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Publications (129)
Artículo originalmente publicado en:De Aluja AS, Sanz R, Espinosa F. El Mal de Playa. Intoxicación del ganado bovino con Lantana camara. VetMéx. 1970;1(4):7–12.- - - - - Se hace un estudio clínico y de laboratorio de los animales afectados por una entidad patológica conocida desde hace muchos años con el nombre de Mal de Playa, en una zona limitada...
Equids are still used for diverse chores in Mexico and are essential for the livelihoods of numerous families. Appropriate health and behavior are prerequisites for performing work without affecting welfare. This study aimed to assess the welfare of working equids in Tuliman, applying the hands-on donkey tool. This tool evaluates five dimensions (b...
Dentro de las prácticas de manejo previas a la matanza de animales de abasto, el transporte puede resultar a menudo en un estrés severo ocasionando lesiones e incluso la muerte, provocando considerables pérdidas económicas a la industria gana-dera (Carter y Gallo, 2008; Minka y Ayo, 2008). En este contexto, recientemente en algunos países se ha obs...
Taenia solium cysticercosis affects both humans and pigs. It has been considered an eradicable disease, and yet its prevalence remains stable in most endemic countries, due to the persistence of risk factors usually associated with the marginalization of an important sector of the population. In this chapter we will review key aspects of its epidem...
Objetivo. Evaluar el impacto de un programa de control de la teniasis-cisticercosis por Taenia solium con fines de erradicación, basado en educación de la comunidad y vacunación de cerdos. Material y métodos. Se estimó la prevalencia de cisticercosis porcina por medio de la palpación de lengua, ultrasonido y presencia de anticuerpos en suero, antes...
Objetive:
The impact of a control program is evaluated to eventually eradicate taeniasis-cysticercosis (Taenia solium) based on education and vaccination of pigs.
Materials and methods:
The prevalence of porcine cysticercosis was estimated using tongue inspection, ultrasound and determination of antibodies, before and three years after the appli...
This study assessed the effects of five different transport periods on physiometabolic responses and gas exchange in ostriches. It included 138 ostriches that were assigned to five experimental groups. G1 included 78 birds that were set aside as a reference group (RG). Each one of the four remaining experimental groups included 20 ostriches, which...
Abstract Herein, we present a review of our research dealing with vaccination against experimental, and naturally acquired, porcine Taenia solium cysticercosis, using T. crassiceps-derived antigens. Results strongly support that the different versions of S3Pvac vaccine are indeed effective against porcine T. solium cysticercosis. Immunological resu...
Abstract Our work of the last 25 yr was concerned with the development of a vaccine aimed to prevent porcine Taenia solium cysticercosis, based on cross-reacting Taenia crassiceps antigens that had proved protective against experimental intraperitoneal murine T. crassiceps cysticercosis (EIMTcC). In recent times, the efficacy of the vaccine has bee...
Prologo Segunda Edición por Dra. Carmen Gallo
Existe una creciente preocupación en el mundo por el bienestar de los animales en general y en particular de los de granja, que nos proporcionan alimentos. Los consumidores perciben un problema en el trato de los animales y requieren cada vez más antecedentes sobre lo que se entiende como calidad ética...
Prologo Segunda Edición por Dra. Carmen Gallo.
Existe una creciente preocupación en el mundo por el bienestar de los animales en general y en particular de los de granja, que nos proporcionan alimentos. Los consumidores perciben un problema en el trato de los animales y requieren cada vez más antecedentes sobre lo que se entiende como calidad étic...
La calidad de vida del animal aumenta al incrementarse o ampliarse la oportunidad de expresar sus comportamientos naturales, lo que implica más que satisfacer sus necesidades fisiológicas y conductuales, y va más allá de la definición negativa de bienestar, como la de Dawkins 5 , quien considera el bienestar animal como la ausencia de sufrimiento....
In an effort to develop an effective and affordable oral vaccine against porcine Taenia solium cysticercosis, the S3Pvac anti-cysticercosis vaccine was expressed in papaya calli. Taenia pisiformis experimental rabbit cysticercosis was used as a model to compare the efficacy of the oral vaccine vs. the injectable S3Pvac-synthetic and S3Pvac-phage ve...
GenBank staff is unable to verify sequence and/or annotation provided by the submitter.
Animal welfare is nowadays considered a science and it should be part of the curriculum of Veterinary Schools and Faculties. Present knowledge of anatomy, physiology, neurobiology and the nervous system in particular show that animals and men share many similar organic mechanisms. Observational and behavioural studies prove that animals are conscio...
Cysticercosis is a parasitic disease caused by Taenia solium which affects rurally bred pigs and humans in developing countries. The adult tapeworm parasite lives in the humans intestines, where it sheds thousands of eggs. Cysticercosis occurs after eggs are ingested by pigs or humans. In humans, cysticerci may cause neurocysticercosis, the most se...
Animal welfare is nowadays considered a science and it should be part of the curriculum of Veterinary Schools and Faculties. Present knowledge of anatomy, physiology, neurobiology and the nervous system in particular show that animals and men share many similar organic mechanisms. Observational and behavioural studies prove that animals are conscio...
This paper provides macroscopic and histological evidence on the statistically significant protective effects of S3Pvac-phage vaccination against porcine cysticercosis and hydatidosis. The study included 391 rustically bred pigs (187 vaccinated and 204 controls). Vaccination significantly reduced the prevalence of cysticercosis by 61.7%. Vaccinatio...
The S3Pvac synthetic vaccine, composed of three peptides (GK1, KETc1 and KETc12) effectively protects against cysticercosis under experimental and field conditions. Additionally, S3Pvac vaccine can effectively damage early-established cysticerci in experimentally lightly infected young pigs. This study was designed to explore if also fully-develope...
El Libro de Bienestar Animal y Calidad de la Carne es un texto en que mediante un grupo numeroso de especialistas han logrado enlazar la calidad de la carne con el bienestar animal. Es una gran contribución tanto para mejorar el bienestar animal como para incrementar la calidad de nuestros productos; demuestra que en Latinoamérica estamos preocupad...
Cysticercosis and hydatidosis seriously affect human health and are responsible for considerable economic loss in animal husbandry in non-developed and developed countries. S3Pvac and EG95 are the only field trial-tested vaccine candidates against cysticercosis and hydatidosis, respectively. S3Pvac is composed of three peptides (KETc1, GK1 and KETc...
E
sta obra cubre una necesidad que, desde hace mucho tiempo faltaba: la influencia que tiene el bienestar de los animales productores de alimento en la calidad de la carne que se consume, tanto la sanitaria, de primordial importancia para la salud pública, como la organoléptica.
En estos tiempos, en donde se ha masificado la producción animal, la r...
This study was designed to explore if each individual case of naturally acquired porcine cysticercosis, living in different geographic rural areas of central Mexico, is caused by one or more different specimens of Taenia solium tapeworm. The genetic variability among cysticerci from the same pig and that from different pigs was assessed by random a...
Current globalization policies demand animal welfare standards on animal transportation. In spite of international tendencies to commercialize meat cuts while decreasing live animal transit, transport is still one of the major problems in terms of animal welfare, besides carcass and meat byproducts' quality. The present review analyzes, in general...
Hormones play a significant role in murine Taenia crassiceps cysticercosis, and they may also participate in the susceptibility to Taenia solium cysticercosis. In the present study, in vitro effects are reported for human chorionic gonadotropin (hCG) on the larval stages of T. crassiceps (WFU strain) and T. solium. Our results reveal the presence o...
Current globalization policies demand animal welfare standards on animal transportation. In spite of international tendencies to commercialize meat cuts while decreasing live animal transit, transport is still one of the major problems in terms of animal welfare, besides carcass and meat by-products' quality. The present review analyzes, in general...
In many rural areas of Mexico, pork infected with Taenia solium is still being consumed, mainly because of the domiciliary slaughter of animals in villages where meat inspection does not exist. It follows that taeniasis cysticercosis continues to be an important health problem both for humans who suffer from taeniasis and neurocysticercosis and for...
Current globalization policies demand animal welfare standards on animal transportation. In spite of international tendencies to commercialize meat cuts while decreasing live animal transit, transport is still one of the major problems in terms of animal welfare, besides carcass and meat by-productsquality. The present review analyzes, in general t...
En muchas áreas rurales de México se consume la carne de cerdo infectada con el metacestodo de Taenia solium debido a la falta de inspección sanitaria de los animales que matan en forma clandestina o domiciliaria. Como consecuencia, la teniasis- cisticercosis constituye un problema importante de salud, tanto para la población humana que padece de t...
In search of reducing vaccine production costs', a recombinant M13 phage version of the anti-cysticercosis tripeptide vaccine (S3Pvac) was developed. The efficacy of S3Pvac-Phage vs. placebo was evaluated in a randomized trial that included 1,047 rural pigs in 16 villages of Central Mexico. Three to five months after vaccination 530 pigs were exami...
To describe and compare the clinical impacts of neurocysticercosis (NC) caused by Taenia solium in humans and pigs.
Comparative study of the brains of 16 asymptomatic pigs and 35 human NC cases (15 asymptomatic and 20 symptomatic).
In humans, cysticerci were more frequently located in the ventricles and subarachnoid space at the base of the brain (...
Cysticercosis is caused by Taenia solium, a parasitic disease that affects humans and rurally bred pigs in developing countries. The cysticercus may localize in the central nervous system of the human, causing neurocysticercosis, the most severe and frequent form of the disease. There appears to be an association between the prevalence of porcine c...
Taenia solium cysticercosis is still an important parasitosis in rural pigs in many developing countries, México among them. The main causes for the persistence of this condition are lack of hygiene in the rural communities, lack of education of the animal owners, lack of control in the trade of pigs and their meat and lack of conscientious meat in...
Taenia solium cysticercosis is a major parasitic disease that seriously and frequently affects human health and economy in undeveloped countries. Since pigs are an indispensable intermediate host, it is conceivable to curb transmission by reducing pig cysticercosis through their effective vaccination. This article reviews current knowledge on the d...
Hormones play a significant role in murine Taenia crassiceps cysticercosis, and they may also participate in the susceptibility to Taenia solium cysticercosis. In the present study, in vitro effects are reported for human chorionic gonadotropin (hCG) on the larval stages of T. crassiceps (WFU strain) and T. solium. hCG effectively promotes parasite...
In chronically infected BALBc/AnN male mice, Taenia crassiceps cysticercosis induces changes in the host's sex steroids hormone that lead to their estrogenization and deandrogenization, with possible repercussions on their susceptibility to infections. Here reported are the serum steroid levels in free range cysticercotic male boars. Therefore, the...
Review of experimental and observational evidence about various cestode infections of mammalian hosts revives hope for the development of an effective vaccine against adult intestinal tapeworms, the central protagonists in their transmission dynamics. As for Taenia solium, there are abundant immunological data regarding cysticercosis in humans and...
With the aim of genotyping Echinococcus granulosus cysts found in Mexican livestock, we collected hydatid cysts from the livers and lungs of pigs in slaughterhouses in the state of Morelos, Central Region of Mexico. DNA was extracted from the parasites and examined by polymerase chain reaction (PCR) of rDNA internal transcribed spacer 1 (ITS1-PCR),...
In order to identify the early stages of Taenia solium metacestodes, 12 pigs were each fed 100,000 viable eggs and later killed and necropsied at different times after infection. Hematoxylin-eosin (HE) and immunohistochemical techniques (IHCs) were used to identify onchospheres and cysticerci in different tissues. At 2 days postinfection (dpi) stru...
Vaccination of pigs may curtail Taenia solium transmission by reducing the number of cysticerci, the precursors of adult intestinal tapeworms in humans. Several antigen preparations induce protection against porcine cysticercosis in experimental settings but only one subunit vaccine (S3Pvac) has been tested and proved effective in the field against...
Taenia solium cysticercosis is a parasitic disease frequently affecting human health and the pig industry in many developing countries. A synthetic peptide vaccine (designated S3Pvac) against porcine cysticercosis has been developed previously as an aid to interrupt transmission and has been shown to be effective. The results of the present study s...
Teniasis-Cysticercosis continues to be a serious problem in many regions of Mexico and other developing countries. This zoono- sis has economic, sanitary and health implications. The rural porcine industry faces considerable economic losses. The sanitary implications refer to the lack of hygiene in many rural communities (there are no toilets, or t...
Teniasis-Cysticercosis continues to be a serious problem in many regions of Mexico and other developing countries. This zoono-sis has economic, sanitary and health implications. The rural porcine industry faces considerable economic losses. The sanitary implications refer to the lack of hygiene in many rural communities (there are no toilets, or th...
The disease caused by Taenia solium is progressively being recognized as a growing global threat for public human health and pig husbandry that requires the development of effective control measures. A central participant in the taeniasis/cysticercosis transmission network is the human carrier of the adult tapeworm because of its great potential in...
If a programme for the control of pig cysticercosis is to be effective it has to be based on good data on the local epidemiology of Taenia solium. In 2002-2003, in a cross-sectional study of pig cysticercosis in the Mexican state of Morelos, 1747 pigs that had been born and reared in rural areas of the state were checked for T. solium infection by...
Con el objetivo de controlar la teniasis (cisticercosis) se efectuó este estudio en el que se evaluaron los efectos que induce la radiación gamma en el metacestodo de Taenia solium (T. solium) en la evaginación in vitro y en el desarrollo de T. solium en el modelo del hámster. Los parásitos se obtuvieron de varios cerdos infectados y se irradiaron...
Body measurements (length from nape of neck to the withers; height to withers; length from withers to tail root; length from shoulder to tuber ischii; thoracic circumference; umbilical circumference) were taken and correlated with live weight from 160 donkeys (mean ± standard deviation = 6 ± 2.6 years old) in Central México. The age was assessed fr...
The aim of this work was to analyse the genetic origin of the Mexican Creole donkey, as well as its genetic diversity, by comparison with Spanish and African donkey populations by means of the D-loop region of mitochondrial DNA. To this end, the genomic DNA of 68 Mexican Creole donkeys from eight geographical regions in six States of the Republic o...
The S3Pvac synthetic vaccine composed of three peptides (GK1, KETc1 and KETc12) effectively protect against pig cysticercosis. Preliminary results point to an additional cysticidal capacity induced by S3Pvac or GK1 immunization. Herein, clear evidences of the cysticidal effect of S3Pvac but not of GK1 are presented. S3Pvac immunization of already e...
This collection of articles provides an account of five presentations delivered at the 19th International Conference of the World Association for the Advancement of Veterinary Parasitology (WAAVP) (held in New Orleans, Louisiana, USA, from 10 to 14 August 2003) in a symposium session on Donkey parasites, organised by Andrew Trawford and Catherine M...
There is no information on how free ranging pigs in the Mexican tropics distribute their time during the day and how these time budgets relate to their age and social behaviour of the pigs. It is known that in these areas pigs consume human faeces, which constitutes a serious public health problem as it maintains the life cycle of Taenia solium. Th...
The aim of this study was to test the capacity of recombinant phages to deliver antigens for vaccination against porcine cysticercosis. Thus, three peptides (KETc1, KETc12, GK1) and a recombinant antigen KETc7, previously proven to induce high levels of protection against pig cysticercosis, were expressed on the surface of the M13 bacteriophage at...
In two rural villages of the state of Puebla, Mexico, where Taenia solium pig cysticercosis is highly endemic, 120 pairs of young out-bred piglets were used to assay what proved to be an effective synthetic peptide vaccine against naturally acquired cysticercosis. Because the piglets used were all sired by one of three distinct studs in many differ...
Kinetics of the production of serum antibody levels and Th1 (IL-2, IFN-gamma) and Th2 (IL-4, IL-10) cytokines was studied in five pigs vaccinated with a synthetic tri-peptide vaccine (S3Pvac) against Taenia solium, a vaccine that has been shown protects pigs against naturally acquired infection. Healthy pigs of mixed genetic background, similar to...
Gamma irradiation of food is considered a possible approach to control food-borne diseases. In cysticercosis, previous studies have shown that irradiating (with 0.3 kGy) pork infected with Taenia solium larvae completely inhibits growth of the parasite. This study was conducted to evaluate the mechanisms that induce the effect of gamma irradiation...
Objetivo. Determinar la frecuencia de portadores de Taenia sp. y su relación con el diagnóstico de cisticercos en humanos en una comunidad rural del estado de Guerrero, México. Material y métodos. Para detectar portadores de Taenia sp. se analizaron 403 muestras de heces de personas, por medio de ELISA para coproantígenos de Taenia sp., así como 92...
To assess the frequency of Taenia solium carriers and its relationship with human cysticercosis in a Mexican locality.
A cross-sectional study was conducted in 1998, in a locality of Guerrero State, Mexico. Four hundred and three fecal samples were analyzed by enzyme-linked immunosorbent assay (ELISA) to detect Taenia sp coproantigen. Ninety two se...
Cuentepec is a rural village of central Mexico, where 1300 pigs were bred at the time of the study in conditions that favor Taenia solium transmission. The tongues of 1087 (84%) of these pigs were visually examined and 33% were found to be cysticercotic. Castration of male pigs increased prevalence from 23 to 50% (P < 0.001) and pregnancy in sows a...
Cysticercosis caused by Taenia solium frequently affects human health and rustic porciculture. Cysticerci may localize in the central nervous system of humans causing neurocysticercosis, a major health problem in undeveloped countries. Prevalence and intensity of this disease in pigs and humans are related to social factors (poor personal hygiene,...
This article concerns animal experimentation and official Mexican norm Nom 0062-Zoo-1999 entitled Technical specifications for the production, care and use of laboratory animals. The history of animal experimentation is briefly resumed. During the nineteenth century, doubts arose as to the right to expose animals to experimental procedures that fre...
Three of 4 pigs inoculated with 10 eggs of Taenia solium became infected. In those pigs infected with larger numbers of eggs, all became infected. Specific antibodies against the metacestodes were found in serum at day 30 postinoculation (PI) in animals that received 1,000 or more eggs and at day 60 in those that received 10 or 100 eggs. The concen...
Immunohistochemistry was used to examine the type of lymphocytes in muscle taeniosis-cysticercosis in naturally infected pigs. The inflammatory response studied was classified into lesions of grades 1, 3, and 5. In grade 1, with a minimal inflammatory infiltrate consisting of eosinophils and a few mononuclear cells, the immunostaining showed more C...
Taenia solium cysticercosis seriously affects human health when localised in the central nervous system (CNS) and causes great economic loss in pig husbandry in rural areas of endemic countries. Increasing the resistance to the parasite in the obligatory host pig may help in curbing transmission. Three synthetic peptides based on protein sequences...
Untreated Taenia solium cysticerci obtained from different naturally infected pigs vary notably in their capacity to develop into intestinal tapeworms in prednisolone-treated hamsters, whereas cells derived from Taenia crassiceps cysticerci after 2 mo of infection almost always develop to cysticerci in the peritoneal cavity of susceptible BALB/cAnN...
Untreated Taenia solium cysticerci obtained from different naturally infected pigs vary notably in their capacity to develop into intestinal tapeworms in prednisolone-treated hamsters, whereas cells derived from Taenia crassiceps cysticerci after 2 mo of infection almost always develop to cysticerci in the peritoneal cavity of susceptible BALB/cAnN...
This article reviews current knowledge on human and porcine cysticercosis caused by Taenia solium. It highlights the conditions favorable for its prevalence and transmission, as well as current trends in research on its natural history, epidemiology, immunopathology, diagnosis, treatment and prevention. Our opinions on the most urgent needs for fur...
Selected blood biochemical- and hematological values were determined in 32 donkeys before and after work at an altitude above 2 000 masl (meters above sea level). Animals of both sexes, aged 4 to 15 years, and weighing between 100 and 160 kg, were divided into Groups 1, 2, 3 carrying loads of 80 to 130 kg during 1, 2 and 3 h, respectively. Samples...
Se determinaron analitos bioquímicos y hematológicos selectos en 32 burros antes y después del trabajo a más de 2 000 msnm. Los animales, de sexo indistinto, tenían entre cuatro y 15 años de edad, pesaban entre 100 y 160 kg. Fueron divididos en tres grupos, que transportaron 80 a 130 kg durante una, dos y tres horas, respectivamente. Las muestras d...