Research Items (3)
Background: Polycystic ovarian syndrome (PCOS) is the most endocrine disorder common effect (5-10) % in women at reproductive age. Thyroid dysfunction with PCOS is both representing parts of the endocrine system; this link leads to problems of ovulation and pregnancy. Aims: to investigate the prevalence of thyroid disorder in PCOS woman, and associate the outcome with obesity. Patient and method: This study was conducted in Al-batol Teaching Hospital in Baquba City /Iraq. The results reviewed included 63 women: 45 PCOS were diagnosed on the basis of Rotterdam criteria, 18 as control, aged 17- 44 year. The samples have been collected at second day of menstrual cycle, to test fT3, fT4, fTSH in serum. Information was collected for (Age, BMI, LH, and FSH) to be part of this study. Results: A significant increasing in fT3 was found in PCOS women comparison with control pvalue>0.05. T3 showed in significant differences between lean PCOS matched against control Pvalue < 0.05, along with statistically increasing of TSH level in (lean, overweight) PCOS comparison with control pvalue˂0.05. Conclusion: PCOS is associated with hypothyroidism. Obesity or overweight is a key factor leads to increased risk of thyroid disorder.
The research aims to find out the relationship between level of prostate specific antigen (PSA) and BMI In diabetic men, in different age groups .So this work raises questions and hypotheses concerning the role of BMI in rick factor of cancer of prostate in diabetic subjects. The current study included 75 men into three age groups ,first group with age (20-35) years include 21 subjects. Second group men with aged(35-50) years include 26 subject and third group with aged(50-70) include 28 subjects. concentration of PSA was quantitatively determined in subjects by ELISA test. A higher incidence of serum PSA was found in control than diabetic patients. This indicate that the presence of total PSA in sera of diabetic patients may be used as a favorable prognostic indicators and diagnostic tool in prostat tumors. Lower PSA levels are associated with an increased risk of T2DM. This is also true when the obesity is considered, and most of elderly obese (patients and controls) showed a decreased level of serum PSA.