Amanda Cox

• Doctor of Medicine
• Associate Professor at Icahn School of Medicine at Mount Sinai

The diagnosis and management of food allergy is complicated by an abundance of homologous, cross-reactive proteins in edible foods and aeroallergens. This results in patients having allergic sensitization (positive tests) to many biologically related foods. However, many are sensitized to foods without exhibiting clinical reactivity. Although molec...

Foods can induce adverse reactions by a variety of mechanisms. An understanding of the characteristic signs and symptoms and the related mechanisms of adverse food reactions allows the clinician to efficiently diagnose and treat patients. Adverse reactions to foods can be classified based on whether there is a nonimmunologic or immunologic basis fo...

Purpose of Review This review incorporates findings from studies of oral food challenges (OFC) over the last decade and highlights the latest innovations and understanding of the procedure. Recent Findings PRACTALL guidelines are widely used in OFC research, but there is still no international consensus on the OFC protocol in clinical practice. Gu...

1. On the basis of some research evidence, as well as consensus, the World Health Organization growth charts should be used to track a child's growth from 0 to 24 months; the Centers for Disease Control and Prevention growth charts should still be used for children 2 years of age and older. (1) 2. On the basis of strong research evidence, exclusive...

This chapter discusses the background, diagnosis, treatment, and prognosis for acute urticaria. Urticaria is characterized by skin findings of spontaneously erupting, pruritic, short-lived wheals (or hives), which may be caused by a variety of triggers or may be idiopathic, and may be associated with angioedema. Acute urticaria refers specifically...

This chapter discusses the background, diagnosis, treatment, and prognosis for allergic diseases of the eye. Ocular allergic diseases are multifactorial allergic inflammatory disorders of the ocular surface that affect the conjunctiva (the mucous membrane lining the anterior sclera and inner eyelid surfaces), eyelids, and the cornea. Ocular allergy...

This chapter discusses the background, diagnosis, treatment, and prognosis for mastocytosis. Mastocytosis is a primary mast cell disorder in which there is an abnormal accumulation of tissue mast cells in one or more organ systems. There are several subtypes of mastocytosis, and classification of mastocytosis is based on the tissues and cell-lines...

As food allergy increases, more research is devoted to its influence on patient and family mental health and quality of life (QoL). This article discusses the effects on parent and child QoL, as well as distress, while appraising the limitations of knowledge given the methods used. Topics include whether QoL and distress are affected compared with...

This letter reports the largest series of open oral food challenges in the literature to date. It describes the feasibility and utility of oral food challenge, further justifying its use in the everyday practice of allergy.

RATIONALE: We report a case of a child with Ataxia-Telangiectasia (AT) diagnosed after adenoidectomy. Ataxia-Telangiectasia is a rare autosomal recessive disorder associated with cerebellar ataxia, ocular and cutaneous telangiectasia, immunodeficiencies (combined immunodeficiencies-70%; thymus hypoplasia; IgG2 and 4, IgA and IgE deficiency), predis...