate and trend of vascular complications when placing a second arterial sheath in the contralateral femoral artery during transcatheter aortic valve replacement (TAVR) unilaterally versus bilaterally. Background: Vascular complications occur in approximately 5% to 8% of TAVR procedures. Many o...
Article
Aims: The Pulmonary Embolism in Syncope Italian Trial reported 17.3% prevalence of pulmonary embolism (PE) in patients admitted with syncope. We investigated the prevalence of venous thromboembolism [VTE, including PE and deep vein thrombosis (DVT)] in syncope vs. non-syncope admissions and readmissions, and if syncope is an independent predictor...
Article
Concomitant heart failure (HF) and mitral valve disease (MVD) portend significant morbidity and mortality. Although associated Tricuspid regurgitation (TR) is a common occurrence in this scenario, it is not well known whether there are additional prognostic implications. We sought to assess whether coexistent TR is associated with higher readmissio...
Article
Survival rates of patients with non‐Hodgkin lymphoma (NHL) have improved over the last decade. However, cardiotoxicities remain important adverse consequences of treatment with chemotherapy and radiation, although the burden of cardiovascular mortality (CVM) in such patients remains unknown. We conducted a retrospective cohort study of patients ≥20...
Article
Full-text available
Complete heart block (CHB) is an unfortunate complication of an anterior and inferior myocardial infarction (MI). We present a case of an atherosclerotic occlusion of the first septal perforator leading to CHB requiring permanent pacemaker placement in a young patient. A 33-year-old healthy white male presented to the emergency department with an e...
Article
Full-text available
Acute aortic dissection is a deadly disease that should be recognized promptly. We report an exceptional case of a 44-year-old African American female who presented with a rapidly progressing severe frontal headache. Initial computed tomography of the brain was negative. The following day, she developed uncontrolled hypertension and worsening heada...
Data
Table S1. ICD‐9 Comorbidities and Causes of Readmission
Article
Full-text available
Introduction Chronic kidney disease (CKD) and congestive heart failure (CHF) patients have higher serum B-type natriuretic peptide (BNP), which alters the test interpretation. We aim to define BNP cutoff levels to diagnose acute decompensated heart failure (ADHF) in CKD according to CHF subtype: heart failure with preserved ejection fraction (HFpEF...
Article
Background: Neurocardiogenic syncope (NCS) is a common form of syncope. Although selective serotonin reuptake inhibitors and other medications have been used to treat NCS with variable success, there is no consensus regarding a first-line therapy. Study question: To assess the effects of citalopram in NCS and to examine the effect of diagnostic...
Poster
This meta-analysis demonstrates the effectiveness of exercise training in POTS by symptoms improvement and HR reduction.

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