Amanpreet Sethi

All India Institute of Medical Sciences | AIIMS · Department of Paediatrics

Objective To determine the macronutrient and energy content of preterm mothers’ milk in our tertiary care center for planning optimum nutrition strategies. Methodology This prospective observational study evaluated the macronutrient and energy contents of preterm mother’s milk. The breast milk composition of 50 mothers was analyzed on 3±2, 7±2, 14...

Purpose To study the features of “nontype 1” retinopathy of prematurity (ROP) and indications of treatment. Design Retrospective study. Methods Medical records of inborn or outborn neonates screened for ROP from tertiary level special newborn care unit according to national screening guidelines were analyzed. Infants diagnosed with milder than ty...

Background: A quality improvement (QI) project was planned to improve the mean duration of Kangaroo mother care (KMC) from 2 hours to 6 hours per week in very preterm infants over a period of 8 weeks in our special newborn care unit (SNCU). Methods: We enrolled stable preterm infant-mother dyads with gestational age <32 weeks and SNCU stay for at l...

Pilot data on Hand hygiene (HH) compliance using a standard World Health Organisation checklist for 1-week suggested only 20% compliance. So, we planned a Quality Improvement study to improve HH compliance among health care providers in our Special Newborn Care Unit from 20% to 60% over 12 months. Methods: We did this study in 3 phases: Baseline...

Haemoglobinopathies are characterised by structurally abnormal haemoglobin variants of the normal adult haemoglobin (HbA) which led to increase hemolysis and dependency on blood transfusion for maintaining normal range hemoglobin. HbD is characterized by point mutation of Glu→Gln substitution at codon 121 with a GAA→CAA change at the DNA level on c...

Objective: To study the Stretched Penile Length (SPL) and Testicular Volume (TV) in newborns and to analyze their correlation with various anthropometric parameters in newborns with gestational age between 32-42 completed weeks. Study Design: Descriptive study Settings: Tertiary care centre in Faridkot, Punjab, India. Participants: 800 newborns wer...

Objective To describe an innovative interactive e-learning method to disseminate knowledge to larger group of participants over a wide geographical area. Methods The course material included standard training tool “Best Practices in Preterm Care,” hosted on Telegram, a cloud-based instant messaging platform. The participants were enrolled in the g...

Background: Pediatric Risk of Mortality (PRISM) III score is one of the widely used scoring systems to quantify critical illness in the pediatric age group. This study was carried out to find the association of PRISM III score with the outcome (discharge/mortality) and also hospital stay in survivors and nonsurvivors. Setting: The study was cond...

To compare the efficacy of low dose fentanyl infusion and 24% oral sucrose in providing optimal pain relief during laser for retinopathy of prematurity (ROP), we enrolled fifty-eight spontaneously breathing preterm infants undergoing laser. The preterm infants were randomized to either fentanyl infusion (1 mcg/kg/hr) or 24% oral sucrose (2 ml). We...

Mother is the major source of minerals in foetal life with placenta actively transporting against a concentration and electrochemical gradient. The foetal serum mineral concentration is thereby higher as compared to maternal values, which possibly help in its rapid accretion in developing bones and for counteracting postnatal fall in calcium levels...

Background: Availability of mothers only milk (MOM) for preterm infants is a boon for their growth and development. Authors found that in our Special Newborn Care Unit (SNCU), the availability of MOM was very less with excessive use of formula feed. So, authors planned a quality improvement (QI) study to improve availability of MOM for preterms in...

Objective To compare the prevalence of vitamin K deficiency after intramuscular vitamin K or no treatment in neonates with sepsis on prolonged (>7 days) antibiotic therapy. Study Design Open label randomized controlled trial. Setting Level 3 Neonatal Intensive Care Unit (NICU). Participants Neonates with first episode of sepsis on antibiotics fo...

Chronic oligohydramnios due to any cause can have grave foetal prognosis. One of the rare complications is Potter‘s sequence which occurs as a result of intrauterine mechanical compression of the foetus due to decreased liquor volume. This case report aims to give an insight into this rare complication. Classical Potter‘s sequence is due to renal c...

Congenital chylothorax (CC) is a rare entity in neonatal period requiring multimodal management strategies. Despite optimum treatment, some cases remain refractory posing significant challenge to the treating physician. We here describe a 33-week preterm neonate presenting with refractory congenital chylothorax who needed treatment with combination...

Quality improvement (QI) in healthcare involves implementing small iterative changes by a team of people using a simple structured framework to resolve problems, improve systems, and to improve patient outcomes. These efforts are especially important in a resource-limited setting where infrastructure, staff and funds are meagre. The concept of QI o...

Collodion baby is a rare congenital disorder of skin characterized by the presence of extra covering of tough film like membrane which breaks on stretching leading to fissure formation. This condition makes the new-born prone to dehydration, electrolyte imbalance, sepsis and temperature instability leading to frequent complications and high mortali...

Most neonatal deaths worldwide occur in low- and middle-income countries (LMICs). Respiratory distress is an important cause of neonatal morbidity and mortality. The epidemiology of respiratory distress among term neonates who constitute the vast majority of births is under reported. The scarcely available data from LMICs suggest an incidence of 1....

This study is a single center quality improvement (QI) initiative in a tertiary care neonatal intensive care unit which was done with an objective to increase the proportion of neonates receiving mother’s own milk (at postnatal age of 7 d) from the current rate of 12.5% to 30% over a period of six weeks. Additional objectives were to evaluate the p...

Heme oxygenase-1 (HO-1) is a rate-limiting enzyme in bilirubin metabolism, and its genetic variant may modulate hyperbilirubinemia risk in neonates. The aim of the present study was to assess the association between heme oxygenase-1 gene variants and hyperbilirubinemia risk in Indian newborns. In a prospective case-control study, we analyzed (GT)n...