Ali S Hafez

• MD, PhD
• Université de Montréal

Vascular disorders in the eye may have an important role in the pathogenesis of glaucomatous optic neuropathy. A primary requirement for understanding such vascular disorders is the ability to precisely and reliably evaluate the state of ocular perfusion in health and disease. This has led to the exploration of many innovative and diverse technique...

A great body of evidence suggests that abnormal ocular blood flow contributes to the pathophysiology of open-angle glaucoma. Large clinical studies have linked low ocular perfusion pressure to the prevalence, incidence, and progression of glaucoma. Reduced blood flow has been reported in the retina, optic nerve, choroid and retrobulbar vasculature...

To investigate changes in optic nerve head topography and blood flow after therapeutic intraocular pressure reduction and to correlate them with central corneal thickness. Sixteen patients with open-angle glaucoma and 16 patients with ocular hypertension underwent Heidelberg retina tomography and scanning laser Doppler flowmetry in 1 eye before and...

To correlate finger blood flow and changes in optic nerve head (ONH) blood flow following therapeutic intraocular pressure (IOP) reduction in open-angle glaucoma (OAG) and ocular hypertension (OHT). Seventeen open-angle glaucoma patients and nineteen ocular hypertension patients underwent therapeutic IOP reduction followed by a minimum of 4 weeks o...

To compare optic nerve head (ONH) and peripapillary retinal blood flow in subjects with open-angle glaucoma (OAG), ocular hypertension (OHT), and normal eyes (NOR) using full-field perfusion analysis of scanning laser Doppler flowmetry (SLDF) images. Prospective, nonrandomized clinical trial. Twenty uncontrolled OAG patients, 20 uncontrolled OHT pa...

To evaluate the reproducibility of full-field perfusion analysis using scanning laser Doppler flowmetry (SLDF) for perfusion measurements of the neuroretinal rim of the optic nerve head and the peripapillary retina in patients with open-angle glaucoma or ocular hypertension, and in normal subjects. SLDF perfusion measurements of the neuroretinal ri...

To detect and quantify changes in optic nerve head (ONH) and peripapillary retinal blood flow by scanning laser Doppler flowmetry (SLDF) in open-angle glaucoma (OAG) and ocular hypertension (OHT) after therapeutic intraocular pressure (IOP) reduction. Prospective, nonrandomized, self-controlled trial. Twenty patients with OAG and 20 patients with O...