Ali Akbar Malekirad

• University of Tabriz

Background: Despite the widespread use of medicinal plants in the food basket of many families, using healthy herbs with safe nutritional standards is one of the necessities. Methods: In this review, the required data and related keywords (such as "latest methods of measuring and analyzing toxic elements in medicinal plants and foods, etc.) were co...

Background: Despite the widespread use of medicinal plants in the food basket of many families, using healthy herbs with safe nutritional standards is one of the necessities. Methods: In this review, the required data and related keywords (such as “latest methods of measuring and analyzing toxic elements in medicinal plants and foods, etc.) were co...

: Heavy metals cause significant issues when people are exposed to many specific types of them. They can cause many disorders and affect the biochemical pathways in the body. Herbs are known as one of the richest sources of modern patented drugs, particularly in Iranian references. Many metals, particularly heavy metals, are toxic. Various studies...

Migraine is one of the most common neurological disorders associated with recurrent attacks of moderate to severe headache. Oxidative stress may play an important role in migraine pathogenesis. This study aimed to measure and compare the serum levels of Selenium, total antioxidant capacity (TAC), and malondialdehyde) MDA (in migraine patients and h...

Heavy metals have both beneficial and nonbeneficial roles in the human body. Copper contributes to iron absorption and, with iron, mediates the production of red blood cells. Copper is involved in keeping bones, blood vessels, nerves, and immune function healthy. On the other hand, an excess of copper in the human body may lead to hepatotoxicity an...

Fruits could contain elements in various concentrations with positive and negative impacts on human health. The concentrations of essential elements including Iron, Copper, Zinc, Manganese, and Chromium in five types of fruits (peach, apple, grape, nectarine, and golden plum), the soil and irrigation water from six industrial zones of Markazi provi...

Introduction: Shoulder pain is one of the common musculoskeletal complaints of the patients with spinal cord injury. Corticosteroid injection to the subacromial bursa is one of the confirmed therapies which can be guided by anatomic landmarks or ultrasound. This study is aimed to compare these two methods to find the one with the highest therapeuti...

Multiple sclerosis (MS) is the most common neurological disease that happens at a young age. MS is an inflammatory disease; associated with the demyelination of the central nervous system. Therefore, some inflammatory factors are effective in the mechanism and progression of the disease. Melatonin, as a multi-effect substance including anti-inflamm...

The current study was conducted to investigate the concentration of bio-available aluminum (Al) in totally 90 samples of five types of fruits (grape, apple, nectarine, plum, and peach), the water used for irrigation and soil around the planets from six different regions of Markazi province in Iran with the aid of An Inductively coupled plasma atomi...

This study investigates the alcoholic extract effect of Alhagi camelorum on blood glucose and lipid profiles in diabetic rats made by streptozotocin (STZ). Male rats were divided into four groups. The control group received a normal diet. The diabetic group was induced by STZ and two diabetic experimental groups received alcoholic extracts of A. ca...

The current investigation was aimed to evaluate the oxidative stress (OS), blood factors, and neurocognitive state among cement factory workers who are exposed to dust during their work. Totally 41 cement exposed workers and 41 subjects as a control group were selected, and their OS, biochemical parameters, and a neurocognitive questionnaire were a...

Objective: Nonalcoholic fatty liver disease (NAFLD) is rapidly going to be one of the most common metabolic diseases which can negatively affect the liver function and needs to be more explored within the context of new and efficient therapies. The aim of this study was to determine the benefit of ‎ Cynara cardunculus var scolymus and Cinnamomum ze...

The third most abundant metal in the earth crust is aluminium (Al). Contamination of vegetables with Al poses a threat to human health, therefore it is essential to measure the amount of this metal in edible parts of vegetables and evaluate the possible health risks to human body through the food chain. Eight types of vegetables that are commonly u...

Vegetable production sometimes takes place in close proximity to heavy industry. It is necessary to determine if vegetables grown under these conditions contain high levels of pollutants. The semi-metals arsenic (As) and boron (B) are toxic in high concentration. Levels of As and B were determined in irrigation water, soil, and the green leafy vege...

Industrial processes, mining, weathering and erosion release tin in to the environment which can be absorbed by vegetables. The research was undertaken to determine levels of tin in the perennial and annual vegetables: Allium ampeloprasum L, A. wakegi L, Artemisia dracunculus L, Coriandrum sativum L, Lepidium sativum L, Mentha arvensis L, Petroseli...

Objective: The purpose of this work was to compare DNA damage, acetylcholinesterase (AChE) activity, inflammatory markers and clinical symptoms in farmers exposed to organophosphorus pesticides to individuals that had no pesticide exposure. Materials and methods: We conducted a cross-sectional survey with a total of 134 people. The subject group...

This study project aimed to determine the concentrations of five heavy metals (Al, As, Cd, Hg and Pb) in different fish species in the coast of the Persian Gulf in Iran. Ninety samples divided to three types’ fish including Rastrelliger kanagurta, Tenualosa ilisha and Scomberomorus commerson. The investigation performed by ICP-OES technique. The es...

Aflatoxins are fungal toxins, which may be found in food and due to negative health effects, they are of major concerns for human health and food industries. Aflatoxin M1 contamination in dairy products in Arak, Iran, 2013 was evaluated using ELISA method. Sample groups were comprised of 111 samples, including pasteurized milk (n = 56), raw milk (n...

This study was to investigate the potential anti-diabetic effects of alcoholic extract of Salvia hydrangea in rats. Thirty five male Wistar rats were divided into five groups namely non-diabetic control, diabetic control, and three experimental diabetic that received either Salvia hydrangea extract for 21 days at the doses of 100 and 200 or glibenc...

A wide range of liver and kidney disorders are associated with diabetes and there is a mutual relationship between diabetes and these diseases. Herbal medicine with having abundant ingredients is one of these options. The goal of this study was to compare the effects of alcoholic extract of aerial parts of S alvia hydrangea with glibenclamide on fu...

Background and Objectives. Presence of excessive nitrite and nitrate in foodstuff can have toxic and carcinogenic effects on humans. This study is aimed at measuring nitrate and nitrite in different foodstuffs available in Arak city market, Iran, in 2013. Methods. Totally 323 samples including stew (102 samples), beverage (116 samples), fruit (55 s...

In the surrounding environment, lead (Pb) can be released by repairing some parts of automobile engine and radiators repair works. Lead is very well-known as a neurotoxicant as some links exist between blood lead level (BLL) and neurological outcomes. This cross sectional study was performed on 35 male workers who were 23 - 40 and worked in an auto...

Abstract The aim of this comparative cross-sectional study was to assess neurocognitive impairment, haematological findings, and clinical symptoms of lead exposure among 316 male battery plant workers aged between 20 and 61 years. Compared to 123 matched controls (matching in age and years of work), the exposed workers showed significantly higher m...

The aim of this study was to determine oxidative stress status as well as ferrous (Fe) and Copper (Cu) levels in blood, neurocognitive impairment, and clinical markers in iron-steel workers. A comparative cross-sectional analysis was performed in 50 iron-steel workers who have been in contact with Fe and Cu in comparison with a control group contai...

About 25 million agricultural workers in the developing world suffer from at least one episode of poisoning each year, mainly by anticholinesterase-like organophosphates (OPs). The objective of this cross-sectional study was to establish the OP toxicity in 187 occupationally exposed farmers in terms of neurocognitive impairment, mental health statu...

Unlabelled: Medicinal plants are presumed to be natural sources of antioxidants that protect organisms from oxidative stresses. The present investigation aims to study the anti-oxidative stress activity of the Stachys lavandulifolia (S. lavandulifolia) plant. This trial was conducted on 26 healthy human subjects. The study was done in a before aft...

Manganese is an essential metal in human that functions in many enzymes. In contrast excessive exposure to Mn results in neurotoxicity. Accumulation of manganese damages central nervous system and causes Parkinson disease like syndrome called manganism. Mn neurotoxicity has been suggested to involve an imbalance in catecholamine neurotransmitters....

Non-alcoholic fatty liver disease (NAFLD) is becoming one of the most common causes of chronic liver disease worldwide that does not have obvious effective drug. The aim of this study was to determine the capability oîMelissa officinalisL. (Lemonbalm), Cinnamomum zeylanicum and Urtica dioica mixture infusion (1.5, 0.5 and 0.25 g/lOOmL) on patients...

Medicinal plants are considered as natural sources of antioxidant compounds which may protect organisms against oxidative stresses. The present study was conducted to investigate the antioxidant potential of lemon verbena (Lippia citriodora). This clinical investigation was performed on a group of 43 healthy subjects. They were invited to use 3 mg...

The aim of this paper was to study the toxicity of organophosphate (OP) pesticides in exposed farmers for electroencephalography, cognitive state, psychological disorders, clinical symptom, oxidative stress, acetylcholinesterase, and DNA damage. A comparative cross-sectional analysis was carried out in 40 horticulture farmers who were exposed to OP...

The aim of this study was to determine the capability of Melissa officinalis L. (Lemon balm) infusion on improvement of oxidative stress status in radiology staff that were exposed to persistent low-dose radiation during work. The study was a before-after clinical trial performed on 55 radiology staff. They were asked to drink Lemon balm infusion w...

The aim of this study was to determine oxidative stress status as well as blood lead (Pb) and zinc (Zn) levels and clinical markers in workers of a Zn-Pb mine. A comparative cross-sectional analysis was performed in 67 mine workers who have been in contact with Zn and Pb in comparison to a control group containing 67 healthy subjects with the same...

The aim of this study was to determine the anti-oxidative stress capacity of Cinnamomum zeylanicum (CZ) when administered in a controlled manner to radiology unit staff which are exposed to persistent low-dose radiation. A group of 27 radiology unit staff were invited to drink CZ (0.5 g powder mixed with 300 mL boiled water) twice daily for 2 weeks...

Medicinal plants are recognized as sources of natural antioxidants that can protect from biological system oxidative stress. The present cross-sectional before/after clinical trial was carried out to investigate the antioxidant properties of the decoction of the flowers of Echium amoenum Fisch & C.A. Mey in humans. A group of 38 healthy subjects wa...

Background: Cinnamomum zeylanicum is an important spice and aromatic crop used in folk medicine. Cinnamon is usually regarded as the bark of the C. zeylanicum tree. Objective: The objective of this study was to determine the antioxidative stress capacity of cinnamon in humans when administered in a regular and controlled manner. Methods: A total of...

Medicinal plants are recognized as sources of natural antioxidants that can protect from biological system oxidative stress. The present cross-sectional before/after clinical trial was carried out to investigate the antioxidant properties of the decoction of the flowers of Echium amoenum Fisch & C.A. Mey in humans. A group of 38 healthy subjects wa...

Health professionals exposed to anesthetic gases are at higher risk of reproductive, neurological, hematological, immunological, hepatic and renal system diseases. We investigated if oxidative stress induced by chronic exposure to anesthetic gases has any association with this matter. Plasma lipid peroxidation, total antioxidant capacity and total...

Unlabelled: Excessive production of reactive oxygen species has been observed following acute and chronic exposure to radiation in animal models which can lead to several detrimental and irreversible outcomes in vital organs. Aim of this study was to determine the oxidative stress status in radiology unit workers which are exposed to persistent lo...