Aline Reis de Carvalho

Aline Reis de Carvalho
Flemish Institute for Technological Research | VITO · Sustainable Chemistry

PhD

About

16
Publications
2,463
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149
Citations
Introduction
Currently researcher at VITO (Flemish Institute for Technological Research) working on analytical methodologies for organic chemical analysis (eg. PFAS) and microplastics, by chromatography (LC, GC) coupled to mass spectrometry (MS/MS, HRMS)
Additional affiliations
October 2021 - September 2022
University Bourgogne Franche-Comté
Position
  • PostDoc Position
Description
  • Development of analytical py-GC-MS for the analysis of natural organic matter and microplastics; evaluating pyrolysis critical aspects for the identification and quantification of microplastics in soil matrices
October 2018 - September 2021
Paul Sabatier University - Toulouse III
Position
  • PhD Student
Description
  • Method development for the analysis of microplastic particles (FTIR and pyr-GC-MS/MS); microplastic pollution monitoring in the biotic (fish and invertebrates) and abiotic (water and sediments) compartments in the Garonne river
August 2014 - August 2018
Federal University of Rio de Janeiro
Position
  • Analyst
Description
  • Pharmacist in the Brazilian Doping Control Laboratory working on method development and sample analysis for doping control purpose - mainly on liquid-chromatography coupled to mass spectrometry (tandem and high resolution). Focused on drug metabolism and detection issues of target molecules.

Publications

Publications (16)
Article
Zebrafish (Danio rerio) water tank (ZWT) approach was investigated as an alternative model for metabolism studies based on six different experiments with four model compounds. Sibutramine was applied for the multivariate optimization of ZWT conditions, also for the comparison of the metabolism among ZWT, humans, and mice, and for the role of CYP2B6...
Article
Plastic pollution is of major environmental concern. The impact of this pollution on the ecosystem is not fully understood mainly due to the lack of analytical methods to detect and quantify micro(nano)plastic. The use of mass spectrometry was initially not considered as technique of choice but a steady flow of recent publications show its promises...
Article
Microplastic pollution and ingestion are ubiquitous phenomena in freshwater ecosystems. However, our understanding of the role of trophic niche in microplastic ingestion is still limited. Here, we quantified the level of microplastic (700 μm to 5 mm) contamination for macroinvertebrates and fish within the Garonne river. We then used stable isotope...
Article
Microplastic (MP) pollution represents a novel environmental pressure acting on freshwater ecosystems. Improving our understanding of the dynamics of MP pollution in freshwater ecosystems is therefore a prerequisite for managing and limiting this pollution. In this study, we quantified the spatial and temporal variability of MP (size range 700 μm –...
Article
Freshwater ecosystems play an important role in transporting and accumulating microplastics. Spatial and temporal variability in microplastic pollution can create critical spots and moments of elevated pollution, however, the consequences of their interaction are still poorly understood. This study aimed to assess the interaction between urbanisati...
Article
Full-text available
The COVID‐19 pandemic has heavily impacted academics’ professional and personal lives, forcing many research groups (labs) to shift from an academic system primarily based on in‐person work to an almost full‐time remote workforce during lockdowns. Labs are generally characterized by a strong lab culture that underpins all research and social activi...
Preprint
Full-text available
Freshwater ecosystems play an important role in transporting and accumulating microplastics. Spatial and temporal variability in microplastic pollution can create critical spots and moment of elevated pollution, however their interactive effects are still poorly understood. The aim of this study was to assess the interaction between urbanisation an...
Thesis
The omnipresence of microplastic (MP) represents a novel environmental pressure acting on freshwater ecosystems and a better understanding of the dynamic of this pollution is needed. Here, we investigated the spatial and temporal changes in MP pollution (size range 700 μm – 5 mm) in the Garonne catchment (Southwestern France) and the consumption of...
Article
Full-text available
High environmental microplastic pollution, and its largely unquantified impacts on organisms, are driving studies to assess their potential entry pathways into freshwaters. Recreational angling, where many anglers release manufactured baits into freshwater ecosystems, is a widespread activity with important socio-economic implications in Europe. It...
Article
Full-text available
Robust and reproducible quantification of microplastic pollution in freshwater ecosystems requires the processing of a large amount of samples collected in varying environmental conditions. Such samples are characterized by a high amount of organic matter compared to microplastics and are highly variable in terms of the quantity and the composition...
Article
Testolactone is a potent steroid aromatase (CYP19A1) inhibitor, and its main effect is a reduction in estradiol and estrone and an increase in testosterone and androstenedione levels. In this work, we evaluated a zebrafish water tank (ZWT) as a model to investigate testolactone biotransformation and the possibility to increase knowledge regarding t...
Article
Full-text available
RESUMO As interações medicamentosas constituem um assunto de extrema relevância principalmente por sua alta incidência no ambiente hospitalar, no qual encontram-se pacientes mais debilitados e, frequentemente, submetidos a terapia com mais de dois medicamentos. Essa revisão aborda e discute a ocorrência das interações medicamentosas no âmbito hospi...
Article
The black market for pharmaceuticals has grown in recent years, largely due to the easy trade of products over the Internet. This trend poses a potential risk to consumers’ health, as it is not always possible to identify the origin of the products, which can be counterfeit. This study was designed to identify capsule components by full-scan mass s...
Article
Full-text available
Benign prostatic hyperplasia (BPH) is characterized by stromal cell proliferation and contraction of the periurethral smooth muscle, causing lower urinary tract symptoms. Current BPH treatment, based on monotherapy with α1A-adrenoceptor antagonists, is helpful for many patients but insufficient for others, and recent reports suggest that stimulatio...

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Projects

Projects (2)
Project
Characterization of natural organic matter and of microplastics in soil and water by Pyrolysis GC/MS
Project
Quantify the spatial and temporal variations in microplastics concentrations in water and sediments in the Garonne and its main tributaries. Study whether there is a transfer in the food web of microplastics. For that, develop an analytical method of identification and quantification of microplastics by pyrolysis-gas chromatography-mass spectrometry.