Alexander Heinze

Marienkrankenhaus Hamburg · Department of Urology

Purpose: Positive surgical margins (PSM) represent a poor prognostic factor at radical prostatectomy (RP). To investigate the impact of PSM, its length, the focality and the Gleason grade at the PSM, on the oncologic outcomes in nonorgan-confined RP patients. Methods: Within a high-volume center database, we identified patients who harbored non-...

Purpose To investigate the concordance of biopsy and pathologic International Society of Urological Pathology (ISUP) grading in salvage radical prostatectomy (SRP) patients for recurrent prostate cancer. Methods Within a high-volume center database, we identified patients who underwent SRP for recurrent prostate cancer (PCa) between 2004 and 2020....

El libro de Urología clínica es una obra que permite al lector tener una idea global de los principales padecimientos urológicos. Es una excelente herramienta para abordar cada entidad de manera integral. La obra incluye descripciones detalladas de cómo realizar un adecuado interrogatorio, identificar los hallazgos clínicos más relevantes, así como...

Context: Although miniaturized percutaneous nephrolithotomy (mPCNL) and retrograde intrarenal surgery (RIRS) are both options for treating >1cm kidney stones, controversies exist on whether one is more effective and safer than the other. Objective: To systematically appraise randomized trials comparing the effectiveness and safety of mPCNL and R...

The Spanish version of the Wisconsin Stone Quality of Life (WISQOL) questionnaire was developed and validated. A double-back translation of the WISQOL was conducted and syntactic amendments were made, resulting in the Spanish version of the WISQOL (S-WISQOL) which then went through a readability analysis. Stone formers from two hospitals in Mexico...

Background The unexpected coronavirus disease 2019 (COVID-19) pandemic has spread worldwide rapidly, developing into a global health crisis. At the same time, it has seriously impacted the daily activities in all the fields of urology. Objective To better understand the impact of the COVID-19 pandemic on clinical, academic, and scientific activiti...

Radiomics texture analysis offers objective image information that could otherwise not be obtained by radiologists′ subjective radiological interpretation. We investigated radiomics applications in renal tumor assessment and provide a comprehensive review. A detailed search of original articles was performed using the PubMed-MEDLINE database until...

Impresión 3D y sus beneficios en el campo de la educación médica, entrenamiento y asesoría del paciente. 3D printing and its benefits in the field of medical education, training and patient counseling. Resumen: La impresión digital en 3D ha adquirido una gran importancia en muchas áreas, incluida la medicina y, en particular, la cirugía. Es una téc...

Background: To analyze oncological outcomes of very high-risk patients with initial PSA 50-99.9 and ≥100 ng/ml who underwent radical prostatectomy (RP) for clinically localized prostate cancer. Methods: Overall, 2,811 RP patients (1992-2018) with negative preoperative CT-scan and bone scintigraphy were included. The impact of preoperative PSA le...

Background: To examine the impact of different pretreatment definitions on biochemical recurrence (BCR)-free survival, metastasis-free survival, and cancer-specific survival after radical prostatectomy. Methods: Overall, 26,364 patients with clinically localized disease who underwent radical prostatectomy at a single institution (1992-2017) were...

Objectives: Previous studies reported improved continence recovery by bladder neck sparing (BNS) in prostate cancer patients treated with robot-assisted laparoscopic radical prostatectomy (RALP), without compromising biochemical recurrence (BCR). We compared the continence outcomes, surgical margin rates, and BCR risk of BNS vs. bladder neck recon...

Background: Positive surgical margins (PSMs) represent a poor prognostic factor at radical prostatectomy (RP). To investigate the impact of PSM, its length, the focality, and the PSM Gleason, on biochemical recurrence (BCR) in organ-confined RP patients. Methods: Within a high-volume center database, we identified patients who harbored organ-con...

Background: Persistent prostate-specific antigen (PSA) represents a poor prognostic factor for recurrence after radical prostatectomy (RP). Objective: To investigate the impact of persistent PSA at 6 wk after RP on long-term oncologic outcomes and to assess patient characteristics associated with persistent PSA. Design, setting, and participants: W...

Objective: Report our experience of the management of a patient with undiagnosed retroperitoneal paraganglioma and the intraoperative complications that the theatre team faced. Case report: We present a case of a 36-year-old patient who during oncological follow-up for a previous diagnosis of parotid acinar cell carcinoma was incidentally identifi...

Penile appearance secondary to partial penectomy for penile carcinoma can significantly affect patients' quality of life. Several techniques have been described to overcome these adversities; nevertheless, glans reconstruction remains a major surgical challenge. While cutaneous flaps do not achieve adequate cosmetic results,1 the main disadvantage...

Purpose of review: To provide a summary of surgical outcomes in percutaneous nephrolithotomy (PCNL) according to various techniques and tract sizes. Recent findings: Recent literature in this field concluded that standard PCNL (sPCNL) remains the optimal treatment for stones between 1 and 2.5 cm and can be managed with tracts 14-20 F, whereas sm...

Objective To determine the impact of imperative or elective indications on the perioperative, functional and oncological outcomes of patients undergoing robot‐assisted partial nephrectomy. Methods Between June 2006 and September 2016, data of patients who underwent robot‐assisted partial nephrectomy at the Onze‐Lieve‐Vrouwziekenhuis Hospital in Aa...

The present chapter aims to give an overview of the importance of training in robotic surgery. It includes the past experiences in robotic urological surgery, the introduction of virtual reality simulation and more advanced training modalities as the wet lab and modular training. This text will highlight the major problems encountered when developi...

Secondary bladder neck sclerosis represents one of the more frequent complications following endoscopic, open, and other forms of minimally invasive prostate surgery. Therapeutic decisions depend on the type of previous intervention (e.g., radical prostatectomy, TURP, HoLEP, radiotherapy, HIFU) and on associated complications (e.g., incontinence, f...

Condyloma acuminata is caused by the proliferation of squamous epithelial cells in the presence of human papilloma virus (HPV) infection. There are several treatment options available for anogenital warts, however, none have proven to be more efficacious. We present the case of a 3 year-8 months-old male, diagnosed with human immunodeficiency virus...

We present the case of a 3 year-8 months-old male, diagnosed with human immunodeficiency virus (HIV) infection, who presented with multiple warts in the anogenital region. Lesions were treated with imiquimod 5%, electrosurgical resection and interferon α-2b. Combination of electrofulguration and interferon α-2b is an effective treatment option for...

Background: Percutaneous nephrolithotomy (PNL) is the treatment of choice for stones > 2. cm and for those of greater density. Aims: The aim of this article was to report on the experience in kidney stone management through PNL at a regional referral hospital center. Material and methods: A retrospective study was conducted that included patients p...