Ali Sahraian

Shiraz University of Medical Sciences | SUMS · Department of Psychiatry, Research Center for Psychiatry and Behavioral Sciences

Background With the increasing survival rate of pediatric patients with leukemia, improving their quality of life (QoL) is the new challenge. Psychiatric disorders are among the significant confounding factors of the aforementioned patients’ QoL. Ninety-seven pediatric patients with leukemia were evaluated based on the Beck Hopelessness and SI scal...

Background Suicide is a major public health concern worldwide. Iran is no exception, with suicide rates increasing in recent years. Understanding the characteristics and related factors of suicide attempts can help inform suicide prevention efforts in Iran. Methods A cross-sectional study was conducted on patients who attempted suicide and were ad...

Purpose: Multiple sclerosis is a progressive and common chronic disease that affects about 2.8 million of the world's population. It has a series of neurological and psychological symptoms, one of which is sexual dysfunction. This symptom is more common in multiple sclerosis than other neurological diseases and is 5 times more common than in the ge...

Background: Obsessive-compulsive disorder is identified by intrusive thoughts and related compulsive behaviors. Memory complaints are controversial among obsessive-compulsive disorder patients. Objectives: The present study compared verbal, visual, episodic, and semantic memory between obsessive-compulsive disorder patients and healthy controls. Me...

Introduction: The Internet plays an important role in Medical Students' lives and has a great role in their learning and research. Covid-19 significantly changed students' lifestyles, leading to internet overuse or even addiction. Following the coronavirus disease (COVID-19) outbreak, virtual and online activities have increased considerably. In th...

Background and Objective: Most people who commit suicide suffer from psychiatric disorders, especially depression and substance-related disorders. However, major psychiatric disorders are not the sole risk factor for suicide, and other reasons, such as physical illness, may also be considered as an important factor for suicide ideation. This study...

Purpose: Due to the Corona virus pandemic in 2019, all around the world people hadto spend a long time in quarantine. The effect of this life style on the sexual behaviors of couples is an important issue that needs further investigation. The present study mainly aimed to investigate the effects of the COVID-19 outbreak on the sexual behaviors of m...

Introduction: According to the prevalence of sexual enjoyment reduction in total or partial laryngectomy patients, the present study aimed to evaluate sexual disorders among men who had undergone total laryngectomy. Materials and methods: In this cross-sectional case-control study, purposive sampling was carried out to select all the samples tha...

The Core Beliefs Questionnaire (CBQ) has three versions (Trait, Contingent, Other) that assess different levels of beliefs about the self. The current study translated these CBQ versions into Persian and psychometrically evaluated these measures. A student sample (n = 289) and a sample of individuals with depression (n = 60) completed the CBQ and o...

Objectives: In this double-blind, randomized clinical trial, the effectiveness of buprenorphine (BUPRE) in the reduction of anxiety symptoms among the methamphetamine (MA) dependents was evaluated. Materials and methods: The 60 MA-dependent patients were randomly assigned to three groups (0.1 mg, 1 mg, and 8 mg of BUPRE), The Hamilton Anxiety Ra...

Background Body dysmorphic disorder (BDD) and other psychological problems are more common in cosmetic surgery applicants.Objective The aim of this study was to investigate the frequency of the symptoms of BDD and narcissistic personality disorder in rhinoplasty candidates.Materials and Methods This descriptive cross-sectional study was performed o...

Genetic factors play an important role in the pathogenesis of schizophrenia. Dysregulations in the dopaminergic system have long been known to play an influential role in the development of this disorder. Although a large number of studies have investigated the association between genetic polymorphisms in the genes involved in this system and the r...

Objective: To investigate the rates of stress, anxiety, and depression among people in south Iran. Methods: We surveyed a sample of people during September, 2020: a group of the general population without a history of any chronic medical problems, patients with epilepsy, patients with diabetes mellitus (DM), and patients with cardiac problems. The...

Objective. The aim of the current study was to investigate the opinions of neurologists and psychiatrists in Iran on the necessity of COVID‐19 vaccination in patients with epilepsy (PWE). These data can help policy makers understand the concerns of these healthcare professionals. Methods. This was a survey study. On September 1st, 2020 we sent a qu...

Background The aim of this study is to examine the effects of quetiapine as an adjuvant treatment for obsessive–compulsive (OC) symptoms in patients with bipolar disorder (BD) type I. Methods In this 8-week double-blind placebo-controlled randomized clinical trial, 47 patients with BD in euthymic phase that had OC symptoms were randomly allocated...

Background: Little is known about which personality traits determine the effectiveness of various types of cognitive-behavioral therapy (CBT) on animal phobia. The objective of the present study was to investigate a possible association between personality traits and the outcome of single- and multi-session CBT. Methods: The present randomized c...

Introduction: Burnout is the product of prolonged stress in the workplace and this syndrome is revealed when individual's abilities are not enough to cope with demands of the workplace. Therefore, this syndrome is very common among people with careers involving helping others like medical doctors. Therefore, in this research, we evaluated the relat...

Background Animal phobia is one of the most common forms of specific phobias. This anxiety disorder challenges the medical student working with animal models. Regarding this, the present study was conducted to investigate the effectiveness of one- and multi-session cognitive exposure-based treatments in students with rat phobia. Methods For the pu...

Background: Epilepsy is a neurological disease that is associated with recurrent seizures that can be caused by abnormal brain activity. Psychogenic Non-Epileptic Seizures (PNES)have psychological bases and their clinical behavior is similar to epileptic attacks. Both patients with seizure and PNES often suffer from psychiatric problems. The aim of...

Purpose: We investigated the prevalence of attention-deficit hyperactivity disorder (ADHD) in adult people with epilepsy (PWE). We hypothesized that ADHD is common among adult PWE and, some clinical factors may be associated with ADHD. Methods: In this cross-sectional study, 200 adult PWE referred to our neurology clinic at Shiraz, Iran were rec...

Background: The purpose of this study was to compare the effect of 300 mg of bupropion and 8 mg of buprenorphine per day on the treatment of methamphetamine withdrawal cravings over a 2-week treatment interval. Method: Sixty-five methamphetamine-dependent men who met the DSM-IV-TR (Diagnostic and Statistical Manual of Mental Disorders, 4th editi...

Abstract Background: Premenstrual Syndrome (PMS) is a prevalent disorder among women. Personality traits are involved in severity symptoms of PMS. The present study was conducted to investigate the relationship between big five personality factors and premenstrual syndrome severity in child-bearing age women. Methods: In this cross-sectional study...

Introduction: This study aimed to explore the use of e-learning in medical education in Shiraz, Iran.Materials and Methods: A convenience sample of 300 medical students of Shiraz University of Medical Sciences was interviewed using a structured questionnaire. The questionnaire contained a series of questions on the demographic characteristics, acce...

Background This randomized clinical trial was aimed to evaluate the effect of oral use of tamarind seed powder as an herbal product in patients affected by premature ejaculation (PE). Materials and Methods In this study, 75 patients randomized in tamarind group (25 patients received daily 130 mg tamarind seed powder), paroxetine group (25 patients...

Background and objective: Our Objective is to study the effects of aripiprazole as an adjuvant treatment for obsessive and compulsive (OC) symptoms in patients with bipolar disorder (BD) type I, manic phase. Patients and methods: In this 8-week, double-blind, placebo-controlled randomized clinical trial, 56 patients with BD who had OC symptoms w...

Objectives A correlation between hyperhomocysteinemia, and depression has been reported. Saffron (Crocus sativus) is recommended for treatment of depression; hence, in this study the effect of co-administration of saffron and fluoxetine on plasma homocysteine and depression was evaluated. Material and methods This was a 4-week randomized and doubl...

Background: In recent years, availability of class material including typed lectures, the professor's Power Point slides, sound recordings, and even videos made a group of students feel that it is unnecessary to attend the classes. These students usually read and memorize typed lectures within two or three days prior to the exams and usually pass t...

Purpose/background: The aim of this study is to examine the effects of memantine as an adjuvant treatment for obsessive compulsive (OC) symptoms in patients with bipolar disorder (BD) type I, manic phase. Methods/procedures: In this 16-week double-blind placebo-controlled randomized clinical trial, 58 patients in the manic phase of BD who had OC...

Background: The Internet has become a fundamental part of modern life, it has given rise to various problematic behaviors. Some of these behaviors, such as prolific use of social media, frequent email checking, excessive online gaming, online buying and gambling, and viewing pornography cause significant impairment in everyday functioning of some i...

Different factors such as family and personality are related to suicidal attempt which play as protective role and risk factors. The present study aimed to investigate the differences between personality traits and family functions of suicide attempters who used and didn’t use mental health services. In this cross sectional case (non-user)-control...

Background: Lennox-Gastaut syndrome (LGS) is an epileptic encephalopathy, characterized by drug-resistant multiple seizure types. The aim of this study was to determine if the adjunctive use of electroconvulsive therapy (ECT) in patients with LGS and drug-resistant epilepsy is efficacious in decreasing their seizure frequency and also to investigat...

Background: Violent behavior in the workplace, or workplace violence (WPV), is considered a serious threat to the mental and physical health of employees. WPV ranges from verbal abuse to physical assaults and even sexual harassment. Objectives: Every medical student may be repeatedly exposed to violence in hospitals due to direct contact with the p...

Background: Twenty percent of married couples at reproductive age suffer from infertility. This common problem might cause significant problems in couples’ mental health and quality of life. Objectives: Accordingly, the goal of the present study is to evaluate the frequency of marital maladjustment in these patients in Shiraz,Iran. Patients and Met...

Introduction Epidemiological studies revealed that 21 to 34 percent of women around the world have been victim of physical assault by their spouse and spouse abuse have been more prevalent in developing countries. Objectives The most common form of violence against women is spousal abuse which is a dangerous factor and leads to serious psychologic...

Background: Methamphetamine abuse is a growing problem in the world especially in Asian countries. Objective: To depict the dramatic result of ECT in the therapy of methamphetamine psychosis, dependency and craving. Results: ECT has a dramatic outcome in the management of methamphetamine-induced psychosis. Conclusion: ECT can be practically empl...

Background: Hypertension (HTN) is a common condition with increasing prevalence rate. Hypertensive patients have a high prevalence of mental disorders, including anger. Objectives: The present study aimed to investigate the score of anger in hypertensive patients in comparison to the individuals with normal blood pressure in Shiraz. Patients and M...

Heroin abuse is a universal problem. The main objective is to demonstrate the benefits of low doses of clonidine, baclofen and ibuprofen (NSAID) in the management of heroin abuse. The method was to appraise blindly a single patient. In results usage of clonidine 0.3 mg, baclofen 75 mg and ibuprofen 1200 mg per day is very beneficial in the treatmen...

Objective: Violence imposed on wives by their inpatient psychiatric husbands has not been studied yet. The current study surveyed the rates and predictors of violence committed by inpatient psychiatric husbands towards their wives. Methods: A convenient sample of wives of 209 married male psychiatric inpatients completed a self-reported question...

Background: The history of coping with depression is important to consider, as it evolved from pure behavioral approaches that predate Behavioral Activation (BA) [the focus of this paper]. However current BA adds an idiographic, functional approach that explores both the client’s needs and goals and the environmental contingencies that support depr...

Abstract: At present, methamphetamine abuse is a considerable problem. To present usefulness of ECT in the management of methamphetamine induced psychosis.ECT can be a good choice in the treatment of this serious condition. Keywords: ECT, methamphetamine.

There are some animal studies suggesting the possible role of vitamin C for treating depression. However, the efficacy of vitamin C for treating adult patients with major depressive disorder (MDD) has never been examined. This 8-week randomized double-blind placebo-controlled clinical trial included adult patients with major depressive disorder acc...

Several studies have investigated the association between students' seating positions and their classroom performance. However, the role of personality traits on seating preference in the classroom has not been well investigated. The aim of the study was to understand how students choose their seats according to their personality traits in a classr...

Background: Diagnosis of psychogenic non-epileptic seizures (PNES) particularly in patients with epilepsy poses a challenge to physicians to care. This study is aimed at determining the frequency of depression and anxiety among Iranian patients with PNES. Materials and Methods: Sixty patients with PNES and one hundred age-and-sex matching healthy c...

Background It has not been examined trialed whether obsessive compulsive symptoms in patients with bipolar disorder respond to topiramate as an adjuvant treatment. Methods This 4-month double-blind placebo-controlled randomized clinical trial examined the efficacy and safety of augmentation with topiramat for treating the patients with bipolar dis...

Background: Obsessive-compulsive disorder (OCD) is not only one of the most prevalent psychiatric disorders, is also one of the most disabling medical disorders with some cognitive deficits, like poor cognitive inhibition.

Background: Locus of control (LOC) is one of the most important factors with a significant role in stress management and increase or decrease negative emotions, notably in the work environment with many occupational consequences. This effect is more prominent in those working in more stressful environments such as medical professionals including nu...

Background Managing and coping with occupational stress as a recognized problem in the modern era, is vital and important. Nursing is by nature a stressful occupation. Continuous and long-term stress can result in physical, psychological, and behavioral problems in nurses. We aimed to assess occupational stress in nurses working in surgical, intern...

Background: religious attitudes and behaviors have significant effects on life meaning. Behaviors such as praying may relax the person via hope. Secure relation to GOD and having goals and meanings in life may be a supportive way in problematic life events, so religious people can handle life stress more effective than others. The aim of current st...

The association between religiosity and happiness has been the focus of much recent research. The majority of them report a positive correlation between a religious attitude and behavior and the level of happiness. However, different findings have been reported. The aim of the current study was to test link between religiosity and happiness among a...

Background: There are many controversies with regard to the nosology and conditions causing psychosis in old age people. This study defines a symptom profile and differential diagnosis of late-onset psychosis. Method: 201 elderly persons with psychotic symptoms were recruited. All patients were interviewed based on SCID-1 to confirm the possible di...

Background: Many patients with schizophrenia suffer from metabolic symptoms and weight gain in which predispose them to obesity, diabetes, and cardiovascular problems. This trial examines the efficacy and safety of zonisamide on weight and body mass index in patients with schizophrenia being administered with atypical antipsychotics. Method: In...

Introduction: Medical students are less happy compared to other students in University because of specific education and work conditions. As happy and healthy personality people are responsible ones, we evaluated the happiness of Medical students and its relationship with age, gender, marital status and life style. Methods and Material: This study...

Few studies have examined suicidal ideation and behavior in hospitalized physically ill elderly patients, a group potentially at high risk. Our aim was to investigate the prevalence and risk factors for suicide ideation, and direct and indirect self-destructive behaviors among a sample of elderly inpatients. A cross-sectional study was conducted in...

Deficits in olfactory function are common features in neurodegenerative and neuropsychiatric disorders. Olfactory processing is related to dopamine metabolism and orbitofrontal cortex functioning, both known to be involved in the neurobiology of ADHD. Some investigations suggested alterations in olfactory processing (identification and detection th...

The seat selection and classroom dynamics may have mutual influence on the student performance and participation in both assigned and random seating arrangement. The aim of the study was to understand the influence of seat selection on educational achievement. The seating positions of the medical students were recorded on an architectural plan duri...

Background: Medical residents are a population who are at great risk to develop sleep disruption due to demanding clinical and academic duties..Knowing how much change in sleep wake pattern is associated with subsequent psychological distress could be useful to establish a systematic mental health program for medical residents. Method: a cross sect...

Introduction Sleep-wake cycle is one of human biological rhythm highly correlated to well being and general health status.Poor sleep quality, sleep disruption and changes in regular Sleep-wake pattern may cause physical and psychological burden such as impairment in job performance, decreased work efficiency and learning disability. Objective Heal...

Depression is a common psychological symptom in patients undergoing chronic hemodialysis. In the general population, low serum zinc level is associated with major depression. The current study surveys the possible relationship between the prevalence of depression and plasma level of zinc in patients on hemodialysis (HD). A total of 135 patients wit...

Glutaminergic dysfunction has been shown to be related to the pathphysiology of obsessive-compulsive disorder (OCD). Topiramate is an antiepileptic that inhibits glutaminergic action. The aim of this study is to evaluate the efficacy of topiramate augmentation in patients with treatment resistant OCD. This augmentation trial was designed as a 12-we...

Introduction: Substance abuse is a serious problem .Incidence of substance abuse in Iranian students is high. The current study surveys of substance abuse in medical students in southern Iran. Patients and Methods: From April 2008 to June 2009 in Iran, prevalence of substance use among 1000 Shiraz University medical students were assessed by a ques...

Autism is a complex neurodevelopmental disorder that forms part of a spectrum of related disorders referred to as Autism Spectrum Disorders. The present study assessed the effects of topiramate plus risperidone in the treatment of autistic disorder. Forty children between the ages of 4 and 12 years with a DSM IV clinical diagnosis of autism who wer...

Background: Medical students are a population who are at great risk to develop sleep disrup- tion due to demanding clinical and academic duties. Knowing how much change in sleep - wake pattern is associated with subsequent psychological distress could be useful to establish a systematic mental health program in medical schools. Methods: We performe...

Objective: In geriatric practice, the impact of psychological distress on health status has been undermined due to ageism, atypical presentation and less tendency to report negative affect among elderly people. Few studies have examined the impact of psychological stressors on medical burden in older adults. The current study has investigated the c...

Background and Objectives Blood reservation is done in many surgical operations because of the risk of bleeding. However, reservation should be based on a standard protocol so as to prevent blood loss. In this study, we deal with the ratio and causes of unused blood ordered from blood bank in elective surgeries in Rasoul-e-Akram hospital in Tehran....

This is the study of the prevalence of suicidal attempt and its demographic association in bipolar disorder (BPD) subjects in an emergency department in a non-Western culture. The subjects were 176 adults with DSM-IV BPD-type I (BPD-I). The mean age was 30.2 years and 66.2% of them were male. About 33.9% of the subjects made a suicidal attempt at l...

In a study on amyloid deposits in vertebral arteries, many elderly patients showed amyloid deposits in the perivascular tissue. These proved to be senile systemic amyloidosis of the transthyretin-type by immunohistochemistry. Amyloid deposits were also found in the arterial wall. These intramural amyloid deposits showed significant affinity to elas...

Burnout is a phenomenon in which the cumulative effects of a stressful work environment gradually overwhelm the defenses of staff members, forcing them to withdraw psychologically. This study compared the levels of burnout among nurses in different nursing specialties. MATERIALS and The sample of the study consisted of all the nurses working in all...

Background and Aim: Halothane and isoflurane are the most common anesthetic drugs in general anesthesia. Headache is the most common complication of patients after operation and the factors which cause it is inhalational anesthetics. The aim of this Study is detection of prevalence of headache after general anesthesia with halothane in comparison o...