Alexander Zeller

Alexander Zeller
Hannover Medical School | MHH · Cranio-Maxillo-Facial Surgery

PD Dr. med. Dr. med. dent.

About

61
Publications
3,736
Reads
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152
Citations
Introduction
Alexander Zeller currently works at the Department of Oral and Maxillo-Facial Surgery at Hannover Medical School. Alexander does research mainly concerning patient specific implants, 3D-printing and intraoperative navigation. Besides that, he is the former vice-chairman of the residents group within the German Association of Oral and Maxillofacial Surgery (DGMKG).
Additional affiliations
June 2014 - present
Hannover Medical School
Position
  • Medical Doctor
Education
August 2014 - September 2018
Hannover Medical School
Field of study
  • Dentistry
October 2012 - November 2012
Hiroshima University
Field of study
  • Medicine
July 2007 - April 2014
Hannover Medical School
Field of study
  • Medicine

Publications

Publications (61)
Article
Full-text available
Purpose Patients with oral cancer have gender-specific differences with respect to health-related quality of life (HRQoL) and psychosocial variables (PV). The aim of the present study was to evaluate HRQoL and PV outcomes in patients treated for oral squamous cell carcinoma. Methods Data of 1234 patients were collected from a multicenter rehabilit...
Article
The surgical treatment of cleft lip and palate (CLP) has been well described in the literature. Nevertheless, little is known about the psychological burden of affected parents. The aim of this study was to investigate the psychological burden in parents of children with CLP within the first 3 years of the children’s lives. A standardized questionn...
Preprint
Background: Despite its increasing popularity, to our knowledge the use of social media applications (SM) for residents’ training in Oral and Maxillofacial Surgery (OMFS) has not been investigated yet. The aim of this study was to evaluate the use of SM applications by OMFS residents for post-graduate training in Germany. Methods: For explorative a...
Article
Free flap transfer for reconstruction of intraoral defects is a common procedure in oral and maxillofacial surgery. For tumor-related defects, the radial forearm flap is widely used for soft tissue restoration. However, transfer of free skin grafts to the donor site region is often required for wound closure after free flap harvesting, resulting in...
Article
Purpose The aim of this study was to evaluate the current state of training of German interns in oral and maxillofacial surgery (OMFS) under the influence of the COVID-19 pandemic in 2021. Materials and methods A previously tested questionnaire consisting of 53 questions was sent to interns in German OMFS (non-) university hospitals and private pr...
Article
Full-text available
Purpose Dental restoration in cleft lip and palate (CLP) patients is demanding and often results in bone loss and dental implant failure. Furthermore, unfavorable conditions of hard and soft tissues as well as skeletal deformities aggravate surgical and dental treatment. Therefore, this study was designed to assess the feasibility of using a new ty...
Article
The aim of this study was to examine whether ultrasonography and three-dimensional radiological procedures produce significantly different measurement results with respect to fracture dislocation. This was a retrospective study of patients who were admitted to the department for oral and maxillofacial surgery of the Medical Highschool Hannover with...
Article
Background Lateral midface fractures occasionally require open reduction and internal fixation to restore function and facial symmetry. However, some patients retain facial asymmetry despite undergoing surgery due to hard tissue displacement or soft tissue sagging. This study aimed to determine the influence of soft tissue sagging on the postoperat...
Article
Full-text available
Objectives Oral and maxillofacial surgery (OMFS) has undergone pioneering progress through the development of three-dimensional (3D) printing technologies. The aim of this study was to evaluate the use of 3D printing at OMFS university and non-university hospitals and private practices in Germany.Materials and methodsFor explorative assessment, a d...
Article
Background: Dental rehabilitation of severe atrophic upper jaws remains challenging. A new generation of subperiosteally placed and rigid multi-vector bone-anchored patient-specific implants proposes an innovative line extension in implant dentistry. This single-center retrospective study focused on treating severely atrophic maxillae using these i...
Preprint
Open treatment of condylar base and neck fractures is widely recommended, whereas treatment of condylar head fractures is still controversial and just is removal of osteosynthesis material. In this study, bone resorption and remodelling after open treatment of condylar head fractures were three-dimensionally (3D) assessed and correlated with clinic...
Article
Full-text available
PurposeOral cancer resection can cause physical and psychological impairments that influence the quality of life (QoL). Depending on the postoperative time–distance, the occurrence and intensity of these impairments may change. We evaluated the sequelae and changes in therapy-related impairments during the postoperative course to detect association...
Article
Posttraumatic reconstruction of the neurocranium and viscerocranium is an essential part of modern oral and maxillofacial surgery, in addition to oncological surgery, surgery of congenital craniofacial deformities and dental surgery. Due to the complex anatomy of the facial skull and significant esthetic and functional demands on its reconstruction...
Article
Navigation-assisted surgery is the gold standard for complex reconstructive procedures of the midface and facial skeleton, and artificial and anatomical landmarks are often used for reference. The correct identification of these landmarks before surgery is crucial for the accuracy of the navigation system. This study aimed to investigate the human...
Article
Angriffe auf Menschen durch heimische Wildtiere sind in Deutschland ausgesprochen selten, können aber selbst in Stadtgebieten vorkommen. Oft sind es durch den Menschen aufgezogene Jungtiere, die im Erwachsenenalter auffällig werden. Ein besonders eindrücklicher Fall ereignete sich in Hannover und beschäftigte die MKG-Chirurgie an der dortigen Mediz...
Article
Full-text available
Background: Sophisticated guided surgery has not been implemented into total joint replacement-surgery (TJR) of the temporomandibular joint (TMJ) so far. Design and in-house manufacturing of a new advanced drilling guide with vector and length control for a typical TJR fossa component are described in this in vitro study, and its accuracy/utilizat...
Article
Full-text available
Objective The severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) pandemic has created hitherto unknown challenges for healthcare systems and patient care. This study aimed to analyze its influence on patient care and healthcare management in oral and maxillofacial surgery (OMFS) in Germany. Materials and methods A nationwide survey of th...
Article
Full-text available
Underlying pathomechanisms of osteoporosis are still not fully elucidated. Cell-based therapy approaches pose new possibilities to treat osteoporosis and its complications. The aim of this study was to quantify differences in human bone marrow-derived mesenchymal stem cells (hBMSCs) between healthy donors and those suffering from clinically manifes...
Article
Full-text available
Introduction: Neck dissection (ND) is a surgical procedure addressing cervical lymph nodes and metastases in patients with oral squamous cell carcinoma (OSCC). The aim of this study was to analyze clinical decisions regarding indications and variations of ND in Oral and Maxillofacial Surgery (OMFS) in Germany. Material and Methods: A nationwide sur...
Article
Purpose To examine possible changes in the emergency patient volume and reasons for presentation to an oral and maxillofacial surgery department during the coronavirus disease 2019 (COVID-19) pandemic and the resulting contact prohibitions. We hypothesized that the pandemic would lead to fewer patients presenting with emergent conditions. Methods...
Article
Zusammenfassung Die Verwendung von patientenspezifischen Implantaten zur Rekonstruktion von Defekten des Schädels und der Kiefer hat sich in den letzten Jahren als Standard in der Mund-, Kiefer- und Gesichtschirurgie etabliert. Anfänglich wurden die zum Einsatz kommenden Implantate intraoperativ direkt an die Defektsituation angepasst. Mit dem Fort...
Article
Customized solutions for replacement of the temporomandibular joint (TMJ) along with surgical guides enable precise and fast transfer of the virtual plan to the patient. However, these guides lack information on screw vectors and length, and well-defined borders for bony resections towards the medial skull base. This retrospective study was perform...
Article
Full-text available
Background: All intraoperative navigation systems need a referencing procedure prior to utilization, usually requiring an additional CT or CBCT scan. As new techniques in the field of CAD/CAM have evolved, it seemed favorable to develop a new referencing method not relying on additional CT or CBCT scans. Methods: A digital maxillary dental scan w...
Article
Full-text available
PurposeSurgical therapy for oral cancer can lead to severe physical and psychological disorders that negatively impact patient quality of life (QoL). This study aimed to evaluate the relationship between fulfillment of patients’ information needs during oral cancer treatment and patients’ perception of posttherapeutic disorders influencing QoL.Meth...
Article
Deep and complete reconstruction of the orbital cavity has been shown to be essential for preventing enophthalmos and hypoglobus in patients with orbital defects or deformities. Additively manufactured patient-specific titanium implants provide unlimited options in design. However, implant malpositioning can still occur, even when intraoperative im...
Article
Introduction Medical biomodels can be used for illustration of medical conditions, preoperative planning or to facilitate pre-bending of osteosynthesis material. They have been shown to be an effective and efficient method to reduce operating time, blood loss and wound stress in cranio-maxillo-facial surgery. Lately, new time and cost-efficient 3D-...
Article
Full-text available
Brodie abscesses can be considered to be a very rare condition, especially in pediatric patients. In 2019, the first cranial Brodie abscess was published in a 51-year-old female following a dental procedure. In this article, we present our case of a 13-year-old boy suffering from recurrent, painless swelling in the left mandibular molar region. MRI...
Article
The aim of this study was to analyze the current situation of trainees in OMFS in a nationwide survey at German universities and teaching hospitals. A questionnaire about their training in OMFS and discrimination, gender (in-)equality, and reconcilability of work and family life was sent to many OMFS residents in Germany. Seventy-five questionnai...
Article
Full-text available
Background Conservative treatment, including observation and closed treatment, as well as open reduction and internal fixation are existing options for treating condylar process fractures. Extraoral approaches are widely preferred for open reduction and internal fixation. Transoral access for condylar base and neck fractures is not yet commonly use...
Article
Background: Concepts regarding cleft lip and palate care vary widely globally, as there is no international consensus. Consequently, institutional surveillance of cleft concepts is essential. In addition to subjective expert rankings, three-dimensional (3D) photogrammetry of the face has become the gold standard for evaluation and objective assessm...
Article
Displacement of the remaining mandibular segments may occur after alloplastic bridging of mandibular segmental defects using patient-specific reconstruction plates. Consequently, additional surgical devices are required for correct plate positioning. Patient-specific reconstruction plates with a conventional one beam-like design (cPSRP) have been m...
Article
Objectives The aim of the current study was to evaluate potential differences in the accuracy of mandibular reconstruction and long-term stability, with respect to different reconstructive procedures. Methods In total, 42 patients who had undergone primary segmental mandibular resection with immediate alloplastic reconstruction, with either manual...
Article
The aim of this study was to analyze the current situation of trainees in OMFS in a nationwide survey at German universities and teaching hospitals. A questionnaire about their training in OMFS and discrimination, gender (in-)equality, and reconcilability of work and family life was sent to many OMFS residents in Germany. Seventy-five questionnaire...
Article
The aim of this study was to asses a survey of residents to obtain relevant information about their current situation in training in Oral and Maxillofacial Surgery in Germany. Special focus was given to the personal and clinical preferences of the residents, their main subjects of interest and plans after residency. Furthermore, the different princ...
Article
Zusammenfassung Hintergrund Die Arthrodese stellt für das destruierte proximale Interphalangealgelenk eine schnelle und sichere Therapie dar. Eine Vielzahl unterschiedlicher Verfahren zur Arthrodese mit unterschiedlichem chirurgischem Aufwand ist beschrieben. Als sicherste Verfahren zählen komprimierende Verfahren. Ziel Ziel dieser Arbeit war es, m...
Article
Intraorbital space-occupying lesions always pose a challenge, both in terms of definite surgical removal as well as preoperative sampling for histopathological examination. Despite the use of modern high-resolution imaging techniques, the dignity of orbital lesions can often not be determined with sufficient certainty preoperatively. As the amount...
Article
Purpose: Medication-related osteonecrosis of the jaw (MRONJ) is an adverse side effect of antiresorptive and antiangiogenic therapeutic agents that is difficult to treat owing to its high relapse rate. The aim of the present study was to determine whether patients with MRONJ treated using decortication and a nasolabial flap compared with those who...
Article
Background: To construct a fracture-specific reduction aid by means of virtual reduction technology and 3D printing to reduce malreduced, externally fixed, long bone fractures. Technique: Following application of an external fixator to a malreduced long bone fracture, we performed postoperative computed tomography to visualise the fragments and...
Article
Objectives: Orbital surgery is a challenging procedure because of its complex anatomy. Training could especially benefit from dedicated study models. The currently available devices lack sufficient anatomical representation and realistic soft tissue properties. Hence, we developed a 3D-printed simulation device for orbital surgery with tactual (ha...
Poster
Full-text available
Vorteil einer volldigitalen Operationsplanung in der Dysgnathie-Chirurgie ist die durch den Chirurgen vorgenommene zuverlässige Analyse der dreidimensionalen Konfiguration und Relation von Maxilla und Mandibula in Bezug zur Schädelbasis. So können insbesondere komplexe Kiefer- und Gesichtsdeformitäten besser dargestellt und bewertet werden. Die hie...
Poster
Full-text available
Vorteile einer volldigitalen Operationsplanung in der Dysgnathie-Chirurgie ist die durch den Chirurgen vorgenommene zuverlässige Analyse der dreidimensionalen Konfiguration und Relation von Maxilla und Mandibula in Bezug zur Schädelbasis. So können insbesondere komplexe Kiefer- und Gesichtsdeformitäten besser dargestellt und ausgewertet werden. Die...
Article
Full-text available
Mandibular reconstruction today is still one of the larger challenges in cranio maxillofacial surgery. Quality of life can be extremely reduced by tissue defects in the mandible region, whether caused by trauma or tumour; it is a central concern of all CMF surgeons to improve mandibular reconstruction. Over the last few years rapid progress in CAD/...
Article
The two-shot technique is an effective stopping power method. The precise mechanisms of action on the bone and soft-tissue structures of the skull; however, remain largely unclear. The aim of this study is to compare the terminal ballistics of the two-shot and single-shot techniques. 40 fresh pigs' heads were randomly divided into 4 groups (n = 10)...

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Projects

Projects (4)
Project
To investigate feasible applications of 3D-Printing in maxillofacial surgery and its adjacent subjects.