Alper Ceylan

Alper Ceylan
Gazi University · Department of Otorhinolaryngology

MD

About

73
Publications
13,921
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795
Citations
Citations since 2016
15 Research Items
367 Citations
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060
20162017201820192020202120220102030405060
Introduction
Endoscopic sinus surgery Thyroid surgery Functional nasal surgery
Additional affiliations
June 1997 - present
Gazi University
Position
  • Professor (Full)

Publications

Publications (73)
Article
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Background/aim: This study aims evaluation of olfactory and gustatory function of COVID-19 patients and possible risk factors for olfactory and gustatory disfunction. Materials and methods: The study included adult patients who diagnosed with COVID-19 in XXXX University Hospital between April 2020 and June 2020. Volunteered patients participated...
Article
Background/aim: The study aims to evaluate the usage of gold weight implants and monitor complaints and comfort of patients. Methods: A hundred and ninety-one implantations performed between January 2009 and January 2019 were analyzed. Patient satisfaction was measured through telephone surveys. Results: Seventy-eight patients included in this...
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The data on perioperative anaphylaxis (PA) in children is limited and usually reported with neuromuscular blocking agents and antibiotics. However we present a first pediatric case who developed PA with paracetamol unlike the literature.
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The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was isolated as the causative agent following the first case reports of pneumonia with unknown etiology in China. The 2019 novel coronavirus disease (COVID-19) significantly affected the health care systems in the world. The disease was accepted as COVID-19 pandemic by WHO. Diagnosis...
Article
Objective: To draw attention to the changes in the surgical method and indications of the Caldwell-Luc (CL) operation in the endoscopic era. Method: The patients who underwent the CL operation in the last seven years were included in the study. All operations were performed by otolaryngologists. The CL operation was implemented as two different typ...
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Amaç: Brankial yarık anomalileri (BYA), en sık karşılaşılan konjenital boyun patolojileridir ve genellikle boynun lateralinde karşımıza çıkarlar. Genellikle benign karakterde lezyonlar olup, tedavide ilk seçenek cerrahi eksizyondur. Bu çalışmada, kliniğimizde BYA nedeniye opere olan hastalar analiz edilerek, bulgularımızın literatür eşliğinde değer...
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Beyin omurilik sıvısı (BOS) rinore, nazal mu-koza ile subaraknoid boşluk arasında kafa tabanı, dura ve araknoid tabakalarını içeren bir defekte bağlı olarak gelişen ve burundan berrak renkli akıntıyla ka-rakterize bir klinik durumdur. Travma, BOS rinore vakalarında en sık saptanan etiyolojik sebeptir ve has-taların yaklaşık %70-80'inde görüldüğü bi...
Article
Although costal cartilage autograft has versatile usage, harvesting the graft is an invasive procedure with potential risks for complications. Therefore, it is important to make every effort to minimize these risks. Moreover, sculpting costal cartilage to the desired shape is challenging and time-consuming because of the natural rigidity. This stud...
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Introduction: Sinonasal inverted papilloma is noted for its high rate of recurrence. Staging systems aid to reduce recurrence and avoid excessive surgeries by guiding the selection of the optimal surgical approach. Objective: To evaluate the effectiveness of different endoscopic approaches in inverted papilloma by assessing tumor origin site and...
Article
Background Primary ciliary dyskinesia (PCD) patients have higher incidence of sleep disordered breathing which lead neurocognitive impairments such as attention‐deficit/hyperactivity disorder (ADHD). It may effect academic performance of children and may cause impairment in emotional relationships. This study aim to evaluate hyperactivity and atten...
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Background/aim: Isolated sphenoid sinus-derived lesions are rare and generally present with unclear symptoms. We are sharing our experience to be mindful of such lesions in differential diagnosis and to help accomplish successful treatment while avoiding revisions and complications.Materials and methods: Data from patients who underwent isolated sp...
Article
Introduction: Primary ciliary dyskinesia (PCD) can cause sleep disordered breathing (SBD). SBD may cause neurocognitive impairment in children. However, there is no study in the topic of PCD's effect on SDB and neurocognitive impairment in children. Methods: Thirteen PCD patients aged 8-18 years and 31 age-matched healthy controls were compared. EN...
Article
Samster's syndrome is defined with the tetrad of chronic rhinosinusitis and/or nasal poliposis, asthma and hypersensitivity to non-steroidal antiinflammatory drugs (NSAIDs). This is a well-known syndrome in the adult asthmatic patients and seen with a high percentage as 21% with oral provocation test (OPT). Rare case reports are present about the c...
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Background There has been no study investigating nonsteroidal anti-inflammatory drugs (NSAIDs)-exacerbated respiratory disease (NERD) exclusively in childhood. Therefore, in the current study, the authors aimed to evaluate the diagnostic features, clinical characteristics, and follow-up of adolescents diagnosed with NERD.Methods The patients who we...
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Objective: We shared our experience of endoscopic repair of cerebrospinal fluid (CSF) rhinorrhea. Methods A retrospective study of 30 patients with CSF rhinorrhea managed endoscopically from 2004 - 2014 in ENT Department of Gazi University. The cause of CSF rhinorrhea, localization and size of the defect, repairstyle, recurrence have been investiga...
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Choanal polyps (CPs) are unilateral benign masses usually originating from paranasal sinuses. Maxillary, ethmoid, and sphenoid sinuses are involved in order of decreasing frequency. In this study, the medical records of patients operated on with a clinical diagnosis of CP between 1998 and 2011 were reviewed. A total of 98 patients with a mean age 2...
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Salivary gland involvement is a rare presenting clinical feature of Wegener's granulomatosis (WG). Early recognition and identification of any unusual presentations of WG may enable the early commencement of appropriate treatment. We report a case in which the initial manifestation of the disease was parotid gland swelling, and discuss the manageme...
Article
Objective: To evaluate our thyroidectomy cases and present our experience. Methods: Sixty-eight thyroidectomy patients who were operated between 2008 and 2012 at Gazi University Faculty of Medicine, Ear Nose and Throat Department were included in the study. The demographic characteristics, pathological diagnosis, surgical procedures, complications,...
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Objective: The aim of this study was to describe a case of advanced juvenile nasopharyngeal angiofibroma from our practice and discuss the controversies of surgical treatment. Method: We present a 13-year-old boy who underwent external resection of advanced juvenile nasopharyngeal angiofibroma at the Gazi University medical faculty otorhinolaryngol...
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Several inflammatory and allergic disorders have been reported to correlate with interleukin-16 (IL-16). IL-16 is a highly potent chemotactic and chemoattractant molecule for eosinophils. Nasal polyposis (NP) has an inflammatory basis, and eosinophilia is a common finding in polyp tissue. In this study, we aimed to determine serum IL-16 levels in N...
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This is a prospective randomized study conducted in a group of children who underwent two methods of tonsillectomy: thermal welding or cold knife tonsillectomy. Parameters, such as postoperative pain scores, intraoperative blood loss, operation time, and postoperative bleeding rates, were analyzed to find out which technique is better. Ninety-one c...
Article
Castleman's disease is also known as angiofollicular lymph node or giant lymph node hyperplasia. It occurs most commonly in adults, equally in men and women. There are two clinical presentations as unicentric and multicentric forms. The two main histological types described are the hyaline vascular and the plasma cellular types. In this study, two...
Article
The objective of this study is to show the accumulation of bile acids in laryngeal tissues of laryngeal carcinoma patients. The present study compared the total bile acid level in the hypopharyngeal tissue, tumor tissue, and blood of 21 primary laryngeal carcinoma patients (study group) to that in the hypopharyngeal tissue and blood of 15 patients...
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Castleman's disease (CD) is a very rare disorder characterized by non-neoplastic growths in lymph nodes in any body regions, although over 60% of cases are located in the mediastinum. The head and neck is the second most commonly involved site, with up to 14% of cases. Of these, nearly 85% are located in the neck. These lesions rarely occur in the...
Article
Objective: We aimed to assess effect of intratympanic dexamethasone treatment on hearing in the patients who did not respond to conventional systemic treatment of idiopathic sensorineural hearing loss (ISHL). Materials and Methods: Fourteen consecutive patients with ISHL who did not respond to conventional parenteral treatment (methyl-prednisolone...
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The objective of our study was to assess the association of eNOS4 and eNOS296 polymorphisms of endothelial nitric oxide synthase (eNOS) gene with obstructive sleep apnea syndrome (OSAS). Forty-eight patients with OSAS and 181 healthy volunteers were included in the study. Genotype analyses were performed for eNOS intron 4 VNTR and exon 7, Glu298Asp...
Article
Objective; To discuss the incidence, clinical presentation, diagnosis and management of extracranial complications of chronic otitis media (COM). Materials & Methods; In this retrospective study conducted between 1963 and 2007, 97 extracranial complications of COM were included, Intracranial complications of COM and complications of acute otitis me...
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The aim of this study was to determine safety, pain perception, and the factors that may affect pain perception in patients undergoing certain otorhinolaryngologic procedures under local anesthesia with sedation. Prospective clinical study. Tertiary care academic medical centre. Two hundred thirteen patients operated on under local anesthesia with...
Article
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Aim: To describe the management of patients with elongated styloid process syndrome (Eagle's syndrome). Materials and methods: Sixty-one patients with elongated styloid process were treated between 2000 and 2005. Computed tomography examination defines those whose symptoms suggest the diagnosis. Patients with styloid processes longer than 25 mm...
Article
Radiofrequency reduction has become one of the most popular methods in the treatment of inferior nasal concha hypertrophy. During surgical treatment of inferior nasal concha hypertrophy, it is important to cause minimal injury to the overlying ciliated epithelium, since if the ciliated structure of this epithelium is permanently disrupted, it is ha...
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Schwannomas may rarely arise from the facial nerve and most commonly occur in the intratemporal part of the nerve. Extratemporal facial nerve schwannomas are extremely rare. Intraparotid schwannomas usually develop in adults and only one pediatric case has hitherto been reported. Herein, we reported the second case of facial nerve schwannoma in a 7...
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To determine the relationship between primary enuresis nocturna (PEN) and obstructive upper airway problems (OUAPs). Prospective, descriptive study. Tertiary care academic medical centre. Two groups of patients were included in the study. Newly diagnosed pediatric PEN patients between August 2004 and June 2005 were evaluated for OUAPs in the Depart...
Article
Unilateral vocal fold agenesis: an unusual cause of dysphonia. Unilateral vocal fold agenesis is a rare congenital laryngeal anomaly. To our knowledge, there have been no published reports about this clinical entity to date. A 6-year-old female patient was referred to our practice for persistent hoarseness of voice since birth. On physical examinat...
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Schwannomas are common tumors of the head and neck region, but they rarely develop in the suboccipital region. A 34-year-old woman presented with a left suboccipital mass causing local pain and neck stiffness. Following physical examination, fine needle aspiration biopsy was performed, which revealed benign cytology. In the light of preoperative ra...
Article
Pleomorphic adenoma (mixed tumor) is the most common benign neoplasm of the salivary glands. It is considered to occur primarily in the major salivary glands, such as the parotid and submandibular glands. It is much less common in the minor salivary glands, and rarely occurs at other sites, such as larynx, pharynx, trachea, lacrimal gland, and sino...
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Haemangiopericytoma is an aggressive vascular tumour with a high propensity for recurrence and metastasis. It typically occurs in the soft tissues of the extremities and trunk, and is rarely seen in the oral cavity. A case of haemangiopericytoma of the hard palate is presented. A 48-year-old woman presented with a gradually enlarging mass on the le...
Article
To assess regrowth potential of the tonsils following partial tonsillectomy performed by using radiofrequency. Follow-up results of 42 children (aged from 1 to 10 years) who consecutively had partial tonsillectomy with radiofrequency due to obstructive sleep apnea or snoring were evaluated for regrowth of the tonsils. Regrowth of the remaining tons...
Article
Objective: To compare effectiveness of four different treatment protocols in idiopathic sudden hearing loss (ISHL). Patients and Methods: The patients with ISHL were divided into four groups according to the treatment protocols applied; Group 1 (n=67) was treated with rheomacrodex, pentoxyphiline, heparin, papaverine, famotidine, and methylpredniso...
Article
To define the impact of patient-related and audiovestibular parameters on the prognosis of sudden hearing loss. Eighty-three patients were included in this retrospective study. All were treated medically. We recorded the patients' demographic parameters, systemic diseases, time elapsed between onset of sudden hearing loss and initiation of treatmen...
Article
Although some clues exist about the causative relationship of fungi and chronic rhinosinusitis, the relationship of nasal polyps and fungi has not been enlightened. The purpose of this study was to determine whether a relationship exists between fungi and massive nasal polyps and to evaluate current available diagnostic techniques for detection of...
Article
The purpose of this study was to evaluate the influence of sectioning of the Jacobson's (tympanic) nerve on middle ear functions. Twenty-five adult New Zealand rabbits were included in this study. The Jacobson's nerve was cut in the left ear of the rabbits (study group), whereas only a small mucosal incision was performed while keeping the Jacobson...
Article
Angiomatous polyps are the extremely rare variant of sinochoanal polyps that are characterised by dilated, large vascular spaces. A 27-year-old female patient presented with a three-month history of unilateral right-sided nasal obstruction and recurrent mild epistaxis. Paranasal computed tomography demonstrated a mass in the right maxillary sinus e...
Article
Treatment of nasal septal perforations which decrease quality of life is a surgical challenge with variable success rates. Numerous surgical methods have been proposed for closure of perforations. The technique described in this article, i.e. closure of the perforation with an upper lateral cartilage mucoperichondrial flap through an external septo...
Article
Foreign body aspiration (FBA) can occur in children and adults and be life-threatening. Symptoms may remain indolent for years and it may present a chronic picture. Foreign body aspiration in adults is associated with the presence of predisposing factors that become active when the protective airway reflexes disappear. In this case report we presen...
Article
We investigated the hemodynamic effects of local anesthetics with adrenaline used before septal surgery. In a prospective, controlled design, administration of local anesthetics was performed with and without adrenaline in 39 patients and 10 patients, respectively, undergoing septal surgery. Plasma adrenaline concentrations were measured before ane...
Article
OBJECTIVE:: The purpose of this study was to evaluate the influence of sectioning of the Jacobson's (tympanic) nerve on middle ear functions. METHOD:: Twenty-five adult New Zealand rabbits were included in this study. The Jacobson's nerve was cut in the left ear of the rabbits (study group), whereas only a small mucosal incision was performed while...
Article
Full-text available
Lymphangioma is a benign, hamartomatous tumor of the lymphatic system. It is usually found in the head and neck region and is widely regarded as a developmental lesion rather than a true neoplasia. Most lymphangiomas are present at birth (60%), and by the age of 2 years 80% to 90% are present. In the head and neck area, the most common location is...
Article
Inverted papilloma is a rare benign sinonasal tumor characterized by a potentially invasive nature. The lateral nasal wall represents the most common site of origin, whereas paranasal sinuses are frequently involved by extension. In contrast, primary sinus inverted papillomas have rarely been reported. The present study describes a 52-year-old man...
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Sphenochoanal polyp is a rare entity originating from the sphenoid sinus. It may be confused with an antrochoanal polyp on anterior rhinoscopy. Computerized tomography and nasal endoscopy have contributed to an increase of accuracy in the diagnosis of these masses. Simple polypectomy that leaves some part of the polyp inside the sphenoid sinus carr...
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We studied the incidence of Frey's syndrome and facial contour deformity in two groups of patients who had undergone superficial parotidectomy. One group was made up of 12 patients who were randomized to undergo reconstruction of the surgical defect with a sternocleidomastoid muscle flap; the other 12 patients did not receive a flap. All 24 patient...
Article
A case of arteriovenous fistula (AVF) arising in the auricle was presented together with its treatment. A 20-year-old man with an AVF on the right auricle was successfully treated with superselective embolization followed by ligation of the arteries supplying the fistula. The lesion underwent considerable regression within a follow-up period of fiv...
Article
Hamartomas are rare lesions in the larynx. Both clinical and histopathological findings may be misleading to both the physician and the pathologist in terms of diagnosis. A 51-year-old female with the complaints of nonproductive cough and severe dyspnea lasting for a year was found to have a subglottic, submucosal mass almost totally obstructing th...
Article
No surgery is free of complications varying from common minor problems to very unexpected and severe ones. In the case presented here, unilateral paralysis of the muscles of the tongue and ipsilateral vocal cord paralysis due to a lesion of the 10th and 12th cranial nerves occurred following a septorhinoplasty that was performed under endotracheal...
Article
To define the role of epiglottic anteversion in the etiology of globus pharyngeus (GP) and to evaluate the effectiveness of laser partial epiglottectomy in its treatment. Four patients who admitted to our clinic between 2001 and 2003 with the complaint of GP underwent laryngoscopic examination, which revealed a structurally anteverted epiglottis th...
Article
To assess the rate of thyroid gland invasion and the need for thyroidectomy in advanced laryngeal and hypopharyngeal carcinomas that require total laryngectomy. Between 1994 and 2001, 129 total laryngectomy with ipsilateral hemithyroidectomy and 14 total laryngopharyngectomy with total thyroidectomy operations were performed for primary squamous ce...
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We investigated the value of some tumor markers in the diagnosis and treatment follow-up of squamous cell carcinoma of the head and neck. Ferritin, lipid-associated sialic acid (LSA), carcinoembryonic antigen (CEA), squamous cell carcinoma (SCC) antigen and CYFRA 21-1 levels were determined in 28 patients with squamous cell carcinoma and in a contr...
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We compared the effects of pharyngeal neurectomy (PN) and cricopharyngeal myotomy (CPM) on postoperative deglutition in patients undergoing horizontal supraglottic laryngectomy (HSL). The study included 20 male patients (mean age 53 years; range 39 to 67 years) who underwent HSL for squamous cell carcinoma of the larynx. Tumor stages were T1 in two...
Article
Purpose: The Vertigo Handicap Questionnaire (VHQ) assesses common perceptions and the psychosocial consequences of vertigo, which include restriction of physical and social activities, and anxieties about vertigo and its effect on social relationships. The aim of this study was to determine the validity of the Turkish translation of the VHQ for Tur...
Article
Purpose of this study was to find out the effect of positional change and inhalant anesthesia on acoustic reflectometry (AR) parameters (reflectivity and curve angle). AR parameters were measured on 58 ears with otitis media in sitting position before anesthesia and in supine position under inhalant anesthesia, subsequently. Under anesthesia, ears...