Ali Al-bayati

• M.B.Ch.B, MSc. PhD in Molecular Diabetes
• Professor (Associate) at Mustansiriyah University

Hypothyroidism is one of the common endocrine disorders that is associated with cardiovascular diseases, it is more common in women with female: male ratio reaches up to 6:1. Hypothyroidism could be regarded as inflammatory condition and Systemic inflammation was emerged as a risk factor for cardiovascular disease. To study the association of serum...

Background and objectives: Non-transfusion dependent thalassemia (NTDT) characterized by an increase iron overload with end-organ damage as a consequence. The aim of the current study is to determine the correlation between factors that control and reflect excess iron, (serum hepcidin and ferritin levels), in Iraqi adult patients with non-transfusi...

Abstract Thyroid diseases are a common endocrine disorder, and thyroid hormones physiologically are well-known to have direct and indirect effects on metabolic abnormalities. Disorders of carbohydrates (glucose) metabolism are frequently reported in both hypothyroidism and hyperthyroidism. This review considered to examine and analyze the role of t...

Diabetes mellitus is the commonest endocrine and metabolic disorders. Patients with diabetes have about double risk to develop severe COVID-19. The severity of COVID-19 shown to be associated with dysregulation of glycemic control in diabetes. This review focus on the most obvious contributing factors linking these nowadays the two common pandemics...

Introduction and Aim: Two major clinical forms of acute coronary syndrome (ACS) were categorized; acute myocardial infarction (MI) showing ST-segment elevation (STEMI) with ECG, the other non-ST-segment elevation (NSTEMI). This study was designed using a new generation of high sensitivity cardiac troponin T2 (hscTnT2) in patients with acute coronar...

Background and aim: poly cystic ovarian syndrome is a common reproductive dysfunction associated with metabolic dysregulation. This study aims to investigate the metabolic effects of Anti-Müllerian Hormone (AMH) and Myonectin in Iraqi women with PCOS. Patients and methods: A case-control study was conducted in Baghdad, Iraq. The overall sample size...

Background and aim: Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disorder affects women in the reproductive age group. PCOS is frequently associated with Obesity. A prominent interplay was noticed between BMI value and hormonal changes accompanying PCOS. The study aims to elucidate role of hormonal factor Anti-Müllerian horm...

Background As a continuation of earlier laboratory research and its findings, we are studying the effects of biostimulation and alteration on human blood plasma to improve blood circulation in blood vessels, treat some infections, and treat various diseases, including blood protein-related ones. Methods Blood samples were collected through venipun...

Background Elabela is a newly discovered peptide hormone that has been implicated in liver disease. Objective The main objective of the current work is to assess whether variations in blood Elabela levels among chronic hepatitis C (CHC) patients from Iraq might be used as a biomarker for liver fibrosis. Materials and Methods A case-control study...

Background: The rise in the burden of type 2 diabetes mellitus (T2DM) is causing global concern, especially in low-income countries. In addition, the American Diabetes Association recommends the use of DPP-4 inhibitors in combination with metformin. However, no studies using teneligliptin with or without metformin have been conducted in Iraqi patie...

Introduction and Aim: Evaluation of the profile of immunological and inflammatory cytokines, IL-6, IL-2 and TNF? in acute myeloid leukemia (AML) and chronic myeloid leukemia (CML) patients compared their level with healthy controls, and assessment of the association of these cytokines with clinical and hematological variables. Patients and Methods:...

Vitamin D, a fat-soluble vitamin, acts as steroid hormone and its main action is to modulate the levels of calcium and phosphorus and to then regulate bone metabolism. It is produced by conversion of subcutaneous cholesterol in the skin upon exposure to ultraviolet B (UVB) radiation, and acts on the regulation of expression of a large number of gen...

Abstract Objective: To assess the risk factors associated with diabetes on parameters of diabetic nephropathy represented by albuminuria level. Methods: The case-control cross-sectional study was conducted at the National Diabetes Centre for Treatment and Research, Al-Mustansiriyah University, Baghdad, Iraq, from October 2019 to March 2020, and com...

Objective: To determine and compare serum vitamin D and cortisol hormone levels in hypothyroidism patients and healthy controls, and to assess the correlation of vitamin D with related parameters. Methods: The case-control study was conducted from March to October 2019 at the National Diabetic and Endocrine Centre, Mustansiriyah University, Bagh...

Diabetes mellitus is the commonest endocrine and metabolic disorders. Patients with diabetes have about double risk to develop severe COVID-19. The severity of COVID-19 shown to be associated with dysregulation of glycemic control in diabetes. This review focus on the most obvious contributing factors linking these nowadays the two common pandemics...

Background and aim: Hyperbilirubinemia is an elevation of the bilirubin levels in blood of newborn babiesthat presented as jaundice. This study aimed to evaluate the levels of important of immunological systemproteins (IgG, IgM, IgA, C3 and C4) in both newborn babies with severe hyperbilirubinemia and healthycontrols.Methods: Thirty (30) full-term...

Hyper-coagulability (elevated thrombin) is a feature of T2D. There is an emerging evidence of a correlation between the genetic basis of hypercoagulation and T2D. We hypothesized that thrombin affects insulin activity and/or exercise responses in human skeletal muscle cells which could link the hypercoagulability and insulin resistance in T2D. Furt...

Background and aim: Hyperbilirubinemia is an elevation of the bilirubin levels in blood of newborn babies that presented as jaundice. This study aimed to evaluate the levels of important of immunological system proteins (IgG, IgM, IgA, C3 and C4) in both newborn babies with severe hyperbilirubinemia and healthy controls.

Aims: Skeletal muscle insulin resistance is a characteristic feature of type 2 diabetes. The aim of this study was to examine the effect of contraction on insulin action using electrical pulse stimulation (EPS) in cultured skeletal muscle cells from insulin resistant type 2 diabetic patients. Methods: Skeletal muscle cell cultures were establish...

P137 The responses to an in vitro exercise system are impaired in cultured human muscle cells from patients with Type 2 diabetes A Al-Bayati, A Brown and M Walker Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK Background and aim: Skeletal muscle insulin resistance is the major molecular abnormality in Type 2 diabe...

Abstract: Introduction: Thrombin is one of the major substrate in the blood coagulation process with other secretory and developmental functions. In type 2 diabetes, patients seem to be a hyper-coagulable (elevated thrombin) with high risk of thrombotic and vascular events. These observations reveal that there is a strong association between metabo...