Alexandra Perebikovsky

University of California, Irvine | UCI · Department of Physics and Astronomy

Heterogeneous immunoassays (HI) are an invaluable tool for biomarker detection and remain an ideal candidate for microfluidic point-of-care diagnostics. However, automating and controlling sustained fluid flow from benchtop to microfluidics for the HI reaction during the extended sample incubation step, remains difficult to implement; this leads to...

Rapid, point-of-care (PoC) diagnostics for antibiotic susceptibility testing (AST) are critical in combating the antimicrobial resistance epidemic. While new, alternative technologies are capable ofrapidly identifying antibiotic resistance, traditional AST methods, where a patient sample is in-cubated with different antibiotics, remain the most rel...

Advances in stem-cell therapy rely on new, multi-functional smart scaffolds (MSS) to promote growth while simultaneously characterizing stem cells undergoing selective differentiation. Non-destructive cell characterization techniques, such as electrochemical detection of lineage-specific metabolites, play a critical role in translational stem-cell...

In this work, we report on a rapid, efficient electrochemical iodine sensor based on mechanically treated carbon nanofiber (MCNF) electrodes. The electrode’s highly graphitic content, unique microstructure, and the presence of nitrogen heteroatoms in its atomic lattice contribute to increased heterogeneous electron transfer and improved kinetics co...

We review the utility of centrifugal microfluidic technologies applied to point-of-care diagnosis in extremely under-resourced environments. The various challenges faced in these settings are showcased, using areas in India and Africa as examples. Measures for the ability of integrated devices to effectively address point-of-care challenges are hig...

The field of centrifugal microfluidics has experienced tremendous growth during the past 15 years, especially in applications such as lab-on-a-disc (LoD) diagnostics. The strength of LoD systems lies in its potential for development into fully integrated sample-to-answer analysis systems. This review highlights the technologies necessary to develop...

doi:10.3390/mi5020171 micromachines ISSN 2072-666X www.mdpi.com/journal/micromachines Review Abstract: This review focuses on recent advances in micro-and nano-fabrication techniques and their applications to electrochemical power devices, specifically microfabricated Lithium-ion batteries, enzymatic and microbial fuel cells (biofuel cells), and dy...