Alice Décombe

Alice Décombe
Architecture et Fonction des Macromolécules Biologiques | AFMB · Department of Biochemistry

PhD student

About

2
Publications
177
Reads
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14
Citations
Introduction
PhD student at AFMB, interested in virology, biochemistry, epitranscriptomics, enzymology, structural biology, currently focused on protein expression and purification, enzymatic assays, molecular and cellular biology, protein structure to better understand underlying mechanisms of HIV replication. As a teacher in life sciences, I am keen to learn about communication skills and tools.
Additional affiliations
December 2018 - June 2019
French National Centre for Scientific Research
Position
  • Intern
July 2017 - August 2017
Institut de Génétique et de Biologie Moléculaire et Cellulaire
Position
  • Intern
February 2017 - June 2017
University College Cork
Position
  • Intern
Description
  • Protein production and characterization of phage proteins
Education
September 2019 - September 2022
September 2018 - July 2019
Sorbonne Université
Field of study
  • Fundamental Virology
September 2017 - September 2018
Université Paris-Sud 11
Field of study
  • Teaching science

Publications

Publications (2)
Article
Full-text available
As coronaviruses (CoVs) replicate in the host cell cytoplasm, they rely on their own capping machinery to ensure the efficient translation of their messenger RNAs (mRNAs), protect them from degradation by cellular 5′ exoribonucleases (ExoNs), and escape innate immune sensing. The CoV nonstructural protein 14 (nsp14) is a bifunctional replicase subu...
Article
Full-text available
Respiratory syncytial virus (RSV) is a negative sense single-stranded RNA virus and one of the main causes of severe lower respiratory tract infections in infants and young children. RSV RNA replication/transcription and capping are ensured by the viral Large (L) protein. The L protein contains a polymerase domain associated with a polyribonucleoti...

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