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Ali Ihsan Parlar

Ali Ihsan Parlar
Kütahya Sağlık Bilimleri Üniversitesi · Cardiovascular Surgery

MD, PhD

About

77
Publications
14,095
Reads
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483
Citations
Citations since 2016
10 Research Items
201 Citations
2016201720182019202020212022010203040
2016201720182019202020212022010203040
2016201720182019202020212022010203040
2016201720182019202020212022010203040
Additional affiliations
November 2014 - November 2014
EACTS Academy Training
Position
  • Cardiac Surgeon
December 2012 - February 2015
Akut Kalp Damar Hospital
Position
  • Cardiovascular Surgery Resident
January 2012 - January 2012
Edwards EMEAC Headquarters Nyon, Switzerland
Position
  • Cardiac Surgeon
Education
September 1993 - June 2000
Hacettepe University
Field of study
  • Faculty of Medicine

Publications

Publications (77)
Article
The arterial revascularization procedure is still a challenging issue in Covid-19 associated limb ischemia. Herein we aimed to present a case of a 64 year-old woman with acute ischemic signs in upper extremity who was diagnosed as a probable Covid-19 case incidentally after admission. Although late admission and failed recurrent embolectomies lead...
Article
Pulmonary sequestration is defined as nonfunctioning lung tissue that is not in normal continuity with the tracheobronchial tree and that has a systemic arterial blood supply. Herein, we aimed to present a case of a 34-year-old male patient who had massive left-sided haemothorax on admission due to a giant intralobar pulmonary sequestration. An eme...
Article
Full-text available
Background: Postoperative atrial fibrillation (PoAF) is one of the most common complications to occur after open heart surgery. It has been shown that hypoalbuminemia accompanies some cardiovascular disorders. The present study evaluates the effects of pre-procedural albumin, blood urea nitrogen (BUN), and creatinine levels on PoAF. Methods: The da...
Article
Background: Postoperative atrial fibrillation (PoAF) is one of the most common complications to occur after open heart surgery. It has been shown that hypoalbuminemia accompanies some cardiovascular disorders. The present study evaluates the effects of pre-procedural albumin, blood urea nitrogen (BUN), and creatinine levels on PoAF. Methods: The...
Article
In elderly, high-risk surgical patients, sutureless aortic valve replacement (AVR) can often be an alternative to conventional AVR; shorter aortic cross-clamp and cardiopulmonary bypass times are the chief advantages. We compared the outcomes of sutureless AVR with those of conventional AVR in 70 elderly patients who underwent concomitant cardiac s...
Article
Background and aim: Acute pancreatitis is one of the less frequently diagnosed lethal abdominal complications. The incidence of early postoperative period hyperamylasaemia was reported to be 30-70% of patients who underwent coronary artery bypass grafting (CABG) with cardiopulmonary bypass (CPB). The mechanism of pancreatic enzyme elevation after...
Article
Background: The tricuspid valve is usually ignored and tricuspid interventions are mostly done in the context of other planned cardiac surgery. Isolated tricuspid reoperative procedure, especially tricuspid valve replacement (TVR) is very rare and carries a very high mortality rate. In this prospective study, clinical results of isolated TVR eithe...
Article
Background and aim of the study: Aortic valve replacement (AVR) with a sutureless valve is an innovative therapy in high-risk elderly patients. The study aim was to compare the early results of AVR using sutureless aortic valves or stentless aortic bioprostheses. Methods: A retrospective analysis was conducted of 55 patients who underwent AVR with...
Article
Background: Chronic mesenteric ischemia and carotid stenosis frequently have coexistent coronary artery disease. Myocardial ischemia is the most common cause of morbidity and mortality following revascularization of the peripheral arteries. The optimal treatment of concurrent mesenteric, carotid, and coronary disease is unknown. Case report: We...
Article
Full-text available
Background: This study aims to develop an easy and feasible risk scoring system by using right heart failure findings as well as New York Heart Association (NYHA) functional classification to predict the early and overall mortality rates in pericardiectomy. Methods: One third of 79 consecutive patients (50 males, 29 females; mean age 40.0±16.7 year...
Article
We aimed to investigate whether L-carnitine supplementation effects the neutrophil/lymphocyte ratio in patients undergoing coronary artery bypass grafting. The neutrophil/lymphocyte ratio is an inflammatory marker that has proven usefulness for predicting postoperative complications in coronary artery bypass surgery. A lot of studies concerning the...
Article
Konno aortoventriculoplasty (AVP) is performed for various types of left ventricular outflow tract obstruction. We report on a 32-year-old woman who had undergone double valve replacement five years earlier. She presented with increased interventricular septum thickness, small aortic root and gradient across the aortic mechanical valve. We performe...
Article
Full-text available
Objective: The aim of this study was to evaluate erectile function in males undergoing coronary artery bypass graft (CABG) while on two different adrenoceptor beta-blocker regimens, namely nebivolol and metoprolol. We hypothesize that the negative effects of cardiopulmonary bypass on erectile function may be possibly attenuated by preferring a vas...
Article
Hypertension is the leading cause of death among the different cardiovascular risk factors. Studies have found that differences in the prevalence of hypertension exist depending on gender, age, race, socio-demographic characteristics and geographical location. In this study, we aimed to determine the prevalence of hypertension according to gender a...
Article
In patients with respiratory failure and impairment of the left ventricle, arteriovenous extracorporeal membrane oxygenation (ECMO) offers further therapeutic options. Systemic anticoagulation is mandatory and heparin is routinely administrated. However, repeated exposure to heparin may cause heparin-induced thrombocytopenia (HIT) and carries a ris...
Article
Background: This study aims to investigate genetic polymorphisms in patients with mechanical heart valve dysfunction. Methods: Between January 1994 and December 2004, a total of 83 patients including 18 patients who were reoperated due to mechanical heart valve dysfunction (group 1), 15 patients with normal functions with lower international normal...
Article
Pulmonary hypertension (PHT) exacerbates the functions of both ventricles. This prospective, randomised study was planned to investigate the effects of PHT on kinetics of both ventricles and the septum. Twenty-five patients were randomly selected among the patients who had been planned to undergo mitral valve replacement (MVR) because of isolated m...
Article
Full-text available
Surgical aortic valve replacement is the gold standard of treatment for symptomatic severe aortic stenosis in all age groups. Transcatheter aortic valve implantation (TAVI), which is performed by senior interventional cardiologists in experienced centers, is an alternative therapy for patients considered to be at high risk for surgery. The aim of t...
Article
Left ventricular pseudoaneurysm is a rare, but lifethreatening complication occurring after acute myocardial infarction. Early diagnosis and surgery are critical for the patients’ recovery. An 80-year-old man was admitted to hospital with severe dyspnea. Coronary angiography and ventriculography showed a giant left ventricular pseudoaneurysm. Surgi...
Article
Objective: Postoperative atrial fibrillation (POAF) complicating coronary artery bypass grafting surgery (CABG) increases morbidity and stroke risk. Total atrial conduction time (PA-TDI duration) has been identified as an independent predictor of new-onset atrial fibrillation (AF). We aimed to assess whether PA-TDI duration is a predictor of AF af...
Article
Full-text available
Coroner artery fistula which is rare and congenital or acquired arise from whole coroner artery drainage all of cardiac chamber and great artery. Although coroner artery fistula is uncommon, it can cause significant mortality and morbidity rates. The article is presented which coroner artery disease and coroner-pulmonary artery fistula was accompli...
Article
Full-text available
Giant pseudoaneurysm of the ascending aorta is a rare but dreadful complication occurring several months or years after aortic surgery. Thoracic aortic aneurysms tend to be asymptomatic and were previously often diagnosed only after a complication such as dissection or rupture. We present a rare case of giant ascending aneurysm with Stanford type A...
Article
Full-text available
Post-traumatic tricuspid insufficiency is a rare complication of chest trauma. An 18-year-old male patient was injured in a bicycle accident from his abdominal and anterior chest wall. The tear on the inferior diaphragmatic surface of the heart was repaired with primary sutures by the attending surgeon. Eighteen years later, he was admitted to the...
Article
Full-text available
Postoperative pulmonary dysfunction following cardiopulmonary bypass (CPB) usually develops secondary to the inflammatory process with contact activation, hypothermia, operative trauma, general anesthesia, atelectasis, pain, and pulmonary ischemia/reperfusion due to cross-clamping. The aim of the present study was to evaluate the effects of an on-p...
Article
Full-text available
The present study aimed to compare the results of beating heart technique and conventional mitral valve surgery (MVS). Three hundred and nineteen patients who underwent MVS between April 2005 and December 2006 were enrolled in the study. While 125 patients underwent beating heart MVS (group 1), the conventional approach was used for 194 patients (g...
Article
The best management regimen for patients with coronary artery disease requiring surgery and bilateral total internal carotid artery occlusion remains controversial. A 61-year-old male patient presented with unstable angina pectoris. His medical history revealed that he had a cerebrovascular accident 11 years ago. On physical examination, he had dys...
Article
Isolated tricuspid valve replacement is not a common operation and the choice between mechanical and biologic prostheses remains controversial. When mechanical prosthesis are used, anticoagulant therapy is mandatory. In this article, we report a 21-years-old female patient who survived 15-years without anticoagulation following tricuspid valve repl...
Article
Full-text available
Traditionally, reoperations for mitral valve replacement are carried out under cardioplegic arrest with cross-clamping of the ascending aorta via a median sternotomy. In this case, the mitral valve replacement operation was performed with an on-pump beating heart technique without cross-clamping the aorta and via a right thoracotomy because of diff...
Article
Background: The purpose of this study was to evaluate the safety and efficacy of amiodarone in the treatment of newonset atrial fibrillation (AF) after coronary artery bypass grafting (CABG) surgery. Methods: The study included 20 patients (15 males, 5 females; mean age 64±9 years; range 43 to 79 years) who underwent CABG surgery for ischemic heart...
Article
Full-text available
Isolated tricuspid valve replacement, which is not a common operation, is associated with poor short and long-term results, and the postoperative morbidity and mortality rates are high. The main reason for these adverse effects is the acute manifestation of chronic right heart failure. To treat right heart failure, we used levosimendan for its inot...
Article
Full-text available
Weaning from cardiopulmonary bypass is the most important stage during mitral valve surgery, especially in patients with severe pulmonary hypertension. We report two patients with severe pulmonary hypertension who were operated on because of valvular heart disease. To reduce the pulmonary artery pressure, levosimendan was used because of its vasodi...
Article
The incidence of residual opening after repair of postmyocardial infarction ventricular septal defect (VSD) was reported to be 10% to 25%. Redo surgery with remedial sternotomy is more complex than primary surgery and is consequently associated with higher mortality and morbidity due to the myocardial and patent coronary grafts injury during perica...
Article
Cardiac reperfusion injury is a well-described complication occurring after ischemia or following cardioplegic arrest. Various strategies have been developed to prevent ischemic reperfusion injury. The aim of this study was to assess the efficacy and applicability of the on-pump beating heart mitral valve surgery without cross-clamping the aorta in...
Article
Today, mitral valve replacement is performed under cardioplegic arrest with cross-clamping of the ascending aorta. In the case reported here, mitral valve replacement was performed with an on-pump beating heart technique without cross-clamping the aorta because of diffuse adhesion around the tube graft. A 36-year-old man had undergone a Bentall ope...
Article
Le déficit neurologique post-opératoire est la complication la plus grave après traitement d'un anévrysme de l'aorte thoraco-abdominale. Notre but était de déterminer si le nebivolol avait un effet protecteur au cours de l'ischémie ou de la reperfusion et quel était le mécanisme de protection le plus efficace en inhibant la production d'oxyde nitri...
Article
El déficit neurológico postoperatorio es la complicación más devastadora después de la corrección de un aneurisma aórtico toracoabdominal. El objetivo del presente estudio fue investigar si el nebivolol tiene efectos protectores durante la isquemia o reperfusión y el mecanismo de protección más eficaz a través de la inhibición de la liberación de ó...
Article
Postoperative neurologic deficit is the most devastating complication after thoracoabdominal aortic aneurysm repair. Our aim was to investigate whether nebivolol has protective effects during ischemia or reperfusion and the most effective mechanism of protection via inhibiting nitric oxide (NO) release with an NO synthase inhibitor in an experiment...
Article
Postoperative neurologic deficit is the most devastating complication after surgical thoracic aorta repair. Cerebrospinal fluid drainage and some medications are used for spinal cord protection during and after the operation. A 25-year-old patient applied to our clinic with a traumatic descending aortic aneurysm. We performed a surgical repair for...
Article
Comparison of neurological parameters in patients undergoing prosthetic heart valve replacement with two operating techniques-either cardioplegic arrest of the heart under hypothermic cardiopulmonary bypass (CPB) or the heart beating on normothermic bypass, with or without cross-clamping the aorta, without cardioplegic arrest. methods: Fifty valvul...
Article
Although neurologic outcome after cardiac surgery is well-established, neurocognitive functions after beating heart mitral valve replacement still needs to be elucidated. The aim of this study was to compare preoperative and postoperative neurocognitive functions in patients who underwent beating heart mitral valve replacement on cardiopulmonary by...
Article
Conventional mitral valve replacement (MVR) is carried out under cardioplegic arrest with cross-clamping of the ascending aorta during cardiopulmonary bypass. In this case, MVR was performed with on-pump beating heart technique without cross-clamping the aorta because of the diffuse adhesion around the ascending aorta, and tube graft presence betwe...
Article
The internal thoracic artery (ITA) is the gold-standard conduit for coronary artery bypass surgery. It stays patent well in the long-term period, and this evidence is directly related to the superior later outcome in terms of longevity. Coronary artery bypass grafting with multiarterial grafts can be performed safely, and better long-term result ca...
Article
Le but de cette étude expérimentale était d'étudier si le diméthylsulfoxyde (DMSO) a des effets protecteurs sur l'ischémie reperfusion médullaire (I/R). Des lapins New Zealand ont été utilisés pour l'étude. En plus du groupe contrôle, le groupe étudié a reçu 0.1 mL/kg de DMSO avant l'ischémie. Des prises de sang ont été prélevées pour doser les nit...
Article
Full-text available
We present a Turkish family and their 6 children, consecutively affected by Ellis-van Creveld (EVC) Syndrome. Four of the affected children died in the postnatal period, and 2 of them had been admitted to the pediatric cardiology department for their cardiologic evaluation. Since they had the features of the EVC Syndrome, linkage analysis was perfo...
Article
The aim of this experimental study was to investigate whether dimethylsulfoxide (DMSO) has protective effects on spinal cord ischemia-reperfusion (I/R) injury. New Zealand rabbits were enrolled in the study. In addition to the control group, the study group received 0.1 mL/kg DMSO prior to ischemia. Blood samples were taken to obtain nitrite-nitrat...
Article
El objetivo del presente estudio experimental fue investigar si el dimetilsulfóxido (DMSO) produce efectos protectores sobre la lesión de isquemia-reperfusión (I/R) de la médula espinal. Se incluyeron en el estudio conejos de Nueva Zelanda. Además del grupo de control, el grupo de estudio recibió 0,1 ml/kg de DMSO antes de la isquemia. Se obtuviero...
Article
Purpose: We purposed to evaluate the management and morbidity and mortality in the penetrating carotid artery trauma patients. Method: Between 1990-2006, 7 patients who admitted to hospital by penetrating carotid artery trauma were evaluated preoperatively and postoperative mortality-morbidity results retrospectively. Results: Five of seven patient...
Article
The new calcium sensitizer, levosimendan, not only acts as a positive inotropic agent but also, vasodilates both venules and arterioles. The aim of this experimental study was to investigate whether levosimendan has protective effects on spinal cord ischemia-reperfusion injury. Twelve New Zealand rabbits were enrolled in this study. In addition to...
Article
The aim of this study was to investigate the response of heart to stress according to the size of the prosthetic valve in patients who had undergone mitral valve replacement by using dobutamine stress echocardiography (DSE) and to evaluate the relationship between the size of the prosthetic valve and cardiac recovery-remodeling process. Thirty-nine...
Article
Full-text available
The mechanism of the vasorelaxation to levosimendan varies depending on the vascular bed and species studied. Here, we examined the vasorelaxation to levosimendan as well as its modification by various potassium channel antagonists in human internal mammary artery (IMA) obtained from male and female patients. IMA grafts were supplied from 27 male a...
Article
Background: We aimed to evaluate results of using tandem PTA and surgical vascular interventions for multilevel occlusive peripheral arterial diseases. Materials and Methods: Retrospectively 22 patients who had combined PTA and surgical revascularization treatment between 2000 and 2006 were included to the study. Twenty-two patients with 28 extremi...
Article
Reoperations have become of increasing frequency in the last four decades. Redo surgery is more complex than primary surgery and is associated with higher mortality and morbidity. We present our immediate and mid-term results of mitral and aortic prosthetic valve replacement undertaken with beating heart technique. The prospective study included 26...
Article
Aortic root surgery has traditionally been performed with an arrested and cooled heart using cardioplegia. A new technique of myocardial protection was utilized in the treatment of ascending aortic aneurysm with severe aortic valve regurgitation requiring aortic root replacement with the Cabrol technique. Retrograde and antegrade perfusion of the h...
Article
Objective: The study aim was to investigate the effect of blood glucose level on atherosclerotic lesion distribution and the contribution to the operative mortality/morbidity in diabetic patients who underwent coronary artery bypass grafting (CABG). Methods: Between 1986-2003, a total of 2095 patients with diabetes mellitus underwent CABG. The a...
Article
The aim of this study was to assess the efficacy and applicability of on-pump beating heart aortic valve replacement with retrograde coronary sinus (CS) warm blood perfusion. The prospective study included 14 consecutive patients who underwent aortic valve replacement with mechanical prosthesis using retrograde CS perfusion. The operative variables...
Article
This study was planned to evaluate patients with penetrating cardiac injury. Twenty-two patients had cardiac injury among twenty-five patients who had been referred to our hospital with a suspicion of this diagnosis. Data of the patients were retrospectively evaluated. Echocardiography could be performed in 11 patients with stable haemodynamics and...
Article
Background: We investigated whether some endothelial, thrombotic, and antithrombotic markers differed between young (age <35 years) and elderly patients (age ≥60 years) who were candidates for coronary artery bypass grafting following the diagnosis of coronary artery disease (CAD). Methods: Thirty patients <35 years of age (mean age 31.0±0.3 years)...
Article
Aortic dissection is the most common acute illness of the aorta with a high mortality. Early detection and proper treatment is important for improving survival. The severity and consequences of a dissection and therapeutic approach are associated with the physical characteristic and anatomic location of the tear as well as the underlying patient ph...
Article
The aim of this study was to assess the efficacy and applicability of on-pump beating heart mitral valve replacement with Sorin Bicarbon prosthesis using retrograde coronary sinus perfusion. The prospective study included 17 consecutive patients who underwent mitral valve replacement with Sorin Bicarbon prosthesis using retrograde coronary sinus pe...
Article
Repair of post infarction posterior ventricular septal defect has generally been performed with a ventriculotomy through the infarcted zone. This approach has a significant mortality and morbidity due to haemorrhage, extension of infarction or further compromise of ventricular function secondary to suture placement. We present a case with delayed r...
Article
The present study aims to examine whether resveratrol, a natural antioxidant present in red wine, restores the tolerance to nitroglycerin (GTN) on isolated human internal mammary artery (IMA), using an in vitro model of nitrate tolerance. IMA rings were obtained from 53 male patients undergoing coronary bypass operation. Nitrate tolerance was induc...
Article
Genetic bases for novel prothrombotic, inflammatory risk factors may play a role in the early onset of coronary artery disease. Twenty-one patients below 35 years of age who underwent coronary bypass grafting between 2002 and 2004 constituted the study group and were compared with 50 healthy, age and sex-matched controls. Gene analysis for genetic...