Alexander Linden ClarkeUniversity of California, San Francisco | UCSF · Department of Anesthesia and Perioperative Care
Alexander Linden Clarke
Physician scientist, anesthesiologist. Visiting Assistant Professor at UCSF. Medicine and technology.
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Citations since 2017
5 Research Items
Background The global pandemic of novel coronavirus (SARS-CoV-2) has led to global shortages of ventilators and accessories. One solution to this problem is to split ventilators between multiple patients, which poses the difficulty of treating two patients with dissimilar ventilation needs. A proposed solution to this problem is the use of 3D-print...
The global COVID‐19 pandemic has led to a worldwide shortage of ventilators. This shortage has initiated discussions of how to support multiple patients with a single ventilator (ventilator splitting). Ventilator splitting is incompletely tested, experimental and the effects have not been fully characterised. This study investigated the effect of v...
The ongoing pandemic of SARS‐CoV‐2 virus and its associated disease COVID‐19 has resulted in widespread ventilator shortages and rationing of care. Massive global supply chain disruption and quarantine measures prevent equipment movement and medical device production.
Background: Ultrasound-guided techniques improve outcomes in regional anesthesia when compared with traditional techniques; however, this assertion has not been studied with novices. The primary objective of this study was to compare sensory and motor block after axillary brachial plexus block when performed by novice trainees allocated to an ultr...
Background and objectives: The objectives of this study were to determine the learning curve for capturing sonograms and identifying anatomical structures relevant to ultrasound-guided axillary brachial plexus block and to determine if massed was superior to distributed practice for this core sonographic skill. Methods: Ten University of Melbour...
Aim: To determine if the addition of adrenaline, clonidine, or their combination altered the pharmacokinetic profile of levobupivacaine administered via the caudal epidural route in children. Methods: Children aged <18 years old scheduled to undergo sub-umbilical surgery were administered caudal levobupivacaine plain 2.5 mg · ml(-1) or with adju...