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PhD student at AFMB, interested in virology, biochemistry, epitranscriptomics, enzymology, structural biology, currently focused on protein expression and purification, enzymatic assays, molecular and cellular biology, protein structure to better understand underlying mechanisms of HIV replication. As a teacher in life sciences, I am keen to learn about communication skills and tools.
As coronaviruses (CoVs) replicate in the host cell cytoplasm, they rely on their own capping machinery to ensure the efficient translation of their messenger RNAs (mRNAs), protect them from degradation by cellular 5′ exoribonucleases (ExoNs), and escape innate immune sensing. The CoV nonstructural protein 14 (nsp14) is a bifunctional replicase subu...
Respiratory syncytial virus (RSV) is a negative sense single-stranded RNA virus and one of the main causes of severe lower respiratory tract infections in infants and young children. RSV RNA replication/transcription and capping are ensured by the viral Large (L) protein. The L protein contains a polymerase domain associated with a polyribonucleoti...