Alexander I. Konovalov

• Doctor of Chemistry, Professor, Full member of RAS
• Group Leader at Russian Academy of Sciences

Self-organization, physicochemical properties (specific electrical conductivity, surface tension), UV absorption, and fluorescence of aqueous herbicide compositions based on N-(phosphonomethyl)glycine and plant growth regulator succinic acid (SA) were studied in a range of herbicide concentrations of 1·10−19−1·10−1 g L−1 at the constant concentrati...

A variety of physicochemical methods were used to examine the self-organization, physicochemical, UV absorption, and fluorescent properties of diluted aqueous solutions (calculated concentrations from 1·10⁻²⁰ to 1·10⁻² M) of the membrane voltage-dependent potassium channels blocker 4-aminopyridine (4-AP). Using the dynamic light scattering method,...

A variety of physicochemical methods were used to examine the self-organization, physicochemical, UV absorption, and fluorescent properties of diluted aqueous solutions (calculated concentrations from 1·10−20 to 1·10−2 M) of the membrane voltage-dependent potassium channels blocker 4-aminopyridine (4-AP). Using the dynamic light scattering method,...

A variety of physicochemical methods were used to examine the self-organization, physicochemical, UV absorption, and fluorescent properties of diluted aqueous solutions (calculated concentrations from 1·10−20 to 1·10−2 M) of the membrane voltage-dependent potassium channels blocker 4-aminopyridine (4-AP). Using the dynamic light scattering method,...

The relationship between non-monotonic concentration dependencies of the size of the dispersed phase (nanoassociates), physicochemical properties (specific electrical conductivity, pH), and fluorescence intensity (λex 225 nm, λem 340 nm) of a multi-component dispersed system based on herbicide N-(phosphonomethyl)glycine and its effect on the develo...

The issue of protecting aquatic ecosystems from biologically active compounds (BACs) such as pesticides and pharmaceuticals detected in aquatic environments at low concentrations has become urgent. Presently, literature provides much information about BACs that at low concentrations cause significant damage to hydrobionts, but a physicochemical exp...

Diclofenac sodium (DS) is a widely used nonsteroidal anti-inflammatory drug (NSAIDs). NSAIDs are poorly removed during standard wastewater treatment. The consequences of the presence of NSAIDs in rivers and lakes at 10-11-10-8 mol/L are not yet established; therefore, ecotoxicologists have focused their efforts on studying the effect of low-concent...

The synthesis and study of self-association and encapsulation ability of new low toxic conjugate of tetraphenyleneoxypentylcalix[4]resorcinarene and methoxy-poly(ethylene glycole) (C 5 OPh-mPEG) were described. The conjugate is characterized by ¹ H, ¹³ C NMR, FT-IR, MS, SLS methods. In an aqueous solution the conjugate form multimicellar nanopartic...

It has been shown for the first time that aqueous solutions of quaternary phosphonium salts (cetyltributylphosphonium bromide, cetyltriphenylphosphonium bromide) in the range of 1 × 10⁻²–1 × 10−18 mol/L are disperse systems. The nature of the disperse phase changes as the solution is diluted, starting from micelles (1 × 10⁻⁴–1 × 10−2 mol/L), transl...

A relationship between the nonmonotonic concentration dependences of the size of the dispersed phase (nanoassociates), physicochemical properties (electric conductivity, pH, redox potential), and fertility of hydrobionts under the action of solutions of citric (CA) and succinic (SA) acids in low concentrations was established. Solutions of CA stimu...

The reasons for the very high reactivity and variability of reactivity of two dienophiles, tetracyanoethylene (1) and 4-phenyl-1,2,4-triazoline-3,5-dione (2), in the Diels–Alder reactions were considered. The data on the rate of reactions with anthracene (3), benzanthracene (4) and dibenzanthracene (5) in 14 solvents over a range of temperatures an...

Small (dcore ≈ 2–5 nm) well-dispersed gold nanoparticles (AuNPs) stabilized by amphiphilic octacarboxy-calix[4]resorcinarenes with different substituents on the lower rim—methyl (С1–CR), pentyl (С5–CR) and undecyl (С11–CR)—in an aqueous solution were obtained. The nanoparticles were studied by spectrophotometry, transmission electron microscopy, FT...

In order to obtain a non-toxic amphiphilic calixresorcinarene capable to form nanoconjugates for drug encapsulation, tetraundecylcalixresorcinarene functionalized by methoxy poly(ethylene glycol) chains has been synthesized. The macrocycle obtained is characterized by low hemotoxicity. In aqueous solution it forms nanoassociates that are able to en...

Additional experimental data.

The effects of temperature, solvent nature, and high hydrostatic pressure on the rate of the ene reaction of 4-phenyl-3H-1,2,4-triazole-3,5(4H)-dione with β-pinene have been studied. The reaction gives only one product and is accompanied by a large heat effect. Comparison of the activation and reaction volumes indicates cyclic structure of the tran...

The data on temperature, solvent, and high hydrostatic pressure influence on the rate of the ene reactions of 4‐phenyl‐1,2,4‐triazoline‐3,5‐dione (1) with 2‐carene (2), and β‐pinene (4) have been obtained. Ene reactions 1+2 and 1+4 have high heat effects: ∆Hr‐n (1+2) −158.4, ∆Hr‐n(1+4) −159.2 kJ mol⁻¹, 25°C, 1,2‐dichloroethane. The comparison of th...

Novel polymer nanospheres (p(SRA-B)) were prepared by cross-linking a sulfonated resorcinarene (SRA) with phenylboronic acid. p(SRA-B) shows good stability in water and can be used as a nanocontainer for the pH- and glucose-controlled substrate release. Fluorescent dyes (fluorescein, pyrene and 1,3,6,8-pyrenetetrasulfonic acid tetrasodium salt) wer...

Additional experimental data.

Here we present the consecutive study of colloid systems formed by novel isatin derivative as compound with high pharmacological potential and series of carboxyresorcinarenes. The azo-modified isatin derivative bearing ammonium moiety (I-3) was synthesized and its antimicrobial activity was investigated. To increase its solubility the solubilization...

Here we present the supramolecular surfactant-macrocycle system which properties are independent on system composition in the wide range of components concentrations. The study of the interaction of octacarboxy-tetra(p-phenylene-oxy-pentyl)calixresorcinarene (C5R) and cetylpyridinuim chloride (CPC) in mixed aqueous solutions were performed by dynam...

A set of physicochemical methods was used to establish that aqueous solutions of chloracetophos fungicide and bactericide (1) in the range of calculated concentrations from 1•10–18 to 1•10–4 mol L–1 are disperse systems in which a dispersed phase hundreds of nanometers in size is formed above and below a threshold concentration of 1•10–9 mol L–1. U...

Cooperative nanoscale associates of amido(dimethylamino) calixresorcinarenes with pentyl (C5) and undecyl (C11) substituents on lower rim with antitumor drug-methotrexate (MTX) in aqueous solution and on the surface of gold nanoparticles C5@Au and C11@Au were formed. The formation of nanoparticles was investigated by ¹H NMR, NMR FT-PGSE, 2D NOESY,...

Four new tetrasubstituted [1.1.1.1]metacyclophanes (4-7), that are inherently adopting a 1,3-Alternate conformation, bearing four or eight peripheral carboxylic binding sites, and appended with spacers group (alkyl or phenyl) differing by the flexibility, have been synthesised in high yields. The structures of the obtained compounds have been inves...

The paper describes the first synthesis of molecular tectons, a series of ligands based on thiacalix[4]arenes in the 1,3-alternate stereoisomeric form containing photoswitchable azo groups in the side chain and carboxyl groups as potential binding sites for the synthesis of photoswitchable complexes and coordination polymers. In the case of p-tert-...

The association of branched polyethyleneimine (PEI) with a series of octacarboxy-calixresorcinarenes bearing different low-rim substituents leads to the formation of nanosized supramolecular complexes. The PEI–macrocycle complexes have fine-tunable sizes regulated by variations in the self-association capacity of the calixresorcinarenes. In the sup...

This review is devoted to the scientific achievements of the departments of organic chemistry in higher schools of Russia within the past decade.

The combination, under mild conditions, of the methylenecarboxylic appended tetramercaptotetrathiacalix[4]arene (TMTCA) derivative 4, blocked in 1,3-Alternate conformation, with acetate salts of octahedral Copper(II), Manganese(II), Nickel(II) and Zinc(II), leads to the formation, in the crystalline state, of high dimensional coordination networks....

In a concentration range of 1.0–1.0 × 10–17 mol dm–3, aqueous systems based on (S)-and (R)-lysine vary in the ability to form a dispersed phase (domains and nanoassociates) hundreds nanometers in size with different UV absorption spectra of these systems.

New lower rim functionalized thiacalix[4]arenes 7 and 8 in 1,3-alternate conformation containing photoswitchable azobenzene fragments and carboxyl groups as cation binding sites were obtained. The structure of the obtained compounds was established by 1D and 2D NMR¹H spectroscopy and MALDI-TOF mass spectrometry. The ability of compounds 7 and 8 to...

The effects of temperature, solvent nature, and high hydrostatic pressure on the rate of the reaction of biadamantylidene with 4-phenyl-3H-1,2,4-triazole-3,5(4H)-dione have been estimated. Significant shielding of the C=C double bond in biadamantylidene is responsible for the high entropy and volume of activation. Quantitative yield of the reaction...

It has been shown for the first time that aqueous solutions of metaphos pesticide (1×10–4–1×10–17 mol/L) are disperse systems, the disperse phase undergoing rearrangement upon dilution. The relationship between nonmonotonic concentration dependences of the nanoassociate size, physico-chemical properties of the systems, and their action on higher pl...

In this article we report a synthesis of mono- and bimetallic Pd-Ni nanocomposites on a multicharged polymeric matrix for the catalytic application. The morphology and catalytic properties of the composites...

It is shown for the first time using a complex of physicochemical methods (dynamic and electrophoretic light scattering, conductometry, pH-metry) that below a threshold concentration of 1.0•10–7 mol L–1 the disperse phase of the aqueous systems based on moss peptide PpCLE2 undergoes the domain—nanoassociate rearrangement, which affects the nonmonot...

It was shown for the first time using a complex of physicochemical methods (dynamic and electrophoretic light scattering, nanoparticle tracking analysis, transmission electron and atomic force microscopy, conductometry, pH-metry) that in a temperature range of 25—60 °С (S)-lysine aqueous solutions (1•10–17—1•10–2 mol L–1) are disperse systems, wher...

Novel water-soluble thermoresponsive oligomers TO1 and TO2 were obtained by reaction of amidoamine tetramethylcalixresorcinarenes (C1) and tetrapentylcalixresorcinarenes (C5) with ethylene glycol diglycidyl ether. The compounds were characterised by ¹H and FT-PGSE NMR, FTIR, static light scattering and elemental analysis. The thermoresponsive prope...

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Corresponding author. Fax: +7 843 273 2253.

Kinetic parameters of the unusual [2π + 2σ + 2σ]-cycloaddition reactions of quadricyclane (1) with tetracyanoethylene (2), 4-phenyl-1,2,4-triazoline-3,5-dione (3), N-phenylmaleimide (4), and diethyl azodicarboxylate (5) are determined experimentally. Additionally, the enthalpies of 1 + 2 reaction in 1,4-dioxane solution (-236.6 ± 1.0 kJ mol⁻¹) and...

Amido(dimethylamino) calix[4]resorcinarenes with different substituents on the lower rim (-CH3 (С1), −C5H11 (C5), −C11H23 (C11)) both as reducing and stabilizing agent in an aqueous solution were used for the fabrication of stable gold colloids. Gold colloids are characterized by spectrophotometry, FTIR − spectroscopy, transmission electron microsc...

Depending on the anion (NO3⁻ or BF4⁻) and stoichiometry, the combinations of [1.1.1.1]metacyclophane adopting a blocked 1,3-alternate conformation and bearing four cyanomethylene groups with silver cations under self-assembly conditions lead to the formation of either a 1D coordination network or a discrete binuclear metallomacrocycle.

The relationship between rearrangement of the dispersed phase inducing considerable changes in the pH and nonmonotonic concentration dependences of membrane effects in aqueous systems of the endogenous regulatory peptide, thyroliberin (thyrotropin-releasing hormone), in 10–3–10–16 mol/L concentration range was demonstrated for the first time. The m...

The kinetics of the Diels–Alder (DA) reactions of 4-phenyl-1,2,4-triazoline-3,5-dione 1, trans-diethyl azodicarboxylate 2, and tetracyanoethene 3 with 1,3-cyclohexadiene 4, cycloheptatriene 5, 1,3-cycloheptadiene 6, cyclooctatetraene 7, and 1,3-cyclooctadiene 8 in a range of temperatures and pressures has been studied. Values of the enthalpy, entro...

The octacarboxylic derivative of tetrapentylcalix[4]resorcinarene (1) was used as stabilizer for preparation of silver nanoparticles (AgNPs) hydrosol. The calixresorcinarene-capped nanoparticles Ag@1 are stably dispersed in an aqueous colloid solution and have an average diameter of 4–6 nm (TEM). The interaction of the macrocycle 1, possessed the r...

The rate of the reaction between 9,10-anthracenedimethanol and maleic anhydride in 1,4-dioxane, acetonitrile, trichloromethane, and toluene is studied at 25, 35, 45°C in the pressure range of 1–1772 bar. The rate constants, enthalpies, entropies and activation volumes are determined. It is shown that the rate of reaction with 9,10-anthracenedimetha...

A method was proposed for the calculation of changes in the rate (kP/kP=0) and equilibrium constants (KP/KP=0) for chemical reactions under high hydrostatic pressure (10—20 kbar). The calculation based on the activation and reaction volume data makes it possible to select optimum conditions for slow and equilibrium chemical processes.

The association of cetylpyridinium chloride (CPC) micelles in the presence of octaacetated tetraphenyleneoxymethylcalix[4]resorcinarene (CR) leads to the formation of unusual spherical supramolecular nanoparticles (SNPs). Within the range of CR/CPC molar ratios from 10/1 to 1/10 (except for 1/8), CR, acting as a counterion, decreases the critical m...

Using a complex of physicochemical methods it has been shown for the first time that the diluted solutions (10⁻¹¹–10⁻³ M) of dodecyl derivative of p-sulfonatocalix[6]arene are disperse systems, where the role of a disperse phase is played by the supramolecular structures of different nature – micelles (above 6·10⁻⁴ M), domains (1·10⁻⁴–1·10⁻⁷ M) and...

The combination under mild conditions of the carboxylic appended tetramercaptotetrathiacalix[4]arene (TMTCA) derivative 2 blocked in 1,3-A conformation with acetate salts of octahedral copper(II), manganese(II) and zinc(II), and pyridine, leads to the formation of new 1D coordination polymers in the crystalline state. Whereas for copper(II) and man...

The design of polymacrocyclic structures is of high importance for the improvement of recognition ability to various guests. We present a convenient approach towards two types of dendrimer-shaped pentakis-thiacalix[4]arenes with triazolyl linkers using the click reaction of tetraazidoalkoxycalixarenes with monoalkynyloxy derivatives, as well as tet...

The intermolecular interaction of azobenzenesulfonate calix[4]arene with cationic surfactant CTAB was studied by a complex of physicochemical methods. The influence of calix[4]arene:CTAB ratio on the form of the aggregates in their mixed composition in the aqueous medium was determined. Single-layer vesicles are formed in the equimolar azobenzenesu...

A series of thiacalix[4]arene derivatives blocked in the 1,3-alternate conformation and bearing four carboxylic acids have been designed and synthesized. These compounds, owing to the H-bond donor (OH moiety) and acceptor (CO group) nature of the carboxylic acid moieties, behave as self-complementary tectons and lead to the formation of tubular 1D...

The rates of the Diels–Alder reaction of 9-(hydroxymethyl)anthracene and 9,10-bis(hydroxymethyl)anthracene with maleic anhydride and two maleimides, N-ethyl- and N-phenylmaleimide, have been studied at various temperatures and pressures in different solvent media. A rate acceleration in water in comparison with organic solvents is observed. Thermod...

Nanoassociates as a possible basic element of scientific foundation of homeopathy

The Diels—Alder reaction rates of 9-hydroxymethylanthracene with N-phenylmaleimide and N-ethylmaleimide in water, butan-1-ol, ethylene glycol, acetonitrile, chloroform, and 1,4-dioxane have been compared.

The water-soluble tetramethylensulfonatocalix[4]resorcinarene with methyl (C1) and pentyl (C5) substitutes on the lower rim forms colloid nanoscale aggregates with poly(diallyldimethylammonium chloride) (PDDA) in aqueous solutions. The size and stability of nanoparticles depend on concentrations of the components and their ratio in the ‘calixarene-...

In this article, we present a new polymeric nanosphere (p(MVCA-co-SS)) for redox-controlled substrate release. The nanosphere consists of a hydrophobic core with disulfide bridges stabilized by the viologen-resorcinarene cavitand shell. The nanosphere is sensitive to thiol-containing reducing agents: glutathione (GSH) and dithiothreitol (DTT). GSH...

Here we represent the first example of the formation of mixed nanoscale associates, constructed from amphiphilic calixresorcinarenes and hydrophobic carboxylic acids including drugs. The amidoamino-calixresorcinarene self-associates effectively solubilize hydrophobic carboxylic acids - drugs such as naproxen, ibuprofen, ursodeoxycholic acid and ali...

Kinetic data for the unusual [2π + 2σ + 2σ]-cycloaddition of quadricyclane to tetracyanoethylene in toluene have been obtained for the first time. The same reaction in 1,4-dioxane appears to be the most exothermic among known cycloaddition reactions. The entropy of activation and reaction volume differ only slightly from the corresponding parameter...

Using a combination of physicochemical methods (dynamic and electrophoretic light scattering (DLS and ELS, respectively), nanoparticle tracking analysis, atomic force and transmission electron microscopy (AFM and TEM, respectively), UV spectroscopy, conductometry, pH-metry, dielcometry), it was found that dilute solutions of a multicomponent drug i...

The slide-show and lecture on You Tube by Academician Alexander I. Konovalov et al., related to this poster, are available in the site of: Conference of the Physics, Chemistry and Biology of Water, Bulgaria 2014. The slide-show is available at -- http://www.waterconf.org/participants-materials/2014/Presentations/Alexander_Konovalov_Water_Conference...

The aggregation of octa-2-hydroxyethylated calix[4]resorcines (CR) with different alkyl chain length (R = Et, n-C5H11, n-C11H23), hydrophobically modified polyethyleneimine (HPEI) and their mixed systems was investigated by the tensiometry and dynamic light scattering in water and water-organic solvents at different temperatures. The critical aggre...

The synthesis and structure of thiacalix[4]monocrowns in 1,3-alternate configuration substituted by terpyridyl fragments on the lower rim are being discussed. It has been shown that the number of oxyethylene units in oligoethylene glycol chain affects the distribution of the yields of the cross-linking products leading to either thiacalix[4]monocro...

Micellar catalytic systems based on new purine-containing amphiphile for hydrolytic decomposition of organophosphorus toxicants have been prepared. The aggregation threshold of the system has been estimated by means of tensiometry, conductometry, spectrophotometry, and dynamic light scattering. The solubilizing action of the amphiphile towards the...

Nanocapsules containing pyrene, a fluorescent probe, are formed on micelles of a cationic surfactant by layer-by-layer deposition of oppositely charged polyelectrolytes (polyacrylic acid/ polyethyleneimine). Approaches, which allow to evaluate the release time of pyrene from the capsules are developed. The synthesized capsules make it possible to s...

New bifunctional derivatives of 1,3-alternate tetrathiacalix[4]arene decorated by carboxylic, ester, hydrazide and/or hydrazone groups have been synthesized with good yields using the tetrathiacalix[4]arene derivatives with incorporated pairs of carboxylic and ester groups as versatile building blocks. The structural peculiarities of the obtained b...

1D Tubular-type and 3D diamond-like coordination polymers are formed upon ombining pyridyl appended p-tertbutyltetrathiacalix[4]arene in 1,3-alternate conformation tectons 4 and 5 with mercury(II) chloride.

An amphiphilic resorcinarene with ferrocene groups at the lower rim has been applied as both reductant and stabilizer in the synthesis of colloidal silver nanoparticles. The structure of the nanocomposite obtained was investigated by transmission electron microscopy, atomic force microscopy, X-ray powder diffraction, dynamic light scattering, and U...

The sizes (hydrodynamic diameter) and ζ potentials of sodium N-acryloyl-11-aminoundecanoate and poly(sodium N-acryloyl-11-aminoundecanoate) with molecular weights of 10 000, 100 000, and 250 000 were determined using dynamic light scattering. The particle size of the formed aggregates of the macromolecules depends on the molecular weight. The value...

The self-assembly of tetrathiacalix[4]arene and tetraoxacalix[4]arene molecules functionalized by hydrazide groups was studied by DFT calculations at B3LYP/6-31G(d,p) level. The calculations were performed for the cone and 1,3-alternate conformations. The associates of calix[4]arenes in the cone conformation are stabilized by multiple hydrogen bond...

Supramolecular nanocontainers based on monocationic and gemini surfactants and oppositely charged polyelectrolytes (polyacrylic acid, polyethyleneimine) for the stabilization and enhancement of solubility of hydrophobic quantum dots CdSe/ZnS were formed. The size (from 2 to 70 nm depending on the type of nanocontainers) and shape of aggregates cont...

Quantum chemical study of the reaction of ethylene carbonate with methanol associates at the B3LYP/6-311++G(df,p) level of theory revealed two probable mechanisms. The one-step mechanism involves SN2 substitution at the sp 2-hybridized carbonyl carbon atom, while the two-step mechanism implies nucleophilic addition to the carbonyl group with format...

The aggregation properties of supramolecular systems based on polyethyleneimines and cationic surfactants with a bicyclic head group — mono- and diquaternized derivatives of 1,4-diazabicyclo[2.2.2]octane are studied by surface tension measurements, potentiometry, conductivity measurement, and dynamic light scattering. The critical aggregation conce...

It is established by spectrophotometry that polyethyleneimines, mono- (MQD) and diquaternized (DQD) hexadecyl derivatives of 1,4-diazabicyclo[2.2.2]octane, and mixed polymercolloid systems based thereon catalyze the hydrolysis of p-nitrophenyl alkyl chloromethylphosphonates. The catalysis efficiency depends on the structures of substrate, 1,4-diaza...

The rate of an ene reaction between cycloheptatriene and trans-diethylazodicarboxylate in 1,2-dichloroethane was studied at various pressures and temperatures. The results obtained were compared with kinetic parameters of some other reactions.

The internal structure of DNA lipoplexes with hydroxyethylated alkylammonium gemini surfactants (GS) with high transfection activity was studied by circular dichroism. It was shown that the efficiency of transfection of HEK293T cells with the pEGFP-N1 circular plasmid was different from zero only in the region of existence of chiral supramolecular...

Spectrophotometry was used to study the catalytic effects of the systems composed of N-monoand N, N-dialkylated 1, 4-diazabicyclo[2.2.2]octanes and lanthanum nitrate on the hydrolysis rate of O-alkyl O-4-nitrophenyl chloromethylphosphonates (Alk = Et, Bun, and n-hexyl). The mechanism of action and efficiency of the catalytic system depend on the st...

In the course of systematic study of self-organization and properties of diluted solutions of biologically active compounds (BACs), an unknown phenomenon has been discovered. Using a complex of physicochemical methods, it has been shown for the first time that diluted aqueous solutions of many BACs in a wide range of calculated concentrations (10–6...

A crystal structure and aggregation properties of trinbutyl(octadecyl)phosphonium tetrafluoroborate were studied. Palladium nanoparticles stabilized by this phosphonium salt exhibit different catalytic activity in the Suzuki reaction, depending on the concentration of the stabilizing agent, which is related to the supramolecular organization of the...

The enthalpies of the Diels–Alder reactions of twenty dienes with two active dienophiles, tetracyanoethylene and 4-phenyl-1,2,4-triazoline-3,5-dione, are compared, and the corresponding relationship between them was obtained. The values of enthalpies of very slow and/or equilibrium reactions were calculated from the obtained relationship. These dat...

Results of development of novel original methods of isolation of the pectic polysaccharide (pectin) from amaranth (Amaranthus cruentus L.) have been summarized and systematized. The technology of its integrated processing has been suggested, which is based on the extraction of pectin, rutin and plant protein from the dried amaranth biomass within o...

Lower-rim substituted bis- and tetrakis(alkynyloxy)thiacalix[4]arenes in cone and 1,3-alternate configurations were synthesized by the Mitsunobu reaction, and their structure was determined using homoand heteronuclear one- and two-dimensional NMR techniques. Bis(prop-2-yn-1-yloxy)thiacalix[4]arene was found to exist in conformational equilibrium wh...

Aqueous solutions of (S)-, (R)-, and (SR)-methionines (1?3); carbamide (4); (S)-, (R)-, and (SR)-N-carbamoylmethionines (5?7); glycoluril (8); and glycolurils containing (S)and (R)-methionine moieties (9 and 10) kept under natural and hypoelectromagnetic conditions were studied in comparison by a complex of physicochemical methods (dynamic and elec...

The B3LYP/6-311++G(df,p) quantum-chemical simulation has revealed that linear associates of methanol catalyze the ketone-enol, nitro-aci-nitro, and carbamate-azomethinenol tautomeric transformations. All the reactions proceed via the coherent transition states. The catalytic effect is enhanced with the increased alcohol degree of association. The a...

The work introduces smart organic-inorganic hybrids with temperature- and substrate-induced quenching and sensitization of hexamolybdenum iodine cluster-centered luminescence based on iodine cluster salt [K(diglyme) (CH3CN)]2[Mo6I14] (1) and triblock copolymer (PEO)13(PPO)30(PEO)13 (L64). Formation of supramolecular assembly of [Mo6I14]2−, K+, and...

Two tetrasubsituted derivatives of tetramercaptothiacalix[4]arene in 1,3-alternate conformation bearing either four (3-cyano)propyl (1) or (4-cyano)benzyl (2) moieties have been synthesized and characterized in solution as well as in the solid state by X-ray diffraction on single crystals. Their propensity to form coordination networks was investig...

MALDI-TOF mass spectrometry was used to study the reaction of p-tert-butylthiacalix[4]arene (1) and a number of its derivatives disubstituted at the lower rim (2—9) with monovalent metal salts (Li, Na, K, Cs, Cu, Ag) in the gas phase. It was shown that the thiacalixarenes under study bind the metal ions through the substitution of hydrogen atoms of...

In this paper we report a synthesis of Pd nanoparticle clusters obtained with the Pd nanoparticles assembled on the surface of spherical polymer network. The network exhibits flexibility and adapts to the cluster formation. The nanocluster displays high catalytic activity toward p-nitrophenol reduction and the Suzuki-Miyaura coupling reaction.

Complexation of decanucleotide (GCGTTAACGC) with mono- and dicationic surfactants (hydrodynamic diameter of lipoplexes ≤200 nm) is accompanied by the compensatory change of electrokinetic potential from −54 to +50 mV. The complexation efficiency considerably increases with introduction of a hydroxyethyl fragment into the surfactant head group.

The aim of this work is the development of stable fluorophore-quencher pairs with a controlled response for bioassay in the laboratory. The widely used in bioanalysis pyrene and its water-soluble derivative were selected as organic fluorophores. Water-soluble aminomethylated calixarene with sulfonatoethyl groups at the “lower rim” was chosen as a s...