Alper Doventas

Alper Doventas
Istanbul University Cerrahpasa Medical School · Internal Medicine-Division of Geriatrics

Professor

About

74
Publications
5,724
Reads
How we measure 'reads'
A 'read' is counted each time someone views a publication summary (such as the title, abstract, and list of authors), clicks on a figure, or views or downloads the full-text. Learn more
489
Citations
Citations since 2017
32 Research Items
323 Citations
2017201820192020202120222023020406080
2017201820192020202120222023020406080
2017201820192020202120222023020406080
2017201820192020202120222023020406080
Additional affiliations
October 2012 - present
İstanbul University-Cerrahpaşa
Position
  • Professor (Associate)
Description
  • Division of Geriatrics
March 2010 - January 2016
İstanbul University-Cerrahpaşa
Position
  • Associate Prof.MD.
Education
March 2010 - December 2015
Istanbul University
Field of study
  • Geriatrics

Publications

Publications (74)
Article
Full-text available
Objective We aimed to determine the effects of pandemic on the inpatients in the geriatric unit by comparing the demographic and clinical characteristics, reasons for hospitalization, morbidity and mortality of the patients before and during pandemic. Methods The population of this retrospective, cross-sectional study consisted of inpatients in th...
Article
Full-text available
Background: Depression is one of the most common mental disorders among older adults and depressive symptoms are strongly associated with adverse health outcomes. We aim to examine whether depressive symptoms are associated with sarcopenia and malnutrition in older adults. Methods: We reviewed hospital records of 447 patients (≥65 years) who wer...
Article
Full-text available
Purpose: We aimed to evaluate frequency and risk factors of re-hospitalization which are not stated in comorbidity indexes in geriatric wards. Methods: A total of 585 patients who were admitted to tertiary care geriatric inpatient clinics at least once between 1 September 2017 and 1 September 2018 and who survived to discharge during initial hos...
Article
Full-text available
Aims In this study, we aimed to reveal mortality rates and factors affecting survival in geriatric patients infected with COVID-19. Methods This is a retrospective study of 873 geriatric patients with COVID-19 who were hospitalized between March 11, 2020 and March 11, 2021. Demographic, clinical, laboratory data, and treatment options were obtaine...
Article
Full-text available
Our aim is to evaluate and compare the most discussed articles on osteoporosis in academia and social media. The treatment of osteoporosis was the most popular topic in the top 100 citation (n = 31) and altmetric lists (n = 47). The general public, as well as academia, is curious about the treatment of osteoporosis.PurposeThe main aim of this study...
Article
Background Older patients use multiple drugs due to their comorbidities and most of these drugs have anticholinergic drug burden (ADB). We aimed to investigate the association between ADB and sarcopenia, anthropometric measurements, and comprehensive geriatric assessment (CGA) parameters in older adults. Methods Patients ≥65 years who applied to g...
Article
IntroductionIn 2019, The EWGSOP2 group made updates on the definition and diagnosis of sarcopenia. The aim of this study is to determine the possible risk factors for chemotherapy dose-limiting toxicity (DLT).Methods Newly diagnosed gastrointestinal (GI) cancer patients were included in this prospective observational study. Chemotherapy DLTs were r...
Article
Full-text available
Aim Serum fibroblast growth factor (FGF)-19 and FGF-21 levels have been reported to be associated with muscle hemostasis. This study aims to explore the relationship between the levels of these markers and sarcopenia. Methods In our single-center, cross-sectional study, patients over 65 years old presenting to the geriatric outpatient clinic were...
Article
Full-text available
PurposeThe purpose of this study is to evaluate the relationship between serum MMP9 (Matrix metalloproteinase), TIMP1 (Tissue inhibitor of metalloproteinase) levels and MMP9/TIMP1 ratio and primary sarcopenia in geriatric patients, and compare the diagnostic accuracy of such biomarkers with that of the SARC-F score. MethodsA total of 88 patients ag...
Article
Aim To investigate the relationship between handgrip strength with types of urinary incontinence (UI) and pelvic floor muscle strength (PFMS) in women. Methods Ninety‐two women, who presented to the geriatric and urology outpatient clinics complaining of UI between July 2019 and February 2020 and had indicated to undergo urodynamic assessment afte...
Article
Full-text available
*Objective: The aim of our study is to analyze the patients followed with the diagnosis of pneumonia in our geriatric clinic and discuss the effect of vaccination on prognosis by questioning the status of the vaccination before infection. *Materials and Methods: Patients who were diagnosed with pneumonia in the geriatric clinic between January 2017...
Article
Full-text available
Objectives: We aimed to investigate the factors affecting mortality of patients aged ?65 years who were hospitalized with the diagnosis of new coronavirus pneumonia (COVID-19). Methods: This is a retrospective study of ?65 years paients with COVID-19 who were hospitalized in Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty between Marc...
Article
This study aimed to investigate the lifetime prevalence and risk factors for allergic rhinitis and asthma in geriatric outpatients in three big cities of our country. Elderly patients visiting geriatric outpatient clinics at university hospitals were included in this study. Two questionnaires were completed by trained investigators in face-to-face...
Article
Full-text available
Background: The aim is to validate Turkish version Rowland Universal Dementia Assessment Scale (RUDAS). Methods: One hundred forty patients (>65 years) were included. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition -V was used in all patients. Rowland Universal Dementia Assessment Scale was applied for 2 days. Results were c...
Article
Aim: To determine the relationship of leptin with vitamin D and parathormone (PTH) levels in postmenopausal women who have no osteoporosis and to evaluate the effect of these three parameters on bone mineral dansity and bone homeostasis. Methods: Sixty-eight postmenopausal patients with no osteoporosis, who attended the general internal medicine, g...
Article
Full-text available
Aim: In order to analyze the relationship of Hashimoto’s thyroiditis with vitamin D and osteoclastogenic markers, we investigated vitamin D, osteoprotegerin (OPG) and receptor activator of nuclear factor ligand (RANKL) levels in patients over 60 years with and without Hashimoto’s thyroiditis. Methods: Eighty three female patients (49 with and 34 w...
Article
Full-text available
Background Data on the prevalence of fecal incontinence in elderly patients admitted to outpatient clinics in Turkey are scarce. AimsThe aim of this study was to assess the prevalence of fecal incontinence and the associated risk factors in the elderly outpatients. Methods Patients 60 years and older admitted to a geriatrics outpatient clinic betwe...
Article
Full-text available
Background/aim: The aim of this study was to assess the risk of malnutrition in hospitalized patients with three different tests and to compare these tests in terms of long hospitalization periods and sarcopenia. Materials and methods: Hospitalized patients in an internal medicine clinic were enrolled in this cross-sectional study. Patients were gr...
Article
Background Alteration in energy expenditure or metabolism is the most accused risk issue for the onset and for the course of neurodegenerative cognitive disorders. Neuropeptides are suggested to be related with learning and memory. Phoenixin (PNX) is the most recently reported neuropeptide and we aimed to compare the plasma level in people with sub...
Article
Background In this study we aimed to explore the role of inflammation in subjects with mild Alzheimer dementia (AD), mild cognitive impairment (MCI) and subjective cognitive decline (SCD) via new potential inflammation markers of Neutrophil-lymphocyte ratio (NLR) and Platelet-lymphocyte ratio (PLR). NLR and PLR are useful and cost-effective biomark...
Article
Aim: Bioelectrical impedance analysis is a promising method in determining the body compartments in hemodialysis patients. In this study, we aimed to investigate the agreement between two widely used methods: the single-frequency and multi-frequency bioelectrical impedance analyses. Methods: Maintenance hemodialysis patients were enrolled in the...
Article
Full-text available
Introduction: This study aimed to evaluate the role of protein oxidation and DNA damage in the elderly hypertensive (HT) patients. Materials and methods: This study consisted of four groups: two elderly groups with 30 HT patients and 30 normotensive healthy volunteers, and two young groups with 30 HT patients and 30 normotensive healthy voluntee...
Article
Full-text available
Introduction: Hypertension is an important risk factor for dementia as much as the morbidity and mortality of cardiovascular disease. Sustained hypertension is also more related to that risk. The aim of the study was to determine the relationship between 24-h ambulatory blood pressure monitoring (ABPM) and cognitive functions in elderly hypertensi...
Article
The aim of this clinical study was to evaluate the influence of aging on the levels of lipid peroxidation (quantified as thiobarbituric acid-reactive substances (TBARS) content), lipid hydroperoxide (LOOH), hexanoyl lysine (HEL), 8-iso-prostaglandin F2α (8-iso-PGF2α) and total antioxidant capacity (TAC), and determine their relationships to the dem...
Article
Full-text available
Objective: Polypharmacy, quite common in elderly patients, is an important issue, resulting in increased morbidity and mortality. This study aimed to examine polypharmacy rates and drug usage characteristics in elderly patients. Second aim of this study was to compare our results with other published studies. Methods: In a retrospective design, we...
Article
Full-text available
Objective: The aim of this study was to investigate the presence of primary sarcopenia in older patients with normal nutrition and to assess the relationships between the primary sarcopenia with anthropometric measurements. Design and methods: In this prospective clinical cross-sectional study, six-hundred patients who applied to Polyclinic of G...
Article
Objective: Cognitive and functional geriatric assessment may change in acromegaly. Herein we aimed to determine at which points geriatric assessment of the cases with acromegaly differs from that of general elderly population. Design: In this comparative cross-sectional study, a total of 30 cases with acromegaly (controlled n = 14, uncontrolled n =...
Article
Purpose Obesity and bone metabolism are interrelated. The aim of this study is to investigate the relationship between obesity and bone markers, leptin and insulin resistance in post-menopausal osteoporosis. Material and methods Four study groups were included in the study. Group 1 (n = 19): osteoporosis (T-score < –2.5 at the lumbar spine and/or...
Article
Full-text available
Introduction: We aimed to determine changes in geriatric assessment of cases with acromegaly. Methods: 26 elderly cases with acromegaly (controlled/uncontrolled: 15/11, F/M: 17/9) were included. 20 age, gender and BMI matched cases without acromegaly composed control group (CG) (F/M: 10/10). Presence of concomitant diseases and educational level we...
Article
Background/objectives: Sarcopenia and sarcopenic obesity (SO) are geriatric syndromes leading to physical disability, poor quality of life and death. The aim of this study was to investigate the prevalence of sarcopenia and SO in nursing homes in Turkey and to define local disparities for diagnosing sarcopenia and SO. Subjects/methods: This cros...
Article
Background and aim Malnutrition is related with serious morbidity and mortality in institutionalized older adults. The aim of this study is to determine the frequency of malnutrition in nursing homes and care homes and to identify the factors associated with malnutrition in these settings. Methods This multicenter study was conducted in 14 centers...
Article
Full-text available
Autosomal dominant polycystic kidney disease (ODPKD) is characterized by presence of multiple cysts in kidneys and other organs, and it is the most common hereditary kidney disorder. Approximately 8-10% of all cases progress to end stage renal failure. There may be multiple cysts in different sizes, widespread in the cortex and medulla of both kidn...
Article
Full-text available
Background/aims: The aim of the study is to evaluate the correlation between c-erb-B2 and CD44 overexpression and survival of patients with gastric cancer. Methodology: The paraffin blocks of 48 patients with gastric carcinoma were retrospectively analyzed. The pathological specimens were stained with CD44 and c-erb-B2 by immunohistochemical met...
Article
Myxomas are the most common types of primary cardiac tumors. Primary cardiac myxomas are typically encountered in the left atrium. Although they are generally benign on histopathological examination, they may cause cerebovascular embolism and mitral valvular obstruction due to their critical location. Myxomas are rarely asymptomatic. Here we report...
Article
The RLS is an underdiagnosed condition, characterized by unpleasant sensations in the legs. Pathophysiological mechanisms may include iron deficiency as reflected by low serum ferritin levels and dopaminergic system dysfunction. The purpose of our study was to investigate the prevalence and characteristics of RLS in the elderly and the relation of...
Article
Objective: Although thyroid disease is frequent in the population, it is not clearly established who should be screened for TSH. The aim of this study was to investigate the comorbidities related to thyroid disease and the value of screening TSH. Material and Method: The study included 796 consecutive patients. Age, sex, diagnoses of the patients w...
Article
Aim of the study was to investigate the replicability and reliability of the multi-dimensional health assessment questionnaire (MDHAQ) and visual analog scale (VAS) in young and elderly individuals with chronic pain. Ambulatory patients, 20 of them aged above 65 years and complaining about chronic pain and 20 patients with the age of 40 and younger...
Article
The purpose of this study was to determine outcome of the ratio of metastatic lymph nodes to the total number of dissected lymph nodes (MLR) in patients with gastric cancer. We retrospectively analyzed 111 patients who underwent D2 lymph node dissection. The prognostic factors including UICC/AJCC TNM classification and MLR were evaluated by univari...
Article
Full-text available
Pneumatosis intestinalis (PI) is an uncommon disease defined as gas-filled cysts that are found in the wall of the gastrointestinal (GI) tract. The exact causes of PI are still unclear, but it may associated with coexisting diseases, such as some GI disorders, connective tissue disease, some medication and drugs, and rarely malignancy. The most com...
Article
Full-text available
Dicrocoelium dentriticum (D. dentriticum) is a liver fluke induced biliary obstruction. Infection usually occurs in herbivores such as sheep, goats and deer; human infection is very rarely encountered in clinical practice. We report on a 65-y-old female presenting with biliary obstruction caused by D. dentriticum. Following treatment with tricloben...
Article
Full-text available
Retroperitoneal fibrosis (RPF) is an uncommon disorder that may cause ureteric obstruction with renal damage. Pergolide, a dopaminergic agonist used in the treatment of Parkinson's disease, has rarely been related to the development of RPF. We report on a 78-year-old woman with Parkinson's disease who presented with hydroureteronephrosis and develo...
Article
Full-text available
Humoral hypercalcemia is known to be an important cause of hypercalcemia associated with malignancy. Humoral hypercalcemia due to benign conditions has been rarely reported. We report on a 45-year-old woman with humoral hypercalcemia secondary to uterine leiomyoma. Following the surgical removal of leiomyoma by hysterectomy, serum calcium, suppress...
Article
Full-text available
Diabetes mellituslu olgularda immuniteyi ar~tınnak amacıyla, 54 diabetik ve 20 sağlıklı kontrol grubunda IgM, 19G ve IgA düzeylerini tayin ettik. Ayrıca diabetik olgularda glikometabolik kontrol durumu ile humoral immuniıe arasındaki ilişkiyi saptamak için de HbAlc il e immung lobulinl er arasındaki korelasyonu araştırdık. çalışmamızda diabetes mel...
Article
CA-125, a commonly used tumor marker for epithelial ovarian cancer, is a glycoprotein found in normal tissues derived from coelomic epithelia. Increased serum levels of CA-125 have also been found in nongynecologic tumors and nonmalignant diseases involving the peritoneum. A few recent studies and sporadic case reports have reported increased CA-12...

Network

Cited By

Projects

Projects (2)
Project
Geriatrik hastalarda primer sarkopeninin serum interlökin (IL)-6, IL-10, fibroblast büyüme faktörü (FGF)-2, FGF-23, Wnt-1 ve Wnt-3a düzeyleriyle ilişkisi
Project
65 yaş üstü hastalarda, sarkopeni tanısı için kullanılan antropometrik ölçümler, Bioimpedans analizi (BİA), el kavrama, 6 metre yürüme ve Barthel günlük yaşam aktiviteleri testleri ile SARC-F testi arasındaki ilişkileri; SARC-F testinin, sarkopeni tarama ve tanısında kullanılabilirliğini değerlendirmek