Alice Creedon

• King's College London

As plant-based diets gain traction, interest in their impacts on the gut microbiome is growing. However, little is known about diet-pattern-specific metagenomic profiles across populations. Here we considered 21,561 individuals spanning 5 independent, multinational, human cohorts to map how differences in diet pattern (omnivore, vegetarian and vega...

The role of diet in the prevention and management of menopausal symptoms is poorly understood 1,2 . Digital health platforms have the potential to optimise collection of population-level menopause symptom data particularly in a rapidly changing environment 2,3 . This study explored the prevalence of menopause symptoms utilising data collection capa...

There is a considerable body of evidence supporting the effects of increasing quantity of plantbased food consumption on health. Recently, there has been interest in the importance of diversity of plant-based food consumption, however, this remains less well understood ⁽¹⁾ . This study aims to (1) characterize the quantity and diversity of plant-ba...

Digital health technologies delivering dietary and lifestyle advice 1,2 may offer a contemporary approach to menopause symptom mitigation in a large population base ³ . This study aimed to evaluate alterations in both diet quality and menopause symptom burden following the implementation of an app-based, personalised dietary intervention in peri- a...

Plant-based foods encompass all food products derived from plant sources, such as fruits, vegetables, grains, legumes, herbs and spices, and nuts and seeds, plant-based fats and oils (e.g. olive oil) and plant-based beverages (e.g. tea and coffee). Consumption of diverse plant-based foods is a dietary pattern that has gained significant attention a...

Diets low in diverse fibre-rich plant foods are a major factor in the rise of chronic diseases globally. The BIOME study (NCT06231706) was a 6-week, parallel design randomised controlled trial in 399 healthy adults in the UK, investigating a simple dietary intervention containing 30+ whole-food ingredients high in plant polyphenolic compounds, fibr...

Background Over‐the‐counter supplements are commonly used to manage chronic constipation; however, their efficacy remains unclear. We aimed to investigate the effect of food, vitamin or mineral supplements on stool output, gut transit time, symptoms, and quality of life in adults with chronic constipation via a systematic review and meta‐analysis o...

Almonds are rich in unsaturated lipids, which play a role in some of the reported benefits of almond consumption for human health. Almond lipids are poorly bioaccessible due to almonds’ unique physicochemical properties that influence particle size distribution (PSD) following mastication, allowing much intracellular lipid to escape digestion in th...

Background: Almonds contain lipid, fiber and polyphenols and possess physicochemical properties that impact nutrient bioaccessibility, which are hypothesized to impact gut physiology and microbiota. Objectives: Investigate the impact of whole almonds and ground almonds (almond flour) on fecal bifidobacteria (primary outcome), gut microbiota comp...

Objectives The objective of this study was to investigate the impact of almonds, and almond form (whole, ground) on fecal Bifidobacteria (primary outcome) and gut microbiology, physiology, and symptoms in healthy adults. Methods Eighty-seven healthy adults with moderate fiber intake (<22g/d) were randomized to receive whole almonds (56 g/d), groun...

Nuts contain fibre, unsaturated fatty acids and polyphenols that may impact the composition of the gut microbiota and overall gut health. This study aimed to assess the impact of nuts on gut microbiota, gut function and gut symptoms via a systematic review and meta-analysis of randomised controlled trials (RCTs) in healthy adults. Eligible RCTs wer...

Nut consumption and the impact on gut microbiome and gut function in healthy people: a systematic review of randomised controlled trials - Volume 79 Issue OCE1 - A. Creedon, E. Hung, S. Berry, K. Whelan

Background: Evidence suggests that short sleep duration may be a newly identified modifiable risk factor for obesity, yet there is a paucity of studies to investigate this. Objective: We assessed the feasibility of a personalized sleep extension protocol in adults aged 18-64 y who are habitually short sleepers (5 to <7 h), with sleep primarily m...

The feasibility of lengthening sleep in habitually short sleepers and its effect on dietary intake, energy balance, and metabolic risk factors: A randomised controlled trial - Volume 76 Issue OCE4 - H.K. Al Khatib, W.L. Hall, A. Creedon, E. Ooi, T. Masri, S.V. Harding, L. McGowan, J. Darzi, G.K. Pot