Alseny Yarie Camara

Centre National de formation et de recherche en santé rurale de Maferinyah · Recherche

Introduction The composite coverage index (CCI) is the weighted average coverage of eight preventive and curative interventions received along the maternal and childcare continuum. This study aimed to analyse maternal and child health indicators using CCI. Methods We performed a secondary analysis of demographic and health surveys (DHS) focused on...

Vaccination remains the primary strategy for ending the COVID-19 pandemic. However, vaccination rates are still low in low-income countries. The primary goal of this study was to describe the status of COVID-19 vaccine acceptance and hesitancy among women in Guinea and to identify associated predictors. We conducted a cross-sectional study in five...

Background: Questions remain concerning the rapidity of immune responses and the durability and safety of vaccines used to prevent Zaire Ebola virus disease. Methods: We conducted two randomized, placebo-controlled trials - one involving adults and one involving children - to evaluate the safety and immune responses of three vaccine regimens aga...

Background Despite its effectiveness, the optimal use of the combination of insecticide-treated nets (ITN) and intermittent preventive treatment during pregnancy with sulfadoxine–pyrimethamine (IPTp-SP) remains low in malaria-endemic areas. Therefore, this study analyzed its variations and predictors in Guinea. Methods This study was a secondary a...

Introduction The composite coverage index (CCI) is the weighted average coverage of eight preventive and curative interventions received along the maternal and child care continuum. We analysed maternally and child health indicators using CCI. Methods We performed a secondary analysis of demographic and health surveys (DHS) focused on women aged 15...

Introduction Despite its effectiveness, the optimal use of the combination of insecticide treated nets (ITN) and intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (TPIg-SP) remains low in malaria endemic areas. Therefore, we studied its variations and predictors in Guinea.Methods We conducted a secondary analysis of...

In this case report, we describe a clinical presentation and therapeutic history of a unique case diagnosed with Lassa fever and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in a 23-year-old man from Yomou prefecture in southeast Guinea identified with suspected Ebola Virus Disease (EVD) in the midst of an ongoing outbreak of that d...

Background: Malaria control interventions have been scaled up, particularly those in pregnant women in Guinea. Despite that, coverage of key malaria preventive measure (MPM) indicators remains low. Therefore, it is vital to understand the reasons behind that, especially for the low coverage of sulfadoxine-pyrimethamine (SP) and long-lasting insect...

What Guinean population perceived COVID-19 at the beginning of the pandemic.

The purpose of this study was to perform correlation of 5 cases and literature review. The study involved both children and adults. The major cause of retropharyngeal abscess was fish bone foreign body. Dysphagia associated with pain, fever and torticollis were the most common symptoms. Retropharyngeal abscess mainly occurred in the oropharyngeal a...

During the ongoing pandemic, anosmia, whether or not associated with aguesia, has been a common symptom in patients with SARS-CoV-2 infection causing COVID-19. We here report two cases of anosemia without aguesia in adults with COVID-19. The onset was brutal and symptomsa persisted for a few weeks after healing. The patients presented to the ENT De...

Background: In 2015, the laboratory at the Ebola treatment center in Coyah, Guinea, confirmed Ebola virus disease (EVD) in 286 patients. Cycle threshold (Ct) in the Ebola virus RT-PCR and 13 blood chemistry parameters were measured on admission and during hospitalization. Favipiravir treatment was offered to EVD patients on compassionate use basis...

During the 2013-2016 west African Ebola outbreak that affected West Africa, accelerated clinical trials, testing unproven but promising and potentially lifesaving experimental interventions emerged as a key component of the global outbreak. In 2017, no Ebola medical countermeasures had proven antiviral efficacy in patients. However, in September 20...

Author summary During the large Ebola outbreak that affected West Africa in 2014 and 2015, studies were launched to evaluate potential treatments for the disease. A clinical trial to evaluate the effectiveness of the antiviral drug favipiravir was conducted in Guinea. This paper describes the main challenges of the implementation of the trial in th...

Trial protocol. (PDF)

CONSORT statement. (PDF)

Background: By January, 2016, all known transmission chains of the Ebola virus disease (EVD) outbreak in west Africa had been stopped. However, there is concern about persistence of Ebola virus in the reproductive tract of men who have survived EVD. We aimed to use biostatistical modelling to describe the dynamics of Ebola virus RNA load in semina...

We report two cases of Ebola Viral Disease (EVD) in pregnant women. Both women were in the second trimester and survived. The foetus was initially alive. After respectively 31-32 days post negativation maternal blood EVD-PCR, both patients delivered a stillborn foetus with persistent PCR positivity of the amniotic fluid.

[This corrects the article DOI: 10.1371/journal.pmed.1001967.].

Background: Ebola virus disease (EVD) is a highly lethal condition for which no specific treatment has proven efficacy. In September 2014, while the Ebola outbreak was at its peak, the World Health Organization released a short list of drugs suitable for EVD research. Favipiravir, an antiviral developed for the treatment of severe influenza, was o...

We describe two Ebola virus (EBOV) RT-PCR discordant mother–child pairs. In the first, blood from the breastfeeding mother, recovering from EBOV infection, tested negative twice but her urine tested positive. Her child became infected by EBOV and died. In the second, the breastfed child remained EBOV-negative, although the mother's blood tested pos...