Amar Hamrouni

Al Ain University · Department of Pharmacy

Background: There is a paucity of studies describing the risk factors for developing ischemic stroke in our region. Objective: The objective of the current study was to delineate the potential risk factors for the development of ischemic stroke. Methods: We have conducted a retrospective cohort hospital-based study that has enrolled 231 subjects. T...

Background: Since the declaration of the COVID-19 pandemic, the United Arab Emirates (UAE) government has taken a series of preventive measures to control the spread of the Coronavirus. Dealing with the unforeseen challenges caused by the pandemic has had a profound impact on people all around the world. Pharmacists played an important public heal...

Amar M Hamrouni,1 Rubian S Sharif,2 Suleiman I Sharif,3 Mohammed M Hassanein,3 Abduelmula R Abduelkarem3 1Department of Pharmaceutical Sciences, College of Pharmacy, Al Ain University, Al Ain, United Arab Emirates; 2Faculty of Dentistry, University of Benghazi, Benghazi, Libya; 3Department of Pharmacy Practice & Pharmacotherapeutics, College of Pha...

Objective The aim of this study was to develop a risk prediction model for non-adherence to prescribed medication based on self-reported risk factors in patients with the acute coronary syndrome (ACS). Methods This is a prospective follow-up cohort study of 210 patients with ACS at a tertiary hospital in Al Ain city in the United Arab Emirates. Pa...

Coronaviruses are non-segmented and single stranded positive-sense RNA (+ssRNA) viruses. To date, 06 human coronaviruses (HCoVs) are reported; a-CoVs (HCoVs-NL63 and HCoVs-229E) and b-CoVs (HCoVs-OC43, HCoVs-HKU1, SARS-CoV, MERS-CoV). While, novel coronavirus (SARS-CoV-2) is the most recent member. The genome sequence of SARS-CoV-2 is 82% similar t...

Background The most prevalent nutritional disorders worldwide are childhood overweight or obesity. Various factors clearly contribute to the childhood obesity epidemic. The aim of this study is to investigate the prevalence of childhood obesity in children of primary schools, and determine the influence of eating behavior and lifestyle in such a co...

Background: Osteoporosis is a worldwide disease, which is characterized by a reduction in bone mass and alteration of its architecture that increases bone fragility and the risk of fracture. Objective: This study aimed to assess knowledge and attitudes towards osteoporosis of undergraduate medical students in Libya. Methods: A cross sectional-based...

Objective: Students decision to choose pharmacy as a future career is one of many difficult choices, they have to make as they enter the university, and it is a big decision as they have to live with the consequences the rest of their lives. Aim: The purposes of this study were to evaluate the student’s reasons for selecting to study pharmacy major...

Recent studies have shown that many types of mushrooms may have important physiological functions in humans including antioxidant activities, regulation of blood lipid level and blood glucose level. The present study was designed to investigate the antihyperglycemic effect of ethanolic Terfezia boudieri Chatin (TBC) extract on streptozotocin (STZ)...

In this study, target compounds 5-12 were synthesized via acid amine coupling of ibuprofen and naproxen with methyl ester derivatives of amino acids, namely, l-proline, sarcosine, l-tyrosine, and l-glutamic acid. When tested for anti-inflammatory activity using the acute carrageenan-induced hind paw method in rats, compounds 5-12 showed significant...

A series of 1-[(benzofuran-2-yl) phenylmethyl] imidazoles have been evaluated as inhibitors of microsomal 17α-hydroxylase: 17, 20-lyase (P450 17) from rat and human testes, and bovine adrenals.Ketoconazole has 110-fold selectivity for the human enzyme. This selectivity was mirrored in several equipotent imidazole derivatives. Some compounds, althou...

The aim of this study was to identify nationals at risk of developing type 2 diabetes within the next 10 years in some areas across Tripoli Health Authority in Libya. In this questionnaire-based survey, a total of 400 Libyan nationals of both genders were randomly selected from seven areas across the central area of Tripoli Health Authority (Soug E...

Two approaches to tetrahydro-[1H]-2-benzazepin-4-ones of interest as potentially selective, muscarinic (M(3)) receptor antagonists have been developed. Base promoted addition of 2-(tert-butoxycarbonylamino)methyl-1,3-dithiane with 2-(tert-butyldimethylsiloxymethyl)benzyl chloride gave the corresponding 2,2-dialkylated 1,3-dithiane which was taken t...

1 Relaxation responses of the rat isolated duodenum to the putative M1 muscarinic receptor agonist, McN-A-343, were examined to determine whether the response was due to the release of known non-adrenergic, non-cholinergic relaxant neurotransmitters and to establish the involvement of M1 muscarinic receptors. 2 The role of ATP was examined with the...