Alireza Valizadeh

Alireza Valizadeh
Tehran University of Medical Sciences | TUMS · Department of Medical Nanotechnology

PhD of Medical Nanotechnology
Senior R&D Manager at Samanik Pharmaceutical Co. Senior Marketing Manager at Samanik Pharmaceutical Co.

About

29
Publications
14,716
Reads
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1,115
Citations
Citations since 2016
20 Research Items
924 Citations
2016201720182019202020212022050100150
2016201720182019202020212022050100150
2016201720182019202020212022050100150
2016201720182019202020212022050100150
Additional affiliations
December 2019 - present
Amirkabir University of Technology
Position
  • Research Assistant
Description
  • In this project, I designed, produced and optimized a primary bio-printer for department of Tissue Engineering.

Publications

Publications (29)
Article
Full-text available
Polycystic Ovarian Syndrome (PCOS) is a common female gynecological endocrinopathy disorder with ages ranging from 18 to 45 years. PCOS significantly increases the risk of infertility, cardiovascular diseases, and type II diabetes in women. Cinnamon has a strong history of decreasing insulin resistance and treatment of PCOS. Therefore, we aim to re...
Article
Full-text available
Background The cancer burden is rising rapidly worldwide, and it annually causes about 8.8 million deaths worldwide. Due to chemical drugs’ side effects and the emergence of resistance, the development of new green drugs has received much attention. We aimed to investigate whether solid-lipid nanoparticles containing essential oil of Zataria multif...
Article
This study investigated the cisplatin (anticancer drug) interaction with C20 bowl and C20H10(Bowl) molecule including hydrogen-saturated with using mPW1PW91 functional. The stability of the various isomers of drug interaction with C20 bowl was investigated. The interaction energy values were estimated in these systems. Changes in the structural par...
Article
Full-text available
The development of new green drugs is crucial because of the side effects and resistance to chemotropic drugs. Essential oils with a broad range of bioactivities such as antioxidant and anticancer activities are great resources for research and investigation. In this study, ingredients of the used Syzygium aromaticum essential oil (SAEO) were ident...
Article
Uncontrolled hemorrhage accounts for significant death risk both in trauma and surgery. Various bleeding control techniques have been emerged to augment hemostasis, which still has several limitations and drawbacks. In this study, epinephrine-entrapped chitosan nanoparticles were electrosprayed on a base pad and covered by a gelatin nanofiber layer...
Article
Full-text available
Wound healing is a complicated process that is affected by physiological and environmental conditions. An antibacterial agent and a physical supporter as wound dressing improve wound healing time and process. In this study, solid lipid nanoparticles (SLNs) containing Mentha longifolia, Mentha pulegium, and Zataria multiflora essential oils with a p...
Article
Major causatives for cutaneous leishmaniasis, the most common form of leishmaniasis, in the old world are Leishmania major and Leishmania tropica. Investigating the leishmanicidal effects of essential oils and preparing their nano/formulation is a promising approach for developing new green drugs. In this study, the ingredients of Cinnamomum zeylan...
Article
Full-text available
The aim of this study was to develop a novel oil-in-water (o/w) nanoemulsion gel containing levofloxacin for enhanced topical efficacy. Average particle size of sesame oil nanoemulsion without (SONE) and containing levofloxacin (SONEL) was found as 25.2 and 26.3 nm, respectively. Results from scratch test showed that SONEL had better proliferation...
Article
Full-text available
Background and objectives: Plant-derived essential oils (EOs) shave many usages in health and medicine, such as antibacterial agents. The aim of this study was the improvement of antibacterial activities of two EOs using nanotechnology. Materials and methods: Antibacterial activity was investigated on four important human pathogenic bacteria usi...
Article
Full-text available
Silver can inhibit bacterial activity. Previous studies showed that high concentration of silver nanoparticles (AgNPs) in compared to its lower concentrations is toxic for human health. However, by decreasing concentration of AgNPs, antibacterial activity also decreases. In this study, we investigated synergistic inhibitory activity of the combinat...
Article
Wound healing is a complex process and some agents have been reported to accelerate it. The aim of this study was to evaluate the healing effect of Eucerin-based ointments of lemon, sesame and olive oils on infected full-thickness wounds in rats. Wounds were created on the dorsal surface of Male Albino Wistar rats (n = 12). Wounds were treated with...
Article
The potential of stem cell therapy has been shown in preclinical trials for the treatment of damage and replacement of organs and degenerative diseases. After many years of research, its clinical application is limited. Currently there is not a single stem cell therapy product or procedure. Nanotechnology is an emerging field in medicine and has hu...
Article
Background and Aims: One of the important fields of dentistry is surgery for dental implants. In this field, dentistry has developed considerably in recent years amongst other fields of medicine from the perspective of digital device and software application. Surgical guides help dental surgeon for more precise, confident, easier and shorter surger...
Article
Full-text available
Objective (s): Among herbal oils, cinnamon bark oil has several advantages such as anti-inflammatory and antimicrobial activity. It is already reported that particle size of oil droplets affects their properties such as their antibacterial activity. In this study, we investigated inhibitory activity of cinnamon oil products including bulk, microemul...
Article
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Objective : Poly (lactic-co-glycolic) acid (PLGA) as a polymeric carrier for medicines has been extensively investigated because of its unique biodegradability and biocompatibility features. In this study, bovine serum Albumin (BSA), a protein which plays a key role in maintaining oncotic pressure was employed as a model protein to be encapsulated...
Article
Full-text available
Cancer is known as a dangerous disease at cellular and molecular level of organism which necessitates its detection and treatment in early stages. With the development of nanomedicine, the fabrication of structures/materials at the range of 1 to 100 nm offers good advantage to clinical applications. Among nanostructure, nanobubbles (NBs) have recei...
Article
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In this investigation, the structural, electronic properties, ¹³C and ¹H NMR parameters and the first hyperpolarizability of deferiprone are computed in the gas phase and various solvents at the M062X/6-311++G(d,p) level of theory. The solvent effect on the structural parameters, frontier orbital energies, ¹³C and ¹H NMR parameters is also explored...
Article
AIDS is one of the global pandemic diseases that results from infection by HIV and was estimated 34.2 million people infected in 2011 by this virus. The investigators had previously shown that by early antiretroviral treatment, the risk of AIDS/HIV-related illness and transmission reduced significantly. Nanomaterials could be applied to improving t...
Article
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The combination of nano/microfabrication-based technologies with cell biology has laid the foundation for facilitating the spatiotemporal analysis of single cells under well-defined physiologically relevant conditions. This combined technology allows so far unachievable insights into simultaneous characterization and manipulation of cells. Nano/mic...
Article
Full-text available
The investigators had previously shown that the risk of AIDS/HIV-related illness and transmission reduced (by 96%) with early antiretroviral treatment. Nanomaterials could be applied in early diagnosis of HIV by improving the ability to detect serum biomarkers of the blood-borne infectious diseases, with low sample volume, rapidity, and more sensit...
Article
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The human genome is exposed to mutations during the life cycle because of many types of changes in the DNA. Viruses, radiation, transposons, mutagenic chemicals, or any errors that happen during DNA replication or the meiotic process in the cell, may cause the mutation. Many mutations have no effect on phenotype or health, while some mutations caus...
Article
Lung carcinoma is the most widespread type of cancer worldwide, and is responsible for more deaths than other types of cancer. Lung cancer remains the chief cause of cancer-related deaths in both men and women worldwide, and is increasingly common in women. Each year, the number of deaths from lung cancer is greater than the number due to breast an...
Article
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Nanofibrous scaffolds have many advantages that make them excellent candidates for tissue engineering applications. The scaffolds with high surface area to volume ratio favor cell adhesion, proliferation, migration and differentiation. In the present study, the preparation of electrospun poly (ε-caprolactone)-polyethylene glycol-poly (ε-caprolacton...
Article
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Fibres with diameters less than 1000 nm (or 1 μm) are defined as nanofibres and they can be produced by several processing techniques, particularly by electrospinning (ES) technique. ES technique was invented by Formhals in 1934 that in this the electrical field imposes a uniaxial stretching of a viscoelastic jet derived from the polymer solution t...
Article
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Quantum dots (QDs) are one of the first nanotechnologies to be integrated with the biological sciences that used for imaging or tracking macromolecules/cells in cell/tissue. Because of QDs are important in biomedical and biological applications, identify a variety of synthesis methods to produce QDs with different characteristics also is particular...
Article
Efficient delivery of therapeutic and diagnostic molecules to the cells and tissues is a difficult challenge. The cellular membrane is very effective in its role as a selectively permeable barrier. While it is essential for cell survival and function, also presents a major barrier for intracellular delivery of cargo such as therapeutic and diagnost...
Article
Full-text available
This review introduces quantum dots (QDs) and explores their properties, synthesis, applications, delivery systems in biology, and their toxicity. QDs are one of the first nanotechnologies to be integrated with the biological sciences and are widely anticipated to eventually find application in a number of commercial consumer and clinical products....

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