Alexandra Sousa

• Master of Pharmacy
• PhD Candidate at UiT The Arctic University of Norway

Biofilms present a great challenge in antimicrobial therapy due to their inherent tolerance to conventional antibiotics, promoting the need for advanced drug delivery strategies that improve therapy. While various nanoparticles (NPs) have been reported for this purpose, DNA-based NPs remain a largely unexploited resource against biofilm-associated...

Nucleic acid-based materials showcase an increasing potential for antimicrobial drug delivery. Although numerous reports on drug-loaded DNA nanoparticles outline their pivotal antibacterial activities, their potential as drug delivery systems against bacterial biofilms awaits further studies. Among different oligonucleotide structures, micellar nan...

Bacterial biofilms are highly protected surface attached communities of bacteria that typically cause chronic infections. To address their recalcitrance to antibiotics and minimise side effects of current therapies, smart drug carriers are being explored as promising platforms for antimicrobials. Herein, we briefly summarize recent efforts and cons...

In last years, the scientific community has been met with an emerging use of natural compounds instead of chemical compounds in medicines, food supplements, cosmetics and dermatological products. Another fact that scientific community has remarked is the use of nanotechnology, mainly applied into cosmetic and pharmaceutical industries. In this cont...

Breast cancer is one of the most commonly diagnosed forms of cancer and one of the most common causes of cancer death in women. The therapy for breast cancer has substantially progressed, but so far and in some types of breast cancer, discrete progress has been made in terms of clinics. Depending on clinical tumor subtype (ER-positive, PR-positive,...