Alexis Lacout

AURILLAC Radiologie · 15

La maladie de Lyme est causée par une infection par la bactérie Borrelia burgdorferi. D'autres espèces de Borrelia ont été découvertes et provoquent des maladies similaires. La première espèce décrite, Borrelia burgdorferi sensu stricto, a été isolée aux États-Unis. La maladie de Lyme est une grande simulatrice pouvant ressembler à de nombreuses ma...

Lyme disease is caused by an infection with the bacterium Borrelia burgdorferi. Other Borrelia species have been discovered and cause similar diseases. The first species described, Borrelia burgdorferi sensu stricto, was isolated in the United States. Lyme disease is a great imitator, resembling many conditions, including autoimmune diseases. The d...

The pharmaceutical industry regularly uses highly biased, unreliable studies to oversell their drugs. In recent years, a growing number of scientific publications studying innovative pharmaceutical products have included studies with such significant biases as to invalidate the results promoted by the authors. Remdesivir caught our attention becaus...

Indwelling port catheters are nowadays the main etiology of be- nign superior vena cava (SVC) syndrome. SVC obstruction increa- ses the venous blood pressure upstream, and subsequently into the arterio-venous sac malformations of the nasal cavity, leading to the high risk of recurrent epistaxis in hereditary hemorrhagic telan- giectasia (HHT) patie...

Despite a peer review process prior to being published in Biomedicine & Pharmacotherapy, Pradelle et al, "Deaths induced by compassionate use of hydroxychloroquine (HCQ) during the first COVID-19 wave: an estimate" is cluttered with several scientific integrity issues, one of them being the lack of validation against real life data. Mathematical mo...

La maladie de Lyme, transmise par les tiques, est une maladie particulièrement complexe, au diagnostic difficile. Cette infection engendre beaucoup d'errance médicale et de mystification autour de ce qui est pourtant une réalité : des dizaines de milliers de personnes sont touchées par la maladie en France. Le docteur Alexis Lacout, vous donne les...

Le diagnostic de maladie de Lyme ou de maladie vectorielle à tique est difficile en raison d’un polymorphisme clinique, du manque de fiabilité de la biologie et d’une prise en charge parfois déroutante. Souvent, les patients atteints de maladie de Lyme dans sa forme persistante ne sont ni diagnostiqués ni traités et se trouvent en errance parfois d...

This is the case of a 40-year-old immunocompetent, female patient presenting with a "polymorphic persistent syndrome after a possible tick bite" (SPPT), a syndrome officially recognized by the French High Authority for Health (HAS). This patient presented with polymorphic symptoms and was unable to walk without a walker. Only ceftriaxone was effect...

Citation: Alexis Lacout, Christian Perronne. Effect of Flubendazole, with Jarish-Herxheimer Reactions Followed by Cure, in A Patient with A Polymorphic Persistent Syndrome Suggestive of Chronic Lyme Disease: A Sign of Parasitic Disease. Archives of Microbiology and Immunology. 8 (2024): 96-100. Abstract This paper discusses the case of a 40-year-ol...

A cohort of 30,423 Covid-19 patients treated between March 2020 and December 2021 at the IHU-Méditerranée Infection in Marseille (France) was retrospectively analyzed in terms of treatment attempted and disease worsening factors to quantify efficacy with respect to the composite endpoint of transfer to intensive care unit or death, within a couple...

A cohort of 30,423 Covid-19 patients treated between March 2020 and December 2021 at the IHU-Méditerranée Infection in Marseille (France) was retrospectively analyzed in terms of treatment attempted and disease worsening factors to quantify vaccination efficacy with respect to the composite endpoint of transfer to intensive care unit or death, with...

Introduction Ticks are frequently polyinfected and can thus transmit numerous microorganisms. A large number of bacteria, parasites and viruses are transmitted by tick bites and could cause different signs and symptoms in patients. The main goal of this study was to search for these numerous microorganisms in patients presenting with persistent pol...

Background: Borrelia species are divided into three groups depending on the induced disease and the tick vector. Borrelia miyamotoi is a relapsing fever Borrelia but can induce symptoms related to Lyme disease. Discovered in 1995, it is found in ticks around the world. In France, this species of Borrelia has been isolated in ticks and rodents, but...

Introduction: Distant metastases of papillary thyroid cancers are rare. Most common metastatic sites include bone and lung, whereas metastases to brain, eye, breast, liver, kidney, muscle, and skin are infrequent and almost always appear in advanced-stage tumor disease. Metastases to ovary and/or uterus are even scarcer. We report herein a very ex...

38th Annual Meeting of the European-Society-for-Radiotherapy-and-Oncology (ESTRO), Milan, ITALY, APR 26-30, 2019

Background and purpose: The objective of this project was to define consensus guidelines for delineating brainstem substructures (dorsal vagal complex, including the area postrema) involved in radiation-induced nausea and vomiting (RINV). The three parts of the brainstem are rarely delineated, so this study was also an opportunity to find a consen...

Lyme disease is the most frequently reported zoonotic tick-borne disease worldwide, and the number of infected humans is increasing. Lyme disease (or Lyme borreliosis) is an affection caused by the spirochete Borrelia burgdorferi, sensu lato. Lyme disease is also reported as a variety of misleading clinical symptomatologies. Infected patient's bloo...

Lyme disease is an affection caused by a spirochete infection called Borrelia Burgdorferi which may harbor a varied and misleading clinical symptomatology. The serology tests commonly used for diagnosis show a wide sensitivity varying from 34% to 70,5%, leaving many infected patients with false negative tests. Alternative techniques such as polymer...

Formal serology in patients presenting with presumptive Lyme disease symptoms is not sufficient to definitively rule out Lyme disease. A broader laboratory panel approach such as including a polymerase chain reaction (PCR) or ELISPOT test can be more sensitive and specific. The search for an antibody intrathecal production may not be essential to t...

Introduction: This study aimed at comparing thyroid cancer staging when taking into account the differences between the "T" assessment" using ultrasound (US) and histopathological measurements. Material and methods: This retrospective study included all consecutive differentiated follicular thyroid cancer (DTC) and medullary thyroid cancer (MTC)...

Bronchiolitis obliterans with organizing pneumonia is an inflammatory reaction that can occur as a consequence of various pulmonary affections. Radiotherapy is not the sole and systematic cause of bronchiolitis obliterans with organizing pneumonia. Radiation-induced should not be confused with post-radiation, dose-dependent, inflammatory pulmonary...

Spondyloarthritis refers to a group of chronic inflammatory rheumatic diseases that predominantly affects the axial skeleton, causing pain and stiffness. Human bone is highly dynamic organ that interacts with a wide array cells and tissues. Process of bone remodelling relies on a delicate balance between bone formation and bone resorption, orchestr...

Also known as Rendu-Osler-Weber syndrome, hereditary haemorrhagic telangiectasia (HHT) is a rare autosomal dominant disorder that leads to abnormal blood vessel formation in the skin, mucous membranes and often in organs such as lungs, liver and brain.1 At clinical inspection, patients frequently present with skin, lip and/or tongue telangiectasias...

Modern radiation therapy techniques are characterized by high conformality to tumor volumes and steep dose gradients to spare normal organs. These techniques require accurate clinical target volume definitions and rigorous assessment of set up uncertainties using image guidance, a concept called image-guided radiation therapy. Due to alteration of...

Diagnosis of venous jugular invasion by means of traditional imaging is very rarely reported in the literature. Doppler ultrasound definitively helps to diagnose the tumor thrombus, the extent, and helps in redefining the TNM stage of such an aggressive thyroid tumor.

Qu’avez-vous retenu de cet article ? Testez si vous avez assimilé les points importants de cet article en répondant à ce questionnaire sous forme de QCM.

L’aspect macroscopique du carcinome papillaire de la thyroïde reflète la présence de papilles tumorales microscopiques et suggère une organisation fractale où chacune des parties ressemble à l’ensemble, mais de manière trop irrégulière pour être décrite en géométrie Euclidienne. La connaissance de l’organisation microscopique du carcinome papillair...

Résumé Les spondyloarthrites constituent un groupe de maladies rhumatismales dont le point commun est l’atteinte du rachis et des articulations sacro-iliaques (ASI). Un diagnostic précoce est requis pour une prise en charge thérapeutique précoce et un meilleur pronostic. Les nouvelles molécules, en particulier anti-TNF alpha ont fait la preuve de l...

Incidental diagnosis of thyroid nodules is very common on adult neck ultrasonography (US) examination. They are primarily assessed on size and greyscale ultrasound criteria such as hypoechogenicity, taller than wide, spiculated margins and calcifications. In difficult situations Doppler US features may improve tumour characterisation and staging.

Objective: The purpose of this article is to highlight the various sonographic characteristics that should help to differentiate a restructured benign collapsed thyroid nodule from histologically proven thyroid carcinoma by different imaging means, including Doppler sonography, and fine-needle aspiration cytologic analysis. Conclusion: Benign th...

Incidental diagnosis of thyroid nodules is very common on adult neck ultrasonography examination. Thyroid calcifications are encountered in benign thyroid nodules and goiters as well as in thyroid malignancy. Depiction and characterization of such calcifications within a thyroid nodule may be a key element in the thyroid nodule diagnosis algorithm....

Background: Although being classically located inside the liver parenchyma, hemangiomas may occasionally develop outside the extra-hepatic capsule, thus appearing as a pedunculated mass. Case report: We report the case of a 66-year-old anal cancer female patient presenting with an asymptomatic sub-hepatic mass. Incidental diagnosis of a peduncul...

Background: Thyroid nodules presenting ultrasonographic (US) findings suspicious for malignancy should undergo fine-needle aspiration and further cytologic analysis according to the Bethesda 2010 classification. Benign necrotic thyroid nodules may also harbor suspicious US features as follows: ill-defined margins, taller than wide aspect, strong h...

Incidental diagnosis of a thyroid nodule is very common on adult neck ultrasound (US) examination. In such cases, extensive knowledge of thyroid nodule semiology on high frequency Doppler ultrasound and of thyroid imaging reporting and data system (TIRADS) nodule classification is mandatory.1 Thyroid nodules presenting with US findings suspicious f...

Purpose: Various venous access devices are available, including peripheral venous lines, peripherally inserted central catheters lines, and subcutaneous port catheters. The latter provides medium-to long-term venous access and includes medical devices that can be inserted either on the chest (chest ports) or in the arm (arm ports). We report the te...

Resume Le diagnostic du nodule thyroidien repose sur l’echographie et la classification TIRADS (Thyroid Imaging-Reporting and Database System), qui stratifie le risque de malignite en fonction des criteres echographiques. Il en decoule une prise en charge dont la cytoponction echoguidee est la pierre angulaire. Cette derniere permet de classer le n...

Le diagnostic du nodule thyroïdien repose sur l’échographie et la classification TIRADS (Thyroid Imaging-Reporting and Database System), qui stratifie le risque de malignité en fonction des critères échographiques. Il en découle une prise en charge dont la cytoponction échoguidée est la pierre angulaire. Cette dernière permet de classer le nodule t...

Further to the paper by Chng et al, entitled "Value of sonographic features in predicting malignancy in thyroid nodules diagnosed as follicular neoplasm on cytology", published in the 2014 December issue of Clinical Endocrinology, we wish to make the following comments: (a) We agree that a high TIRADS score such as TIRADS 4C and TIRADS 5 are consid...

Background Hereditary hemorrhagic telangiectasia (HHT) and hepatopulmonary syndrome are disorders characterized by the development of multiple pulmonary arteriovenous malformations (PAVM). Presentation of the hypothesis COX2 may be at the origin of a cascade of pro inflammatory events to favour angiogenesis and PAVM development. Testing the hypot...