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Alfonso Martín Cabello-Vílchez

Alfonso Martín Cabello-Vílchez
Universidad Privada Norbert Wiener. Instituto de Medicina Tropical "Alexander von Humboldt". Universidad La Laguna

MSc, PhD

About

36
Publications
17,640
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420
Citations
Citations since 2016
18 Research Items
295 Citations
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201620172018201920202021202201020304050
Introduction
Pathogenicity of free-living amoebae and its symbiotic association with Mycobacterium sp. Free-living amoebae potentially pathogenic Isolated Nasal Mucosa.

Publications

Publications (36)
Article
Full-text available
Mycobacterium gordonae is a nontuberculous mycobacterium found in diverse environments and is considered an opportunistic pathogen in immunocompro-mised patients. We report the draft genome sequence of a Mycobacterium gordonae strain isolated from a free-living amoeba found in a nosocomial environment in Lima, Peru.
Article
Full-text available
The genus Naegleria consists of free-living amoebae widely distributed worldwide in soil and freshwater habitats. Primary amoebic meningoencephalitis (PAM) is an uncommon and most likely fatal disease. The incubation period is approximately 7 days. The first symptoms are headache, nasal congestion, fever, vomiting, stiff neck within 3–4 days after...
Presentation
Full-text available
CV
Article
Full-text available
Infections by free-living amoebas cause cutaneous and neurological compromise. These conditions have a low frequency, but a high lethality more than 98%. Generally, the clinical picture is nonspecific; the laboratory tests don´t help, so it represents a diagnostic and therapeutic challenge. In this report, we present the case of a 21-year-old patie...
Article
Full-text available
Introduction Balamuthia mandrillaris is a free-living amoebae (FLA) are parasites within both humans and animals causing a wide range of sick and act as vehicles for many microorganisms how mycobacterium. Case Presentation We present two young male patients, who died with highly unusual mixed infections involving Balamuthia or Balamuthia-like amoe...
Article
Full-text available
Granulomatous amoebic encephalitis caused by free‐living amoebae is a rare condition that is difficult to diagnose and hard to treat, generally being fatal. Anti‐amoebic treatment is often delayed because clinical signs and symptoms may hide the probable causing agent misleading the appropriate diagnostic test. There are four genera of free‐living...
Article
Full-text available
Las amebas de vida libre (AVL) se encuentran ampliamente distribuidas en la naturaleza, siendo Acanthamoeba spp. el género más aislado del suelo, aire, aguas tratadas para consumo, agua de mar, lagos y aguas termales. El presente trabajo aborda las características de Acanthamoeba spp., su biología, las patologías que afectan a humanos; además, el d...
Chapter
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“Water pollution in Peru is as old as the existence of cities, because rivers and seas have served and continue to serve as final disposal points for sewage” (ONERN, 1985).
Article
Full-text available
Abstract: Free-living amoebas are eukaryotic microorganisms that inhabit many environments naturally. These amoebas are aerobic microorganisms, consuming bacteria, yeasts and other eukaryotes. There are three species frequently reported in humans, the first two are: Acanthamoeba sp. (T-4) and Balamuthia mandrillaris. The third amoeba is: Naegleria...
Poster
Full-text available
Free-living amoebae (FLA) are widely distributed environmental protozoa, mostly seen in water-and soil-related habitats. In this study, we have looked for free-living amoebae in Andean lakes. There are two prominent high-altitude lakes in Peru: Titicaca like , coordinates 15°45' South, 69°25 West, elevation 3,812 m, surface 8,380 km², and Lake Juní...
Article
Full-text available
Introducción: Las infecciones por micobacterias pueden causar lesiones cutáneas y pulmonares; las micobacterias pueden hallarse en fuentes de agua intrahospitalarias, pudiendo llegar a los pacientes inmunosuprimidos y provocar enfermedades severas. Objetivo: Aislar y caracterizar micobacterias no tuberculosas en el sistema de distribución de agua e...
Conference Paper
Full-text available
Las amebas de vida libre por lo general no son patógenas. Sin embargo, algunas especies si lo son para el hombre y animales. Causan una mortalidad del 98%.
Article
Full-text available
Introducción: Las infecciones por micobacterias pueden causar lesiones cutáneas y pulmonares; las micobacterias pueden hallarse en fuentes de agua intrahospitalarias, pudiendo llegar a los pacientes inmunosuprimidos y provocar enfermedades severas. Objetivo: Aislar y caracterizar micobacterias no tuberculosas en el sistema de distribución de agua...
Poster
Full-text available
Introduction: Amoebic infections of the central nervous system (CNS) are very rare, and usually fatal. Two main forms of CNS infection caused by free-living amoebas are recognized: (1) primary amoebic meningoencephalitis due to Naegleria fowleri; (2) granulomatous amoebic meningoencephalitis (GAM) caused by Acantamoeba spp., Balamuthia mandrillaris...
Article
Full-text available
Resumen Las amebas de vida libre son microorganismos abundantes en el suelo y agua en todo el planeta. Algunas especies de estas amebas son capaces de causar muerte en el ser humano y animales, así como Naegleria fowleri (N. fowleri), Acanthamoeba sp. T4 principalmente y Balamuthia mandrillaris (B. mandrillaris). El 98% de los casos reportados en e...
Article
Full-text available
Las amebas de vida libre (AVL) se encuentran ampliamente distribuidas en la naturaleza, siendo Acanthamoeba spp. el género más aislado del suelo, aire, aguas tratadas para consumo, agua de mar, lagos y aguas termales. El presente trabajo aborda las características de Acanthamoeba spp., su biología, las patologías que afectan a humanos; además, el d...
Poster
Full-text available
Introduction: The free-living amoebae (FLA), are widely distributed in nature, with several species that have been isolated from soil, air, water supply, sea water, hot springs, lakes, etc. (Martínez, 1985) Studies in Peru are limited, being mostly case reports. Skin characteristics are shown to be consistent with Acanthamoeba or Balamuthia. Anothe...
Article
Full-text available
Free living amoebae (FLA) are ubiquitous protozoa, which may behave as parasites under certain conditions. Four genera are recognized as causal agents of infections in humans and animals: Naegleria, Sappinia, Acanthamoeba and Balamuthia. This work determines the presence of FLA in combination shower units and employs molecular biology for the chara...
Article
Full-text available
Balamuthia mandrillaris is an opportunistic free-living amoeba that has been reported to cause skin lesions and the fatal Balamuthia amoebic encephalitis (BAE) in humans and other animals. Currently, around 200 human BAE cases have been reported worldwide, although this number is considered to be underestimated. The highest number of BAE cases has...
Article
Full-text available
In March 2010, a 35 year-old HIV/AIDS female patient was admitted to hospital to start treatment with Highly Active Antiretroviral Therapy (HAART) since during a routine control a dramatic decrease in the CD4+ levels was detected. At this stage, a nasal swab from each nostril was collected from the patient to include it in the samples for the case...
Article
Free-living Amoebae of Acanthamoeba genus include non-pathogenic and pathogenic strains that are currently classified in 18 different genotypes, T1-T18. In this study, a survey was carried out to evaluate the presence of Acanthamoeba strains in soil samples collected between 2012 and 2013 in Gran Canaria Island, Canary Islands, Spain. Samples were...
Article
Full-text available
Pathogenic strains of Acanthamoeba genus are the causative agents of fatal granulomatous amoebic encephalitis and a serious sight-threatening infection of the eye known as Acanthamoeba keratitis. In a previous study, Acanthamoeba strains were isolated from nasal swabs collected from healthy individuals in Peru. In the present study, the pathogenic...
Article
Full-text available
Free Living Amoebae (FLA) of Acanthamoeba genus are widely distributed in the environment and can be found in the air, soil and water; and have also been isolated from air-conditioning units. In humans, they are causative agents of a sight-threating infection of the cornea, Acanthamoeba keratitis (AK) and a fatal infection of the central nervous sy...
Article
Full-text available
Balamuthia mandrillaris is an opportunistic, free-living amoeba that can cause skin lesions and the typically fatal Balamuthia amoebic encephalitis (BAE) both in immunocompromised and immunocompetent individuals. Available data for BAE cases indicate that this disease is difficult to detect because knowledge of predisposing factors is lacking, caus...
Article
Full-text available
Introduction. Diffusely adherent E. coli (DAEC) is the sixth recognized group of diarrheagenic E. coli. However, its association with diarrhea remains controversial. Variability in the adherence patterns of clinical strains is unknown. Objectives. To compare the adherence patterns between strains isolated from children with and without diarrhea. Ma...
Article
Full-text available
Diffusely adherent E. coli (DAEC) is the sixth recognized group of diarrheagenic E. coli. However, its association with diarrhea remains controversial. Variability in the adherence patterns of clinical strains is unknown. To compare the adherence patterns between strains isolated from children with and without diarrhea. A total of 31 DAEC strains w...
Article
Full-text available
The purpose of this study was to determine the presence and quantity of fecal leukocytes in children infected with diarrheagenic Escherichia coli and to compare these levels between diarrhea and control cases. We analyzed 1,474 stool samples from 935 diarrhea episodes and 539 from healthy controls of a cohort study of children younger than 2 years...

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Projects

Projects (3)
Project
Este proyecto busca aumentar el conocimiento de los bofedales en diferentes campos: flora y fauna (incluyendo protozoarios) y las características de componentes abióticos como el agua y el suelo. Se evaluarán diferentes tipos de metodologías en distintas comunidades vegetales de varias regiones del país. Los resultados permitirán tener herramientas útiles para conservación, manejo y/o restauración. Este es un proyecto abierto, están invitados a participar todos los interesados. Para mayores detalles, enviar un correo a mmaldonado@corbidi.org
Project
Currently, we develop research in clinical diagnosis from free-living amoebae. Determine the presence or absence amoeba in water sources and lagoons and Lima pools.