Amany Abdelaziz

• Master of Pharmacy
• Deraya University

A spectrofluorimetric approach that is sensitive, simple, validated, and cost-effective has been proposed for the estimation of amlodipine (AML) and perindopril (PER) in their bulk powders, pharmaceutical formulations, and spiked human plasma. The recommended approach utilized the quantitative quenching effect of the two cited drugs on the fluoresc...

Where simple, accurate, precise and rapid spectrophotometric method was developed for the assessment of mometasone furoate (MF) and tolnaftate (TF) in pure form and pharmaceutical preparations. These methods depend on the interaction between cited drugs with eriochrome black T (EBT), methyl orange (MO) and Chrome azurol S (CRS) in acidic buffers...

An inexpensive, simple, sensitive and validated approach is developed for estimation of fingolimod through production of colored charge transfer complexes of fingolimod with different electron acceptor reagents, including a reaction of fingolimod as n-donor with 7,7,8,8-tetracyanoquinodimethane, tetrachloro 1,4-benzoquinone and tetracyanoethylene a...

Bevacizumab (BVC) is commonly co-administered with 5-fluorouracil (FLO) as a highly successful treatment for colon cancer. In this study, two spectrofluorimetric techniques were combined to provide an approach for concurrent quantification of BVC and FLO that is very sensitive, quick, easy and accurate. The inclusion of Tween-80 micellar system inc...

A recent antineoplastic medication is pemetrexed, this medicine is now being developed and produced on a large scale, thus approaches for quality control are urgently needed. Spectrofluorimetric guidelines for the simple estimation of pemetrexed were validated. Pemetrexed's assay was depends on observations of its native fluorescence at 275/450 nm...

A simple, new, green, and sensitive approach was established and validated for assay of the recently approved antineoplastic medication; darolutamide (DAR) in its authentic form, pharmaceutical formulation, and biological fluids fluorimetrically. This experiment relied on the native fluorescence of the cited drug and detects the ideal solvent utili...

For quantitation of amlodipine (AML) and perindopril (PER) in their authentic, pharmaceutical formulations and spiked human plasma, a simple, sensitive, validated and inexpensive spectrofluorimetric method has been developed. The proposed method is developed to be based on quantitative quenching effect of two antihypertensive drugs on Eosin Y's nat...

A comparative study for the validation and advancement of two analytical approaches applied for the simultaneous determination of Mometasone Furoate (MF), Miconazole Nitrate (MIC) and Gentamicin (GM) formulated in Momenta ® cream. The first approach was TLC-spectrodensitometric method, which was advanced by separating the three components on TLC al...

A comparative study for the validation of two analytical approaches applied for the simultaneous determination of betamethasone valerate (BV), tolnaftate (TF), gentamicin (GM), and clioquinol (CQ) formulated in mixderm ® cream. The first approach was TLC-spectrodensitometric method, which was advanced by separating the four components on TLC alumin...

TLC-spectrodensitometric method was developed and validated for the simultaneous determination of policresulen (POL) and cinchocainehydrochloride (CIN). The method is being separated on TLC aluminum plates coated with silica gel 60 F 254 , using chloroform : methanol : ammonia (9.5:0.6:1.0, v/v/v)as a mobile phase and Dragendorff reagent as spot de...