Aliaë A R Mohamed-Hussein

Aliaë A R Mohamed-Hussein
Assiut University · Department of Chest Diseases

MD
Professor of Pulmonology, Chest Department , Assiut Faculty of Medicine, Assiut University, Egypt

About

162
Publications
69,492
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996
Citations
Introduction
Dr. Mohamed-Hussein is a Distinguished Professor in the School of Medicine, Assiut University, Egypt. Having received her MD degree from Assiut University in 2002, Dr. Mohamed-Hussein undertook her postgraduate training at Assiut University Hospitals and Medical University of Lubeck, Germany, Marburg and Gessen Medical University, Germany and has been an Attending Physician in the Pulmonology Department since 1991. She became a lecturer of Pulmonology, Assiut University in 2002. She was promoted to Professor in the School of Medicine, Assiut University in 2013. Her ongoing research interests are Pulmonary Medicine (particularly Allergy, immunology and asthma), Sleep Medicine, Bronchiectasis, Tuberculosis and bronchogenic carcinoma. She is member of Post Graduate scientific , Fund and Ethic
Additional affiliations
June 2021 - present
Assiut University
Position
  • Member of Assiut Faculty of Medicine Ethical committe
June 2020 - November 2020
Assiut University
Position
  • Supervisor of Isolation Unit for COVID-19
October 2019 - October 2022
Supreme Concil of Universities Egypt
Position
  • Member of Promotion Committee
Description
  • Promotion committee for Associate Professors and Professors of Pulmonology
Education
July 2017 - October 2017
Stanford University
Field of study
  • Writing in Science
January 2017 - September 2017
Harvard Medical School
Field of study
  • Improving Global Health: Focusing on Quality and Safety

Publications

Publications (162)
Article
Full-text available
Background Noninvasive ventilation (NIV) is a promising alternative to invasive mechanical ventilation (IMV) with a particular importance amidst the shortage of intensive care unit (ICU) beds during the COVID-19 pandemic. We aimed to evaluate the use of NIV in Europe and factors associated with outcomes of patients treated with NIV. Methods This i...
Article
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Background The COVID-19 pandemic presented major challenges for critical care facilities worldwide. Infections which develop alongside or subsequent to viral pneumonitis are a challenge under sporadic and pandemic conditions; however, data have suggested that patterns of these differ between COVID-19 and other viral pneumonitides. This secondary an...
Article
Full-text available
Background This pilot study included 68 cases with post-COVID-19 persistent cough (> 8 weeks), randomly allocated into two groups; intervention group (32 patients) received standard cough therapy, and montelukast 10 mg/day for 14 days and control group (36 patients) received only cough sedatives. Results We found a significant improvement in the n...
Article
Full-text available
Background: The coronavirus disease 19 (COVID-19) pandemic has spread rapidly around the globe with considerable morbidity and mortality. Coexistence of comorbidities with COVID-19 had consistently been reported as risk factors for unfavorable outcome. We aimed to evaluate the impact of comorbidities in COVID-19 patients on the outcome and determi...
Article
Full-text available
Purpose: To accommodate the unprecedented number of critically ill patients with pneumonia caused by coronavirus disease 2019 (COVID-19) expansion of the capacity of intensive care unit (ICU) to clinical areas not previously used for critical care was necessary. We describe the global burden of COVID-19 admissions and the clinical and organization...
Article
Full-text available
Background: The association between autonomic dysfunction and long-COVID syndrome is established. However, the prevalence and patterns of symptoms of dysautonomia in long-COVID syndrome in a large population are lacking. Objective: To evaluate the prevalence and patterns of symptoms of dysautonomia in patients with long-COVID syndrome. Methods:...
Article
Background Since being declared a global pandemic, Coronavirus disease 2019 (COVID-19) took over healthcare providers and researchers’ interest. However, other epidemic diseases, including tuberculosis (TB), are still a health issue that aggravate under the umbrella of health facilities exhaustion. This study aims to evaluate the impact of the COVI...
Article
Background Tuberculosis (TB) is considered one of the most common causes of bronchiectasis. Bronchiectasis increases clinical and financial burden of patients with TB. Here, we aim to assess the prevalence of bronchiectasis and its characteristics in patients with TB. Results Over 1 year duration, 85 patients with confirmed TB were enrolled in the...
Article
Full-text available
Background: The radiologic pulmonary inflammatory index (PII) may be used as an early predictor of inflammation as laboratory assessments in COVID-19 cases. The purpose of this study was tocompare the clinical and radiological features between cases of COVID-19 necessitating admittance to the intensive care unit (ICU) and those who did not, and to...
Article
Full-text available
Purpose: The number of patients ≥ 80 years admitted into critical care is increasing. Coronavirus disease 2019 (COVID-19) added another challenge for clinical decisions for both admission and limitation of life-sustaining treatments (LLST). We aimed to compare the characteristics and mortality of very old critically ill patients with or without CO...
Article
Introduction: Noninvasive positive-pressure ventilation (NPPV) is applied to facilitate weaning process and decrease complications associated with prolonged intubation. Interest has emerged in using Intelligent Volume Assured Pressure Support (iVAPS) to facilitate earlier removal of an endotracheal tube. Material and methods: This study was cond...
Article
Until now, there are more than two hundred million confrmed cases of COVID-19 including more than seven million deaths. Clinical trials of all three vaccines authorized for use in the UK (Pfzer–BioNTech, Oxford–AstraZeneca, and Moderna) have reported high vaccine efcacy. This rapid systematic review was initiated because no systematic review had be...
Article
Full-text available
Until now, there are more than two hundred million confirmed cases of COVID-19 including more than seven million deaths. Clinical trials of all three vaccines authorized for use in the UK (Pfizer-BioNTech, Oxford-AstraZeneca, and Moderna) have reported high vaccine efficacy. This rapid systematic review was initiated because no systematic review ha...
Article
Full-text available
Background: Good quality sleep is crucial for human well-being. COVID-19 pandemic affected tremendously the quality of life in human specially the health professionals dealing with the patients with COVID-19 in difficult and unusual circumstances. Objectives: This study aimed to assess the sleep quality among the Egyptian health professionals durin...
Article
Full-text available
Background: Healthcare workers (HCWs) are at a high risk for disease exposure. Given the limited availability of nucleic acid testing by PCR in low resource settings, serological assays can provide useful data on the proportion of HCWs who have recently or previously been infected. Therefore, in this study, we conducted an immunologic study to det...
Article
Full-text available
BACKGROUND: Long COVID-19 syndrome refers to the persistence of symptoms for more than 12 weeks after the start of acute symptoms. The pathophysiology of this syndrome is not yet clear. OBJECTIVE : To assess long COVID-19 symptoms in hospitalised and non-hospitalised patients. METHODS : A cross-sectional survey was used. The study included 262 pati...
Article
Full-text available
Rational: Recently, a new "Post-COVID-19 Functional Status (PCFS) scale" is recommended in the current COVID-19 pandemic. It is proposed that it could be used to display direct retrieval and the functional sequelae of COVID-19. Aim of the study: The aim of the study was to assess the PCFS and to evaluate if age, gender, smoking, hospitalization,...
Article
Full-text available
Peri-operative SARS-CoV-2 infection increases postoperative mortality. The aim of this study was to determine the optimal duration of planned delay before surgery in patients who have had SARS-CoV-2 infection. This international, multicentre, prospective cohort study included patients undergoing elective or emergency surgery during October 2020. Su...
Article
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Background Determining the clinical features and outcomes of patients diagnosed with coronavirus disease 2019 (COVID-19) is fundamental to improve the understanding and adequate management of the novel illness. This study aims to identify the determinants of survival and the outcome within 30 days in hospitalized patients with COVID-19 infection in...
Article
Full-text available
Background There have been insufficient data for African patients with COVID-19 who are critically ill. The African COVID-19 Critical Care Outcomes Study (ACCCOS) aimed to determine which resources, comorbidities, and critical care interventions are associated with mortality in this patient population. Methods The ACCCOS study was a multicentre, pr...
Article
Full-text available
Background Being highly infectious disease, COVID-19 exhausts most of efficient healthcare systems worldwide. Simple and rapid risk stratification methods are mandatory to recognize severe patients. This study aims to highlight the simple available laboratory biomarkers of good predictive value for COVID-19 severity. Results Three hundred fifty-on...
Article
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Background: Preoperative SARS-CoV-2 vaccination could support safer elective surgery. Vaccine numbers are limited so this study aimed to inform their prioritization by modelling.
Article
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Background: The COVID-19 pandemic has led highly developed healthcare systems to the brink of collapse due to the large numbers of patients being admitted into hospitals. One of the potential prognostic indicators in patients with COVID-19 is frailty. The degree of frailty could be used to assist both the triage into intensive care, and decisions...
Article
Objectives: To investigate implementation of evidence-based and supportive cares in ICUs, such as the ABCDEF, nutrition therapy, and ICU diary, for patients with coronavirus disease 2019 infection in ICUs and their association with ICU clinical practice and setting. Design: A worldwide, 2-day point prevalence study. Setting: The study was carried...
Article
Full-text available
1) Background: Colistin is a last-resort antibiotic used in treating multidrug-resistant Gram-negative infections. The growing emergence of colistin resistance in Escherichia coli (E. coli) represents a serious health threat, particularly to intensive care unit (ICU) patients. (2) Methods: In this work, we investigated the emergence of colistin res...
Article
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Introduction Increased mortality has been demonstrated in older adults with COVID-19, but the effect of frailty has been unclear. Methods This multi-centre cohort study involved patients aged 18 years and older hospitalised with COVID-19, using routinely collected data. We used Cox regression analysis to assess the impact of age, frailty, and deli...
Preprint
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Background Since the start of COVID-19 outbreak investigators are competing to develop and exam vaccines against COVID-19. It would be valuable to protect the population especially health care employees from COVID-19 infection. The success of COVID-19 vaccination programs will rely heavily on public willingness to accept the vaccine. Aims This stu...
Article
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Background: COVID-19 can be accompanied by acute neurological complications of both central and peripheral nervous systems (CNS and PNS). In this study, we estimate the frequency of such complications among hospital inpatients with COVID-19 in Assiut and Aswan university hospitals. Materials and methods: We screened all patients with suspected C...
Article
Full-text available
Background Interleukin-18 (IL-18) and interferon-γ (IFN-γ) are cytokines of crucial role in inflammation and immune reactions. There is a growing evidence supporting important roles for IL-18 and IFN γ in tuberculosis (TB) infection and anti-tuberculosis immunity. Objective To evaluate the role of polymorphisms in IL-18-607 and -137 and INF-γ +874...
Article
Full-text available
Background Being a newly emerging disease little is known about its long-lasting post COVID-19 consequences. Aim of this work is to assess the frequency, patterns and determinants of persistent post COVID-19 symptoms and to evaluate the value of a proposed Novel COVID-19 symptoms score. Patients with confirmed COVID-19 in the registry were included...
Preprint
Full-text available
Background and aims The coronavirus disease 19 (COVID-19) pandemic has spread rapidly around the globe with considerable morbidity and mortality. Coexistence of comorbidities with COVID-19 have consistently been reported as risk factors for unfavorable prognosis. We aim at this study to evaluate the impact of comorbidities in COVID-19 patients on t...
Article
Full-text available
Background Bronchiectasis may be associated and/or co-exist with respiratory diseases as bronchial asthma and chronic obstructive pulmonary disease (COPD) or non-respiratory diseases. However, data about this association and/or co-existence is little. The objectives of the study were to determine the prevalence of bronchiectasis among admitted pati...
Article
Full-text available
Introduction Cardiopulmonary exercise testing (CPET) is a methodology that has changed the approach to patients' functional evaluation, linking performance, and physiological parameters to the underlying metabolic substratum and providing exercise capacity descriptors, for example, peak oxygen uptake (peak VO 2). An accurate assessment of the exerc...
Preprint
Full-text available
Background Being a newly emerging disease little is known about its long-lasting post COVID-19 consequences. Aim of this work is to assess the frequency, patterns and determinants of persistent post COVID-19 symptoms and to evaluate the value of a proposed Novel COVID-19 symptoms score. Patients with confirmed COVID-19 in the registry were included...
Preprint
Full-text available
Arabic translation of post Covid-19 functional status score
Preprint
Full-text available
Background COVID-19 can be accompanied by acute neurological complications of both central and peripheral nervous systems (CNS and PNS). In this study we estimate the frequency of such complications among hospital in-patients with COVID-19 in Assiut and Aswan University Hospitals. Material and Methods We screened all patients with suspected COVID-...
Article
Full-text available
The disruption caused by the COVID-19 pandemic worldwide has resulted in numerous impacts on the environment and the climate. As a result of the Covid-19 pandemic; water bodies, the atmosphere and ecosystems are all affected, and have experienced significant positive and negative impacts. Human health during this pandemic is the primary concern to...
Article
Full-text available
Background The observations of some recent epidemiological studies offer hope for a reduced impact of COVID-19 for countries which practice universal BCG vaccination policy. Main body This report provides a correlation between the case fatality rates of COVID-19 and the percentage of BCG vaccination coverage in 183 most affected countries. The mai...
Preprint
Full-text available
Rational the radiologic pulmonary inflammatory index (PII) may be used as early predictor of inflammation as laboratory assessments in COVID-19 cases. The purpose of this study was to compare the clinical and radiological features between the cases of COVID-19 necessitating admittance to the intensive care unit (ICU) and those who did not, and to c...
Preprint
Full-text available
Rational: Recently, a new Post-COVID-19 Functional Status (PCFS) scale is recommended in the current COVID-19 pandemic. It is proposed that it could be used to display direct retrieval and the functional sequelae of COVID-19. Aim of the study: To assess the Post COVID-19 functional status in Egypt and to evaluate if age, gender, comorbidities have...
Preprint
Full-text available
Background: Determining the clinical features and outcomes of patients diagnosed with COVID-19 is fundamental to improve the understanding and adequate management of the novel illness. This study aims to identify the basic demography, underlying comorbidities and the mortality related factors of hospitalized patients with COVID-19 in Upper Egypt. P...
Article
Background: The observations of some recent epidemiological studies offer hope for a reduced impact of COVID19 for countries which practice universal BCG vaccination policy. Main body: This report provides a correlation between the case fatality rates of COVID -19 and the percentage of BCG vaccination coverage in 183 most affected countries. The ma...
Preprint
Full-text available
Introduction: COVID-19 outbreak was upgraded to pandemic on March 11. As of today, millions confirmed cases are officially reported in more than 200 countries or territories with many deaths (1). Owing to the health emergency, knowledge about COVID-19 is growing rapidly. Diabetes is among the most frequently reported comorbidities in patients infe...
Preprint
Full-text available
Background Social media became an alternative platform for communicating during medical crisis as COVID-19 pandemic. Aim of the study 1- to describe the use of social media by Physicians during Covid-19 outbreak 2- to determine how physicians obtain their medical information about the emerging disease 3- to determine physicians practice and how do...
Method
Full-text available
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Method
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Article
Full-text available
Background Morbidity and mortality due to chronic obstructive pulmonary disease (COPD) represents a worldwide pandemic, with exacerbations necessitating mechanical ventilation representing important aspects of disease management. Attempts to search for better weaning indices (WIs) is a continuous process. This study seeks for best index predicting...
Conference Paper
Introduction: There is rapid increase in global production and consumption in cement industry. Egypt is one of the greatest cement producers all over the world Cement dust particles is the major occupational hazard in cement factory. The main route of entry of cement particles to body by inhalation and swallowing leading to different clinical affec...