Alina Vinogradova

Institute of Antimicrobial Chemotherapy

The growth and spread of antimicrobial resistance (AMR) is one of the main threats to the healthcare system. Currently, along with the development of new antimicrobial drugs (AMPs) the basic approach to countering the spread of AMR is the rational use of existing medicines. Selection of the optimal drug taking into account its activity, doses, freq...

Objective. To analyse aggregated AST results for key microorganisms collected through the 2022 reports of chief specialists in clinical microbiology and antimicrobial resistance. Materials and Methods. The study included an analysis of the interpretation criteria used in the laboratories and an evaluation of the AST reports. Data were obtained...

Objective. To create local antibiotic resistance surveillance system using the AMRcloud online platform to provide evidence base for activity of antimicrobials (AM) and antimicrobial resistance (AMR) epidemiology. Materials and Methods. This study was conducted at the Pirogov National Medical and Surgical Center (Moscow, Russia). The study is prosp...

Objective. To analyze the features of local antibiotic resistance monitoring at hospitals in the Russian Federation. Materials and Methods. The study involved a survey of 305 institutions. The duration of data collection was 1 year (March 2020 – April 2021). The responses received were analyzed using the «R» programming language. Special packages w...

Objective. To assess the in vitro activity of ceftazidime-avibactam against clinical Enterobacterales and Pseudomonas aeruginosa isolates in various regions of Russia based on results of local susceptibility testing by disk diffusion method. Materials and Methods. Overall, 160 laboratories located in 61 Russian cities participated in this surve...

Objective. To review the basic principles and functionality of the AMRmap online resource. Materials and Methods. The AMRmap platform was developed using the R programming language and various downloadable modules – packages. The current annually updated version of EUCAST clinical breakpoints was applied for determination of categories of susce...

Surveillance of antimicrobial resistance (AMR) is crucial for identifying trends in resistance and developing strategies for prevention and treatment of infections. Globally, AMR surveillance systems differ in terms of organizational principles, comprehensiveness, accessibility, and usability of data presentation. Until recently, the data on AMR in...

В последние десятилетия проблема антибиотикорезистентности занимает одну из ключевых позиций в системах общественного здравоохранения во всем мире и требует особого внимания со стороны медицинского сообщества. Для отслеживания динамики чувствительности микроорганизмов, с целью своевременной коррекции антимикробной терапии, важную роль играют систем...

Continuing trends of antimicrobial resistance growth require a set of countermeasures, of which antimicrobial resistance surveillance at the global, national, and local levels plays one of the most important roles. Local surveillance systems are the most significant in controlling the changes in susceptibility of microorganisms in specific settings...

Objective. To evaluate antimicrobial resistance patterns of clinical Streptococcus pneumoniae isolates from different regions of Russia during 2014–2017. Materials and Methods. We included in the study 519 clinical S. pneumoniae isolates from 18 Russian cities. Susceptibility testing was performed by reference broth microdilution method (ISO 20...

Antimicrobial resistance is a growing threat to global public health and requires closer attention from the medical community. Antibiotic resistance monitoring systems play a key role in observing the antimicrobial susceptibility changes for rational prescribing antimicrobial therapy. Most current systems use data on a global scale; however, local...

The options for the use of «Plot By» tab in the web platform AMRmap are reviewed in the article. Description of some functionality is supported by the specific examples, and Klebsiella pneumoniae was selected as a study object. The analysis elements are supplemented with the explanations.

Interest in the issues of antibiotic resistance control and monitoring remains actual during the past decades. A significant number of findings confirm the ever-growing ratio of antimicrobial-resistant microorganisms. The article describes the information resources including data on antimicrobial resistance genes. Efficient monitoring and timely de...

Tuberculosis infection influences metabolic processes in the whole body. These deviations acquire special importance in childhood and adolescence, in the period of active growth and development. A literature review presents information about the status of osteotropic vitamins and minerals in children with tuberculosis infection. Their involvement i...

Legg–Calve–Perthes disease is a form of femur and hip joint pathology that belongs to the osteochondropathy group. The disease is caused by disorders of blood circulation and nutrition of articular cartilage leading to necrosis of the femoral head. The etiology of thedisease has not been clearly established yet. The destruction of the cartilage and...